This Digital Edition requires Flash 9.0.115 or above to activate some rich media components.

Please click the following link to download and install: Get Adobe Flash player
When you are finished installing, please return to this window and PRESS F5 to view this edition.

Description: In This Issue: Figuring Out Fertility, Minerals, Weight Management and Science of Supplements ww Ne V w. w isit Vit W O am eb ur inR si eta te ile r.c om Go to nahs for info about this advertiser Go to wakunaga for info about this advertiser Go to naturesplus for info about this advertiser d o ou ter Pr or p up S f TABLEOFCONTENTS MAY15 VOLUME 22 NUMBER 5 30 36 41 57 Features 30 Figuring Out Fertility The changing market now includes men s supplements age-specific supplements and gummies. Columns 6 Off the Cuff 57 Health & Nutrition 60 Healthy Shopper 61 Product Spotlight 62 Supplement Science 64 Natural Medicine 36 Essential Minerals While vitamins continue to grab headlines the need for minerals is also vital to good health. 41 Science of Supplements Summer Issue This special section delivers important information about the products retailers are selling and demonstrates the science that backs their effectiveness. Copyright 2015. Vitamin Retailer (ISSN 1537-503x & USPS 0019-972) Volume 22 Number 5 May 2015. Vitamin Retailer is published monthly and twice in October by Vitamin Retailer Magazine Inc. 431 Cranbury Road Suite C East Brunswick NJ 08816 USA Phone (732) 432-9600 Fax (732) 432-9288. All rights reserved including the right to reproduce in whole or in part. Not responsible for unsolicited material. Opinions expressed in by-lined articles or advertisements are not necessarily those of Vitamin Retailer or its owners. Publisher is not liable for advertiser product claims or representations. Advertisers assume total responsibility for the contents of their advertisements. Printed in U.S.A. Basic annual subscription rate is 60.00. Periodicals postage paid at East Brunswick NJ 08816 and additional mailing offices. POSTMASTER Send all UAA to CFS. NON-POSTAL AND MILITARY FACILITIES send address corrections to Vitamin Retailer P.O. Box 15186 North Hollywood CA 91615-5186. Subscription Customer Service Vitamin Retailer P.O. Box 15186 North Hollywood CA 91615-5186 USA Phone (818) 286-3168 Fax (800) 869-0040 vrecs Back Issues & Single Copies For order information contact (732) 432-9600 or general August issue is 25.00. October November issue is 45.00. All other issues are 8.00 each. Departments 8 Hot Sellers 10 Behind the Counter 12 Trending Now 14 Industry News 20 NPA Update 22 Expo West Wrap-up 26 Research Update 28 Retail Fundamentals 65 New Products 67 Advertiser Index 68 Back Talk WWW.VITAMINRETAILER.COM MAY 2015 Visit FreeProductInfo for FREE Product Information or Samples from All Vitamin Retailer Advertisers vitaminretailermagazine Also Sign Up for the FREE E-newsletter 4 VITAMIN RETAILER Go to xlear for info about this advertiser OFFTHECUFF The Beat Goes On ust how much longer will the dietary supplement industry continue to be under attack And more importantly has the damage already been done It s been nearly three months since New York Attorney General Eric Schneiderman launched his investigation into the dietary supplements industry by issuing cease-and-desist letters to four major retailers--GNC Target Walgreens and Walmart--calling on them to pull their own brands of herbal supplements from their shelves following an investigation by his office that found nearly 80 percent of the products tested from those stores contained none of the plants listed on the products labels. GNC as you may know (see news update on page 15) reached an agreement with the attorney general s office in late March whereby the company will use DNA tests to authenticate the plants that will be used as ingredients in its herbal supplements. Some industry experts applauded the agreement while others said it set a dangerous precedent going forward. Of course the questionable DNA testing methods used have come under harsh scrutiny by the likes of the Natural Products Association (NPA) the Council for Responsible Nutrition (CRN) and other industry groups but that didn t prevent Schneiderman and 13 other state attorneys general from sending a letter to Congress requesting an investigation into herbal supplements and calling for more regulatory oversight of the industry by the Food and Drug Administration (FDA). Schneiderman and his counterparts despite admitting that the federal good manufacturing practices currently in place for dietary supplements are sufficient continues to push forward in what is seemingly becoming a witch hunt at the expense of taxpayer dollars. 1994 ea t ng 20 Y CelebraEixcellence f o rs 2014 J While the two sides continue to slug it out and the NPA calling for a grassroots campaign to attempt to prevent Schneiderman from taking further action a larger question for the industry at-large may be Has the damage already been done While little has yet to be determined legally regarding the outcome of the dispute the danger here for the dietary supplement industry is that in the court of public opinion they may have already lost. Of course a Harvard-led study early last month that indicated that a handful of weight-loss and sports supplements contained amphetamine-like ingredients not the plant extract listed on the label of the product didn t help the cause. For those who have long supported the dietary supplement industry not much will change. Natural products manufacturers suppliers and retailers alike will strongly defend the methods used to test and regulate their industry and will continue to fight for its survival. On the other hand those who have long opposed or questioned the industry now have more ammunition at their disposal to challenge every move the industry makes. And finally the real danger here is in convincing those consumers who have long been considering walking into your store to try a natural remedy or supplement might now be turned off by the ongoing negative press. So what s the next step Will the letter to Congress sent by Schneiderman and the 13 other state attorneys general be enough to eventually push the industry under regulation by the federal government Does DSHEA carry no weight here For now the smart move for the dietary supplement industry is to continue to provide the quality products that it s always provided. I also encourage you to take part in NPA s grassroots campaign and to join in fighting the good fight. Publisher Daniel McSweeney Editorial Director DanM Associate Russ Fields Publisher RussF Advertising Roy Kieffer Sales Manager RoyK Advertising Gary Pfaff Sales Associate GaryP Editor-in-Chief Daniel Breeman DanielB Managing Editor Janet Poveromo JanetP Associate Shari Barbanel Editor ShariB Assistant Cristina Goodwin Editor CristinaG Art Director Robert Certo Production Manager RobertC Production Assistant Bryan Zak Graphic Designer BryanZ Contributing Writers Gene Bruno MS MHS Debby Swoboda Mayhew Michael T. Murray ND Cheryl Myers Circulation Rosie Brodsky Manager Rosie VRM Media Phone Fax E-mail Website President 431 Cranbury Road Ste. C East Brunswick NJ 08816 (732) 432-9600 (732) 432-9288 info Daniel McSweeney DanM information for and about the dietary supplement industry in order to foster industry growth and help preserve the rights of dietary supplement suppliers and retailers. Subscription Customer Service To order a subscription or manage your account please contact us at Vitamin Retailer P.O. Box 15186 North Hollywood CA 91615-5186 USA Phone (818) 286-3168 Fax (800) 869-0040 vrecs Mission Vitamin Retailer magazine Statement is dedicated to providing Connect With Us Back Issues See the Table of Contents page for price and order information. vitaminretailer vitaminretailermagazine company vrm-media vitaminretailermagazine vrm_media 6 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 Go to reddremedies for info about this advertiser HOTSELLERS Hot Sellers is a monthly what s hot at retail snapshot of six categories of products sold in health food stores across the U.S. by region provided by a rotating Retailer Advisory Board of participating stores. NORTHEAST SOUTHEAST PERELANDRA NATURAL FOOD CENTER Brooklyn NY VITAMIN MINERAL SUPPLEMENT Natural Calm by Natural Vitality SPECIALTY SUPPLEMENT MegaFlora by MegaFood HERBS BOTANTICALS Tumeric Supreme by Gaia Herbs FUNCTIONAL FOOD BEVERAGE Organic Hemp Protein by Nutiva PERSONAL CARE Coco Castile Bar Soap by Kirk s Original HOT PRODUCT OF THE MONTH Rosehip Seed Oil by Aura Cacia FRESH VITAMINS Peachtree City GA VITAMIN MINERAL SUPPLEMENT Every Women s One Daily Multi by New Chapter SPECIALTY SUPPLEMENT Curamin Extra Strength by Terry Naturally HERBS BOTANTICALS Ashwagandha by Ruved FUNCTIONAL FOOD BEVERAGE Green Tea Kombucha by Yogi PERSONAL CARE Collagen Hydra Protect with Ceramides by Reserveage HOT PRODUCT OF THE MONTH Rosehip Oil by Life Flo MIDWEST ANN S HEALTH FOOD CENTER & MARKET Waxahachie TX CENTRAL APPLE TREE NATURAL FOODS Alcoa TN VITAMIN MINERAL SUPPLEMENT Every Woman s One Daily Multi by New Chapter SPECIALTY SUPPLEMENT At Ease by Redd Remedies HERBS BOTANTICALS Cinnamon Force by New Chapter VITAMIN MINERAL SUPPLEMENT Ultimate Omega D3 by Nordic Naturals SPECIALTY SUPPLEMENT Multivitamins by Life s Fortune HERBS BOTANTICALS Milk Thistle by Eclectic Institute FUNCTIONAL FOOD BEVERAGE Coconut Oil by Dr. Bronners PERSONAL CARE Clear the Air essential oil blend by NOW Foods HOT PRODUCT OF THE MONTH Dr. Ohirras Professional Formula FUNCTIONAL FOOD BEVERAGE Synergy by Kombucha PERSONAL CARE Essential Oils by NOW Foods HOT PRODUCT OF THE MONTH Omega Swirl by Barlean s NORTHWEST WEST COUNTRY AIRE NATURAL FOODS Port Angeles WA VITAMIN MINERAL SUPPLEMENT Tumeric by New Chapter SPECIALTY SUPPLEMENT Emu Oil by Montana HERBS BOTANTICALS Curcumin by Jarrow Formulas FUNCTIONAL FOOD BEVERAGE Gluten Free Bread by Udi s PERSONAL CARE Lavender Spritzer by Purple Haze HOT PRODUCT OF THE MONTH Lotion by Nature s Gate SHIRLYN S NATURAL Sandy UT VITAMIN MINERAL SUPPLEMENT mykind Multivitamin by Garden of Life SPECIALTY SUPPLEMENT mykind Organics Plant Calcium by Garden of Life HERBS BOTANTICALS Loose Mullein Leaf FUNCTIONAL FOOD BEVERAGE Coconut Oil PERSONAL CARE Age Defining Therapy by Aubrey HOT PRODUCT OF THE MONTH Curamin by Terry Naturally Retailers interested in having their stores featured in Hot Sellers can visit hotsellers. 