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Description: In This Issue: Going With the Flow, Cam Innovations, Pain & Inflammation, and Liver & Kidney Support

www.naturalpractitionermag.com May 2016 V Na tur SO ISI T alP U ra RC OU cti EB R tio ne OO ON rM ag K T LIN .co O E m DA So Y ur ce bo ok A VRM Media Publication Go to www.naturalpractitionermag.com davinci for info about this advertiser Go to www.naturalpractitionermag.com americasfinest for info about this advertiser TABLE OF CONTENTS May 2016 VOLUME 5 NO. 3 16 FEATURES 16 The Inflammatory Protocol Mitigating pain and inflammation with the right tools can lead to a better quality of life. 20 40 COLUMNS 4 Editor s Note 40 Supplement Science 8 Practitioner Corner 34 Product Focus Liver & Kidney Support 20 Going With the Flow Hormonal changes impact women daily-- natural practitioners can assist vibrant women to live their best lives. 24 2016 CAM Innovations This special section comes in response to the desire for a greater understanding of the research and history behind the products available to practitioners and their patients and manufacturers wanting to offer the science behind the effectiveness of their products. DEPARTMENTS 10 Health Industry News 38 Practitioner Chat 42 Natural Health Studies 46 Natural Marketplace 47 Media Corner 48 Conferences & Events 48 Advertiser Index Visit NaturalPractitionerMag.com FreeProductInfo for FREE Product Information or Samples from All Natural Practitioner Advertisers FREE Subscription (Print Digital or BOTH) FREE E-newsletter Visit NaturalPractitionerMag.com Copyright 2016. Natural Practitioner (ISSN 2331-2580) Volume 5 Number 3 May 2016. Natural Practitioner is published monthly (except for bimonthly January February March April June July and September October) by VRM Media 431 Cranbury Road Suite C East Brunswick NJ 08816 USA Phone (732) 432-9600 Fax (732) 432-9288. All rights reserved including the right to reproduce in whole or in part. Not responsible for unsolicited material. Opinions expressed in by-lined articles or advertisements are not necessarily those of Natural Practitioner or its owners. Publisher is not liable for advertiser product claims or representations. Advertisers assume total responsibility for the contents of their advertisements. No portion of this magazine is intended to diagnose treat cure or prevent any disease. Printed in U.S.A. Basic annual subscription rate is 50.00. POSTMASTER Send address changes to Natural Practitioner P.O. Box 15246 North Hollywood CA 91615-5246. Subscription Customer Service Natural Practitioner P.O. Box 15246 North Hollywood CA 91615-5246 USA Phone (818) 286-3169 Fax (800) 869-0040 nprcs magserv.com www.naturalpractitionermag.com. Back Issues & Single Copies For order information contact (732) 432-9600 or info naturalpractitionermag.com. December issue is 25.00. All other issues are 10.00 each. 2 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com advancednaturals for info about this advertiser EDITOR S NOTE Finding the Allergy Solution llergies are the bane of my existence. During my junior year of college I woke up one morning with a headache that lasted off and on for about a month. Convinced that there was something severely wrong with me I made an appointment at the university health center to see a doctor. After examining me he told me that I was not dying (yes I entered my symptoms into WebMD which caused me to be overly dramatic) but that I simply was suffering from seasonal allergies and all I had was a sinus headache. But I don t have allergies I told the doctor. Well you do now he responded. And I ve had allergies ever since. According to the Asthma and Allergy Foundation of America (AAFA) allergic conditions are the most common health issue affecting children in the U.S. Further researchers believe that nasal allergies affect approximately 50 million people in the United States. And it seems that allergies are only increasing as researchers found they affect as many as 30 percent of adults and 40 percent of children. But allergies go beyond sinus headaches runny noses and watery eyes. In my Practitioner Chat column (see page 38) with Leo Galland MD and Jonathan Galland JD authors of the new book The Allergy Solution Unlock the Surprising Hidden Truth about Why You Are Sick and How to Get Well they explained that people A who suffer from weight gain stomach aches insomnia brain fog depression etc. may have a hidden allergy. A hidden allergy is often the culprit. Chronic conditions that were previously diagnosed as autoimmune diseases psychiatric disorders or many others wind up being allergic in origin. And when I asked Dr. Galland and Jonathan Galland why we are seeing a rise in allergic disorders they explained that while allergies were once rare they affect more than one billion people today. Environmental toxicity depletion of beneficial intestinal bacteria and fast food all contribute to allergies. Environmental toxins damage your body s surfaces like the respiratory or intestinal lining or the skin. The damaged lining tissue becomes a site where allergy develops. In the book the authors revealed the proven role of allergy in causing weight gain fatigue headache joint and muscle pain a range of digestive symptoms from heartburn to diarrhea mood problems poor mental focus and more. Further the book offers a step-by-step method for determining if you have hidden allergies. And for those with classic allergies like rhinitis eczema or who have asthma the program addresses these issues from a nutritional and lifestyle perspective. I don t know about you but I ll be trying out the Gallands recommendations immediately no doubt along with many more who have suffered through allergy symptoms. PUBLISHER DANIEL MCSWEENEY EDITORIAL DIRECTOR DanM VRMmedia.com ASSOCIATE PUBLISHER RUSS FIELDS RussF VRMmedia.com ADVERTISING GARY PFAFF SALES MANAGER GaryP VRMmedia.com EDITOR-IN-CHIEF SHARI BARBANEL ShariB VRMmedia.com ASSISTANT EDITOR CORINNE ANDERSON CorinneA VRMmedia.com CONTRIBUTING EDITOR JANET POVEROMO JanetP VRMmedia.com ART DIRECTOR ROBERT CERTO PRODUCTION MANAGER RobertC VRMmedia.com PRODUCTION ASSISTANT BRYAN ZAK GRAPHIC ARTIST BryanZ VRMmedia.com CIRCULATION MANAGER ROSIE BRODSKY Rosie StarkServices.com VRM MEDIA 431 Cranbury Road Ste. C East Brunswick NJ 08816 PHONE (732) 432-9600 FAX (732) 432-9288 E-MAIL info VRMmedia.com WEBSITE www.naturalpractitionermag.com PRESIDENT DANIEL MCSWEENEY DanM VRMmedia.com MISSION STATEMENT Natural Practitioner magazine provides alternative complementary and integrative health care professionals information about natural products market trends industry news health research and other content designed to benefit their practices and improve their business results. Subscription Customer Service To order a subscription or manage your account please contact us at Natural Practitioner P.O. Box 15246 North Hollywood CA 91615-5246 USA Phone (818) 286-3169 Fax (800) 869-0040 nprcs magserv.com www.naturalpractitionermag.com Back Issues See the Table of Contents page for price and order information. Connect With Us www.twitter.com www.facebook.com www.linkedin.com www.instagram.com www.pinterest.com vitaminretailer vitaminretailermagazine company vrm-media vitaminretailermagazine vrm_media 4 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com kyowa for info about this advertiser Meet Natural Practitioner s Editorial Advisory Board In its search to provide readers with insight and perspective that will help them build and better their practices Natural Practitioner has culled together an Editorial Advisory Board of authoritative practitioners willing to do just that. You will see our Board members present in key editorial as well as each authoring their own column Practitioner Corner throughout the year that highlights their expertise and professional experiences. They will also lend us their perspective on trends and topics that Natural Practitioner will be covering in issues to come. Natural Practitioner s Editorial Advisory Board is comprised of Holly Lucille ND Dr. Holly Lucille is a nationally recognized licensed naturopathic physician lecturer educator and author of Creating and Maintaining Balance A Women s Guide to Safe Natural Hormone Health. Her private practice Healing From Within Healthcare focuses on comprehensive naturopathic medicine and individualized care. Outside of her practice Dr. Lucille holds a position on the American Association of Naturopathic Physicians board of directors and is on the faculty of the Global Medicine Education Foundation. She is the past president of the California Naturopathic Doctors Association where she spearheaded a lobbying effort to have naturopathic doctors licensed in the state of California. A graduate from the Southwest College of Naturopathic Medicine Dr. Lucilles commitment to naturopathic medicine has been recognized with the Daphne Blayden Award and more recently the SCNM Legacy Award. Shailinder Sodhi ND Growing up near the Himalayas Dr. Shailinder Sodhi developed an early interest in ayurvedic plants and herbs and received his BAMS (bachelor in ayurvedic medicine and surgery) degree from Dayanand Ayurvedic College in Jalandhar India in 1985. In 1993 he received a naturopathic medicine degree from Bastyr University as well as a degree in diagnostic ultrasound from Bellevue College. Dr. Sodhi practices naturopathic medicine along with his wife Dr. Anju Sodhi and his brother Dr. Virender Sodhi at the Ayurvedic and Naturopathic Medical Clinic in Bellevue WA which he established in 1989. In addition Dr. Sodhi serves as president of Ayush Herbs Inc. a manufacturer of high-quality ayurvedic herbal formulas is an adjunct faculty member at Bastyr and has been published in several natural health magazines. Amber Lynn Vitale BA LMT CN Amber Lynn Vitale BA LMT CN majored in economics with postgraduate work in medical sciences and additional certifications in bodywork ayurveda and holistic nutrition. Her journey in the healing arts developed richly as she worked for years in practices with integrative physicians acupuncturists chiropractors and nurses. Ultimately she developed an integrated modality of ayurvedic medicine yoga advanced bodywork and integrative nutrition. Vitale uses her 19 years of experience in integrative medical practices to educate on the consumer mindset and to distill these wisdoms into digestible information bytes. In 2014 she joined the Garden of Life team as their Northeast Regional Educator. Adam Killpartrick DC Dr. Adam Killpartrick earned his degree from Palmer College of Chiropractic in Davenport IA. His primary practice focus has been a synergistic blend of NUCCA (upper cervical chiropractic) with Cranial Release Technique for which he has attained lead instructor status. Dr. Killpartrick furthered his education in clinical nutrition functional diagnostics and lifestyle medicine and has since successfully integrated this blend of specialized chiropractic care and functional medicine into his New Hampshire private practice. This practical experience led him to clinical consulting for numerous nutritional supplement companies. He is currently the chief scientific officer for DaVinci Laboratories. Jared M. Skowron ND Dr. Jared M. Skowron is a national expert in natural medicine for children. Author of the best-selling 100 Natural Remedies For Your Child his lifes work is dedicated to the optimal health of children. A faculty member at University of Bridgeport and founder of their Pediatric & Autism Clinic Dr. Skowron has helped thousands of children fulfill their optimal potential. He is vice president of the Pediatric Association of Naturopathic Physicians and his expertise is in pediatrics autism ADHD and acute and chronic EENT conditions. Jacob Teitelbaum MD A recognized authority on chronic fatigue syndrome (CFS) and fibromyalgia Dr. Jacob Teitelbaum is medical director of the Fibromyalgia and Fatigue Centers nationally and does phone consultations with CFS fibromyalgia patients worldwide. He is the author of the popular iPhone application Cures A-Z and author of the best-selling book From Fatigued to Fantastic (3rd revised edition Avery Penguin Group) and Pain Free 1-2-3--A Proven Program for Eliminating Chronic Pain Now (McGrawHill). His newest book is Beat Sugar Addiction NOW (Fairwinds Press 2010). Dr. Teitelbaum does frequent media appearances including Good Morning America CNN Fox News Channel the Dr. Oz Show and Oprah & Friends. Isaac Eliaz MD MS LAc A recognized expert in the field of integrative medicine since the early 1980s with a specific focus on cancer immune health detoxification and mind-body medicine. He is a respected formulator clinician researcher author and educator. As part of his commitment to the advancement of integrative medicine Dr. Eliaz partners with leading research institutes and has co-authored numerous peer-reviewed papers on innovative therapies for immune enhancement heavy metal toxicity and cancer prevention and treatment. He is founder and medical director of Amitabha Medical Clinic and Healing Center in Santa Rosa CA where he and his team of practitioners pioneer individualized treatments for cancer and chronic illness. 6 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com ajinomoto for info about this advertiser PRACTITIONER CORNER Triphala and Cardiovascular Health By Dr. Shailinder Sodhi riphala is an ancient and revered ayurvedic formula consisting of three fruits (amla haritaki and bahera). It is considered a rasayana or adaptogen and is a balanced tonic appropriate for all constitutions. In North America triphala is known primarily for its beneficial effects on the digestive tract. However a growing body of research supports the increasing use of this formula for cardiovascular health. Triphala has many beneficial effects on lipid metabolism in the human body. It has been shown to aid in reducing the weight of obese individuals.1 In a study in which mice were fed a high fat diet triphala administration was effective in decreasing weight gain as well as inhibiting elevation of LDL VLDL and blood glucose levels. It also increased HDL levels2 and protected liver function.3 Triphala has also been shown to decrease lipid peroxidation 4 which is a major factor in the development of atherosclerosis. Amla (Phyllanthus emblica) is the most widely known of the triphala fruits and has many diverse effects that make it very beneficial for healthy cholesterol levels. It has been shown to decrease triglyceride synthesis while increasing the synthesis of HDL. Amla also promotes the absorption of cholesterol into cells where it performs many critical T functions by increasing expression of the LDL receptor on cell surfaces.5 Amla also decreases HMG CoA reductase activity and thus the synthesis of cholesterol.6 True to its reputation as a digestive tonic it also decreased the absorption of fats and cholesterol.7 Through these diverse factors amla provides natural support for healthy cholesterol levels. Current understandings of cardiovascular disease have expanded the focus from simply looking at cholesterol levels. Endothelial dysfunction is understood to be a major factor in the development of heart disease. Studies have suggested that the anti-inflammatory and antioxidant effects of amla are beneficial in decreasing this dysfunction. A recent study on diabetic humans found that P. emblica significantly improved endothelial function and reduced biomarkers of oxidative stress and systemic inflammation in patients with type 2 diabetes mellitus without any significant changes in laboratory safety parameters. 8 A new study performed on obese adults found that in addition to the above mentioned effects amla was able to decrease platelet aggregation. The authors concluded that amla supplementation may provide beneficial effects in overweight Class-1 obese adults by lowering multiple global CVD (cardiovascular disease) risk factors. 9 These beneficial effects are compounded by the fact that another study found amla reduces CRP levels.7 It has also been shown to increase the antioxidant capacity of epithelial cells10 and promote nitric oxide production.11 An in-vitro study found that amla s antioxidant effects were due at least in part to amla s tannin content and were capable of preventing oxidative damage that leads to the progression of atherosclerosis.12 All of these findings taken together demonstrate the powerful benefits of using amla for inflammatory cardiovascular issues. Haritaki (Terminalia chebula) has very similar properties to amla in regards to heart health. Multiple studies demonstrate that it can increase HDL levels as well as lower triglycerides and LDL level.13 14 Another study looked at haritaki s ability to address the cardiovascular complications of diabetes. The study found it able to reduce glycation and the endothelial dysfunction that glycation promotes. Haritaki also decreased reactive oxygen species formation in blood vessels and monocyte adhesion to the endothelia.15 The authors found that these activities were (Continued on page 37) WWW.NATURALPRACTITIONERMAG.COM MAY 2016 8 NATURAL PRACTITIONER Go to www.naturalpractitionermag.com albion for info about this advertiser HEALTH INDUSTRY NEWS National College of Natural Medicine Announces Age Wise Institute ational College of Natural Medicine (NCNM) has announced the formation of a new institute aimed at improving the lives of senior citizens through promoting healthy active living. The new Age Wise Institute is the fourth community education institute at the college joining NCNM s Food as Medicine Traditional Roots and Women in Balance Institutes and also NCNM s renowned Helfgott Research Institute dedicated to natural medicine scientific research and education. With the number of Americans 65 and older projected to nearly double by mid-century more emphasis on the specialized needs of older people is a must noted NCNM President David Schleich. In America aging is often viewed as a disease when in fact this natural process can be supported through proper nutrition agefocused health care and supportive programs that promote staying active and connected to the community he said. Age Wise kicked off that effort January 23-24 with its first annual symposium for physicians and the general public. The focus N early detection prevention treatment and reversal of age-related dysfunction disorders and diseases. The program also highlighted innovative science and research demonstrating how to prolong a healthy lifespan and enjoy a better quality of life. NCNM plans to develop new curricula for NCNM s medical students around the issues of aging. In addition to symposia the new institute will sponsor hands-on classes community lecture series and public events. Plans are also underway to develop evidence-based research studies on prevention and treatment of age-related conditions through NCNM s Helfgott Research Institute. Joining NCNM to lead the new Age Wise Institute is Lead Gerontologist Amy Henderson. Henderson holds a master s degree from Marylhurst University in interdisciplinary studies with a concentration on gerontology. She is also founder and executive director of the Geezer Gallery a nonprofit dedicated to the empowerment and well-being of elders through art. Aging continues to be a harsh reality for many elderly Americans. Our elderly population faces desperate health conditions said Henderson. Social isolation and low economic status create major health risks often leading to Alzheimer s strokes and progressive chronic disease. In a country as wealthy as the United States the health care and living conditions available for most of our seniors is shameful Henderson added. Seniors are held in high regard in many less advanced cultures. NCNM wants to begin helping change the paradigm to help create a culture in which aging is a story of life health and dignity. For more information visit http agewiseinstitute.com. NCCAOM Launches Membership Organization for Diplomates T he National Certification Commission for Acupuncture and Oriental Medicine (NCCAOM) has announced the launch of a new national membership organization the NCCAOM Academy of Diplomates. The NCCAOM is the only national certification agency for the profession of acupuncture and Oriental medicine (AOM). The new Academy of Diplomates a separate chartered division of the NCCAOM will allow the Commission to expand our services to fulfill our dual mission to assure the safety and well-being of the public and to advance the professional practice of acupuncture and Oriental medicine said Eugene London DAOM Dipl Ac (NCCAOM) LAc Chair of the NCCAOM Board of Commissioners. The Academy enables us to go beyond certification to help our Diplomates be successful in their careers as AOM practitioners. With a potential membership of 18 000 nationally board-certified Diplomates the Academy will be governed by a separate Board of Directors. The Academy was created to serve our Diplomates and will not charge membership dues stated newly appointed Chair of the Academy of Diplomates Board of Directors David Canzone Dipl Ac (NCCAOM) Dipl NBAO DOM and our hope is to work cooperatively and synergistically with all AOM professional associations in support of the AOM profession. The new Academy of Diplomates was created based upon NCCAOM s 2014 strategic plan noted Kory Ward-Cook PhD CEO of NCCAOM. A major catalyst for its founding was feedback from our Diplomates through the 2015 Diplomate Satisfaction Survey. Some of the programs and activities to be administered under the new Academy include Offering resources to help Diplomates seeking to work in hospitals and integrative practice settings Providing free practitioner websites Expanding public awareness and profes- sional education campaigns to promote AOM and national board-certified AOM practitioners Providing tools for Diplomates to manage their practices more successfully Obtaining a standard occupational code for acupuncturist under the Bureau of Labor Statistics (BLS) Standards of Occupational Classification (SOC) system which will facilitate greater federal recognition for AOM practitioners