8 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 Go to nordicnaturals for info about this advertiser BEHINDTHECOUNTER Behind the Counter is a monthly column profiling successful natural product retailers. New York City s Vibrant Oasis HIGH VIBE (NEW YORK NY) I t was to fulfill his unmet wish for top quality raw foods and food-based supplement products that led Robert (Bob) Dagger in 1993 to open New York Citybased High Vibe a retreat from the relentless hustle and bustle of NYC. The owner a nutritionist never planned to open a health food store he was and still is quite happy making a second living in the art and music world. We couldn t find a store that had 100 percent raw food-based supplements and vitamins and all the items needed to maintain a raw plant-based diet Dagger said. So I decided one was needed and High Vibe was born which explains why their tagline reads As Raw as You Wanna Be. High Vibe is an oasis he said. When stepping into his store customers are welcomed by his personal and ever changing vibrant display of tropical plants and flowers. The touch of greenery works to create a positive comforting and healthy high vibe --so all concerned staff and guests will know and feel they re in a special place the owner explained. Located in Manhattan s East Village neighborhood the small shop offers a very large selection of premium dry fruits raw nuts and seeds raw cacao products coconut products super foods and prepacked vegan raw food products--both sweet and savory. Sun-dried olives lowtemperature processed olive oils cultured nut cheeses and a variety of gluten-free snacks are also available as well as the very best in plant-based vitamins vegan beauty products and health-related books. The vast majority of our merchandise is raw and organic--a 440-squarefoot sanctuary of goodness he said. Next to the variety of supplement brands customers will also find a selection of 70 privately labeled products with two levels of branding. One is under the umbrella of the mother High Vibe brand and the unparalleled High Vibe created by Bob Dagger line he explained. Anytime a cusTHE GO TO RESOURCE FOR HEALTH tomer sees created by or sourced by AND NATURAL PRODUCT RETAILERS Bob Dagger on one LIKE US ON of our High Vibe products they know my thoughts and expertise have gone into the creation of these highly successful formulas. VR s Upcoming The retailer s supplements are beginIssue Highlights ning to be sold in stores around the 6 5 15 Product Sales Training for Retailers world according to July Free submission for all full and half page advertisers. ad closing Dagger. The bestsellers are 7 2 15 August ad closing 2015 Retailer of the Year Omnizimes a highly potent enzymatic blend and Shine Our 2015 Media Planner Is Now Available At the retailer s flagship 2015-Media-Planner MSM-based beauty formulation. Dagger said he created the Contact One of Our enzyme product Ad Specialists Today because like his Russ Fields at 732-432-9600 ext. 102 idea for the raw e-Mail RussF food store he couldn t find a high Roy Kieffer at 719-358-9838 e-Mail RoyK quality enzyme at an Gary Pfaff at 732-432-9600 ext. 107 affordable price. The e-Mail GaryP Shine products were made for a former girlfriend who was looking for internal and external beauty products that worked. Because High Vibe has a limited amount of space Dagger said he is careful to fill the shelves with items that fit the store s philosophy. We only carry the brands that we personally trust we never sell we educate he said. Our customer s are very smart and savvy and know we are looking out for their best interests their trust in us in renewed with every visit. High Vibe also provides customers with a mail order service. It offers free shipping within the U.S. on non-perishable goods for orders over 49. We enjoy serving people in our store by phone order and via our website. The website consistently provides Dagger s store with a 15 percent yearly growth. Our competition usually comes from online stores often operating with low overheads. They can dominate through pure price-cutting he said. However Dagger said he believes that it is his intimate and hands-on approach makes him buoyant and relevant in the ever-changing raw food market. In addition to the online store the website offers an array of recipes that are divided up by category such as Boutenko recipes (from a family of raw food enthusiasts) and Detox Cleansing flushes. Customers are also encouraged to register for High Vibe Health & Healing s educational classes held by Dagger who provides New Yorkers with simple and effective ways to incorporate more healthiness into their life. Topics include detoxing and nutritional fasting natural weight control increasing energy pH balance and more. With a combination of raw foods blended foods exercise stress reduction detoxification supplements and (most importantly) education and responsibility Dagger said his clients have passed from disease and discontent into health vitality and awareness. WWW.VITAMINRETAILER.COM MAY 2015 10 VITAMIN RETAILER Go to rainbowlight for info about this advertiser TRENDINGNOW Seeing Clearly With Lutein & Zeaxanthin BY SHARI BARBANEL the leading cause of vision loss in America for people 65 and older. Further AMD is the leading cause of blindness in people over age 55 in the Western world and the incidence is expected to triple by 2025. Lutein and zeaxanthin are naturally occurring carotenoid compounds that have antioxidant properties that help protect the body from being damaged by free radicals. Found in high concentrations in the macula of the eye lutein and zeaxanthin are responsible for giving it its yellow color. According to the macula is responsible of the eye s central sharp vision which is needed for reading and driving. Retailer Jason Bander of Lifethyme Natural Market in New York NY explained that most people use lutein and zeaxanthin for general eye health but whenever customers are diagnosed with macular degeneration of the eye these two carotenoids help to maintain the structure of the macula. The macula or macula lutea is an oval shaped pigmented area near the center of the light sensitive retina of the eye he continued. Zeaxanthin is the most abundant pigment in the central macula lutein more dominant in the periphery of the retina. Research has shown that both lutein and zeaxanthin are beneficial for maintaining eye health. In fact according to a 2007 study published in the journal Archives of Opthamology researchers looked at the effect of carotenoids on AMD. They found that a diet high in carotenoids was associated with a low risk for the disease. The researchers also noted that among the certain carotenoids specifically lutein and zeaxanthin were strongly associated with a reduced risk for AMD. Additionally the results from the AgeRelated Eye Disease Study 2 (AREDS2) which were published in 2013 in the journals JAMA and JAMA Ophthalmology found that for those individuals in the lowest quintile of dietary intakes of lutein and zeaxanthin--supplementing with lutein and zeaxanthin showed a 26 percent decrease in advanced AMD progression a 36 percent reduction in risk for severe cataracts and a 32 percent reduction for progression to cataract surgery. Lutein and zeaxanthin are an all-natural support for preventing vision loss and lowering risk of eye diseases said Fred Evaristo owner of Freddie s Nutrition which has two locations in Las Vegas NV. Lutein and zeaxanthin have been clinically shown to prevent macular degeneration and support vision especially in senior citizens. For this reason both lutein and zeaxanthin have become hot commodities for natural health retailers. Bander noted that lutein and zeaxanthin are very popular at Lifethyme Natural Market. Most customers are always reminded of health maintenance issues and at most times are very well educated by their physicians and our staff he said. They are always aware that the loss of vision and other issues of aging remain well within the forefront of their everyday lives. We have a wide selection ranging from simple lutein and zeaxanthin with no other ingredients to eye health formulas that feature lutein and zeaxanthin along with other ingredients for visual support added Evaristo. The American Optometric Association noted that while there is no recommended daily intake for lutein and zeaxanthin most recent studies show a health benefit for lutein supplementation at 10 mg day and 2 mg day for zeaxanthin. VR WWW.VITAMINRETAILER.COM MAY 2015 he ability to see is something that a number of us take for granted. But those with vision problems would do just about anything to be able to view to the world clearly. According to the American Foundation for the Blind a rapidly increasing proportion of the aging population experiences eye problems that make simple daily tasks difficult or impossible even when wearing glasses or contact lenses. As people age they are far more likely to have serious agerelated eye conditions--problems with the eyes and vision have been found to significantly increase especially for those over the age of 65. Further according to Prevent Blindness America the four leading eye diseases affecting older Americans are age-related macular degeneration (AMD) cataracts diabetic retinopathy and glaucoma. Lutein and zeaxanthin have garnered a lot of attention by consumers for their eye health benefits. Found in eggs and leafy green vegetables among other foods studies have shown that lutein and zeaxanthin can help reduce the risk of chronic eye diseases such as cataracts and AMD. According the American Optometric Association incidences of AMD and cataracts are growing. More than 25 million people are affected by AMD and the formation of cataracts worldwide and it is T 12 VITAMIN RETAILER Go to essentialformulas for info about this advertiser INDUSTRYNEWS Got News Send news press releases to Editor Vitamin Retailer 431 Cranbury Road Ste. C East Brunswick NJ 08816 DanielB Industry Mourns the Loss of Gerald Kessler erald Kessler a natural products industry leader and founder of Nature s Plus and Natural Organics Inc. (Melville NY) passed away recently at the age of 80. His funeral service took place on March 25 at Loper Funeral Chapel in Solvang CA. Kessler who was known as an industry innovator also helped shape and pass the Dietary Supplement Health and Education Act (DSHEA) in 1994. After graduating from New York University (NYU) he spent 14 years as a G sales representative for various pharmaceutical companies where he learned about the benefits of vitamins and supplements which gave him the idea for Nature s Plus. Over the course of 40 years he developed more than 1 000 Nature s Plus products and was a champion for the industry. More recently he founded a movie studio GruntWorks Entertainment and produced directed and acted in several feature films. His family and friends issued a statement describing him as a giant of a man in stature heart and soul who dedicated his entire life to continually supporting the wellness of millions of consumers worldwide. Industry Associations Comment on BMPEA Actions he Natural Products Association (NPA) CEO and Executive Director Daniel Fabricant PhD commented on Sen. Chuck Schumer s (D-N.Y.) call for the FDA to ban any product containing BMPEA a substance similar to amphetamine after reports that the ingredient was found in dietary supplements. The Natural Products Association strongly believes that banning products containing BMPEA is an unrealistic way for the FDA to remove them from store shelves and is a waste of the agency s time and resources Fabricant stated. The proposed ban is not based in the reality of how food and drug law actually works. The agency has several stronger and quicker tools it can rely on to go after products that it feels pose a threat to consumers including mandatory recall authority and administrative detention. What s more the FDA has the necessary expertise on staff to determine whether BMPEA is dangerous and if and how it should be removed from the marketplace. While many have questioned whether BMPEA is a legitimate dietary ingredient that decision is ultimately up to the FDA and the agency can use its power to take action against companies that have not filed new dietary ingredient notifications (NDIs). The FDA has T always had full regulatory authority over dietary supplements and protecting public health is at the forefront of its mission. NPA supports FDA exercising its full regulatory authority under the law if it finds valid safety concerns with certain products. The Council for Responsible Nutrition (CRN) also issued a statement by Steve Mister president & CEO in response to an article An amphetamine isomer whose efficacy and safety in humans has never been studied methylphenylethylamine (BMPEA) is found in multiple dietary supplements published online in Drug Testing and Analysis. We share the concerns of Dr. Pieter Cohen and his study co-authors regarding BMPEA an amphetamine isomer stimulant that should not be used in dietary supplement products because it is a synthetic drug-like substance not a dietary ingredient Mister stated. The Food and Drug Administration (FDA) first raised the issue of Acacia rigidula supplements adulterated with BMPEA in an article published by the agency in 2014 in the Journal of Pharmaceutical and Biomedical Analysis noting that the amine compound is not found in the Acacia rigidula plant. We urge FDA to take immediate enforcement action against these adulterated products containing BMPEA and the companies illegally spiking these products with this synthetic drug Mister continued. BMPEA does not appear to be a legitimate dietary ingredient and therefore its inclusion in a product labeled as a dietary supplement makes the product adulterated under the Dietary Supplement Health & Education Act (DSHEA). Under the law the agency can demand a product recall for potential safety concerns. It can also declare these products misbranded because synthetic BMPEA was not listed on the labels or proclaim they are adulterated for the simple fact that there has been no pre-market notification submitted for BMPEA as required by law... Although Acacia rigidula supplements represent a very small portion of the dietary supplement industry--so small that we are not aware of specific sales data--FDA has the tools it needs under the law to take action before there are serious health consequences and CRN is asking the agency to do just that. For more information call (202) 204-7700 or visit or 14 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 GNC Makes Deal with NY Attorney General n March 30 GNC (Pittsburgh PA) announced that it had reached an agreement with the New York Attorney General (NYAG) that affirms the company s Herbal Plus products were in full compliance with the federal U.S. Food and Drug Administration (FDA) current good manufacturing practice (cGMP) requirements and acknowledges GNC s full cooperation with the AG s inquiries. In its response to the NYAG s inquiry GNC provided the results of rigorous tests conducted both internally and by independent third parties. These tests provided conclusive evidence that GNC s products are safe pure properly labeled and in full compliance with all regulatory requirements. The testing also demonstrated that the company s products contain all herbal extracts listed on their respective labels. In addition a former senior FDA cGMP expert performed a comprehensive review of GNC s manufacturing processes for the products at issue and found them to be in compliance with all applicable requirements. Accordingly GNC has O restored its full assortment of Herbal Plus products to all GNC stores in New York State. GNC also announced that it will expand its testing processes deeper into its supply chain by leading ongoing industry efforts to integrate source material traceability standards including DNA barcoding where appropriate (prior to extraction processes) and enhance certain other aspects of its operations to provide consumers even greater confidence in its products. GNC said that it believes these measures which would not have impacted availability of the products subject to this review will result in the adoption of stricter minimum standards across the broader industry. As our testing demonstrated and this agreement affirms beyond any doubt our products are not only safe and pure but are in full compliance with all regulatory requirements said Michael G. Archbold CEO GNC. A robust testing regime careful sourcing regimen and detailed manufacturing specifications have always been core elements to ensuring that we provide our customers with high-quality products. Our customers trust and value our products and we are steadfastly committed to maintaining that trust and confidence. As an industry leader we have always gone above and beyond the minimum requirements in pursuing quality for our consumers and we will continue to lead the efforts for higher standards. This is good for consumers good for the industry and good for GNC. GNC has preserved the specific product lots of the five products that were the subject of the NYAG inquiry for use in defending the Company against the lawsuits that have been filed subsequent to the NY AG s February 2 letter despite the fact that there is no prohibition against the sale of such products. GNC believes these lawsuits are completely without merit and will defend itself aggressively. Identical products to those that have been preserved remain available for sale to consumers at GNC stores in New York State. For more information visit Go to hyalogic for info about this advertiser MAY 2015 WWW.VITAMINRETAILER.COM VITAMIN RETAILER 15 INDUSTRYNEWS AHPA Presents Overview of Supplement Regulations at ASA Conference merican Herbal Products Association (AHPA) President Michael McGuffin presented an overview of the federal regulations for herbal dietary supplements at the Americans for Safe Access (ASA) National Unity Conference on March 29 in Washington D.C. The presentation was part of a panel discussion that examined the A implications of several possible regulatory schemes for cannabis products. McGuffin provided an overview of many aspects of federal regulations for supplements including mandatory manufacturing facility registration allowed ingredients in dietary supplements the forms of dietary supplements NDIs (new dietary ingredients) labeling requirements and advertising claims and current good manufacturing practice (cGMP) requirements. McGuffin also reviewed six warning letters the Food and Drug Administration (FDA) recently sent to companies marketing products with the ingredient cannabidiol (CBD). The warning letters focused on claims made by the companies that promoted the products for conditions that caused the products to be drugs. However the FDA did not say the ingredient is unlawful or an NDI. Go to capsugel for info about this advertiser 16 VITAMIN RETAILER While it is interesting that FDA did not address the legal or NDI status of CBD in the