Securing AOM representation on the American Medical Association Current Procedural Terminology (CPT) Health Care Professionals Advisory Committee Helping to assure third party reimbursement for acupuncturist-provided acupuncture by working with other integrative health care professions to insure compliance to the non-discrimination clause 2706 of the Affordable Care Act One new Academy member benefit will be a free online subscription to Meridians The Journal of Acupuncture and Oriental Medicine. Discounted print copies also will be made available to Academy members. For more information visit www.nccaom.org. 10 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com daiwa for info about this advertiser HEALTH INDUSTRY NEWS U.S. Adults Get Failing Grade in Healthy Lifestyle Behavior O nly 2.7 percent of the U.S. adult population achieves all four of some basic behavioral characteristics that researchers say would constitute a healthy lifestyle and help protect against cardiovascular disease a recent study concluded. In this study researchers from Oregon State University (OSU) and the University of Mississippi examined how many adults succeed in four general barometers that could help define healthy behavior a good diet moderate exercise a recommended body fat percentage and being a non-smoker. It s the basic health advice in other words that doctors often give to millions of patients all over the world. Such characteristics are associated with a lower risk of cardiovascular disease as well as many other health problems such as cancer and type 2 diabetes. The behavior standards we were measuring for were pretty reasonable not super high said Ellen Smit senior author on the study and an associate professor in the OSU College of Public Health and Human Sciences. We weren t looking for marathon runners. From the perspective of public health the findings of the research were not encouraging Smit said. This is pretty low to have so few people maintaining what we would consider a healthy lifestyle she said. This is sort of mind boggling. There s clearly a lot of room for improvement. Part of the value of this study the researchers said is that the results are based on a large study group 4 745 people from the National Health and Nutrition Examination Survey. It also included several measured behaviors rather than just relying on self-reported information. Measurements of activity were done with an accelerometer a device people wore to determine their actual level of movement with a goal of 150 minutes of moderate-tovigorous activity a week. Blood samples were done to verify a person was a nonsmoker. Body fat was measured with sophisticated X-ray absorptiometry not just a crude measurement based on weight and height. A healthy diet was defined in this study as being in about the top 40 percent of people who ate foods recommended by the USDA (U.S. Department of Agriculture). The lifestyle characteristics were then compared to biomarkers of cardiovascular health. Some are familiar such as blood pressure cholesterol and glucose levels. Others are more sophisticated such as Creactive protein fasting triglycerides homocysteine and other data that can provide evidence of cardiovascular risk. Many people of course accomplished one or more of the four basic lifestyle goals such as not smoking or being adequately active. The most striking finding was how few people accomplished all the goals. I would expect that the more healthy lifestyles you have the better your cardiovascular biomarkers will look Smit said. Indeed the researchers found that having three or four healthy lifestyles compared to none generally was associated with better cardiovascular risk biomarkers such as lower serum cholesterol and homocysteine levels. Having at least one or two healthy lifestyle characteristics compared to none was also associated with better levels of some cardiovascular risk biomarkers. For more information visit www.oregonstate.edu. Tassajara Zen Mountain Center Guest Season Begins S an Francisco Zen Center is holding its annual public guest season at Tassajara Zen Mountain Center from April 28 to September 11 2016. As spring blooms Tassajara opens its gates to Zen and meditation seekers yoga lovers artisan foodies outdoor adventurists and people looking to unplug and experience a truly serene environment. Seven months of the year Tassajara is closed to the general public for private intensive Zen practice. Tassajara utilizes its eco-retreat center that was designed with the highest standards in green development by architect Helen Degenhardt (JSW D Architects) all retreats will be held in the retreat center. Tassajara offers a special opportunity for the general public to recharge relax and reconnect with themselves. Visitors are invited to soak in the hot springs wander along the trails savor Tassajara s lauded vegetarian cuisine lodge in beautiful accommodations participate in zazen (meditation) and enjoy the eclectic retreats offered by some of today s most celebrated teachers. Guests of Tassajara are encouraged to explore the variety of ways that Zen and other complementary practices can inform and enrich one s life. The Tassajara Guest Season Program Schedule 2016 offers disciplinary retreats in the following five specialty areas Body and Mind Engaging Earth Spiritual Practice Mindful Living and Creative Expression. Each Tassajara retreat offers the opportunity to restore and invigorate through engagement with Zen. Visitors join renowned teachers in practices they may already be familiar with and some that may be entirely new to them. Through meditations and teachings group discussions and creative exercises guests will discover the transformative potential of Zen practice and other traditions. Retreats ranging from two to seven days usually begin in the late afternoon and end before noon on the last day. Retreat schedules include plenty of free time to engage in meditation relax in the baths hike savor a cup of tea or simply just be. Tassajara offers retreat participants a dedi- cated practice space to study the body and mind under the guidance of expert leaders. Built using green materials the energy-efficient retreat hall is a manifestation of Tassajara s commitment to environmental sustainability and stewardship. It is a serene refuge allowing one to deepen their practice and connect with their own heart community and the surrounding natural environment. For more information visit www.sfzc.org tassajara. 12 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Emerson Ecologics Expands to New Western Distribution Center merson Ecologics LLC (Manchester NH) has announced its expansion and move into a new larger facility for western distribution in Riverside CA. At 50 000 square feet this new facility increases their operational capacity by more than 200 percent providing the space and capability to expand customer access to a greater product offering continuously improve delivery service levels and ultimately grow with their customers needs. We are pleased to be expanding our operations in Riverside CA. Only a short distance from our original location our new distribution center is a strong commitment to our California team as well as an important stride in our goal to provide industry leading product selection and customer service levels said Kevin Purcell chief operating officer at Emerson Ecologics. The Riverside community has been exceptionally welcoming and we look forward to our continued shared growth. An enthusiastic audience of local government officials and industry leaders joined the Emerson Ecologics team for a much anticipated ribbon cutting ceremony. Cindy Roth president and CEO of the Greater Riverside Chambers of Commerce greeted local officials including City of Riverside Mayor Representative Frank Arreola City of Perris Mayor Daryl Busch Riverside City Councilman Andy Melendrez California State Senator Richard Roth E Representative Tyler Madary City of Moreno Valley Councilman Jesse Molina and City of Morena Valley Mayor Pro Tem Jeffrey Giba as well as local business leaders including representatives from the Riverside Chambers of Commerce and the March Joint Powers Authority. After a presentation of Certificates of recognition Andy Greenwalt president and CEO of Emerson Ecologics recognized the tremendous efforts of the Emerson s distribution customer support medical education and technology team members during the move and thanked the local community for all of their support. As the industry-leading distribution partner Emerson Ecologics has had an operational presence in both the East and West for many years and the opening of this new West Coast facility follows their recent expansion and VAWD certification in their East Coast distribution center. Together these investments solidify their commitment to building a best-in-class supply chain to serve integrative health practitioners with ontime and accurate delivery of the highest quality professional vitamins supple- ments and personal care products. In other news Emerson Ecologics LLC recently announced that it is accepting applications for the 2016 Emerson Grant. The Emerson Grant Program is aimed at supporting the work of integrative health practitioners while also promoting integrative medicine in the United States. The Emerson Grant is a competitive discretionary award ranging from 500 to 10 000 with the 2016 Grant Program awards totaling up to 25 000. Projects may include legislative efforts public awareness campaigns or enhancements to education or clinical training but all projects are focused on expanding or improving integrative medicine. Each year we look forward to the launch of the Emerson Grant Program and the opportunity to help integrative organizations further their dream projects to increase the delivery and reach of integrative medicine to all those in need said Tina Beaudoin ND and senior medical educator at Emerson Ecologics. For more information visit www.emersonecologics.com. Patients Love Their Experience at Bastyr Center for Natural Health ewly released findings from the Washington Health Alliance show that for the third time in a row patients have an overwhelmingly positive experience when visiting Bastyr Center for Natural Health the Seattle teaching clinic of Bastyr University. Bastyr Center ranked in the top 10 in three of the survey s main categories scoring at or above the state s 90th percentile How Well Providers Communicate with Patients (7th) Helpful Courteous and Respectful N Office Staff (3rd) Patient s Overall Rating of the Provider (7th) The Washington Health Alliance survey Your Voice Matters Patient Experience with Primary Care Providers in Washington State is the only report of its kind and comes out every other year. In 2012 and 2014 when the survey focused on just the Puget Sound region Bastyr Center ranked in the top five both years. This year the survey was sent to 181 000 adults in 14 counties in Washington State covering 266 clin- ics. Once again Bastyr Center ranked among the top-tier medical facilities (16th overall out of 266.) To be recognized for this level of sustained excellence for the third straight report is extremely satisfying said Bastyr Center Chief Medical Officer Jamey Wallace ND. It is especially gratifying to see that even though the survey has expanded to include medical centers statewide Bastyr Center remains near the top. For more information visit www.bastyrcenter.org. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 13 HEALTH INDUSTRY NEWS FDA Approves Folic Acid to be Added to Masa Flour he U.S. Food and Drug Administration (FDA) has decided to allow manufacturers to fortify their corn masa foods with folic acid. Folic acid is a synthetic form of folate a B vitamin that helps prevent severe defects of the brain and spinal cord when consumed by women before and early [on] in pregnancy an NPR article reported. Pregnant women with folate deficiency have a higher risk of giving birth to infants affected with neural tube defects. NPR cited findings from the CDC (Centers for Disease Control) that since 1998 when the FDA required that breads pasta breakfast cereals and other grains made with enriched flour be fortified with folic acid the number of babies born in the U.S. with neural tube defects dropped about 35 percent (about 1 300 babies a year). The CDC urges all women who are capable of becoming pregnant to get at least 400 mcg of folic acid every day. The approval allows manufacturers to voluntarily add up to 0.7 milligrams of folic acid per pound of corn masa flour consistent with the levels of certain other enriched cereal grains the FDA said. The March of Dimes Foundation the American Academy of Pediatrics and others submitted a food additive petition in 2012 to request the extension of voluntary fortification to corn masa flour to increase the folic acid intake for U.S. women of childbearing T age who regularly consume products made from corn masa flour as a staple in their diet. Increased consumption of folic acid in enriched flour has been helpful in reducing the incidence of neural tube defects in the general population said Susan Mayne PhD director of the FDA s Center for Food Safety and Applied Nutrition. Our analysis shows that adding folic acid to corn masa flour will help increase the consumption of folic acid by women who consume this flour as a staple in their diet. Hispanic women are about 20 percent more likely than other women to have babies with those conditions [neural tube defects] and they continue to have far lower levels of folic acid intake either through diet or supplements NBC News shared. The FDA could approve the use of a food additive only after conducting a scientific safety review of the information provided in the petition to ensure that the additive is safe for the general population. With regard to folic acid the FDA evaluated the projected human dietary exposure toxicological data and other relevant information including whether folic acid remained stable in corn masa flour. The FDA worked with the petitioners throughout the review process to obtain data needed to address safety questions as expeditiously as possible. Based on that data the FDA concluded that the petitioned addition of folic acid to corn masa flour at a level not to exceed 0.7 milligrams of folic acid per pound of corn masa flour is safe. Exposure estimates from the FDA and the petitioners show that adding folic acid to corn masa flour could increase folic acid consumption in those who regularly consume products made from corn masa flour including many Latina women. The petitioners contend that increased consumption of folic acid will reduce the risk of births with neural tube defects among this group. The FDA s approval is not based on the possibility of this reduced risk but is instead based on a review of the safety of the proposed use of folic acid. Manufacturers were allowed to begin voluntary fortification of corn masa flour with folic acid on April 15. For more information visit www.fda.gov. THE GO TO RESOURCE FOR ALTERNATIVE & INTEGRATIVE HEALTHCARE PROFESSIONALS NP s Upcoming Issue Highlights June July 6 1 16 ad closing Healthy Aging & AANP Show Issue August 7 12 16 ad closing Quality Company Profiles Our 2016 Media Planner Is Available At NaturalPractitionerMag.com 2016-Media-Planner Contact One of Our Ad Specialists Today Russ Fields at 732-432-9600 ext. 102 e-Mail RussF VRMmedia.com Gary Pfaff at 732-432-9600 ext. 103 e-Mail GaryP VRMmedia.com 14 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com seroyal for info about this advertiser Mitigating pain and inflammation with the right tools can lead to a better quality of life. By Courtney Anaya CPT edness swelling and warmth illustrate inflammation which is often joined by immobility and pain. It s a normal response that s warranted with an injury or illness to protect the body from foreign invaders--a potential trigger for an infection. There is no statistical information present regarding general inflammation in America but it is evident that with the increase in various diseases and illnesses that inflammation is current. Pain that has manifested from inflammation can be chronic according to the Institute of Medicine as many as 100 million Americans suffer from it. When the body experiences inflammation such as when tissues are being targeted by bacteria trauma or heat the injured tissues release chemicals these chemicals are histamine bradykinin and serotonin and they re responsible for feeding the damaged area with blood. The blood serves as a protective agent against R the foreign compound to prevent further damage. Histamine bradykinin and serotonin also attract white blood cells called phagocytes to consume the bad bacteria and damaged cells--a process which is known as phagocytosis. The end result of all this swelling. Swelling can be painful and as mentioned before it can lead to chronic pain. But it s important to note the differences between acute and chronic inflammation. For starters acute inflammation also called systemic inflammation is associated with minor injuries or illnesses like a sprained ankle or sore throat ultimately lasting a few days. Chronic inflammation stems from wear and tear conditions like rheumatoid arthritis Crohn s disease and inflammatory bowl disease (IBD). Chronic inflammation is what causes chronic pain. The factors causing the chronic issues can be blamed on a poor diet lack of exercise stress weight gain poor hygiene alcohol intake and smoking. The poor lifestyle and environmental factors are liable as to how the body perceives an internal threat because an inflammatory response may not always be needed. But when it does occur there s no destination for the throng of white blood cells--ultimately leading to the attack of other tissues and organs that are healthy. To check if a condition is chronic a doctor may order a C-reactive protein (CRP) test to check for inflammation which is a simple blood test. The liver creates CRP when there s inflammation indicating a high CRP level during the test. Unfortunately the test shows that inflammation is present but not the location. Having high levels of CRP have been associated with coronary artery disease a reason why doctors order the test to determine if a person is at risk for having a heart attack or stroke. A CRP test is also used to help monitor pelvic inflammatory 16 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 disease IBD arthritis and autoimmune disease like Crohn s disease. A review published by the journal The Anti-inflammatory Diet With anything diet can play the role as medicine to alleviate symptoms especially pertaining to pain and inflammation. The anti-inflammatory diet has been well popularized as a mechanism to fight inflammation. Foods high in antioxidants monounsaturated fats omega-3 fatty acids and vitamins are emphasized in the diet. A fine example of the anti-inflammatory diet is the Mediterranean diet which also focuses on the same types of food. The healthy fat category should contain foods like salmon tuna flax seed olive oil and nuts. A study published by the Journal of Nutritional Biochemistry discussed that consuming fats like those from the Mediterranean diet--focusing on monounsaturated fats--reduced the inflammation process. This was compared to consuming a high saturated fat diet. In regards to nuts Dr. Shailinder Sodhi a Natural Practitioner advisory board member said Studies have shown that eating 1.4 grams of nuts daily is associated with a 49 percent reduction in risk of death from chronic inflammation-related diseases. As for fruits and vegetables it s recommended to go for the dark leafy greens or anything that has true color. These types of vegetables contain powerful antioxidants. A review published by the journal New Horizons supports that antioxidants do reduce inflammatory symptoms related to joint disease and stomach issues. Coupling antioxidant-rich food with healthy fats will help to further emphasize the diet s anti-inflammatory properties. Lean proteins such as turkey and chicken should also be added to the mix. Lastly incorporating probiotic rich foods such as fermented vegetables and dairy products will help to strengthen the gut s integrity. The reason inflammation is the immune system s way of saying there s something wrong and close to 70 percent of the immune system resides in the gut. When there are excessive-gram negative bacteria present within the gut inflammation can occur. That s why it s important to consume probiotic-rich food to balance out the gut s microflora. Additionally certain probiotics have been seen to increase the production of proinflammatory cytokines these substances are short chain fatty acids that can lower inflammatory markers like CRP throughout the body. Proving this a study done by Nutrition had a group of rheumatoid arthritis patients supplement with a probiotic. The results the markers of inflam- New Horizons supports that antioxidants do reduce inflammatory symptoms related to joint disease and stomach issues. Coupling antioxidant-rich food with healthy fats will help to further emphasize the diet s anti-inflammatory properties. mation were drastically lower. Cura Power While a healthy diet is adhered the right supplementation plan can be even more beneficial. That s where EuroPharma Inc. steps in to help alleviate any painful issues pertaining to inflammation. Located in Green Bay WI EuroPharma has been focused on introducing European-tested medicines and proprietary formulas to the American consumer. Cheryl Myers chief of scientific affairs and education at EuroPharma said The owner of our company Terry Lemerond was a pioneer in the field of natural products for practitioners. In the past he launched PhytoPharmica which merged into Integrative Theraputics (ITI) after the sale of his companies in 2000. EuroMedica is his newest company launched in 2010. A trend that the company has seen pertaining to inflammation is self-directed care. Myers said Consumers are less willing to accept health directions and pronouncements without having significant evidence. They don t want to know just what to