warning letters this doesn t mean that FDA has determined that these ingredients are legal or old dietary ingredients McGuffin said. Regarding NDIs McGuffin noted that companies are required to provide FDA with premarket notification including information that is the basis for the manufacturer or distributor concluding that a dietary supplement containing the NDI will reasonably be expected to be safe. McGuffin also provided an overview of cGMP regulations for dietary supplements and noted that these regulations were the primary reference used to create AHPA s Recommendation for Regulators on Cannabis Manufacturing Packaging Labeling and Holding Operations. For more information call (301) 588-1171 or visit WWW.VITAMINRETAILER.COM MAY 2015 Sprouts Announces Expansion Plans rizona-based Sprouts Farmers Market one of the fastestgrowing retailers in the country recently announced plans to add eight additional locations to its growing roster of fresh natural and organic grocery stores. Sprouts stores scheduled to open in the third quarter of 2015 include Denver CO 197 E. Mississippi Ave. Fort Worth TX - 6300 Waverly Way Germantown TN - 3150 Village Shops Dr. 105 Lawrence KS - 4740 Bauer Farm Dr. Pearland TX - 2718 Old Chocolate Bayou Rd. Roswell GA - 10800 Alpharetta Hwy. Ste. C-410 Rowlett TX - Texas 66 & Rowlett Road Sandy Springs GA - 4600 Roswell Rd. A100. A and supplements and more. Shoppers will find a selection of fresh fruits and vegetables and barrels of grains nuts and sweets. The bright open stores showcase fresh-baked goods beer and wine and thousands of natural organic and gluten-free groceries. Sprouts on-site butchers help customers with special cuts of meat or seafood or handmade burgers and sausages. The vitamin department carries thousands of vitamins natural remedies functional food lifestyle support and herbal supplements. For more information call (480) 814-8016 or visit Each of these stores will bring an estimated 100 jobs to the communities in which they are opening. Grand opening dates and other details will be shared in mid2015. Twenty new stores either have opened or are scheduled to do so in the first half of the year. According to the company Sprouts offers consumers a complete healthy grocery store experience featuring fresh produce bulk foods dairy meat and seafood bakery vitamins Go to frey for info about this advertiser MAY 2015 WWW.VITAMINRETAILER.COM VITAMIN RETAILER 17 INDUSTRYNEWS WHO Releases Guidelines to Reduce Sugar Intake new World Health Organization (WHO) guideline released in March recommends adults and children reduce their daily intake of free sugars to less than 10 percent of their total energy intake. A further reduction to below 5 percent or roughly 25 grams (6 teaspoons) daily would provide additional health benefits the WHO said. Free sugars refer to monosaccharides (such as glucose fructose) and disaccharides (such as sucrose or table sugar) added to foods and drinks by the manufacturer cook or consumer and sugars naturally present in honey syrups fruit juices and fruit juice concentrates. According to Dr. Francesco Branca director of WHO s Department of Nutrition for Health and Development Making policy changes to support this will be key if countries are to live up to their commitments to reduce the burden of non-communicable A diseases. Australia s Obesity Policy Coalition said that the release of the WHO s guidelines around sugar has prompted a coalition of leading health organizations to call for a national strategy around obesity that includes policies to directly impact the amount of added sugars. In the U.S the Centre for Science in the Public Interest (CSPI) said that on the report of the Dietary Guidelines Advisory Committee that it s mostly unchanged from the reports of 2010 and years past but that the changes are mostly for the better such as limiting added sugars. The committee has stated that a sustainable diet higher in plantbased foods and lower in animal- based foods is better for both our health and the planet than the current American diet said CSPI executive director Michael F. Jacobson. For more information call 41 22 791 21 11 or visit You re Hired derma e announced two new hires to its external training team Camille Morgan as Western regional trainer and Mary Brennen as Central regional trainer. In their new roles Morgan and Brennen will foster broader deeper education programs to promote the superior quality and efficacy of the derma e natural product line. 18 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 Go to taiyo for info about this advertiser NPAUPDATE Leading Industry Association Speaks Directly to Vitamin Retailer s Readers Ensure Your Customers Know the Facts about Supplements N ew York Attorney General (NYAG) Eric Schneiderman has shown no signs of letting up in his assault on the herbal supplement industry. His quest to portray the industry as unregulated and unsafe has expanded to other states and media outlets all across the country. The Natural Products Association (NPA) has heard from many retailers that customers are inquiring about the attorney general s investigation and what it means for the products they rely on each day to benefit their health and wellness. NPA has put together helpful talking points to share with your customers to better educate them on this issue and make them aware that their supplements have always been and will continue to be safe and effective. go unchecked the way in which you buy goods in this country could be significantly impacted. Do you want your choices as a consumer to be curtailed in this manner If the answer is no then you must take action now. Q Is there something wrong with herbal supplements based upon the NYAG s findings No. The NYAG s argument is based on flawed science and application of a method that is not fitfor-purpose. There s no evidence to suggest that these products are harmful or non-compliant with federal laws. All of the botanical dietary ingredients that are the subject of the NYAG s investigation have a long history of use and a strong library of research data supporting their health benefits. Dietary supplement regulations are also in place to ensure the products are manufactured to high quality regarding their composition strength identity and purity and are free of contaminants. Dietary supplements are the only commodity of foods that has a 100 percent mandatory requirement for reporting serious adverse event reports (AERs) to the U.S. Food and Drug Administration (FDA). The agency monitors every single AER for safety issues and uses the reports to remove supplements found to be unsafe from store shelves request a voluntary recall force a mandatory recall or seize products found to be non-compliant with federal laws. Q Are dietary supplements regulated and who regulates them For more than 20 years the FDA has had full regulatory authority and oversight of dietary supplement quality safety and labeling. The Dietary Supplement Health and Education Act of 1994 authorized the FDA to issue regulations to cover all aspects of supplement manufacturing. State attorneys general on the other hand do not have the authority to pull supplements from shelves whereas the FDA is fully equipped to go after dietary supplement manufacturers who do not play by the rules. Since that is not the case here the FDA has not pursued action against any of the manufacturers in question. Q How can this affect you and your dietary supplements The actions and misinformation started by the NYAG has already spread to other states including the attorneys general in Indiana Connecticut the District of Columbia Hawaii Idaho Iowa Kentucky Massachusetts Mississippi New Hampshire Pennsylvania Rhode Island and the Northern Mariana Islands. The attorneys general from these states recently sent a letter to Congress asking them to investigate the supplement industry and expand the FDA s regulatory authority over supplements. Allowing state attorneys general to pull products off shelves without proper regulatory authority sets a dangerous precedent which is a threat across all industries and significantly impacts consumer choice. Q What can you do Consumers must become active in the Natural Products Association s grassroots efforts and prevent officials from removing products especially without sharing the scientific basis for those requests. We must work together--by emailing calling and tweeting--to compel the New York attorney general to share his data and encourage the other attorneys general to rethink their involvement in Attorney General Schneiderman s actions. To participate visit grassrootsaction Dietary supplements are a safe part of a balanced approach to a healthy lifestyle including good diet and exercise. Always consult with your doctor or health care professional before making any changes to your health care regimen. New York Attorney General and Herbal Supplements What Consumers Need to Know Q What is the situation involving the NYAG and herbal supplements In February NYAG Eric Schneiderman sent cease-and-desist letters to four major retailers requesting they remove herbal supplements from store shelves after DNA barcoding tests found products supposedly contained DNA that was either unrecognizable or from a plant other than what was claimed on the label. However the study methodology used by the AG is not fit-for-purpose in testing herbal supplements and he has since allowed one of the retailers to return the exact same products to its shelves after reaching an agreement with the company regarding product testing. But even this has not stopped the NYAG from moving forward with his investigation including sending a letter to Congress requesting it devote time and taxpayer dollars to the matter or releasing his study data which would help better understand exactly what was studied and how. The AG is denying consumers access to goods based on reasoning that would not hold up under public scrutiny. If this situation continues to 20 VITAMIN RETAILER Dan Fabricant PhD Executive Director and CEO Natural Products Association WWW.VITAMINRETAILER.COM MAY 2015 Go to nowsolutions for info about this advertiser EXPOWESTWRAPUP 35 Expo West th Celebrates Growth Anniversaries N atural Products Expo West the world s largest natural organic and healthy products event celebrated its 35th anniversary in grand style in Anaheim CA in March by setting new attendance records. The annual event which brought together more than 71 000 industry members 2 700 exhibiting companies and 634 first-time exhibitors grew 7.2 percent continuing a year-by-year upward climb. Expo West held at the Anaheim Convention Center is co-located with Engredea the event to source new ingredients packaging technologies equipment and services for cuttingedge products and the Fresh Ideas Organic Marketplace an innovative outdoor event that combines a traditional farmers market feel with the businessbuilding power of a trade show. This year the conference program was extended to four days for the first time. The program offered a full array of education topics as well as keynote presentations from Mark Bittman food journalist at The New York Times and Dr. David Perlmutter MD FACN ABIHM board-certified neurologist fellow of the American College of Nutrition who spoke on The Gut of Brain Matters. Bittman s presentation addressed the concerns consumers have about what they should and should not be digesting. If grandma says what is that you know to steer clear he explained. He picked apart real food versus nonreal food attacked the current state of GMO s and how many consumer health fanatics can t even put a finger on what GMO s are and provided his thoughts on today s food pyramid. Perlmutter s presentation explored how the gut and the brain work hand-inhand and specifically how gut bacteria affects the nervous system by creating 22 VITAMIN RETAILER neurotransmitters that help support brain activity. Toward the end of the session he offered natural health retailers pointers on how to educate customers. Happy Anniversary Among the companies commemorating milestones on the show floor at Expo West was Nordic Naturals which celebrated its 20th anniversary with an array of events at its booth and a special voyage for some of its retail partners. Among the numerous festivities Nordic Naturals hosted on the show floor for retailers were special prize giveaways for those who participated in the company s in-booth contests birthday photos where attendees could dress up in party hats and be seen streaming onscreen in the booth gold top hat giveaways and a Slam Dunk basketball shoot contest. Nordic Naturals CEO and Founder Joar Opheim also sponsored an evening cruise around Marina Del Rey Harbor for retailers to celebrate 20 years of success and partnership. Based on a Roaring 20s theme the evening featured music dancing drinks games and entertainment aboard the Fantasea One Yacht Charter. Also celebrating an anniversary at Expo West was Carlson Laboratories which used the trade show to celebrate a half-century of offering high- quality vitamin E nutritional products and arranged a lineup of guest speakers at its booth who support the company s vision. Among the special guest speakers was Jacob Teitelbaum MD a boardcertified internist and leading researcher in the field of chronic fatigue and fibromyalgia who offered signed copies of his book From Fatigued to Fantastic. Alex Richardson MD founder and trustee of FAB Research and senior research fellow at the University of Oxford presented a lecture Changing Diets Changing Minds The Importance of Nutrition for Behavior Learning and Mood and also held a signing of her book They Are What You Feed Them. American Nordic combined skier and Olympic gold medalist Bill Demong also made an appearance at the booth as did Susan Francia two-time Olympic gold medalist five-time world champion WWW.VITAMINRETAILER.COM MAY 2015 Go to cvc for info about this advertiser EXPOWESTWRAPUP and coach and an American rower. Carlson also used Expo West as a platform to recognize Southtown Health Foods Chicago IL as its longest-running customer dating back a generation. Carlson President Carilyn Anderson presented a special plaque of recognition to Southtown Health Foods current owners Emil and Mary Ann Mahler for a half-century of continued support. It s been a pleasure to work together with another honorable family business that s been passed down to the next generation Emil said. and taking charge of their health. Their paying attention to preventing disease and being the best they can be. It s wellness instead of disease. It s our birthright. Now it s up to you to guide customers to expand their base and make their quality of life better. Kaylor also proposed the benefits of various mushroom extracts including Maitake mushrooms for immune and hormonal support as well as liver and nerve protection in addition to reishi mushrooms for overall healthy balance and finally lion s mane for healthy cognitive support. category said Arsha Boustani of Picasso Naturals in San Diego CA and for supplements liquid fish oil has been a popular demand as well not to mention more and more supplement companies are releasing chewable and gummy alternatives to their already established products. To check the pulse of retailing after news of the New York Attorney General s office cease-and-desist order against four major retailers on certain herbal supplements VR asked Shakir Karim from Philadelphia-based Wayne Avenue Health if the story affected their sales and if they are doing anything to compensate. It hasn t affected our store one bit Karim said. In fact our sales have increased Sessions Supplements and the Show Floor The supplement aisles at Expo West were brimming with new product launches mushroom extracts kids multivitamins and probiotics in various delivery forms anti-aging formulations and turmeric (curcumin) hot on everyone s list. Several vendor-sponsored sessions were also not to be missed. Here s a small sampling of what was happening on the show floor and in the session halls Twinlab hosted a youthful aging seminar presented by Gene Bruno director of category management and dean of academics at Huntington College of Health Sciences. Twinlab s focused on its Daily One Age-Defense Telomere Multi Age Defense multivitamin on the show floor. HerbPharm released its new children s line of herbal products including Immune Avenger Tummy TLC Ear Oil and Lemon Balm Clam Glycerite. Nordic Naturals announced its Omega Boost Family of products including Omega Boost Junior for essential omega-3 nutrition. Gaia Herbs showcased its new Turmeric Supreme Immune for immune support and healthy inflammatory function. Natural Vitality introduced its Whole Life Daily Multi caps a companion product to its Organic Life vitamins. EuroPharma introduced a host of new products including adding BCM95 OPC to its family of BCM-95 curcumin products and Clinical OPC grape seed extract. Hylands debuted Nerve Tonic a natural relief formula for stress. Coral LLC presented all new color coated packaging for its supplements. Companies are really pushing protein powders and shakes in the fitness The Winners Circle Hall of Legends Among the many awards handed out at this year s Expo West were the Hall of Legends inductions which welcomed 12 new members including SuperNutrition co-founder and director of education Michael Mooney who in 1973 along with his father Patrick Mooney created a not-for-profit vitamin research co-op that led to development of SuperNutrion anti-aging potency supplements. Michael founded SuperNutrition in 1977. Al Powers NOW Foods a pioneer in the natural products industry for over 40 years was also inducted into the Hall of Legends. Association Awards The American Botanical Council (ABC) announced that Loren D. Israelsen president of the United Natural Products Alliance (UNPA) was selected as the recipient of its 2014 Mark Blumenthal Herbal Community Builder Award. The award is granted annually to an individual in the herbal medicine community who has played a significant role in creating a sense of community among herbalists researchers members of the herb and natural products communities and related groups who work in the area of medicinal plants. Among his many noteworthy accomplishments since 1991 Israelsen has served as the president of the United Natural Products Alliance (formerly the Utah Natural Products Alliance) a global industry trade association dedicated to supporting companies and consumers. The American Herbal Products Association (AHPA) presented the Emil Mahler & Carilyn Anderson Reclaiming Our Health On Saturday morning Mushroom Wisdom held an authentic Japanese breakfast for early riser that also featured an enlightening presentation by Mark J. Kaylor PhD natural products industry consultant and founder of the Radiant Health Project titled Reclaim Your Health Discover Key Missing Elements in Modern & Alternative Medicine. Mark Kaylor Kaylor s presentation centered on what he called the three fundamental keys that are currently missing from both modern and alternative medicine today mainly 1) responsibility 2) prevention and 3) radiant health. He also stressed support for the whole person and the quest to reclaim the word natural. We need to maximize health and vitality Kaylor told the audience of retailers. Our health and healing is basically our responsibility and your customers are assuming responsibility 24 VITAMIN RETAILER (Continued on page 35) WWW.VITAMINRETAILER.COM MAY 2015 Go to sanhelios for info about this advertiser RESEARCHUPDATE Zinc Deficiency Linked to Immune System Response inc an important mineral