take--they want to know why they should take it. That trend has been a driving force for EuroPharma in creating formulas that can answer the why specifically formulas that involve curcumin and boswellia. Myers explained There is a type of inflammation most commonly associated with lung and gut disorders called 5lipoxygenase (5-LOX) and while curcumin does modulate this pathway boswellia is even more powerful. Therefore for many inflammatory diseases curcumin is the best choice but for those with high levels of 5-LOX activation I prefer a combination of curcumin and boswellia. For inflammation and pain purposes the company offers ArthoMed BosPro Curaphen Professional Pain Formula Curaphen Extra Strength Professional Pain Formula CuraPro EurOmega-3 and Traumaplant Comfrey Cream. ArthoMed combines studied BCM-95 Curcumin with BosPure boswellia along with standardized devil s claw and Indian gooseberry to support joint flexibility lubrication and cushioning. It s counterpart BosPro contains a high potency boswellia that can reduce pro-inflammatory compounds called betaboswellic acids. Curaphen Professional Pain Formula is made with BCM-95 Curcumin BosPure boswellia and DLPA to target pain relief in multiple areas the extra strength version is simply made with higher levels of each to better target pain relief. The last of the curcumin bunch is CuraPro which is also made with BCM-95 curcumin and turmeric essential oils to target inflammation. And of course there s an omega-3 supplement--EurOmega-3-- to help combat inflammation. The formula is comprised of EPA and DHA without the fish oil and they are naturally bound to phospholipids for more efficiency. Last but not least is Traumaplant Comfrey Cream a cream that s proven free of pyrrolizidine alkaloids. There are 20 published studies on this product in both children and adults. Joining the curcumin trend is Ayush Herbs a Washington-based company that offers ayuverdic herbal products that are based off of traditional ayuverdic combinations by containing herbs that have been grown in a Himalayan environment. The company offers CoCurcumin. Dr. Sodhi explained that the product is extracted from the infamous Indian spice turmeric and curcumin is the single most important player in promoting a healthy inflammatory and metabolic response. This specific formulation is MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 17 infused with medium chain triglycerides from coconut milk to allow for bioavailability of curcumin since curcumin is highly lipophilic. Trikatu is a traditional ayuverdic combination for digestive health as it contains piperine from black pepper and has been seen shown to enhance turmeric absorption. The addition of CoQ10 provides additional cardiovascular and inflammatory support. CustomVite now offers more than 130 nutrients including vitamins minerals essential fatty acids enzymes probiotics phytonutrients botanicals amino acids and more. Each formula is tailored to a patient s individualized needs--no two formulations are alike. Requirements are identified by Health Improvement Assessment questionnaire and current laboratory analysis (blood urine hair stool micronutrient and DNA samples) as well as utilizing some recommended formulations such as condition-specific protocols to provide a broad spectrum of support for an individual s nutritional needs. Patient s joints are another inflammationhitting area that can cause not only pain but also immobilization. The condition-specific protocol library is a comprehensive library that contains nutrition support to address health concerns such as inflammation. These protocols are continuously updated with the latest research. Supplements within a protocol can be changed depending on the patient s needs they re simply recommendations. To get started health care practitioners can have their patients complete CustomVite s Health Improvement Assessment and submit current labs to determine the proper supplement regimen. Natasha Paroutis CustomVite s nutrition director said We also offer our customers easy-to-swallow gelatin or vegetarian capsules and soft gels. We package our supplements into convenient daily dose packets so it s very easy for each patient to consume their vitamins. We also offer our formulations in powder if a patient is unable to swallow capsules. It s evident that the goal of CustomVite is to customize a patient s health journey. As for the inflammation support protocol specific ingredients such as mixed carotenoids vitamins B1 B2 B3 B4 B5 B6 and B12 magnesium l-cysteine zinc mixed tocopherols turmeric root fish oil bromelain MSM bilberry and glucosamine are included. Fish oil and bromelain may help to reduce inflamma- Extra Joint Support Patient s joints are another inflammationhitting area that can cause not only pain but also immobilization. Enter Alchem USA an herbal extract manufacturer that s based in Minnesota offering FlexiQule. This product targets joint stiffness and pain and is comprised of Boswellia PhytoExtract. Several studies have been done showing its effectiveness. The Minerva Gastroenterologica e Dietologica journal published a study where a group of patients took FlexiQule for osteoarthritis and results indicated the group had less pain and were able to walk better. Another study was published by the same journal where patients had osteoarthritis within the knee and FlexiQule was taken. Results were also the same. And lastly a third study was published in the same journal where osteoarthritis targeted the hands FlexiQule was also taken. The results also indicated that FlexiQule improved pain and movement. tory issues whereas glucosamine helps to preserve cartilage. Also bromelain and turmeric are natural COX-2 inhibitors which help to block the enzyme that produces prostaglandins--a hormone that s associated with pain and inflammation. Paroutis explained There are common medications that are COX-2 inhibitors but those can have serious side effects and can affect blood pressure. Therefore many have opted for the more natural approach and have chosen herbal supplements that have natural COX-2 inhibitors. As for how CustomVite stands apart from other anti-inflammatory aides on the market the company offers a 25 percent commission to the practitioner on each order placed and all raw material ingredients are purchased in the USA and third-party tested for potency and purity. Also as mentioned before CustomVite adapts to a patient s individual needs and patients don t have to purchase multiple vitamin bottles thanks to the daily dose packets. Practitioners can find more information on the CustomVite program at www.customvitepro.com. References Belcaro G. Dugall M. Ledda A. Pellegrini L. & Ippolito E. (2015 October 22). Management of osteoarthritis (OA) with the pharma-standard supplement FlexiQule (Boswellia) A 12-week registry. Retrieved from www.ncbi.nlm.nih.gov pubmed 26492586. Jones D. S. (2010). Textbook of Functional Medicine. Gig Harbor WA. Institute for Functional Medicine. Follow The Rules Established in 1999 New Jersey-based CustomVite received its start from Sam Abraham a Harvard Business School graduate who had found himself staring at the wall of supplements in his local health food store. Abraham was curious to understand if the business model used by Dell Computers--manufacturing to the precise specifications of individual customers-- could be applied to the supplement industry. From that one thought Abraham was able to develop a program that offers consumers dietary supplements based on their true individual needs. With that all said A CRP test is used to check for inflammation in the body. Adding probiotic-rich foods have been seen to reduce inflammation. One hundred million Americans suffer from chronic pain. 1.4 grams of nuts can reduce death from inflammation by 49 percent. Boswellia can be more powerful than curcumin to target pain and inflammation. Healthy Take Aways FOR MORE INFORMATION Alchem USA (952) 933-3822 www.alcheminternational.com Ayush Herbs (800) 925-1371 www.ayush.com CustomVite (800) 379-9979 www.customvite.com EuroPharma Inc. (866) 598-5487 www.europharmausa.com 18 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com euromedica for info about this advertiser By Lisa Schofield W omen don t actually feel their hormones surging or retreating but they sure do feel the symptoms. For some those symptoms may be simply attributed to stress over exercise or a meal that is disagreeable. Symptoms of hormonal fluctuations at any stage in a woman s life vary widely and unlike in conventional medicine there isn t or should not be a one size fits all supplement regimen. For example one 30-year-old woman s pre-menstrual symtpoms may be completely different than those of another 30-year-old as well as intensities. Some women experience debilitating uterine cramps while others expereience no cramps but intense headaches. And the suite of symptoms during childbearing years often changes in the same woman. New York-based practitioner and educator Amber Lynn Vitale BA CN LMT noted that in childbearing years symptoms of PMS (premenstrual syndrome) that are not so obvious can include acne or other skin conditions such as rosacea. Also less commonly associated symptoms can include heightened anxiety and depression. These symptoms she said reflect an inability to process both endogenous and exogenous toxins. Endogenous toxins are produced normally as byproducts through cellular function as well as digestion of food. But exogenous overload (overly processed nutrient-depleted foods birth control pills and other medications and environmental endocrine disruptors) can disrupt the delicate normal balance. In ayurveda Vitale pointed out the reproductive system is the last tissue to be nourished. If the other tissues have a high demand due to stressful factors the reproductive system misses out. This can be seen all across the animal kingdom--stressed animals do not reproduce. Or if they do mis- takes or defects happen. She added that a younger woman s microbiome is affected by all of endogenous and exogenous toxins. An imbalanced microbiome is shifted in the favor of hosting pathogenic instead of beneficial microbes and pathogenic microbes are not engaged in activities that create beneficial hormones or promote positive hormonal conversions and detoxification. According to women s health expert Sara Gottfried MD New York Times bestselling author of The Hormone Reset Diet and The Hormone Cure most younger women feel hormonally on track as they experience a predictable cycle characterized by normal estrogen and progesterone levels. Progesterone is key to women s ability to roll with the punches. In the brain progesterone makes allopregnanolone which interacts with GABA and serotonin for a foursome that truly soothes the female brain she 20 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 described. A common hormone imbalance in childbearing-aged women said Dr. Gottfried is premenstrual syndrome (PMS) which she stated may be an issue of progesterone resistance according to latest research. Production of many hormones (estrogen progesterone and testosterone) begins to decline when in a woman s latter 20s or 30s--and often in the case of polycystic ovary syndrome testosterone climbs. Based on the latest figures excess androgens in PCOS is present in 30 percent of women of childbearing age cited Dr. Gottfried. With PCOS we also commonly see insulin and leptin resistance. Holly Lucille ND RN author of several books including Creating and Maintaining Balance A Women s Guide to Safe Natural Hormone Health said she sees women dealing with uterine fibroids endometriosis and ovarian cysts as well as for PMS. Dr. Lucille also blames the overarching influence of our chemically dependent society. After all we are the first generations to be exposed in a way which we never have seen before and it is making a difference with our bodies especially the endocrine system she said. There is a range of nutritional protocols our experts would suggest. For women concerned about reproductive balance Vitale likes herbal adaptogens. That said she noted most herbal and nutritional therapies employed may not necessarily address the fundamental hormonal imbalance problems. In fact as we discovered through early microbiome research and applied to functional medicine more than a decade ago it is not beneficial to treat the body with hormones or hormone-balancing nutraceuticals without first balancing the gastrointestinal microbiota she stated. Today many women are dealing with high levels of toxins that may render herbal tonics and adaptogens somewhat powerless. In practice Vitale offered women who may have heavy toxic exposures should first be recommended to engage in cleansing then restore nutrients and gut flora before implementing a serious adaptogen protocol. Adaptogenic herbs like ashwagandha often are contraindicated in traditional herbal pharmacopeia during states of high toxicity. After cleaning the diet from sugars flours and processed foods that selectively nourish pathogenic bacteria suggest implementing a cleansing protocol that supports all organs in detoxification blood spleen lymph lungs skin urine kidneys bile liver and gastrointestinal tract Vitale recommended. After your patient client reveals she is experiencing higher levels of waste moving out of all elimination pathways probiotic and pre-biotic therapy can include researched strains that have demonstrated positive health benefits for females like L. rhamnosus and L. reuteri NCFM L. acidophilus L. helveticus B. longum. Providing prebiotic fibers from organic plants lowers the toxic load in a myriad of overlapping ways and is crucial to gastrointestinal health that leads to hormonal health Vitale explained. From this point on any herbal or nutraceutical protocol implemented will be much more effective. And many of the hormonal problems like PMS skin issues and mood fluctuations will have already improved before using any other therapies. Dr. Lucille completely agrees with this protocol and the reason behind it noting that from a nutritional and lifestyle perspective I think it is about reducing exposure and encouraging healthy hormonal balance and estrogen detoxification. Because estrogen is metabolized through the liver which is also burdened with processing xenoestrogens and exogenous estrogens (oral contraceptives and hormone therapy) proper detoxification is important. Eating a plant-strong nutrientdense and organic diet is one of my strongest recommendations. Also animal proteins should be as clean as possible and free of additives and growth hormones. Supplements Dr. Lucille likes to recommend to women to encourage healthy estrogen metabolism include DIM flax seeds trimethyl-glycine glutathione and liver support such as milk thistle. For women who live high-stress lifestyles progesterone is often called upon as cortisol if needed leading to a major imbalance in the progesterone estrogen ratio. In this case Dr. Lucille said she likes to recommend adrenal support and progesterone-inducing herbs such as vitex. From a supplement formulator s perspective Leonid Ber MD science and technology manager Protocol for Life Balance Illinois maker of Herbal Menopause (EstroG-100) Lifestyle Changes to Recommend W omen s health expert Sara Gottfried MD New York Times bestselling author of The Hormone Reset Diet and The Hormone Cure offers a few key interventions so you don t become a hormonal wreck Cut out caffeine. It affects estrogen cortisol thyroid and testosterone adversely. Drink less alcohol. Alcohol raises cortisol robs you of deep sleep and lowers metabolism by more than 70 percent. Dance differently with stress. Develop a more playful attitude laugh more roll with the punches hang out with girlfriends take a super hot detox bath with epsom salt. These buffer you when you re a highly sensitive person also known as a stress case. Master your sleep. Only 6 percent of the population does well on less than eight hours of sleep. It keeps cortisol in check which prevents the muffin top. Get your omega-3s on. These healthy fats have been shown to lower cortisol and make you lean. Burst training is better than cardio--it raises your growth hormone and melts the muffin top. To combat symptoms of perimenopause Eat foods rich in vitamin C (papaya bell peppers citrus dark leafy greens) to increase progesterone levels naturally or take a supplement of 750 mg daily. Reduce caffeine consumption and try yoga to relieve mood swings difficulty sleeping and lack of energy. Many women notice that the same tricks to lose weight no longer work--and that may be because your thyroid is slowing down or your testosterone fell off a cliff. Be sure to get your levels checked with your health care professional. To counteract weight gain cut out sugar from your diet and make sleep a priority which will put your growth hormone production back on track. To naturally reset your estrogen levels Eat a pound of vegetables per day. The fiber from the vegetables will help excrete estrogen so it doesn t keep circulating in your body like bad karma. Aim for 35-45 grams of fiber per day for women and 4050 grams per day for men but slowly increase in 5-gram increments each day to get to the goal without gas or bloating Reduce your alcohol levels. We know that alcohol raises your estrogen levels and can disrupt your liver function. Even as little as three servings per week can raise your risk of breast cancer. Avoid xenoestrogens. I recommend that you use low or no VOC materials and paints and always stick to organic textiles. Ensure appropriate ventilation. Look for food and cosmetic items that are natural BPA and phthalate free. Eat less meat from conventionally raised animals. Meat consumption raises your estrogen and can aggravate estrogen dominance. Indeed women with endometriosis consume more red meat and eat less fish and vegetables. Overall more meat consumption is associated with less fiber consumption which raises bad estrogens and grows the wrong bacteria in your microbiome. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 21 explained We realize that women and their physicians often want to limit their exposure to phytoestrogens. This aspect of the formula is critically important to those with higher risk of estrogen-associated conditions (i.e. family history of breast tumors). The task of creating efficacious but completely estrogenfree product is challenging but not unattainable he commented. Also in a woman s latter childbearing years anytime between age 35 and 50 symptoms emerge that may be confused with PMS but signal peri-menopause the years of hormonal upheaval prior to the final menses--menopause itself is typically determined to be one full year after that event according to Dr. Gottfried. Differentiating symptoms from PMS include trouble sleeping insomnia night sweats decreased energy difficulty in maintaining weight or gaining stubborn pounds around the midsection increased events of mood swings and irritability not around the menses and unpredictable periods. She explained that during this time Other hormones also start to fade or deregulate--a peri-menopausal woman s ovaries thyroid and adrenals start to work against her not for her. And to confuse matters even further the brain becomes less responsive to the hormones that her body does still produce. There are two phases to perimenopause phase 1 is when progesterone drops and estrogen fluctuates wildly (overall higher in level) because the feedback loops don t work and phase 2 is when both estrogen and progesterone drop. She recommends the following supplements Cortisol Manager (at night) which contains ashwagandha and phosphatidylserine up to 400 IU vitamin E to mildly reduce mood swings hot flashes and vaginal dryness magnesium and or red ginseng to reduce fatigue and hot flashes maca to battle insomnia and mood cognitive issues and to improve BMI (body mass index) and bone density and Pueraria lobata a traditional Chinese herbal remedy for overall symptom support. Protocol for Life Balance recently launched its verified phytoestrogen-free Herbal Menopause (EstroG-100) which contains a clinically validated combination of Phlomis umbrosa Cynanchum wilfordii and Angelica gigas Nakai extracts which according to Dr. Ber individually and as a combination exhibit no adhesion to estrogen receptors in vivo. Additionally when it was used in the clinical trial there was no change in the FSH (follicular stimulating hormone) and estradiol levels among the women consuming both the supplement and placebo demonstrating its phytoestrogen-free nature. As such the product offers [an] excellent alternative to soy isoflavones and black cohosh he said. Estrogen stimulates breast cells to grow while progesterone prevents cysts from developing in painful breasts. --Sara Gottfried MD According to Dr. Ber Herbal Menopause (EstroG-100) was shown to alleviate symptoms of menopause and peri-menopause such as hot flashes night sweats nervousness occasional sleeplessness and difficulty in maintaining positive mood. In fact 50 percent of women taking the supplement experienced improvement in at least one menopausal symptom within seven days of use with 75 percent experiencing improvement in at least one menopausal symptom within 14 days he reported. The company also offers the topical product Liposomal Progesterone Cream available in unscented and lavender each delivering 20 mg of natural progesterone (USP) per pump without artificial colors fragrances or parabens. It contains complementary herbs such as angelica chamomile and lemongrass. Although not verified as a phytoestrogenfree product Progesterone Liposomal Cream is typically used by women in post menopause with significant rate of success Dr. Ber said. A common occurrence during perimenopause and post-menopause is the development of breast cysts which are benign. According to Dr. Gottfried cyst development is typically spurred by hormonal imbalances. Estrogen stimulates breast cells to grow while progesterone prevents cysts from developing in painful breasts. Because estrogen and progesterone have opposing yet interdependent effects balance between them is crucial. The potential for breast cysts increases during perimenopause due to higher estrogen levels and lower progesterone levels. Balancing your estrogen levels can help to prevent the occurrence of breast cysts. Although PMS and peri-menopausal symptoms are certainly both uncomfortable and disruptive reasonably healthy women may be led through practitioner knowledge and supplementation to dramatically reduce severity and frequency of symptoms greatly increasing overall quality of life. No two women experience the same symptoms or intensity of symptoms caused by hormonal fluctuations. Look for less obvious PMS symptoms such as acne rosacea as well as anxiety and depression as these often may be caused by intense hormonal swings. During childbearing years acute stress may hamper fertility in ayurveda the belief is that the reproductive system is the last to be nourished. The female microbiome when overly toxic may heavily affect the hormonal balance causing more intense symptoms of PMS and perimenopause. Detoxification followed by replenishment of healthy bacteria are recommended first steps along with a chemically conscientious lifestyle reducing exposure to xenoestrogens and pharmaceutical hormones. More women are questioning the effect of phytoestrogens and how they impact their hormonal health. Breast cyst development often stems from higher estrogen and lower progesterone levels. Healthy Take Aways FOR MORE INFORMATION Sara Gottfried MD (888) 893-6586 www.saragottfriedmd.com Holly Lucille ND RN (323) 658-9151 www.drhollylucille.com Protocol For Life (630) 545-9098 www.protocolforlife.com Amber Lynn Vitale (865) 936-1545 www.amberlynnvitale.com 22 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Branch Out and Join VRM Media s FAMILY OF PUBLICATIONS NaturalPractitionerMag.com VitaminRetailer.com NIEmagazine.com FitnessTrainerMag.com Contact One of Our Ad Specialists Today Russ Fields at 732-432-9600 ext. 102 e-Mail RussF VRMmedia.com Gary Pfaff at 732-432-9600 ext. 103 e-Mail GaryP VRMmedia.com 2016 CAMInnovations standing of the research and history behind the products available to practitioners and their patients and manufacturers wanting to offer the science that backs the effectiveness of their products. We have featured a similar section annually in Natural Practitioner s sister publication Nutrition Industry Executive magazine since 2002 which was designed to help manufacturers gain a better understanding of the ingredients and services available that can make their products stand out. Companies and associations have responded to this opportunity with background information about the health concerns their products are intended to address histories of the nutrients behind their products and details of research carried out. In order to bridge the gap between interested practitioners and these companies we ve also provided company addresses phone numbers and website addresses to make obtaining additional information easier. 24 NATURAL PRACTITIONER T his special section of Natural Practitioner comes in response to the desire for a greater under- Following is an index of companies participating in the 2016 Natural Practitioner CAM Innovations section Albion Minerals ..............................................................25 America s Finest Inc. ......................................................26 Daiwa Health Development Inc. ..................................27 DaVinci Laboratories of Vermont ................................28 EuroMedica ....................................................................29 Kyowa Hakko USA ........................................................30 MitoQ Limited ................................................................31 Natural Partners Inc. ....................................................32 Seroyal ............................................................................33 WWW.NATURALPRACTITIONERMAG.COM MAY 2016 2016 CAMInnovations Albion Minerals 101 N. Main St. Clearfield UT 84015 Phone (801) 773-4631 (800) 453-2406 (U.S. & Canada) Fax (801) 773-4633 Email info albionminerals.com Website www.albionminerals.com Magnesium Innovations in Clinical Practice--Form Matters The Critical Role of Magnesium The human body cannot function properly without minerals. While all minerals are important evidence continues to unfold regarding the critical role magnesium plays. Magnesium is a cofactor in more than 300 enzyme systems and regulates approximately 80 percent of biochemical reactions.1 Magnesium is the fourth most abundant mineral in the human body involved in many critical functions including Normal bone growth Maintenance of heart rhythm and blood pressure Formation and contraction of muscle Energy production and formation of ATP Nerve conduction Maintenance of mood and cognitive function A system of major importance that relies heavily on magnesium is that of cell proliferation. In this system magnesium has been shown to have direct influence on cell cycling protein synthesis and growth factor response. Protein synthesis is highly dependent on intracellular magnesium concentrations. Increasing the magnesium content amplifies protein synthesis.2 of a magnesium supplement that causes laxation is likely worse than not taking the supplement at all. and 600 mg of elemental magnesium there were no significant differences in tolerability and gastrointestinal distress as compared to a maltodextrin placebo.7 These findings corroborate earlier research in subjects with ileal resections.8 Mineral absorption may be affected by a number of factors including Mineral competition Cellulose Excess dietary fats Incorrect gut pH Precipitating anions Phosphates phytates Oxalates Albion s Magnesium Bisglycinate Chelate is far less affected by the common inhibitors of mineral absorption. It has the dual advantage of being both highly bioavailable and highly tolerated. It provides an ideal solution to provide dietary supplementation to support adequate magnesium status. What Form of Magnesium Should Health Care Practitioners Recommend It is important to look at the research and evidence regarding the bioavailability of magnesium. There are many different forms of the mineral. Inorganic magnesium forms include Oxides Sulfates Carbonates Chlorides While organic forms include Organic acid salts (citrates malates) Complexes Chelates So which form is best Organic mineral amino acid chelates (Figure 1) have been scientifically proven to be more easily absorbed into the human body. A simple description of a mineral chelate is a metal that is attached to an anion at two or more separate sites--like a claw. To form a chelate a ligand must have two points of attachment to the metal and form a ring. Chele is Greek for lobster claw and describes how the ligand is bound. The claw restricts the cation from entering into other chemical reactions for example with phytates. At the 2016 Experimental Biology meetings research was presented that demonstrated that Albion Magnesium Bisglycinate was highly absorbed in vitro using a Caco-2 human intestinal cell model.5 In this study it was found that Albion Magnesium Bisglycinate had greater absorption than magnesium oxide and magnesium citrate. Additional research suggests that Albion Magnesium Bisglycinate combined with magnesium oxide may have some benefits6 without compromising bioavailability.5 Magnesium has a reputation for causing gastrointestinal distress and laxation when taken in high doses. Thus it is important that a highly bioavailable source or magnesium be well tolerated. In research presented at the 2016 Society of Toxicology meetings it was shown that in healthy adults Albion Magnesium Bisglycinate at dosages of 300 450 Mineral Research and Innovation Albion Minerals has proven that its amino acid chelates are effective in more than 200 studies and 70 human trials. Albion has also been granted more than 100 patents in the field of mineral nutrition worldwide. Magnesium Deficiency and Potential Risks The Daily Recommended Intake of magnesium for adults is 310-420 mg. It has been estimated that approximately 60 percent of individuals in the U.S. may not have adequate dietary intake.3 There are a number of things that may contribute to magnesium deficiency including diet lifestyle medications and diseases disorders. Although magnesium is ubiquitous in the diet there is no major food that provides extremely high amounts and only about 30-40 percent of dietary magnesium is actually absorbed (depending on intake).1 It has been suggested that the inadequate dietary intake of magnesium may be a risk factor or correlated to several chronic diseases including sudden cardiac death 4 Alzheimer s disease 1 diabetes metabolic syndrome 1 obesity3 and strokes 1 to name a few. For these reasons dietary supplementation of magnesium may be beneficial. Currently the primary clinical use of magnesium is for treating constipation. However repeated use Figure 1 Mineral Acid Chelates are complex structures where the mineral is bound by amino acids to form a heterocyclic ring. References 1 Volpe SL. Adv. Nutr. 4 378S 383S 2013. 2 Proc Natl Acad Sci USA 76 3917-3921 1979. 3 Nielson FH. Nutr Rev 68 333-340 2010. 4 Chiuve SE et al. Am J Clin Nutr 93(2) 253-260 2011. 5 Hartle J et al. FASEB J 30(No. 1 Supplement) 128.6 2016 in press. 6 www.albionminerals.com human-nutrition magnesium-white-paper Accessed April 8 2016. 7 Ashmead S et al. The Toxicologist Supplement to Toxicological Sciences 150(1) Abstract 2457 2016. 8 Schuette SA. J Perenteral Enteral Nutr. 18 430435 1994. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 25 2016 CAMInnovations America s Finest Inc. (AFI) 20 Lake Dr. East Windsor NJ 08520 Phone (732) 985-9899 Email info afisupplements.com Website www.afisupplements.com AKBBA MAX C hronic inflammation is the root cause of most degenerative diseases. It was the old school of thought that believed that inflammation represents the healing process which may be true if inflammation is controlled. However when this inflammation becomes chronic it manifests itself as a disease condition. The understanding about inflammation is no longer limited to studies carried out at the tissue levels but is well researched at the cellular level. Studies and experiments have gone way deeper into the nuclear level. Cellsignaling molecules have been identified which stimulate the genes that induce the expression of the COX enzyme which in turn induce inflammation. Present day lifestyle which involves a lot of stress minimal physical activity and unhealthy eating patterns has made chronic inflammation associated disorders a very common problem prevailing in almost every part of the world. Stress or injury to any tissue leads to its damage due to the release of pro-inflammatory mediators which is required for the healing process. One of the key enzymes that are responsible for the production of inflammatory hormone-like compounds called prostaglandins and cytokines is Cyclooxygenase-2 (COX-2). While triggering this mechanism is essential for the body to fight infections and heal injuries the overproduction of COX-2 (or other pro-inflammatory mediators) results in chronic inflammation and pain. This is a vicious cycle which requires the intervention of anti-inflammatories to prevent further tissue damage that could lead to severe osteoarthritic conditions. The major use of Boswellia serrata in contemporary medicine is as an anti-inflammatory agent. The anti-inflammatory properties of the gum resin attributes to the presence of boswellic acids. They are reported to be non-competitive inhibitors of 5-lipoxygenase enzyme with AKBBA (Acetyl-11keto--boswellic acid ) being the most potent inhibitor. Boswellic acids also block human leukocyte elastase (HLE) activity. This dual inhibition of HLE and 5Lipoxygenase enzyme is unique to boswellic acids.1 AKBBA one of the identified and characterized boswellic acids is reported to be active against a large number of inflammatory diseases including cancer arthritis chronic colitis ulcerative colitis Crohn s disease and bronchial asthma. AFI s AKBBA MAX is enriched to contain 90 percent AKBBA and finds potential use in the management of several inflammatory conditions. Boswellia serrata has antiinflammatory action much like conventional non steroidal antiinflammatory drugs. Long term usage of boswellia does not lead to irritation or ulceration of stomach hence safer than NSAIDs (nonsteroidal anti-inflammatory drugs). In a study involving 175 patients clinical effectiveness of boswellic acids in the treatment of arthritis a severe inflammatory condition of the joints was found to be significantly good.2 In another study patients were assessed by Western Ontario and McMaster Universities Osteoarthritis index (WOMAC) scale at monthly intervals and at the end of the study and found to have significant positive influence. The result was also observed at the end of the seventh month thus evaluating the residual effect of treatment.3 Ulcerative colitis is a form of inflammatory bowel disease (IBD). It is a disease of the intestine specifically the large intestine or colon that includes characteristic ulcers or open sores in the colon. In a pre-clinical trial Anthoni C. et al (2006) reported that AKKBA confers protection in experimental murine colitis induced by dextran sodium sulfate (DSS).4 Treatment with AKBBA significantly blunted disease activity as assessed both grossly and by histology. Results of a clinical study on Boswellia serrata extract in the treatment of bronchial asthma revealed that 70 percent of patients showed improvement including disappearance of physical symptoms and signs such as dyspnoea bronchi number of asthma attacks decrease in eosinophilic count and ESR.5 AKBBA MAX thus finds important applications in various inflammatory conditions. Refernces 1 Shah B A Qazi GN and Subhash Chandra. Boswellic acids a group of medicinally important compounds. Nat. Prod. Rep. 2009 26 72-89. 2 Gupta VN Yadav DS Jain MP and Atal CK (1987) Chemistry and Pharmacology of the gum resin of B. serrata. Ind. Drugs 24(5) 221-231. 3 Sonteke et al (2007) Open randomized controlled clinical trial of Boswellia serrata extract as compared to valdecoxib in osteoarthritis of knee. Indian J. Pharmacol. 39 27-.29. 4 Anthoni C Laukoetter MG Rijcken E Vowinkel T Mennigen R M ller S Senninger N Russell J Jauch J Bergmann J Granger DN and Krieglstein CF (2006) Mechanisms underlying the anti-inflammatory actions of boswellic acid derivatives in experimental colitis. Am. J. Physiol. Gastrointest. Liver Physiol. 290 11311137. 5 Gupta V et. al (1998) Effect of Boswellia serrata gum resin in patient with bronchial asthma Results of a double blind placebo controlled 6 week clinical study Eur. J. Med. Res. 3(11) 511-4. 26 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 2016 CAMInnovations Daiwa Health Development Inc. 1411 W. 190th St. Ste. 375 Gardena CA 90248 Phone (877) 4DHDMED (434-3633) Email info dhdmed.com Website www.dhdmed.com Summary of BRM-4 a Natural Immune Modulator RM-4 is a dietary supplement produced by culturing rice bran with shiitake mushroom mycelia. It is in widespread use internationally for its immune-modulating and other therapeutic properties. BRM-4 supports the immune by both strengthening and modulating immune system activity. BRM-4 increases the activity of the body s white blood cells--particularly T and B cells but especially the all-important Natural Killer (NK) cell function. When NK activity slows down recognition of unhealthy infected or malignant cells is also diminished. This essential task of the immune system can result in buildup of toxic debris of unhealthy or infected dysfunctional or senile cells. This accumulation can cause damage to tissues and activate a chronic inflammatory response. There is also evidence that NK cell clearance of tumor cells following surgery is vital in preventing postoperative metastases. Surgery reduces NK cell total numbers in the spleen and affects their migration as well as their activity. In one study a group of 20 healthy adult men and women were given a daily dose BRM-4 for 60 days. NK cell activity rose by approximately 35 percent in the first week. There have also been good results as an adjunct treatment in cancer. In a three-year randomized comparison trial patients with hepatocellular carcinoma (a type of liver cancer) who took BRM-4 had a reduced recurrence rate of the cancer (31.6 percent BRM-4 group versus 46.7 percent in controls). The BRM-4 patients also lived longer. There have also been favorable results with other types of cancer such as multiple myeloma lymphoma ovarian prostate and breast cancer. Most people are aware of the devastating effects of cancer chemotherapy. If doctors were able to use a substance to sensitize cancer cells to chemotherapy it could be possible to lower the doses of these extremely toxic substances. BRM-4 also mitigates some of the toxic effects of chemotherapy drugs and radiation treatment. Impaired immune function can also cause or aggravate infec- B Most people are aware of the devastating effects of cancer chemotherapy. If doctors were able to use a substance to sensitize cancer cells to chemotherapy it could be possible to lower the doses of these extremely toxic substances. tion. On the other hand a hyperactive immune response can result in conditions such as hay fever atopic dermatitis or even chronic inflammation. BRM-4 demonstrates immune modulation characteristics because it up-regulates pro-inflammatory immune activity to destroy tumors but inhibits inflammatory activity in conditions of autoimmunity. BRM-4 can reduce the inflammatory response and help bring relief for a variety of inflammatory conditions including arthritis. BRM-4 has also shown anti-inflammatory properties in cases of irritable bowel syndrome hepatitis and atopic dermatitis. BRM-4 can reduce the symptoms of allergies by suppressing the degranulation of mast cells the storehouses of histamine which causes allergy symptoms. Human clinical and animal studies have shown that BRM-4 can be useful in the management of diabetes. In one clinical study diabetic subjects had decreased levels of glycohemoglobin (15 percent) with increased insulin levels (4 percent). In addition triglyceride and cholesterol levels were reduced. BRM-4 restores NK cell activity it helps the body get rid of aged or dead cells not just infected or malignant ones. This is a type of detoxification or drainage that takes place throughout our lives but slows down when NK cell activity declines with age resulting in congestion of the cellular environment. The use of BRM-4 is versatile not only in supporting the treatment of illness but also in preserving good health. References Riccardi C Giampietri A Migliorati G Cannarile L D Adamio L Herberman R Generation of mouse natural killer (NK) cell activity effect of interleukin2 (IL-2) and interferon (IFN) on the in vivo development of natural killer cells from bone marrow (BM) progenitor cells International Journal of Cancer 1986 Oct 15 38(4) 553-62. Kim H Kim J Yang S et al A polysaccharide extracted from rice bran fermented with Lentinus edodes enhances natural killer cell activity and exhibits anticancer effects. Journal of Medical Food 2007 Mar 10(1) 25-31. Bang M Van Piep T Thinh N et al Arabinoxylan Rice Bran (MGN-3) Enhances the Effects of Interventional Therapies for the Treatment of Hepatocellular Carcinoma A Three-year Randomized Clinical Trial Anticancer Research 2010 30 5145-5152. Cholujova D Jakubikova J Czako B et al MGN3 arabinoxylan rice bran modulates innate immunity in multiple myeloma patients Cancer Immunology Immunotherapy DOI 10.1007 s00262012-1344-z. Masood A Sheikh R Anwer R Biobran MGN-3 Effect of reducing side effects of chemotherapy in breast cancer patients Professional Medicine Journal Feb 2013 20(1) 013-016. Tai L de Souza C B langer S et al Preventing postoperative metastatic disease by inhibiting surgery-induced dysfunction in natural killer cells. Cancer Research 2013 Jan 1 73(1) 97-107. Qureshi A Sami S Khan F Effects of stabilized rice bran its soluble & fiber fractions on blood glucose levels & serum lipid parameters in humans with diabetes mellitus types I & II Journal of Nutritional Biochemistry 2002 13 175-187. Kamiya T Shikano M Tanaka M et al Therapeutic Effects of Biobran Modified Arabinoxylan Rice Bran in Improving Symptoms of Diarrhea Predominant or Mixed Type Irritable Bowel Syndrome A Pilot Randomized Controlled Study Evidence-Based Complementary and Alternative Medicine Hindawi Publishing Corporation Volume 2014 Article ID 828137. Ichihashi K Experience with Administration of BioBran in Patients with Chronic Rheumatism Clinical Pharmacology and Therapy 14 4 459463. Activating Leukocytes Especially NK Cells Can Have an Anti-aging Effect This aging process is called immune senescence. Because MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 27 2016 CAMInnovations DaVinci Laboratories of Vermont 20 New England Dr. Essex VT 05452 Email info davincilabs.com Website www.davincilabs.com Sleep Benefits leep disorders are one of the most common complaints encountered in medicine and psychiatry because of their negative effects on quality of life.1 One-third of all Americans experience a sleep disorder in their lives. Sleep deficits have also been implicated in obesity and weight gain 3 cardiovascular disease chronic fatigue as well as gastrointestinal and reproductive disorders.4 Lack of sleep increases all-cause mortality.2 Supporting healthy sleep patterns is therefore a fundamental component of a comprehensive health plan. Sleep Benefits has been formulated to work from three different angles to improve total sleep time and quality getting to sleep supporting sleep quality and staying asleep. S Sleep Benefits has been formulated to work from three different angles to improve total sleep time and quality getting to sleep supporting sleep quality and staying asleep. These changes demonstrate better quality sleep which produces greater mental physical and emotional rejuvenation. not intended to diagnose treat cure or prevent any disease. Getting To Sleep Bluenesse is a branded form and proprietary extract of lemon balm which has traditionally been used to not only support a healthy stress response but also to promote healthy sleep habits. This particular lemon balm extract is standardized to 6 percent rosmarinic acid and combines with an innovative bioassay-guided technology. Suntheanine L-Theanine enables the body to produce other calming amino acids such as dopamine GABA and tryptophan and helps support concentration focus deep muscle relaxation and improved quality sleep. GABA is an inhibitory neurotransmitter that helps to initiate and maintain sleep by suppressing arousal signals in the brain. Pharmacologic agents that enhance GABA levels are well known to induce sleep and are used to treat insomnia.5 Staying Asleep The final ingredient in this formula is Sensoril Ashwagandha and is intimately connected to the sleep cycle circadian rhythm and can have profound support assistance on the quality of sleep. The proposed mechanism by which this happens have been reported to influence GABA-ergic neurotransmission.8 In addition nourishing the adrenal glands can also provide metabolic and glucose support which balanced blood glucose levels is also very important to staying asleep. By addressing these three areas of sleep physiology the patient not only experiences short term sleep support but can also reap long term overall health rewards. These statements have not been evaluated by the Food and Drug Administration. This product is References 1 Lubit RH Ahmed I. Sleep disorders. Drugs & Diseases 2015 http emedicine.medscape.com article 287104-overview a5. Accessed Mar 30 2016. 