in human health appears to affect how the immune system responds to stimulation especially inflammation new research from Oregon State University (OSU) shows. Zinc deficiency could play a role in chronic diseases such as cardiovascular disease cancer and diabetes that involve inflammation. Such diseases often show up in older adults who are more at risk for zinc deficiency. When you take away zinc the cells that control inflammation appear to activate and respond differently this causes the cells to promote more inflammation said Emily Ho a professor and director of the Moore Family Center for Whole Grain Foods Nutrition and Preventive Health in the OSU College of Public Health and Human Sciences and lead author of the study. Approximately 12 percent of people in the U.S. do not consume enough zinc in their diets. Of those 65 and older closer to 40 percent do not consume enough zinc Ho said. Older adults tend Z to eat fewer zinc-rich foods and their bodies do not appear to use or absorb zinc as well making them highly susceptible to zinc deficiency. It s a double-whammy for older individuals said Ho who also is a principal investigator with the Linus Pauling Institute. In the study researchers set out to better understand the relationship between zinc deficiency and inflammation. They conducted experiments that indicated zinc deficiency induced an increase in inflammatory response in cells. The researchers were able to show for the first time that reducing zinc caused improper immune cell activation and dysregulation of a cytokine IL-6 a protein that affects inflammation in the cell Ho said. Researchers also compared zinc levels in living mice young and old. The older mice had low zinc levels that correspond- ed with increased chronic inflammation and decreased IL-6 methylation which is an epigenetic mechanism that cells use to control gene expression. Decreased IL-6 methylation also was found in human immune cells from elderly people Ho said. Together the studies suggest a potential link between zinc deficiency and increased inflammation that can occur with age she said. We think zinc deficiency is probably a bigger problem than most people realize she said. Preventing that deficiency is important. Understanding why older adults do not take in zinc as well is an important area for future research Ho said. Additional research also is needed to better understand how zinc works in the body she said. For more information visit Vitamin D Helps Immune Cells Prevent Atherosclerosis Diabetes A ltered signaling through the vitamin D receptor on certain immune cells may play a role in causing the chronic inflammation that leads to cardiometabolic disease the combination of type 2 diabetes and heart disease that is the most common cause of illness and death in Western populations. The research appears in the journal Cell Reports. Because low vitamin D levels are associated with diabetes and heart disease we looked at the connections between vitamin D immune function and these disease states said Senior Author Carlos BernalMizrachi of the Washington University School of Medicine in St. Louis MO. The investigators found that when they engineered mice to lack expression of the vitamin D receptor in immune cells called monocytes and macrophages the animals accumulated atherosclerotic plaques in their blood vessels and developed insulin resistance meaning that their liver cells had a diminished ability to respond to insulin and regulate blood glucose levels. Inactivation of the macrophage vitamin D receptor promotes inflammation of the liver and of the artery walls. It also increases the ability of blood monocytes to adhere and migrate into the vessel wall where they deposit cholesterol and secrete inflammatory mediators to cause diabetes and heart disease explained Bernal-Mizrachi. This implies that vitamin D will reduce these properties in immune cells to decrease inflammation and reduce the risk of cardiometabolic disease. The research team found that bone marrow transplantation of cells that expressed the vitamin D receptor into mice lacking the vitamin D receptor in monocyte and macrophages improved the animals insulin sensitivity suppressed atherosclerosis and decreased the formation of fat-laden macrophages that accumulate along blood vessel walls. These results suggest that individuals may experience increased inflammation and serious health consequences when their immune cells are exposed to vitamin D deficiency or cannot process vitamin D. Indeed findings from previous studies suggest that individuals with vitamin D deficiency have an increased risk of developing diabetes and that adequate dietary vitamin D in patients with diabetes limits the formation of fat-laden macrophages and decreases atherosclerosis. Our findings provide further mechanistic foundation for multiple interventional trials including our own to evaluate the effects of vitamin D on cardiometabolic disease said Bernal-Mizrachi. In addition the identification of monocyte cholesterol transport as a mechanism for atherosclerosis in our animal model opens up a new area of research that could identify novel therapies for heart disease. For more information visit 26 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 Go to lifeextension for info about this advertiser RETAILFUNDAMENTALS The State of Social Media By Debby Swoboda Mayhew A s a retailer there is no way you could possibly be up on every social media avenue available ... platforms come and go some improve and meet your needs while others vanish into the past. Social media changes so often that it s hard to be an expert for very long. However what I have learned over the past years is that marketing is still marketing and the basics are just as important today as they were years ago to incorporate into whatever platform is used to share messages. In the past marketing was pushed out to the masses in hopes that a percentage would be persuaded to respond. What has changed is that people now search for information and follow the path that interests them. The retailer s goal has always been to be a trusted authority ... but now it s also about being found. The natural products industry has been an industry of storytellers looking for ways to share their knowledge. They now have powerful vehicles to do so and may just need a few tips to help them accomplish this. When I became aware of the power 28 VITAMIN RETAILER of social media marketing I read somewhere that people pay attention to online messages when they solve a problem save them money educate and or entertain them. I have shared and practiced that particular mantra many times ... I actually have posted it on a white board in my office and refer to it like a mission statement. Social media marketing goes beyond the software or platform--it s about creativity and a personalized strategy. What do you want to accomplish With that question in mind here are some suggestions to get your juices rolling. consistent) Create a Buzz Endorsements and reviews have always been a great way to share information about your business. However it s best to share your customers stories about how much they love your business rather than for you to say how much you re loved. Create a buzz that is worth sharing. TIP Do something amazing and have it shared A manager once selected someone standing in line during peak business hours and stated loud enough for others in line to hear Congratulations Today your purchases are on us. Thank you for your business Let s consider what might happen next. Do you think that anyone might share what just happened Do you think that they might try to figure out if this might happen again (A good practice if this strategy is used is to ask the intended recipient first if they would be comfortable with the attention.) Create a Foundation When using social media for marketing your business it s important to have a plan of what you want to accomplish and with what voice. Start by asking yourself the following questions What is your story (Build credibility) Who are you (Share your persona and passion--be real) Who is your audience (Your messages should support your niche and be aimed towards your target market) Are you worth following (Be (Continued on page 63) WWW.VITAMINRETAILER.COM MAY 2015 Go to essentialformulas for info about this advertiser ccording to research by the Centers for Disease Control and Prevention (CDC) approximately 6 percent of women in the U.S. are now infertile. Washington-based Fairhaven Health LLC s VP of Operations and Project Management Sarah Dohman weighed in on the fertility supplement market and believes the industry has witnessed considerable growth both domestically and internationally. We would contend that market demand for fertility supplements is significant and likely to expand further in coming years as the result of several contributing factors she noted. A key driver is the fact that couples are waiting longer to conceive their first child. It is fairly well-documented that couples are postponing having children longer than in previous generations for a variety of reasons including work financial situation and education. According to Duffy MacKay ND senior vice president scientific and regulatory affairs with CRN (Council for Responsible Nutrition) It s encourag30 VITAMIN RETAILER A ing to learn that women can do something so simple as adding the right micronutrients to their diets via a multivitamin to help protect their babies future health. We encourage women who are pregnant or considering to become pregnant talk with their doctors about how they can benefit from a prenatal multivitamin and other dietary supplements. In fact Jane L. Frederick MD FACOG international specialist in Reproductive Endocrinology and Infertility and medical director of HRC Fertility in California finds that it is important to begin taking prenatal vitamins once a woman decides to achieve pregnancy and many believe that vitamins should be taken at least three months before attempting to get pregnant. Unlike years ago when only synthetic multivitamins were available these days we are presented with whole food multivitamin alternatives which are a more natural bioavailable form of supplemental nutrients explained Hamilton Cabanilla national educator and territory manager with Enzymedica Inc. (Venice FL). Food based pre- and post-natals help as many of them have a less tendency to upset the stomach explained Bob Dagger retailer and owner of High Vibe in New York City. Impacting Fertility According to The American Society for Reproductive Medicine (ASRM) fertility changes with age in fact both men and women become fertile in their teens following puberty. Young women begin their reproductive years by the onset of ovulation and menstruation. Then as women grow older approximately five to ten years prior to menopause their chances of fertility decrease. Pregnancy results if the egg becomes fertilized and implants in the lining of the uterus (endometrium). If pregnancy does not occur the endometrium is shed as the menstrual flow and the cycle begins again ASRM explained. However fertility naturally declines as women age generally WWW.VITAMINRETAILER.COM MAY 2014 2015 Celebrating 20 Years of Excellence 1994-2014 Go to amazingherbs for info about this advertiser around their late 20s or early 30s and then it falls more rapidly after the age of 35. Women who decide to delay pregnancy until their 35 should obtain information on appropriate testing and treatment while remaining realistic about the chances for success with infertility therapy ASRM continued. Therefore women should educate themselves about all of the options and become aware of their individual needs and goals. According to ASRM a woman is diagnosed as infertile if she has not become pregnant after one year of unprotected sex. Dohman contributes a number of factors into why women are finding it harder to become pregnant stress is a leading factor followed by smoking drinking caffeine and various prescription and over-the- counter medications as well as environmental factors including air water and food. Fredrick also believes there are many factors that contribute to the lack of fertility that are not only directed toward women but toward men as well. For females nearly 40 percent are diagnosed with anovulation the absence of an egg during their menstrual cycle she explained. Other women have a low ovarian reserve fallopian tube damage or uterine fibroids. Some women have endometriosis polycystic ovarian syndrome and in some cases a complete undiagnosed medical issue. Researchers found that almost half of all cases are directly caused by male factors such as a low sperm count making it harder to impregnate his partner. In fact 40 percent of men are either the cause or the main factor in infertility the ASRM noted. before exploring the effective natural options that are available Dohman said. Fairhaven Health has been involved in the fertility supplement market since 2005 watching the industry grow. The company s top selling products are its FertilAid line available for men and women. They are the No. 1 nutraceutical targeting reproductive wellness Dohman said. FertilAid for Women uses vitex agnus castus as its Fairhaven Launches Breastfeeding App After delivery if all goes well the mother will be ready to jump right into breastfeeding. But in many cases the natural process between mother and baby is not that easy and can be jeopardized by confusion stress and pain. Fairhaven Health LLC takes fertility preconception and pregnancy products to the next generation through a new partnership with latchMD s supportive breastfeeding application latchME--a reliable and easy-tounderstand resource for first-time mothers who are breastfeeding. The app offers a variety of features while connecting mothers to experts peer groups stores maps of nearby breastfeeding spots and more. latchME the new Yelp for breastfeeding was created by professionals and experts in breastfeeding to make the transition an easy one thanks to the app s interactive help information and support. latchME is proud to partner with Fairhaven Health. Like latchME Fairhaven understands and truly cares about the emotional and physical health of growing families said one latchME representative. Both companies help women find quality resources ... [And] both support the World Health Organization s International Code of Marketing of Breast-Milk Substitutes. Together we literally put breastfeeding support on the map for so many mothers who desperately need it. For more information visit or To download the app visit latchMEapp.html. WWW.VITAMINRETAILER.COM MAY 2015 Lil Helpers Too often couples are prematurely pushed down the path of expensive infertility treatments and medications 32 VITAMIN RETAILER Go to ajinomoto for info about this advertiser main ingredient since it has been shown to stimulate the hormones involved in ovulation and helps restore hormonal balance she continued and FertilAid for Men s main ingredient is Lcarnitine which plays a vital role in the process of sperm development. Fairhaven Health has added three more products OvaBoost CountBoost MotilityBoost. OvaBoost helps egg quality and contains myo-inositol folic acid and melatonin. CountBoost and MotilityBoost are companion products as the company calls them to FertilAid for Men. Folic acid is a popular supplement taken for fertility. This well-researched nutrient plays a critical role in preventing birth defects of the brain and spinal cord call neural tube defects (NTDS). In fact there have been numerous studies that show NTDs can potentially be prevented with folic acid supplementation which is why the March of Dimes and other health organizations recommend it she said. The recommended daily value of folic acid is anywhere from 600-800 mcg and can be digested through cooked lentils cooked spinach cooked broccoli and orange juice. However it can also be reached by taking daily vitamins such as Rainbow Light s Prenatal One Multivitamin or Precious Gems Gummy. New research published in the Journal of Ethnopharmacology found that ashwagandha an herbal alternative used in ayurvedic medicine also known as the Indian ginseng restores the appropriate functions in men involved in fertility. The study used 230 male participants. One hundred eighty infertile men were given 5 g of ashwagandha root powder every day for a three-month period and 13 different compounds found in semen were closely watched before and after the study. Researchers also measured the sperm concentration motility hormones and other factors. The results of the study showed that ashwagandha in men recovered the quality of semen of posttreated compared to pre-treated infertile men. Therefore not only does the herbal medicine reboot enzymatic activity of metabolic pathways and energy metabolism but it also invigorates the harmonic balance of seminal plasma metabolites and reproductive hormones in infertile men. DHA also used during pregnancy and has been known to help with the development of a baby s brain and the ability to learn judge and concentrate Clow explained. In a study published in Child Development researchers measured blood levels of DHA in infants and mothers at delivery she reported. Infant cognitive development was assessed at 4 6 8 12 and 18 months of age and the infants whose mothers had high DHA at birth showed greater cognitive development during the study. The conclusion was consistent with previous studies over the last five years which provides us with evidence linking DHA and cognitive development in infancy she continued. With evidence shinning light on DHA for fertility Rainbow Light offers Prenatal Multivitamin made with organic fruits and vegetables and Prenatal Precious Gems with DHA. In addition Rainbow Light recently released its Embrace Prenatal 35 for women who want to conceive over the age of 35. According to the U.S. Census Bureau 11 percent of babies born in the U.S. each year are born to women over the age of 35 with 64 percent being first-time mothers. The company s first age-specific prenatal addresses specific symptoms and needs for moms age 35 and up by providing clinically researched nutrient potencies to nourish and protect throughout pregnancy and nursing. Embrace addressed the complex The Couple s Toolbox Fruitful Way Ltd. has crossed the digital spectrum and released a natural fertility toolkit for couples trying to conceive. The his and hers duo includes science-supported dietary supplements for him and her along with an advanced fertility application to make sure both partners take their supplements on a regular basis and will continue to follow the fertility program. One of the most important features of Fruitful App is that the father-to-be is involved in every aspect of the fertility process and as a result he becomes a full partner of this route said Udi Alroy CEO and founder of Fruitful Way. This bonding is essential for fertility success in two ways It helps the mother-to-be feel she has a true partner for this mission and it places vital emphasis on the male s key role in their getting pregnant. In addition Sharon Shmueli MD Fruitful Family Practitioner said Ignoring the man s role can lower a couple s chances of getting pregnant. Fruitful can help couples get pregnant by providing a complete program that addresses both the man and the woman and targets their specific habits lifestyle and risk factors. WWW.VITAMINRETAILER.COM MAY 2015 Go to michelles for info about this advertiser 34 VITAMIN RETAILER needs and conditions associated with mature pregnancies she said. Digestive enzymes are also becoming a