2 Miller MA. The Role of Sleep and Sleep Disorders in the Development Diagnosis and Management of Neurocognitive Disorders. Front Neurol. 2015 6 224. 3 Chaput JP. Is sleep deprivation a contributor to obesity in children Eat Weight Disord. 2016 21(1) 54 Costa G. Sleep deprivation due to shift work. Handbook of clinical neurology. 2015 131 437-446. 5 Morgan PT Pace-Schott EF Mason GF et al. Cortical GABA levels in primary insomnia. Sleep. 2012 35(6) 807-814. 6 Hardeland R. Neurobiology pathophysiology and treatment of melatonin deficiency and dysfunction. The Scientific World Journal. 2012 2012 640389. 7 Jehan S Masters-Isarilov A Salifu I et al. Sleep Disorders in Postmenopausal Women. J Sleep Disord Ther. 2015 4(5). 8 Kumar A Kalonia H. Effect of Withania somnifera on Sleep-Wake Cycle in Sleep-Disturbed Rats Possible GABAergic Mechanism. Indian J Pharm Sci. 2008 70(6) 806-810. Supporting Quality Sleep Melatonin is among the most powerful sleep support nutrients and the dosage of 5 mg makes it all the more the potent. Melatonin is historically used to support a deep restful and refreshing sleep cycle. Melatonin is involved in the circadian rhythm. Darkness leads to a spike in melatonin which promotes the onset of sleep. Melatonin has a number of physiological activities including regulation of circadian rhythms antioxidant and supports immune capabilities. Melatonin and its analogs help to initiate promote and maintain sleep.6 7 28 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 2016 CAMInnovations EuroMedica 955 Challenger Dr. Green Bay WI 54311 Phone (866) 842-7256 Fax (920) 406-8172 Email info euromedicausa.com Website www.euromedicausa.com BCM-95 Curcumin With Turmeric Essential Oil Containing Turmerones T here is little debate that curcumin a compound extracted from the spice turmeric is a versatile and effective natural medicine. According to the American Botanical Council quoting 2014 SPINS data the turmeric curcumin category is the fastest growing supplement in the natural products industry with a 30 percent increase over the previous year. The National Institutes of Health (NIH) Institutes of Medicine s electronic database (PubMed.gov) lists more than 8 700 published studies with the search term curcumin ranging from major depression to cancer to hepatitis to autoimmune diseases and osteoarthritis--and this is a small sampling. When prescribing it is important to consider the differences between turmeric and curcumin and also the differing forms of curcumin formulations. Turmeric is a healthy spice but contains only 2 to 5 percent curcumin meaning that in 500 mg of turmeric there may be as little as 10 mg of curcumin. Therefore when attempting to replicate the amounts of curcumin used in clinical studies it is difficult to achieve optimal curcumin serum levels using turmeric. However one of the arguments in favor of turmeric is that this spice contains more healthy compounds than curcumin and this is correct--recent science has found that turmeric essential oils containing turmerones and ar-turmerones not only boost curcumin s activity in the body but have independent anti-inflammatory and anti-cancer properties. One solution is using a curcumin that is combined with turmeric essential oil which is the patented formulation used in BCM-95 Curcumin. This enhanced absorption curcumin has 27 published studies including three veterinary and 12 human clinical trials. In a trial of rheumatoid arthritis 500 mg curcuminoids in the form of BCM-95 Curcumin was given twice daily vs. 50 mg twice daily of the prescription nonsteroidal anti-inflammatory drug diclofenac sodium for eight weeks. Researchers found the BCM-95 worked as well as the drug and with a much lower rate of adverse effects. Curcumin is increasingly being investigated for its role in mental health as it becomes better understood that silent Curcumin is increasingly being investigated for its role in mental health as it becomes better understood that silent inflammation in the brain plays a significant role in the etiology of many psychiatric disorders. inflammation in the brain plays a significant role in the etiology of many psychiatric disorders. In a study of major depressive disorder BCM-95 Curcumin 500 mg BID was compared to the prescription drug fluoxetine (one brand name is Prozac) 20 mg qd for six weeks. It was found that BCM-95 Curcumin worked as well as the fluoxetine without adverse effects. Three human trials have been published on the antidepressant benefits of BCM-95 Curcumin. Another key finding was that the form of depression with poor response to selective serotonin reuptake inhibitors (SSRIs) antidepressant medication atypical depression had the highest response rate to BCM-95 Curcumin. In vitro studies of BCM-95 Curcumin many done at Baylor University Cancer Treatment Center in Dallas TX have found that curcumin can awaken dormant tumor suppressor genes that play a significant role in cancer prevention and recovery. It can also kill cancer stem cells which are cancer cells left behind after chemotherapy that become active at a later date and trigger new tumor formation and cancer recurrence. Researchers have found that the turmeric essential oil turmerones play an important role in BCM-95 Curcumin s efficacy as together they have greater activity than either alone. In addition to anti-cancer benefits BCM95 Curcumin has been used in a human prostate cancer study to explore its efficacy in preventing damage to the urinary tract during radiation therapy. Researchers found that adverse effects after treatment were significantly lower in the BCM-95 Curcumin group and it was also reported that this form of curcumin with turmeric essential oils did not interfere with the radiotherapy treatment in any way. Because BCM-95 is absorbed better than plain curcumin and because it is blended with turmeric essential oil containing turmerones these study results may not be reproducible using other forms of curcumin. For a full list of references visit www.naturalpractitionermag.com. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 29 2016 CAMInnovations Kyowa Hakko USA 600 Third Ave. 19th Fl. New York NY 10016 Phone (800) 596-9252 Websites www.kyowa-usa.com www.setriaglutathione.com Setria Glutathione G lutathione (GSH) is provided both through the diet and through endogenous synthesis. The best food sources are fresh fruits and vegetables and freshly prepared meats. Most methods of food processing destroy glutathione. Modern diets are often devoid of glutathione due to the excessive intake of processed foods. Dietary intakes of glutathione among Americans have been measured in at least two studies. In the first intakes ranged from a low of 3 milligrams per day to a high of about 150 mg per day with a mean intake of 35 mg per day. Another study found an even wider range of intakes among men--from 5 milligrams to 242 mg per day and 7 to 96 mg per day in women with most people regardless of gender falling below 60 mg per day. If the best diets provide close to 250 mg per day and the mean intake is only 35 mg there is a considerable gap in much of the population. Thus supplemental intake of 150-250 mg per day would be likely to ensure an adequate intake for most people. Because of endogenous synthesis glu- tathione has not been considered an essential nutrient and no recommended intake level has been established. Moreover the variable levels of glutathione in different tissues and organs present a challenge both to measuring status and estimating needs. Early studies did not find an appreciable increase in plasma levels after supplementation and thus it was thought that oral glutathione was not bioavailable. However over the past 20 years numerous studies have demonstrated that plasma levels are not indicative of levels in other tissues and that oral glutathione is bioavailable. Animal evidence suggests that it may be delivered preferentially to specific sites of high demand such as the lungs and intestines. GSH is present in all tissues and body fluids both inside and outside of cells. The entire body pool is made and degraded daily through a continuous turnover of both cellular and extracellular glutathione. bility that could be addressed through increased oral intake. The morning shortfall becomes even lower with advancing age. References Jones DP et al. Nutr Cancer. 1992 17 57-75. Jones DP. Natural Medicine Journal 3(2) February 2011. Aw TY Williams MW. Am J Physiol. 1992 263(5 Pt 1) G665-72. Kariya C et al. Am J Physiol Lung Cell Mol Physiol. 2007 292 L1590-97. Hagen TM et al. Am J Physiol. 1990 259 G524-29. Iantomasi T et al. Biochim Biophys Acta. 1997 1330 274-83. Aw et al. Chem Biol Interact. 1991 80 89-97. Hunjan MK Evered DF. Biochim Biophys Acta 1985 815 184-88. Vina et al. Br J Nutr. 1989 62 683-91. He M et al. J Nutr. 2004 134 1114-19. Favilli F et al. Br J Nutr. 1997 78(2) 293-300. Lang CA et al. J Lab Clin Med. 1992 120(5) 72025. Van Lieshout EM Peters WH. Carcinogenesis. 1998 Oct 19(10) 1873-5. Lang CA et al. J Lab Clin Med. 2002 140(6) 38081. Julius M et al J Clin Epidemiol. 1994 47(9) 102126. Ashfaq S et al. J Am Coll Cardiol. 2006 Mar 7 47(5) 1005-11. Richie JP et al. Nutr Cancer. 2008 60(4) 474-82. Flagg EW et al. Am J Epidemiol. 1994 139(5) 45365. Cohen SM et al. Br J Ophthalmol. 1994 Oct 78(10) 791-94. Coral K et al. Eye. 2006 Feb 20(2) 203-7. Richie P. et al. Randomized controlled trial of oral glutathione supplementation on body stores of glutathione. Eur J Nutr. March 2015. Volume 54 issue 2 pp 251-263. Moriarty SE et al. Free Radic Biol Med. 2003 35(12) 1582-88. Joshi PC et al. Am J Physiol Lung Cell Mol Physiol. 2007 292(4) L813-23. Blanco RA et al. Am J Clin Nutr. 2007 Oct 86(4) 1016-23. Centers for Disease Control and Prevention. www.cdc.gov nhcs data hus hus07.pdf Natural Medicines Comprehensive Database. www.naturaldatabase.com 12.18.2008. Witschi A et al. Eur J Clin Pharmacol. 1992 43(6) 667-69. Potential Benefits of Oral Supplementation A randomized double-blind placebo controlled study of 54 healthy adults revealed that glutathione levels of those taking 1 000 mg of Setria Glutathione a day for six months increased 30 to 35 percent in many compartments including red blood cells lymphocytes and plasma and of those taking 250 mg of Setria Glutathione increased in whole blood. And as glutathione stores increased in the high-dose group so did the function of natural killer (NK) cells a marker for increased immune defense. These findings are consistent with previous pre-clinical studies and indicate that long-term oral administration GSH is an effective means of enhancing body stores of GSH. Glutathione supplementation may help increase levels of glutathione in certain circumstances associated with low glutathione status including cigarette smoking heavy drinking use of large numbers of prescription and non-prescription medications and chemotherapy. Glutathione levels fluctuate diurnally with lowest levels found in the morning which may present a window of vulnera- 30 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 2016 CAMInnovations MitoQ Limited P.O. Box 1671 Shortland St. Auckland 1140 New Zealand Phone 64-9-309-0803 Fax 64-9-303-2986 Email customerservice mitoq.com Website www.mitoq.com MitoQ itochondria are organelles found in almost all human cells often described as the powerhouse of the cell as they are responsible for generating most of the cell s energy supply of adenosine triphosphate (ATP). Mitochondria are also involved in cell signalling growth and death.1 Given these vital roles it is not surprising that mitochondrial dysfunction is known or suspected to be a major causative or contributing factor in many degenerative diseases and in the aging process itself.2 The primary causative factor is thought to be damage to cellular structures and molecules by reactive oxygen species (ROS) formed during ATP production.2 ROS are usually scavenged by cellular antioxidants but our ability to counteract the damage diminishes with age and poor health. One of the most important cellular antioxidants is coenzyme Q10 (CoQ10). CoQ10 is a lipid-soluble vitamin-like molecule found primarily in mitochondria. CoQ10 neutralises ROS and transfers their electrons to other cellular processes. It therefore performs a crucial dual energy transfer and antioxidant role and is simultaneously recycled so it may perform this function repeatedly.3 CoQ10 levels can diminish as we age or if there is an increased demand due to disease.2 CoQ10 has poor oral bioavailability due to its low aqueous solubility and large M MitoQ Siliphos Milk Thistle Selenium Vitacholine 1 McBride HM et al. Mitochondria more than just a powerhouse. Curr Biol. 2006. 16 (14) R551 60. 2 Schapira AH. Mitochondrial disease. 2006. Lancet 368 (9529) 70 82. 3 Bentinger M et al. Coenzyme Q--biosynthesis and functions . Biochem Biophys Res Commun. 2010. 396 (1) 74 9. 4 Barakat A et al. Coenzyme Q10 oral bioavailability effect of formulation type. J Pharm Invest. 2013. 43 (6). 431-451. 5 Murphy MP Smith AJ. Targeting antioxidants to mitochondria by conjugation to lipophilic cations. Annu Rev Pharmacol Toxicol. 2007. 47. 629-56. 6 Chacko BK et al. Mitochondria-Targeted Ubiquinone (MitoQ) Decreases Ethanol-Dependent Micro and Macro Hepatosteatosis. 2011. Hepatology. 54. 153-163. 7 Gane EJ et al. The mitochondria-targeted antioxidant mitoquinone decreases liver damage in a phase II study of hepatitis C patients. 2010. Liver Int. 30 (7). 1019-26. 8 Mercer JR et al. The mitochondria-targeted antioxidant MitoQ decreases features of the metabolic syndrome in ATM ApoE mice. 2012. Free Radic Biol Med. 52. 841 49. 9 Chacko BK et al. Prevention of diabetic nephropathy in Protects the liver against ROS damage and inflammatory Ins2 -AkitaJ mice by the mitochonresponses caused by viruses alcohol drug damage NAFLD and dria-targeted therapy MitoQ. 2010. metabolic syndrome. Biochem. J. 2010. 432 9 19. 5-8 Supports healthy liver function and detoxification. 10 Serviddio G et al. A silybinphospholipid complex prevents mito Silybin the active ingredient in milk thistle displays chondrial dysfunction in a rodent model of nonalcoholic steatohepatianti-inflammatory antioxidant and antifibrotic properties and protects tis. 2010. J Pharmacol Exp Ther. liver mitochondria from oxidative stress.10 332(3) 922-32 Siliphos is a patented formula of silybin with absorption levels up to 10 11 Shilo S et al. Selenium suptimes that of standard silybin. plementation increases liver MnSOD expression Molecular mechanism for Selenium is an essential micronutrient shown to boost natural hepato-protection. 2008. J Inorg Biochem. 102 (1). 110-118. antioxidant enzyme levels in liver tissue.11 12 da Kosta KA et al. Choline deficiency increases lymphocyte Choline is an essential dietary nutrient for cell repair especially in apoptosis and DNA damage in the liver. A choline-deficient diet can induce liver dysfunction.12 humans. 2006. Am J Clin Nutr. 84(1). 88-94. molecular size which inhibits transport across biological membranes.4 Faced with this problem a proprietary new formulation of CoQ10 was developed named MitoQ in which the CoQ10 is attached to a lipid-soluble positively-charged ion.5 MitoQ passes easily through biological membranes and is actively transported across the negatively charged mitochondrial membranes themselves. This allows mitochondrial MitoQ concentrations to exceed 800 times that of standard CoQ10 supplements.5 Organs with high-energy demands such as the liver and kidneys have the most mitochondria.1 As such diseases of these organs have a very high correlation with mitochondrial dysfunction.2 Mitochondrial dysfunction has been observed in many liver diseases such as non-alcoholic fatty liver disease (NAFLD) hepatitis alcohol damage and metabolic syndrome.2 6-8 In the kidneys it is a major factor in the pathophysiology of diabetic nephropathy.2 9 MitoQ Liver is a proprietary combina- tion of ingredients scientifically proven to aid normal liver function. Taken daily in conjunction with a healthy diet and exercise MitoQ Liver can help protect against oxidative stress and safely support optimal liver health. References MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 31 2016 CAMInnovations Natural Partners Inc. 8445 E. Hartford Dr. Scottsdale AZ 85255 Phone (888) 633-7620 Fax (800) 862-1261 Email info naturalpartners.com Website www.naturalpartners.com www.npscript.com NP Script T his year Natural Partners celebrated 21 years as a leading distributor of highquality nutritional supplements to integrative practitioners and their patients. However there is more to Natural Partners than just supplying professional-grade products. The company s commitment to providing unparalleled customer service building partnerships with leading brands and being an educational resource for the wellness community has helped shape the way it does business. Natural Partners listens to practitioners and strives to find solutions to meet their needs and the increasing needs of their patients. The latest innovative service from Natural Partners is NP Script a free online patient dispensary and secure e-scripting tool that allows practitioners to extend their care beyond the bounds of their office. Under the connected care of a licensed health care practitioner patients can easily log in to their doctor s personalized storefront and order their recommended supplements or receive a personalized email with product recommendations and dosing instructions. A practitioner s NP Script site is available 24 hours a day seven days a week and can be accessed on any device. Patients are delivered their practitioner-recommended products right to their doorstep. The latest innovative service from Natural Partners is NP Script a free online patient dispensary and secure e-scripting tool that allows practitioners to extend their care beyond the bounds of their office. standardized practitioner-curated protocol recommendations or customized templates to send email blasts to their patient database making engagement with their patients even easier. NP Script is a proven tool helping thousands of practitioners provide the products their patients need in a quick secure and convenient way. NP Script is the ideal tool to help me in two important ways to keep my practice running smoothly and successfully--automation and patient compliance said Dr. Holly Lucille a practicing ND and acclaimed TV and radio host. The ease customization and patient engagement abilities save me time money and give me peace of mind. NP Script is a practice savior. With NP Script practitioners can expect the same exceptional concierge service that is quintessentially Natural Partners. The NP Script Concierge Team offers a range of services including demonstrations to highlight the benefits of the site. They can guide practitioners through the set-up process or have a member of the NP Script team create the site for them. Patients will appreciate the same high-level of service with the option to place phone orders directly with a friendly and knowledgeable member of the NP Script team. The development and launch of NP Script is one recent demonstration of Natural Partners commitment to the wellness community. Earlier this year Natural Partners launched its inaugural Advisory Board and expanded its corporate headquarters to include the new Natural Partners Media Training Center. These new capabilities are intended to both help facilitate successful patient outcomes and do their part in demonstrating the value of engaging with a health care practitioner. Whether you have a practice that maintains a physical on-site supplement inventory or are new to nutritional supplement recommendations and prefer a virtual online patient dispensary via NP Script Natural Partners is there for all health care practitioners. For more information about getting started with your online patient dispensary with NP Script please visit npscript.com. To learn more about Natural Partners visit www.naturalpartners.com. NP Script has revolutionized patient compliance for integrative medicine practitioners. Through their online dispensary practitioners can ensure patients are supplied with professional-grade supplements that align exactly with their treatment protocols and can monitor compliance to those treatment plans. Health care practitioners can also utilize NP Script to communicate directly to patients via customized communication tools. Through this service they can use e-scripting to send 32 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 2016 CAMInnovations Seroyal 112 Technology Dr. Pittsburgh PA 15275 Phone (888) 737-6925 Fax (877) 737-6925 Email sales seroyal.com Website www.seroyal.com Research-driven GENESTRA BRANDS HMF Probiotics ENESTRA BRANDS has been instrumental in driving probiotic science and innovation for more than 30 years. In collaboration with Dr. Nigel Plummer a renowned probiotic contributor with more than 100 published research studies GENESTRA BRANDS has developed and manufactured a probiotic consortium known as Human MicroFlora (HMF). Dr. Plummer and his team of scientists at Cultech Ltd. have more than 20 years of experience in probiotic discovery and development and have spent the last 15 years conducting clinical research to prove the effectiveness of this probiotic consortium. In vitro research demonstrates that HMF probiotics are naturally resistant to pH and bile thus maximizing intestinal tract exposure and eliminating the need for enteric coatings.1-5 HMF strains also have a naturally strong adherence to epithelial cells ensuring high ratios of intestinal tract carriage.1-5 These strains have been clinically studied in seven placebo-controlled trials which have demonstrated their ability to support healthy microflora balance gastrointestinal comfort immune function and skin health.6-12 A shift in the balance of bacteria from those normally present in the intestines to G those that produce high levels of gas may be responsible for gastrointestinal discomfort.13 As HMF strains have been demonstrated to support a healthy bacterial balance a doubleblind placebo-controlled trial was conducted to determine the potential of HMF probiotics to reduce occasional intestinal discomfort.7-10 Fifty-two adults experiencing occasional intestinal discomfort were randomized to consume one placebo or probiotic capsule (HMF Intensive) daily for eight weeks.10 Participants scored their intestinal discomfort (including bloating satisfaction with bowel habits and quality of life) at baseline and biweekly for 10 weeks.10 Probiotic supplementation decreased the number of days with intestinal discomfort while improving satisfaction with bowel habits and bloating symptom scores (Figures 1-2).10 The probiotic consortium used in this study is also available in a convenient powder form (HMF Intensive Powder) to help promote intestinal comfort in adults. Supplementation with HMF probiotics and prebiotic fiber was shown to promote immune health in an ex-vivo study involving adult volunteers.14 Similarly vitamin C was shown to modulate cytokine activity in adultderived immune cells.15 However no studies had investigated the effects of combined probiotic and vitamin C intake on immune health in children.11 Therefore the Cultech Ltd. researchers conducted a randomized double-blind placebo-controlled study to evaluate the effects of HMF probiotics and vitamin C on immune health in young children attending preschool.11 Fifty-seven children aged 3 to 6 were randomized to consume one chewable placebo or probiotic vitamin C tablet (the same probiotic consortium and vitamin C level present in HMF Fit for School) daily for six months.11 Upper respiratory tract health was monitored through weekly diaries completed by guardians and during at least three physician s appointments.11 When compared to the placebo the HMF vitamin C combination significantly promoted upper respiratory tract health and immune function.11 This research was used to develop HMF Fit for School which also includes vitamin D for additional immune support.16 Probiotics may support skin health by mediating IgE-associated immune responses which are linked to skin sensitivity.17 Cultech Ltd. provided the probiotic supplement for a randomized double-blind placebo-controlled trial evaluating the effects of probiotics administered to 454 mother infant pairs.12 Pregnant women at 36 weeks gestation were assigned to either the placebo or probiotic (HMF Maternity) group consuming one capsule daily until delivery.12 After birth their infants consumed the same capsule type once daily for six months.12 Skin sensitivity was evaluated at six months and two years of age through skin-prick tests. In comparison with infants in the placebo group those in the probiotic group experienced a statistically significant 57 percent decrease in skin sensitivity (Figure 3).12 As research has also demonstrated that combined supplementation with HMF probiotics and prebiotic fiber supports healthy immune responses HMF Baby B (breast-fed babies) and Baby F (formula-fed babies) were developed using the same probiotic consortium administered in this study HMF Baby B contains galactooligosaccharides while HMF Baby F contains both galactooligosaccharides and fructooligosaccharides.14 GENESTRA BRANDS dedication to research extends beyond its own needs benefitting the dietary supplement industry as a whole. The knowledge gained during these research studies fuels product innovation to help produce novel products that can be tailored to suit the needs of different populations. Alongside Cultech Ltd. GENESTRA BRANDS will continue its groundbreaking research initiatives to provide health care practitioners with the highest quality and most reliable products ensuring that we repeatedly exceed their expectations. This will allow the company to achieve its shared mission of making a difference in people s lives. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. For a full list of references visit www.naturalpractitionermag.com. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 33 PRODUCT FOCUS When Natural Detox is Not Enough T he liver is the second largest organ in the human body. It helps digest food store energy and remove toxins but our environment has changed and toxins may overwhelm the liver. According to the Liver Foundation there are more than 100 liver diseases and one out of every 10 Americans is affected by liver disease. In addition liver disease is one of the top 10 causes for death in the U.S. The liver isn t the only organ that is working hard to keep the body operating optimally. The kidneys also extract waste from blood balance body fluids form urine and aid in multiple other crucial functions in the body. According to the National Institute of Diabetes and Digestive and Kidney Disease kidneys filter about 120-150 quarts of blood to produce about 1 to 2 quarts of urine composed of wastes and extra fluid. Kidneys make hormones that regulate blood pressure make red blood cells and By Corinne Anderson help bones stay strong as well as keeping electrolytes stable. The kidneys play a crucial role in maintaining overall health but are rarely appreciated until they become damaged and can no longer do their jobs the National Kidney Foundation said. Of course there are always avenues for prevention. Encouraging patients to have a healthy lifestyle is first and foremost. Eating foods from all the food groups and maintaining a healthy weight is ideal. Limiting the intake of alcohol and managing medications appropriately are also important as well as avoiding toxins in the environment like cleaning chemicals cigarettes insecticides etc. the Liver Foundation stated. However even with healthy weight limited alcohol and a conscious avoidance of toxins the body still comes into contact with unhealthy things--it is practically unavoidable. In addition like liver disease kidney disease in children and teens is most often due to congenital birth defects or genetic diseases. And as people get older other acquired diseases are more common such as high blood pressure diabetes and inflammatory diseases such as glomerulonephritis (inflammation of the kidney). Certain diseases run in families and affect all age groups. Anyone at any age including children can be affected by kidney disease. A composition of lifestyle location genetics and environment play a huge part in overall health. It is important to supplement these essential organs in order to keep the body healthy and operating optimally. Below are a few products that can aid patients in healthy maintenance of liver and kidney function. Livit-1 & Livit-2 Livit-1 by Ayush Herbs Inc. is used in ayurvedic medicine for liver disorders particularly hepatitis B C and jaundice as it is known for its hepatoprotective and liver detoxifying properties. Other conditions for use include indigestion dyspepsia respiratory diabetes asthma gonorrhea influenza colic menorrhagia and disorders of the urogenital system and kidneys. Livit-1 properties also include astringent cardioprotective stomachic diuretic febrifugal antiseptic anti-viral chemoprotective anti-cancer antiinflammatory anti-fertility and antioxidant properties the company stated. Per Ayush Herbs dosage is one pill one to three times daily (suggested price 28 90-ct. tablets). Livit-2 is an ancient formula combining 16 ingredients that synergistically protect support restore and detoxify the liver. Other properties include bitter tonic antiinflammatory cholagogue laxative and immunomodulator. Livit-2 comes in a 90tablet container for a suggested price of 33 and a recommended dosage of one pill one to three times daily. For more information call (425) 637-1400 or visit www.ayush.com. Lipoic & Thisibilin Lipoic (alpha-lipoic acid) by Bio-Tech Pharmacal Inc. is a naturally occurring compound that serves as a cofactor for enzymes involved in metabolism and energy production. Lipoic (suggested price 29 100 capsules) is a potent and fat-soluble antioxidant that can regenerate the activity of other antioxidants. Research suggests that lipoic acid also promotes healthy glucose metabolism good circulation and detoxification. Supplementation with lipoic acid may support cardiovascular nerve and eye health in addition to being halal certified. In addition Bio-Tech also offers Thisibilin a milk thistle extract derived from the seeds of the Silybum marianum plant. This antioxidant-rich extract is known through tradition and research to support liver and kidney health. Supplementation with milk thistle also promotes the production of bile a digestive fluid that aids in nutrient absorption and chemical detoxification and supports natural inflammatory responses in the maintenance of blood sugar levels already within the normal range. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. For more information call (800) 345-1199 or visit www.biotechpharmacal.com. 34 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Go to www.naturalpractitionermag.com mitoq for info about this advertiser PRODUCT FOCUS Liverubin Liverubin by AlchemLife is one of the first highly water-soluble silymarin tablets with enhanced bioavailability. Silymarin the main ingredient found in Liverubin is derived from milk thistle. It has been used for centuries in ayurvedic practices to promote healthy liver function. Liverbuin safely provides the highest level of purity and potency and overall support helping patients maintain normal healthy liver function the company said. Each 30-ct. box of Liverubin has a suggested price of 19.99. For more information call (281) 208-7518 or visit www.liverubin.com. Soy Lecithin & Liver Detox LIFE Nutrition offers Soy Lecithin which acts as a structural barrier for cell membranes and regulates transportation of nutrients in cells. Made with high concentrated non-GMO (genetically modified organism) soy lecithin it contains all the benefits you need for a healthy liver heart and nervous system. It also helps promote liver fat metabolism and improve blood circulation. Each 90-ct. soft gel bottle has a suggested price of 18. In addition Liver Detox (suggested price 35 for 60 soft gels) contains five potent herbal extracts to give the liver a daily three-step (Block Flush & Regenerate) natural detox. Milk thistle helps block the toxin from entering liver cells and avoid free radical damage from harmful substances entering liver. Dandelion and turmeric help increase bile production and flush out toxins in the liver. Artichoke and schisandra help regenerate and replenish liver cells to maintain optimal liver health. Liver Detox and Soy Lecithin are free of GMOs gluten artificial colors and flavors. For more information call (888) 865-9422 or visit www.lifenutrition.com. Liver Support & Detoxification New from Genestra Brands Liver Support & Detoxification vegetable capsules provide a combination of nutrients and herbs that promote antioxidant support and a healthy liver the primary organ responsible for cleaning and detoxifying the blood. Liver Support & Detoxification provides standardized extracts from milk thistle seed turmeric rhizome and licorice root. Research demonstrates that milk thistle increases the activity of detoxifying enzymes in the liver. Along with active ingredients in turmeric and licorice milk thistle supports and enhances the body s antioxidant defense system. Liver Support & Detoxification is gluten- and dairy free and is ideal for vegans each 60-capsule bottle has a suggested retail price 28.70 to the patient and a practitioner price of 15.10. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. Hepatiben Hepatiben by Liver Medic is a powerful formulation that addresses the primary pathology of today s liver problems by dedicating half of its ingredients to leaky gut support (phosphatidylcholine berberine glutathione alpha lipoic acid) and the other half to liver detoxification (silybin MSM SAMe NAC). Just the silybin combined with phosphatidylcholine s enhancing effects alone is equivalent to 4 000-6 000 mg of milk thistle. A four capsule dose supports normal liver enzyme and blood sugar levels. A lower dose of two capsules is used for daily liver maintenance. Each 60-ct. bottle has a suggested price of 37.99. For more information call (800) 387-2278 or visit www.livermedic.com. For more information call (888) 737-6925 or visit www.seroyal.com brands genestrabrands. Hevert Detox Liver & Kidney Hevert Pharmaceutical s Detox Kit is a gentle solution to support and stimulate the detoxification processes of the body. Today s patients are exposed to a variety of factors ranging from stress to environmental factors that disrupt the body s self-regulatory mechanisms-- Hevert s homeopathic detox products are a tool for restoring balance and supporting health and wellness. They offer support for drainage and detoxification and help to stimulate regulation in the body. Hevert Detox Liver stimulates and boosts the lymph flow promotes regeneration of damaged liver cells and improves drainage of toxins via the hepatobiliary system. The active ingredients include Carduus marianus TM Chelidonium 3X and Taraxacum 3X. Hevert Detox Kidney stimulates evacuation via the kidneys increases perfusion of the kidneys and is anti-inflammatory. Active ingredients include acidum nitricum 6X apis 3X belladonna 6X cantharis 4X juniperus communis 3X and solidago virgaurea TM. Each 1.7-fl.-oz. bottle has a suggested retail price of 24.95 and a practitioner price of 14.25. For more information call (720) 598-3037 or visit www.hevertusa.com. MitoQ Liver MitoQ Liver is a targeted antioxidant that supports liver function and detoxification. MitoQ Liver (suggested price 69.95 60capsules) is a ground-breaking formula featuring patented MitoQ which is 847 times more effective than CoQ10 at targeting liver mitochondria. It helps repair oxidative damage to hepatocytes and supports healthy liver function and detoxification when taken daily. It also contains Siliphos milk thistle selenium and choline essential liver support ingredients. Each vegetable capsule contains mitoquinol mesylate (mitoquinol 5 mg) choline bitartrate 135 mg (choline 55 mg) Siliphos milk thistle 80 mg (sylibin 24.6 mg) selenocysteine 53 mcg (selenium 25 mcg). The adult dosage is two capsules day the company stated. For more information visit www.mitoq.com. 36 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Detox Drainage Liver & Kidney OHM Pharma Inc. released improved homeopathic Detox Drainage Kidney and Detox Drainage Liver formulas. Both are a synergetic combination of HPUS approved homeopathic remedies that temporarily relieve slow dysfunctional renal metabolism stimulating kidney function to remove toxins and improving drainage sagely and naturally with no side effects. Both products are prepared with non-GMO kosher-certified cane alcohol and vegetable glycerin. Products are free of corn gluten and allergens safe for both children and adults. The Detox Drainage Kidney and Detox Drainage Liver come in 2-oz. spray bottles for a suggested retail price 24.50 and is sold exclusively to health care practitioners. For more information call (940) 325-4797 or visit www.ohmpharma.com. Liver Resilience Liver Resilience by Progressive Laboratories utilizes a unique combination of clinically studied botanicals to provide nutrients necessary to support healthy liver function Siliphos milk thistle extract Extramel superoxide dismutase (SOD) Sesamin sesame seed extract Schisandra chinesis fruit extract ginger and vitamin E. These ingredients in Liver Resilience work synergistically to support liver health by reduction of oxidative stress enhancement of insulin sensitivity regeneration of hepatocytes inhibition of fat accumulation beneficial epigenetic effects increased metabolism and excretion of hepatotoxins enhancement of ATP production and many other supportive pathways. Each 30-ct. bottle (one month supply) has a suggested price of 36. For more information call (800) 527-9512 or visit www.progessivelabs.com. PRACTITIONER CORNER (Continued from page 8) largely attributable to the phenolic compound chebulic acid.16 Haritaki s antioxidant activities have also been shown to decrease lipid oxidation.17 The research on amla and haritaki supports the results of studies looking at the entire triphala combination. Triphala shows great promise in the treatment of cardiovascular disease. Science is providing exciting validation for the ancient wisdom that created triphala and extolled to as a primary intervention in health care. indica-effectiveness for dyslipidemia. Anila L1 Vijayalakshmi NR. 7 Indian J Clin Biochem. 2008 Oct 23(4) 378-81. doi 10.1007 s12291-008-0083-6. Epub 2008 Dec 20. A Pilot clinical study to evaluate the effect of Emblica officinalis extract (Amlamax) on markers of systemic inflammation and dyslipidemia. Antony B Benny M Kaimal TN. 8 Diabetes Metab Syndr Obes. 2013 Jul 26 6 27584. doi 10.2147 DMSO.S46341. Print 2013. Effects of Phyllanthus emblica extract on endothelial dysfunction and biomarkers of oxidative stress in patients with type 2 diabetes mellitus a randomized double-blind controlled study. Usharani P Fatima N Muralidhar N. 9 J Med Food. 2015 Mar 10. [Epub ahead of print] Supplementation of a Standardized Extract from Phyllanthus emblica Improves Cardiovascular Risk Factors and Platelet Aggregation in Overweight Class-1 Obese Adults. Khanna S Das A Spieldenner J Rink C Roy S. 10 J Med Assoc Thai. 2013 Jan 96 Suppl 1 S40-8. Protective effect of Phyllanthus emblica fruit extract against hydrogen peroxide-induced endothelial cell death. Wongpradabchai S Chularojmontri L Phornchirasilp S Wattanapitayakul SK. 11 Evid Based Complement Alternat Med. 2013 2013 720728. doi 10.1155 2013 720728. Epub 2013 Mar 31. Phyllanthus emblica L. Enhances Human Umbilical Vein Endothelial Wound Healing and Sprouting. Chularojmontri L Suwatronnakorn M Wattanapitayakul SK. 12 Yakugaku Zasshi. 2005 Jul 125(7) 587-91. Antiatherogenic effects of phyllanthus emblica associated with corilagin and its analogue. Duan W Yu Y Zhang L. 13 Pharm Biol. 2015 Jan 27 1-8. [Epub ahead of print] Anti-hyperlipidemic effect of methanol bark extract of Terminalia chebula in male albino Wistar rats. Reddy MM Dhas Devavaram J Dhas J Adeghate E Starling Emerald B. 14 J Adv Pharm Technol Res. 2010 Apr 1(2) 22935. Hypolipidemic activity of haritaki (terminalia chebula) in atherogenic diet induced hyperlipidemic rats. Maruthappan V Shree KS. 15 Planta Med. 2011 Jul 77(10) 1060-7. doi 10.1055 s-0030-1270748. Epub 2011 Feb 9. Inhibitory effects of Terminalia chebula extract on glycation and endothelial cell adhesion. Lee HS Cho HY Park KW Kim IH Kim JT Nam MH Lee KW. 16 J Ethnopharmacol. 2010 Oct 5 131(3) 567-74. doi 10.1016 j.jep.2010.07.039. Epub 2010 Jul 24. Preventive effects of chebulic acid isolated from Terminalia chebula on advanced glycation endproduct-induced endothelial cell dysfunction. Lee HS Koo YC Suh HJ Kim KY Lee KW. 17 Indian J Biochem Biophys. 2005 Aug 42(4) 246-9. Antioxidant activity of ethanolic extract of Terminalia chebula fruit against isoproterenol-induced oxidative stress in rats. Suchalatha S Srinivasulu C Devi S. References 1 Daru. 2012 Sep 10 20(1) 33. doi 10.1186 20082231-20-33. Efficacy of Itrifal Saghir a combination of three medicinal plants in the treatment of obesity A randomized controlled trial. Kamali SH1 Khalaj AR Hasani-Ranjbar S Esfehani MM Kamalinejad M Soheil O Kamali SA. 2 Yakugaku Zasshi. 2007 Feb 127(2) 385-8. Hypolipidemic effect of triphala in experimentally induced hypercholesteremic rats. Saravanan S Srikumar R Manikandan S Jeya Parthasarathy N Sheela Devi R. 3 Altern Ther Health Med. 2012 Nov-Dec 18(6) 3845. Triphala and its constituents ameliorate visceral adiposity from a high-fat diet in mice with dietinduced obesity. Gurjar S Pal A Kapur S. 4 Phytother Res. 2005 Jul 19(7) 582-6. In vitro antioxidant studies and free radical reactions of triphala an ayurvedic formulation and its constituents. Naik GH Priyadarsini KI Bhagirathi RG Mishra B Mishra KP Banavalikar MM Mohan H. 5 Climacteric. 2015 Apr 18(2) 299-310. doi 10.3109 13697137.2014.933408. Epub 2014 Sep 6. Amla prevents fructose-induced hepatic steatosis in ovariectomized rats role of liver FXR and LXR. Koshy SM1 Bobby Z Jacob SE Ananthanarayanan PH Sridhar MG Paulose DT. 6 J Ethnopharmacology 2002 Jan 79(1) 81-7. Flavonoids from Emblica officinalis and Mangifera Shailinder Sodhi ND Growing up near the Himalayas Dr. Shailinder Sodhi developed an early interest in ayurvedic plants and herbs and received his BAMS (bachelor in ayurvedic medicine and surgery) degree from Dayanand Ayurvedic College in Jalandhar India in 1985. In 1993 he received a naturopathic medicine degree from Bastyr University as well as a degree in diagnostic ultrasound from Bellevue College. Dr. Sodhi practices naturopathic medicine along with his wife Dr. Anju Sodhi and his brother Dr. Virender Sodhi at the Ayurvedic and Naturopathic Medical Clinic in Bellevue WA which he established in 1989. In addition Dr. Sodhi serves as president of Ayush Herbs Inc. a manufacturer of high-quality ayurvedic herbal formulas is an adjunct faculty member at Bastyr and has been published in several natural health magazines. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 37 PRACTITIONER CHAT WITH SHARI BARBANEL L Leo Galland MD www.drgalland.com Facebook facebook.com leogallandmd Twitter LeoGallandMD eo Galland MD a board-certified internist is recognized as a world leader in integrated medicine. Educated at Harvard University and NYU (New York University) School of Medicine he won the Linus Pauling Award for his trailblazing vision that created a new way to practice medicine for thousands of doctors. Dr. Galland has been featured in The New York Times The Wall Street Journal Self and Men s Fitness and has appeared on the TODAY Show Good Morning America the Dr. Oz Show PBS CNN and Fox. He is the author of The Fat Resistance Diet Power Healing and Superimmunity for Kids and the director of the Foundation for Integrated Medicine. Jonathan Galland JD a leader in integrated health education is a health writer for the Huffington Post and MindBodyGreen. He holds a degree in law which supports his research and presentation of the environmental health aspects for The Allergy Solution expanding the book to include a strong environmental message. To help educate the public on the impact of allergies in their lives Galland co-wrote the script for the upcoming public TV special on The Allergy Solution. Jonathan Galland JD Facebook facebook.com jonathangallandjd Twitter JonathanGalland epidemic inspired us to write our new book The Allergy Solution Unlock the Surprising Hidden Truth about Why You Are Sick and How to Get Well. We reveal the proven role of allergy in causing weight gain fatigue headache joint and muscle pain a range of digestive symptoms from heartburn to diarrhea mood problems poor mental focus and more. A step-by-step method for determining if you have hidden allergies is provided. And if you suffer from classic allergies like rhinitis eczema or have asthma our program addresses these issues from a nutritional and lifestyle perspective. It s a hidden epidemic that s sweeping the world. You may not think of yourself as allergic. Your nose may not run and your skin doesn t itch. But you have common complaints that just won t go away. Do you suffer from Weight gain Stomachaches Insomnia Headaches Fatigue Depression or anxiety Brain fog A hidden allergy is often the culprit. Chronic conditions that were previously diagnosed as autoimmune diseases psychiatric disorders or many others wind up being allergic in origin. Our search for answers to common mystery conditions and the source of the allergy Q A What is the allergy epidemic Allergic disorders have increased dramatically over the past few decades. Allergies were once rare. Today they affect over a billion people. Environmental toxicity depletion of beneficial intestinal bacteria and fast food all contribute to allergies. Environmental toxins damage your body s surfaces like the respiratory or intestinal lining or the skin. The damaged lining tissue becomes a site where allergy develops. Good nutrition can stop the cycle from snowballing. Allergic diseases were once rare--quirky reactions that only a few people would get. Today allergic disorders are among the most common medical conditions in the world. Do you have any idea how many people have allergies More than one billion. While just 50 years ago one person in 30 had allergies today that number is one in three and rising. Q A Why are we seeing an epidemic of allergy disorders today Poor nutrition and environmental toxins create vicious cycles that drive the allergy epidemic. Toxins damage a surface of the body--the respiratory lining or the skin or the intestinal lining. The damaged lining tissue becomes a site where allergy develops. Research shows that nutrition can help stop the cycle from snowballing. Examples include automotive and industrial emissions that damage the lining of our respiratory tracts and increase the inflammation we experience when exposed to pollen. These pollutants also make allergenic plants produce more pollen and it s a pollen that is more allergenic than normal pollen. A new chemical comes out of a laboratory somewhere in the world every 2.6 seconds. That s about a million a year. Over 100 000 of these have made their way into our homes hidden in cleaning solutions personal care products clothing and furnishings. Spray cleaners air fresheners fragrances and formaldehyde are proven to increase the risk of developing allergies and asthma. The Allergy Solution contains a program for freeing your home from these toxins. We call it Mission Detoxable. Q A What is causing this epidemic to occur The first hidden truth is simple but surprising Fast food causes allergies. In fact it only takes three fast food meals a week for this effect to be seen. The International Study of Asthma and Allergies in Children-- the ISAAC study found that the more you Q A Can you explain the Four Gamechanging Truths about allergies 38 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 eat fast food the greater the likelihood you ll develop allergies. What is it in fast food that makes you allergic It s the unhealthy fats and sugar and also it s what you don t get when you eat fast food the nutrients your body needs to balance immune function. The second hidden truth is this Allergies like disguises. They often masquerade as conditions you never thought of as allergic such as headaches weight you can t lose and much more. Our world is full of unseen allergic triggers too. That discovery leads to my third hidden truth The triggers for allergy often hide in plain sight such as mold toxins in the home or dust mites. We ve found a common thread that runs through many of my patients cases it leads to a place where the key to health is hidden within each of us our digestive system the gut. That discovery led to the fourth hidden truth allergies start in our gut. The bacteria living in our digestive tract have a huge impact on our immunity because two-thirds of our immune system is located in the intestines. These immune cells are controlled by the microbes in our gut. There s one thing all the research makes clear our immune system needs a diversity of good bacteria. In that way it s just like a rainforest. Biodiversity is a sign of health and we now know that loss of diversity of gut microbes causes allergy. Clinical research has shown a strong link between allergies and weight gain. If your patients have allergies they are more likely to become overweight than if they don t. If they re already overweight they re more likely to develop allergies. Laboratory studies from many centers including Harvard Medical School show that allergic reactions can actually make fat cells grow larger--as fat cells expand they unleash stronger allergic reactions. A Research shows that people with allergies often suffer from nutritional deficiencies and may need nutritional enrichment of protective factors like selenium magnesium vitamins C and D and omega-3 fats. In The Allergy Solution we provide a nutritional approach to overcoming allergy through food and supplements. Q A Q A Q How does nutrition impact allergies Two-thirds of your immune system is located in your intestinal tract. The gut is like a boot camp for training your immune cells. The drill sergeants are the bacteria living in your intestines. Biodiversity of these bacteria is essential for immune health and protects against allergy. Antibiotics pesticides herbicides disinfectants and the modern diet all destroy this diversity and contribute to the allergy epidemic. Our book contains a program for overcoming allergies by healing your gut. It s called ARC for Avoidance Reflorastation and Cultivation. What steps can practitioners take to help their patients relieve their symptoms Make sure to address and account for the three levels of environment and their impacts on your patients allergies and overall health the outdoor environment the indoor environment (in their home and at work) and the internal environment their gut and skin where part of their hundred trillion bacteria could be out of balance. If you follow the steps outlined in The Allergy Solution not only will you be better equipped to uncover the hidden allergies that are likely impacting your patients health but better armed to decrease their toxic exposures eliminate many of the toxins they have accumulated improve their diet and lifestyle regimens and put them on a path to optimum health. A Q A How important is glutathione to the body Why Glutathione helps to protect your T regulatory cells (or T-reg) from damage a lack of it makes T-regs susceptible to destruction brought on by environmental and food toxins which is one factor contributing to the epidemic of allergy. What s the role of the gut in creating or defending against allergy We think of it as hitting the reset button on your computer. For three days you eat only a nourishing soup a tasty smoothie and a soothing tea. The foods in the Power Wash include vegetables fruits and seeds that supercharge your cells with nutrients that satisfy your hunger. They ve been chosen because they support the function of a critical part of your immune system regulatory T-lymphocytes. We call them T-regs. Their role is to turn off the unwanted immune reactions that create allergies. If you have allergies you suffer from defective function of T-regs. Our program is designed to provide nutritional support for T-regs which comes from natural folates found in leafy greens carotenoids found in orange and yellow vegetables and the bioflavonoids found in parsley strawberries and oolong tea. We also present research on the protective capacity of broccoli and other cruciferous vegetables. Q A What is the Three-day Power Wash Q What is the connection between allergies and weight gain MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 39 SUPPLEMENTSCIENCE Vitamin K2 By Gene Bruno MS MHS Huntington College of Health Sciences ach year more research is being conducted on vitamin K2. In fact in just the past year I ve personally had two scientific reviews on vitamin K2 published in peer-reviewed journals. The first one examined vitamin K2 s cardiovascular roles and the second reveals the prevalence of vitamin K2 deficiency insufficiency. Here I ll provide an overview of the research I presented in two peer-reviewed articles. But before jumping right into this recently published research let s take a quick look at some background information regarding vitamin K. Research on New E and intestinal microbiota synthesizes a range of K2 forms collectively referred to as menaquinones.3 The menaquinones have a number designation according to the number of repeating 5-carbon units in its side chain. For example if there are seven repeating 5-carbon units the designation will be menaquinone-7 or MK-7.4 Among the menaquinones the MK-7 form of vitamin K2 has had the most significant research behind it supporting is value in human health. osteoblasts) and matrix Gla protein (MGP found in cartilage bone and soft tissue including blood vessel walls). These proteins are local inhibitors of calcification in the tissues in which they exert their function. Carboxylation and Vitamin K2 arboxylation is a process in which a carboxylic acid group is reacted with a substance such as a protein--and carboxylation is necessary for the formation of critical VKDPs that have a positive impact on bone strength and arterial stiffness. Since 10 to 40 percent of VKDPs remain undercarboxylated research was conducted showing that the MK7 form of vitamin K2 was more effective than vitamin K2 and increasing the carboxylation of VKDPs. This was true when doses of 90 mcg or more of MK-7 were used daily. The Cardiovascular Benefits of Vitamin K2 In the July August 2015 issue of the journal Agro Food Industry Hi Tech 5 my co-author and I discussed research showing that the primary way in which vitamin K acts to promote cardiovascular health is by inhibiting calcification in the arteries--which would otherwise lead to atherosclerosis. Specifically some of the 17 VKDPs have been identified to date act as calcification inhibitors. These include osteocalcin (OC) also known as bone Gla protein (synthesized by C Background Discovered in 1929 vitamin K was originally identified for its role as a blood-clotting (coagulation) cofactor.1 In the 1970s vitamin K-dependent proteins (VKDPs) were discovered which led to a more comprehensive understanding of vitamin K s role with respect to bone and cardiovascular health.2 Additionally two forms of this fat soluble vitamin exist vitamin K1 and K2. Plants synthesize phylloquinone (aka vitamin K1) 40 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 We also discussed the population-based Rotterdam study 6 which included 4 807 subjects and which provided the first evidence for a link between vitamin K and vascular health. The results showed the relative risk of coronary heart disease mortality and calcification of the aorta (an artery in the heart) was reduced in those with high intakes of vitamin K2 compared to those with a lower intake. The intake of vitamin K1 however was not associated with these same cardiovascular benefits. Another study 7 with 564 post-menopausal also showed a decreased risk of coronary calcification with higher intakes of vitamin K2 but not vitamin K1. In a three-year double-blind placebocontrolled trial 248 postmenopausal women received 180 mcg day of MK-7 (MenaQ7) or a placebo for three years to examine the effect on arterial stiffness (i.e. caused by calcification). The results were that supplementation with MK-7 significantly decreased measures of aortic stiffness and improved undercarboxylated VKDPs by 50 percent. Vitamin K2 Deficiency Insufficiency In the January 2016 issue of the Journal of Human Nutrition & Food Science 8 I discussed research suggesting that recommendations for vitamin K2 be increased to 180 mcg day for adults up from its current adequate intake levels of 90-120 g day for women and men respectively. The basis for this includes that facts that vitamin K Has poor bioavailability from food Has low circulation in the blood Is quickly metabolized and excreted Has low tissue stores Levels are often measured by an inadequate method The Food and Agriculture Organization of the United Nations estimates that the absorption of vitamin K from boiled spinach (a good source of vitamin K) is no greater than 10 percent. Furthermore relatively small amounts of vitamin K circulate in the blood compared to the other fat-soluble vitamins with about 70 percent being excreted in the feces and urine from an oral dose of vitamin K1. Due to its rapid metabolism circulating vitamin K levels is not dependable as measures of vitamin K status. Currently prothrombin time (a measure of how long it takes blood to clot) is typically used to assess vitamin K status but this is not routinely done except in individuals who take anticoagulants or have bleeding disorders. The problem is that changes in vitamin K intakes have rarely been shown to alter prothrombin time. Hence prothrombin time is not really an effective way to meas- ure vitamin K status. Rather a much better method is to measure circulating levels of specific undercarboxylated VKDPs such as undercarboxylated MGP and undercarboxylated OC. Higher levels of either of these reflect lower levels of vitamin K. In a study of 452 men and women (age range 60 80 years) undercarboxylated MGP was measured. Results showed that 97 percent had notable measures of undercarboxylated MGP suggesting vitamin K deficiency or insufficiency. When supplemented with vitamin K there was a significant reduction in undercarboxylated MPG. Furthermore research in healthy adults show that undercarboxylated MPG increase with age with a significant rise seen above age 40. This suggests that vitamin K levels decrease with age. The U.S. Food and Nutrition Board established the adequate intake (AI) levels of vitamin K for adults 19 years and older of 120 mcg day for men and 90 mcg day for women--but this may be inadequate. Research has shown that vitamin K2 (especially MK-7) has advantages of vitamin K1 and that MK-7 is well absorbed. Furthermore research has shown that 180 mcg day of vitamin K2 as MK-7 reduced arterial stiffness (caused by calcification) and decreased the age-related decline in bone mineral content and bone mineral density. Consequently it seems reasonable to suggest that recommendations for vitamin K2 (as MK-7) be increased to 180 mcg day for adults. vitamin K2 although novel anticoagulant (NOAC) drugs may be used concomitantly. Consequently the recommendation of 180 mcg day vitamin K2 as MK-7 is well within safety ranges. References 1 Food and Nutrition Board Institute of Medicine Vitamin K Chapter 5 in Dietary Reference Intakes for Vitamin A Vitamin K Arsenic Boron Chromium Copper Iodine Iron Manganese Molybdenum Nickel Silicon Vanadium and Zinc. National Academy Press Washington District of Columbia USA (2001). 2 Ferland G. The discovery of vitamin K and its clinical applications Ann. Nutr. Metab. 61(3) 213218 (2012). 3 Shearer M.J. Vitamin K Lancet 345(8944) 229-234 (1995). 4 Booth S.L. Vitamin K food composition and dietary intakes Food Nutr. Res. 56 5505 (2012). 5 Maresz K Bruno EJ. Vitamin K2 An Essential Protector for Cardiovascular Health. Agro Food Ind Hi Tech 2015 26(5) 21-24. 6 Geleijnse J.M. Vermeer C. Grobbee D.E. et al. Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease The Rotterdam Study J. Nutr. 134 3100-3105 (2004). 7 Beulens JW Bots ML Atsma F Bartelink ML Prokop M Geleijnse JM Witteman JC Grobbee DE van der Schouw YT. High dietary menaquinone intake is associated with reduced coronary calcification Atherosclerosis 2009 203(2) 489-493. 8 Bruno EJ. The Prevalence of Vitamin K Deficiency Insufficiency and Recommendations for Increased Intake. J Hum Nutr Food Sci. 2016 4(1) 1077. Vitamin K Safety There is no known toxicity associated with high doses of the vitamin K1 or K2 (although the same is not true for synthetic vitamin K3 menadione). Consequently no tolerable upper level (UL) of intake has been established for vitamin K1 or K2 by the Food and Nutrition Board Institute of Medicine or by the World Health Organization. Moreover long-term high dosage therapy with vitamin K is not associated with increased thromboembolic events and no elevated event rate was recorded even with 45 mg (that s milligrams not micrograms) vitamin K2 (MK-4) daily for three years in 2 185 postmenopausal osteoporotic women. Currently vitamin K antagonist medications (i.e. coumarins) are the only contraindications for patients using Gene Bruno MS MHS the dean of academics for Huntington College of Health Sciences is a nutritionist herbalist writer and educator. For more than 30 years he has educated and trained natural product retailers and health care professionals has researched and formulated natural products for dozens of dietary supplement companies and has written articles on nutrition herbal medicine nutraceuticals and integrative health issues for trade consumer magazines and peerreviewed publications. He can be reached at gbruno hchs.edu. MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 41 NATURAL HEALTH STUDIES Adolescents Stress More With Poor Sleep new study from the University of Alabama at Birmingham (UAB) indicates that adolescents who experience sleep problems and longer sleep duration are more reactive to stress which could contribute to academic behavioral and health issues. Existing studies show that nearly 70 percent of U.S. adolescents do not receive sufficient sleep. It is also known that insufficient sleep and sleep problems contribute to cognitive problems and poor physical health over time possibly because of disruptions in a key part of the neuroendocrine system that controls reactions to stress and regulates many body processes-- the hypothalamic-pituitary-adrenal axis or the HPA axis. The relationship between sleep and the HPA axis has been studied in both children and adults but little is known about this link during adolescence which is a key period of time as both sleep and the HPA axis are undergoing significant developmental changes related to puberty. Sylvie Mrug a psychology professor in UAB s College of Arts and Sciences and her colleagues from UAB and Arizona State University sought to further explore the relationship between sleep and reactivity to stress specifically as it relates to HPA-axis activity in adolescents. The researchers examined two dimensions of sleep--sleep duration and sleep problems from the perspectives of adolescents and their parents as well as cortisol levels before and after social stress. The team also looked at how the results varied based on gender. A We chose to look at sleep patterns in urban AfricanAmerican adolescents due to information we understood from earlier research in the field Mrug said. This particular population is more likely to experience insufficient sleep and their functioning is more negatively affected by lower sleep quality so we knew that finding results for this demographic could be especially important. Eighty-four adolescents with an average age of approximately 13 took part in the study. During their visit to the research lab participating adolescents were given the children s version of a common stress test called the Trier Social Stress Test to measure their physiological responses to stress. This test involves speaking and computing mental math problems in front of an audience. Saliva samples were taken from each participant in order to test cortisol levels before and after the stress test. Participants then reported on their bed times and wake times and any sleep problems such as insomnia daytime sleepiness and general sleep quality during a regular week. Parents of the adolescents were asked to report on their children s sleep as well. The adolescents most commonly reported the following sleep problems the need for multiple reminders to get up in the morning not having a good night s sleep feeling tired or sleepy during the day and not being satisfied with their sleep. The researchers looked at the cortisol levels of the adolescent participants. Cortisol release during and after the stressful lab test was higher for adolescents who reported more sleep problems and longer sleep duration and whose parents reported longer sleep duration. The result of higher cortisol levels in adoles- cents experiencing sleep problems was exactly what we expected to see Mrug said. We were however surprised that longer sleep duration predicted a stronger cortisol response because previous studies linked shorter sleep duration with higher cortisol levels. Generally less sleep is related to poor outcomes not the other way around. In this case this unexpected result could be explained by considering that longer sleep duration does not necessarily reflect higher-quality sleep but instead may serve as another indicator of sleep problems at least among urban adolescents. The effects of sleep problems on greater cortisol release during stress were stronger in females than in males suggesting that adolescent girls may be more sensitive to disrupted and poor quality sleep. Overall the results of our study confirm what we originally hypothesized--that sleep problems induce greater response to stress in adolescents Mrug said. It s important that we know this because the enhanced and prolonged activation of the HPA axis in response to stress could contribute to more health problems. The urban African-American youth whom we studied may be particularly negatively affected by poor sleep because they are more likely to experience uncontrollable stress related to community and school violence. We want to do all that we can to understand ways we can help ensure better cognitive emotional and physical health outcomes for these adolescents. (Source Physiology and Behavior-- March 2016) 42 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Meditation Eases Pain Anxiety and Fatigue During Breast Cancer Biopsy M editation eases anxiety fatigue and pain for women undergoing breast cancer biopsies according to researchers at the Duke Cancer Institute. They also found that music is effective but to a lesser extent. The researchers note that adopting these simple inexpensive interventions could be especially helpful in light of recent reports citing anxiety and pain as potential harms from breast cancer screenings and testing. Image-guided needle biopsies for diagnosing breast cancer are very efficient and successful but the anxiety and potential pain can have a negative impact on patient care said Mary Scott Soo MD associate professor of radiology at Duke Cancer Institute and lead author of the study published online in the Journal of the American College of Radiology. Patients who experience pain and anxiety may move during the procedure which can reduce the effectiveness of biopsy or they may not adhere to follow-up screening and testing. She added that the study comes at a time when federal reimbursement requirements are increasingly focusing on patient care and adjusting payments based on patient satisfaction. It s important that we address these issues to provide a better experience and more compassionate care for our patients Dr. Soo said. Dr. Soo and colleagues enrolled 121 women undergoing breast cancer diagnosis at Duke and randomly assigned them to receive one of three approaches as they underwent stereotactic and ultrasound-guided biopsy a recorded meditation music or standard care with a technologist offering casual conversation and support. The meditation was a guided loving kindness script that focused on building positive emotions such as compassion towards oneself and others and releasing negative emotions. Patients in the music group listened to their choice of instrumental jazz classical piano harp and flute nature sounds or world music. Standard-care patients received supportive and comforting dialogue with the radiologist or technologist. Immediately before and after biopsy participants completed questionnaires measuring nervousness and anxiety ranking biopsy pain between a low of zero to a high of 10 and assessing feelings of weakness and fatigue. Patients in the meditation and music groups reported significantly greater reductions in anxiety and fatigue after biopsy than those receiving standard care. The standardcare patients reported increased fatigue after biopsy. The meditation group also showed significantly lower pain during biopsy when compared to the music group. Listening to guided meditation resulted in significantly lower biopsy pain during imaging-guided breast biopsy and both meditation and music reduced patient anxiety and fatigue Dr. Soo said. There are medical approaches to this--providing anti-anxiety drugs--but they sedate patients and require someone to drive them home. Meditation is simple and inexpensive and could be a good alternative in these settings Dr. Soo continued. We would like to see this study scaled up to include a multi-center trial and see if the findings could be generalized to different practices. (Source Journal of the American College of Radiology--February 2016) High Serum Omega-6 PUFA Concentrations Linked to Lower Risk of Type 2 Diabetes A new study from the University of Eastern Finland shows that high serum omega-6 polyunsaturated fatty acid concentrations are linked to a significantly reduced risk of type 2 diabetes. The findings were published in the American Journal of Clinical Nutrition. It has been speculated that a high intake of omega-6 polyunsaturated fatty acids may increase the risk of several chronic diseases as these fatty acids have been suggested to promote low-grade inflammation among other things. However studies conducted on humans have not established a link between even a high intake of omega-6 fatty acids and inflammation. Furthermore omega-6 fatty acids have beneficial effects on for example glucose metabolism. Earlier research has systematically linked especially linoleic acid which is the most common omega-6 fatty acid to a reduced risk of cardiovascular diseases and type 2 diabetes. However scientific evidence relating to the health effects of other omega-6 polyunsaturated fatty acids is not as inconclusive. The serum fatty acid concentrations of 2 189 men aged between 42 and 60 years and with no baseline type 2 diabetes diagnosis were analyzed at the onset of the Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD) in 1984-1989 at the University of Eastern Finland. During a follow-up of 19 years 417 men were diagnosed with type 2 diabetes. The study found that high serum omega-6 polyunsaturated fatty acid concentrations were associated with a 46 percent lower risk of developing type 2 diabetes during the follow-up. When analyzing the independent associations of different omega-6 polyunsaturated fatty acids a similarly significant association was found between high serum linoleic and arachidonic acid concentrations and a lower risk of type 2 diabetes. However high serum gamma-linolenic and dihomo-linolenic acid concentrations were linked to a higher risk. The study indicated that high serum linole- ic and arachidonic acid concentrations are linked to a lower risk of type 2 diabetes. The serum linoleic acid concentration is determined by the person s diet and the main sources of linoleic acid are vegetable oils nuts and seeds. Arachidonic acid is present in meat and eggs however the human body can also make arachidonic acid from linoleic acid. Gamma-linolenic acid and dihomo-linolenic acid are mainly formed in the human body from linoleic acid. Their concentrations in serum are very low in comparison to for example linoleic acid. The association of gamma-linolenic acid and dihomo-linolenic acid with a higher risk of type 2 diabetes has been observed in some earlier studies but the underlying reason remains unknown. All in all however this study as well as several earlier ones suggest that polyunsaturated omega-6 fatty acids have a beneficial impact on the risk of type 2 diabetes. (Source American Journal of Clinical Nutrition--February 2016) MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 43 NATURAL HEALTH STUDIES Adherence to Nutrition Recommendations and Supplements Essential for Vegans egans adhere to nutrition recommendations in varying degrees according to a new Finnish study. Some vegans who participated in the study followed a balanced diet while others had dietary deficiencies. Typical deficiencies were an unbalanced use of protein sources a low intake of berries fruits and nuts as well as failure to use nutrient fortified food products. The majority however used vitamin B12 and D supplements and calciumfortified drinks as recommended. The findings were published in PLOS ONE. The serum vitamin D concentrations were below the reference values in 24 percent of the vegan group. They also had lower concentrations of beta-carotene selenium iodine and essential fatty acids than the control group following a non-vegetarian diet. According to the researchers the findings highlight the need of vegans to get nutrition guidance and to use the recommended nutrient supplements. Moreover closer attention should be paid to the intake of vitamin D and iodine among vegans. Vegetarian and vegan diets are increasingly common in Western societies. However in order to ensure the intake of all the necessary nutrients vegetarian and vegan diets need to be composed in a wellrounded manner. Research into the nutri- V tional status of vegans nevertheless remains scarce. The study analyzed the nutritional status of young adults who had been following a vegan diet for an average period of eight years. The study involved six male vegans and 16 female vegans and the matched control group comprised eight men and 11 women who followed a non-vegetarian diet. The researchers were especially interested in the intake and concentrations of nutrients that are limited or lacking in vegetarian foods for example vitamin B12 vitamin D selenium iodine and essential fatty acids. The food intake of the study participants was analyzed from three-day food records and their nutritional status was measured from blood and urine samples. The diet of the vegan group was exclusively limited to plant-based foods and their intake of legumes tofu and soy flour was higher than the control group s but no other significant differences were observed. Nutrient supplements were used by 91 percent of the vegan group and 78 percent of the control group. Vitamin B12 supplementation was used by 91 percent of the vegan group vitamin D supplementation by 77 percent and the majority also used calcium-fortified drinks. The vitamin B12 concentrations of the vegan group were within the reference values as were the values of the control group. The serum vitamin D concentrations were below the reference values in 24 percent of the vegan group and in 6 percent of the control group. Vegans also had lower concentrations of beta-carotene selenium iodine and the essential EPA and DHA fatty acids. All in all however vegans had higher polyunsaturated fatty acid concentrations and lower saturated fatty acid concentrations than the control group. In addition the concentrations of soy polyphenols were high in vegans. The median concentration of iodine in urine was below the recommended levels in both groups. Earlier research shows that the intake of iodine has decreased in Finland over the past years. Iodine is present in milk and iodine-fortified salt the use of which have declined. (Source PLOS ONE--March 2016) Vitamin D Level Body Fat in Newborn Linked to Health Status in Pregnancy oes a newborn s vitamin D level relate to the mother s weight during pregnancy Results from a study published in PLOS ONE provides ample evidence that yes higher body mass index (BMI) in mothers is associated with lower vitamin D levels in their babies. This is a concern since low vitamin D at birth may be associated with reduced bone mineral density in the long term as well as increased risk of allergic disease and obesity. Our study suggests that overweight or obesity in pregnancy is linked to lower vitamin D levels in both the mother and the newborn said Jami Josefson MD endocrinologist at Ann & Robert H. Lurie Children s Hospital of Chicago and assis- D tant professor at Northwestern University Feinberg School of Medicine. More research is needed however before we can make broad recommendations about the need for greater supplementation of vitamin D for overweight pregnant women. Obesity in pregnancy has become increasingly common. In addition to lower vitamin D levels it has been associated with heavier infants who then are at higher risk for childhood obesity and type 2 diabetes. Currently Dr. Josefson and Wendy Brickman MD also an endocrinologist at Lurie Children s are involved in a follow- up to the large international study that discovered the importance of increased maternal glucose level even when it is not full blown diabetes. It was still associated with higher birth weight and body fat in the newborn. The follow-up study at Lurie Children s and nine other centers around the world sets out to see how those kids and mothers fare eight to 12 years later. These observational studies will help us develop and test targeted interventions so we can provide mothers and children the best opportunities for long-term health said Dr. Josefson. (Source PLOS ONE--March 2016) 44 NATURAL PRACTITIONER WWW.NATURALPRACTITIONERMAG.COM MAY 2016 Use of Mindfulness-based Stress Reduction for Chronic Low Back Pain A mong adults with chronic low back pain both mindfulness-based stress reduction and cognitive behavioral therapy resulted in greater improvement in back pain and functional limitations when compared with usual care according to a study appearing in the journal JAMA. Low back pain is a leading cause of disability in the United States. There is need for treatments with demonstrated effectiveness that are low risk and have potential for widespread availability. Mindfulness-based stress reduction (MBSR) focuses on increasing awareness and acceptance of moment-to-moment experiences including physical discomfort and difficult emotions. Only one large randomized clinical trial has evaluated MBSR for chronic low back pain and that trial was limited to older adults. Daniel C. Cherkin PhD of Group Health Research Institute (Seattle WA) and colleagues randomly assigned 342 adults age 20 to 70 years with chronic low back pain to receive MBSR (n 116) cognitive behavioral therapy (CBT n 113) or usual care (n 113). CBT (training to change pain-related thoughts and behaviors) and MBSR (training in mindfulness meditation and yoga) were delivered in eight weekly two-hour groups. Usual care included whatever other treatment if any the participants received. The average age of the participants was 49 years the average duration of back pain was 7.3 years. The researchers found that at 26 weeks the percentage of participants with clinically meaningful improvement on a measure of functional limitations was higher for those who received MBSR (61 percent) and CBT (58 percent) than for usual care (44 percent). The percentage of participants with clinically meaningful improvement in pain bothersomeness at 26 weeks was 44 percent in the MBSR group and 45 percent in the CBT group vs. 27 percent in the usual care group. Findings for MBSR persisted with little change at 52 weeks for both primary outcomes. The effects were moderate in size which has been typical of evidence-based treatments recommended for chronic low back pain. These benefits are remarkable given that only 51 percent of those randomized to receive MBSR and 57 percent of those randomized to receive CBT attended at least six of the eight sessions the authors wrote. These findings suggest that MBSR may be an effective treatment option for patients with chronic low back pain. Although understanding the specificity of treatment effects mechanisms of action and role of mediators are important issues for researchers they are merely academic for many clinicians and their patients. For patients with chronic painful conditions options are needed to help them live with less pain and disability now wrote Madhav Goyal MD MPH and Jennifer A. Haythornthwaite PhD of Johns Hopkins University School of Medicine (Baltimore MD). The challenge is how to ensure that these mind-body interventions are available given the existing evidence demonstrating they may work for some patients with chronic low back pain. Most physicians encounter numerous obstacles finding appropriate referrals for mind-body therapies that their patients can access and afford. High-quality studies such as the clinical trial by Cherkin et al create a compelling argument for ensuring that an evidence-based health care system should provide access to affordable mind-body therapies. (Source JAMA--March 2016) MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 45 NATURAL MARKETPLACE NATURAL MARKETPLACE PROVIDES INFORMATION ABOUT NEW PRODUCTS AVAILABLE TO THE NATURAL HEALTH CARE INDUSTRY. ALL STATEMENTS CLAIMS AND PRODUCT INFORMATION ARE PROVIDED BY THE MANUFACTURER. NATURAL PRACTITIONER DOES NOT ENDORSE ANY PRODUCTS INCLUDED IN NATURAL MARKETPLACE OR ATTEMPT TO CORROBORATE ANY CLAIMS MADE BY THE MANUFACTURER. To have a new product included in Natural Marketplace please send a press release and photograph to Natural Practitioner by email to ShariB VRMmedia.com Fenugreek PITTSBURGH PA--New from Genestra Brands Fenugreek vegetable capsules provide 2000 mg of fenugreek seed extract per day. Fenugreek seeds help promote healthy glycemic responses by stimulating insulin signaling pathways and promoting glucose uptake in peripheral tissues. Fenugreek seeds support healthy lipid metabolism by promoting cholesterol metabolism and the excretion of bile acids and neutral sterols. Collectively this supports healthy levels of lipids including total cholesterol LDL VLDL and triglycerides. 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MAY 2016 WWW.NATURALPRACTITIONERMAG.COM NATURAL PRACTITIONER 47 CONFERENCES AND EVENTS May 12-14 Institute for Functional Medicine s Annual International Conference (IFM) San Diego CA IFM s 2016 Annual International Conference presents strategies to transform recent scientific findings on the benefits of sleep restoration fitness and movement into actionable prescriptions for health. Learn the skills and science behind new technological tools and clinical innovations that can help patients sleep better relax and increase their activity levels. This year IFM s Annual International Conference is all about how to collaborate with patients to help them see the value in these important lifestyle changes and implement them sustainably. For more information visit www.functionalmedicine.org. May 13-15 17th International Conference on Ayurveda and Foods Pittsburgh PA This conference is open to all integrative health professionals dietitians nutritionists naturopathic doctors chiropractors holistic nurse practitioners ayurvedic and yoga practitioners herbalists massage therapists as well as the general public. Held at the Indian Community Center it offers keynote presentations like Ayurvedic Nutrition Made Simple by Paul Dugliss MD Explore Your Hunger The Story Behind Your Body s Craving for Food by John Immel BS Nutrition Specifics in the Panchakarma in the U.S. by Lina Thakar BAMS and more. For more information visit www.globalayurvedaconferences.com. May 14-15 The 2016 Integrative Medicine Summit New York & Connecticut The 2016 Integrative Medicine Summit will be held in two locations this year on Saturday May 14 the summit will be held in Times Square in New York NY and on Sunday May 15 in Greenwich CT. Hosted by XYMOGEN this unique conference features pioneers in the Integrative and Functional Medicine community. Compelling insights will address many modern epidemics along with innovative solutions and out-ofthe-box approaches. Enjoy a healthy gluten-free lunch and dive into new paradigms in health care treatment. Speakers include Tania Dempsey MD Brian Blackburn founder and CEO of XYMOGEN Frederick Sutter MD Joseph Evans MD among others. For more information visit www.xymogen.com about-us xymogen-events . May 17-20 International Congress on Integrative Medicine and Health Las Vegas NV Held at the Green Valley Ranch Resort Las Vegas NV the International Congress on Integrative Medicine and Health is a comprehensive scientific conference in complementary and integrative medicine. This peer-reviewed scientific meeting includes pre-congress satellites keynote addresses concurrent sessions workshops oral abstract sessions posters experiential sessions and networking opportunities. For more information visit www.ICIMH.org. May 31-June 5 36th Annual American Holistic Nurses Association (AHNA) Bonita Springs FL AHNA s 36th Annual Conference brings together nurses and other health care professionals committed to sharing their experience and expertise in holistic health care. Holistic nurses are driving the paradigm shift locally and globally towards maintaining caring and healing values in the healthcare systems. This conference will explore possibilities for nurses to deepen their influence in all health care settings provide information on the role of nurses in the Affordable Care Act and point to innovative strategies for transforming nursing practice. Topics are diverse and will appeal to nurses who practice in clinical settings education administration and research to those who seek selfcare strategies and personal and professional development. The sessions include offerings at the basic intermediate and advanced level of practice. Registration is open. 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