staple in an expectant mothers natural supplement list explained Cabanilla. During pregnancy digestive enzymes are important to help assist the body in digesting and extracting the nutrients from the good dietary choices they are making which will allow the nutrients vitamins and minerals in food easy to reach their destination and serve the purpose for which they were ingested she continued. Digest Pregnancy by Enzymedica Inc. is a pure and gentle blend of vegetarian digestive enzymes along with organic ginger to help women cope with digestive discomforts such as nausea gas and bloating common to pregnancy. After Baby s Arrival According to Marci Clow MS RDN nutritionist at Rainbow Light (Santa Cruz CA) it s a smart idea to take prenatal vitamins all the way through pregnancy and while breastfeeding. This will help to replenish your body and ensure your baby gets the essential nutrients necessary for healthy development she said. We now see prenatal multivitamins in a variety of forms to meet the needs of a broad range of consumers including oneper-day and multi-tablet formulas capsules and gummies which are especially helpful for women who are experiencing nausea and have trouble taking tablets. And although a multivitamin is an essential during fertility there are a variety of other vitamins and minerals that play a substantial part in fertility for both men and women. According to the CRN dietary supplement manufacturers should include a daily serving of at least 150 mcg of iodine in all multivitamin mineral supplements intended for pregnant and lactating women in the U.S. CRN developed these guidelines in response to recommendations from the American Academy of Pediatrics the Endocrine Society and the American Thyroid Association. Scientific evidence shows that similar to folic acid adequate iodine is critical early in pregnancy when the fetal brain is growing rapidly said MacKay. Currently many U.S. women of childbearing age get insufficient dietary iodine putting their children at risk for decreased cognitive functions. The Council provides women the scientifically backed amount of iodine that is needed. VR These statements have not been approved by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. Extra Extra Visit to read about a traditional Chinese medicine approach to fertility i For More Information Fairhaven Health LLC (360) 671-0859 Rainbow Light (866) 972-6879 Enzymedica Inc. (941) 441-3783 EXPOWESTWRAPUP (Continued from page 24) 2015 AHPA Awards to individuals and companies that have made substantive positive contributions to the herbal products industry. This year s AHPA Award winners are Dick Griffin former owner of Grifcon Enterprises was awarded the AHPA Herbal Hero Award in recognition of the tremendous benefits that his insurance programs provided to the dietary supplement industry. James Prochnow a shareholder at Greenberg Traurig presented the award highlighting that Griffin is one of the pioneers of developing product liability insurance for the dietary supplement industry. Prochnow also noted that Griffin has been a generous and active supporter of AHPA. Mountain Rose Herbs was presented the AHPA Herbal Industry Leader Award for taking steps above and beyond normal business practices to advance the herbal products industry. Beth Lambert CEO of Herbalist & Alchemist presented the award to MAY 2015 WWW.VITAMINRETAILER.COM Mountain Rose Herbs co-president Shawn Donnille and other employees of the company. Tieraona Low Dog MD was awarded the AHPA Herbal Insight Award in recognition of her efforts to significantly increase and further knowledge and understanding of botanicals and their uses. Dr. Low Dog is an internationally recognized expert in the fields of dietary supplements herbal medicine women s health and natural medicine. Engredea Too Co-located with Natural Products Expo West was Engredea and the NEXT Innovation Summit to deliver a full spectrum of opportunities to enter grow and succeed in the global health and nutrition marketplace according to show organizers. Clean label curcumin plant protein and vitamin K were among the hottest topics of this year s Engredea as were bone and vision health. OmniActive Health Technologies celebrated the second anniversary of its education campaign--Lutein for Every Age--dur- ing the trade show. Attendees were surprised with a sponsorship that included three performances by a flash choral mob ranging from children to seniors singing about the importance of the macular carotenoids lutein RRzeaxanthin and RS-zeaxanthin. OmniActive also introduced Gingever High Potency Ginger for the first time. Non-GMO and allergenfree Gingever is a high-potency supercritical fluid extract with 30 percent bioactives made from an FDAacknowledged GRAS (generally recognized as safe) source. Sabinsa Corporation unveiled a new form of curcumin Curcumin C3 Reduct which seeks to solve the problem of staining and C3 Complex the most studied curcumin in the world. Hold Those Dates Natural Product Expo East 2015 will return to the Baltimore Convention Center September 16-19 2015 in Baltimore MD. Natural Products Expo West will return to Anaheim CA March 9-13 2016. VITAMIN RETAILER 35 Essential Minerals While vitamins continue to grab headlines the need for minerals is also vital to good health. By Daniel Breeman oth vitamins and minerals each have a unique role in satisfying nutritional needs. But while both are critical in helping to maintain overall health vitamins have long been the star attraction among consumers in part due to their shelf presence in stores and marketing push in the media. Minerals (both macrominerals and microminerals) such as calcium magnesium iron copper and iodine just to name a few have long taken a backseat to their more popular counterpart but have critical roles to play in the body including help in bone and tooth formation regulation of blood coagulation and proper heart function as well as energy production and muscle contraction. In short minerals are every bit as important as vitamins for proper nutrition and in helping to maintain and support an array of vital bodily functions. Minerals are the unsung heroes of nutrition said Gene Bruno MS MHS VMS formulation Twinlab (Hauppauge NY). The importance of minerals has often been overshadowed by the spotlight that vitamins have held in general but the need for minerals is vital. In fact they (minerals) were even recognized as essential to human nutrition long before vitamins were discovered. Minerals are every bit as critical as vitamins to our body s function being B involved in over 1 000 biochemical reactions added Jacob Teitelbaum MD director of the Practitioners Alliance Network. They are critical for pretty much every function that we have including function of the brain energy production heart and immune function and pretty much anything else you can think of. Bruno also pointed out that the body can tolerate a deficiency to vitamins for a longer period of time than it can a deficiency of minerals. A slight change in the blood concentration of important minerals may rapidly endanger life he said. Vitamins Minerals & Education Many consumers looking for minerals or mineral supplements are familiar with the more popular ones such as calcium and magnesium but are often in need of guidance when it comes to getting exactly what they need to ensure the proper daily mineral intake. There is a lot of education that needs to be done in the area of minerals said Angelique Saffle co-owner of Nature s Marketplace Nutrition North Bend WA and president and founder of Bodyceuticals Calendula Skincare Carnation WA. Most consumers know calcium magnesium and iron ... but beyond that they don t really know what minerals are and why they are important to the body. As an industry we need more consumer education here. While eating a healthy diet remains the best way to to get both the vitamins and minerals needed on a daily basis supplementation has now been pushed into the spotlight as well as mineral depletion has become an industry issue that needs to be addressed. The industrialization of our food supply has played a significant role in the depletion of minerals in our diets said Stacey Littlefield product formulator for Redd Remedies (Bradley IL) maker of BONEhealth Original and BONEhealth Advanced supplements. From the poor soil quality of chemically managed farms to the over-processing of grains minerals have seen stripped from our foods from the ground up. Adding fuel to the fire is the lack of fresh vegetables fruits and whole grains in the standard American diet (SAD). These issues can be corrected by making some simple choices such as choosing organic produce whenever possible incorporating fresh fruits WWW.VITAMINRETAILER.COM MAY 2015 36 VITAMIN RETAILER Go to drwillards for info about this advertiser Essential Minerals vegetables and whole grains into the diet and supplementing the diet with multivitamin mineral or mineral supplements. According to Teitelbaum an unprocessed diet has approximately 600 mg a day of magnesium while the average SAD supplies about 275 mg daily and can contribute to a large increased risk of heart attack deaths. We have lost over half of the minerals in our diet because of food processing with further losses coming from soil depletion from over-farming Teitelbaum said. The farmers only give the plants what they need to grow not what humans eating the plant need. Farming practices that result in mineral depletion have prompted some industry manufacturers like Natural Vitality (Austin TX) makers of PlantSourced Minerals naturally chelated ultra mineral supplements and liquid supplements to support two non-profit organizations through its Calm Planet Project in order to address this pressing issue. This will address how depletion can be corrected at the soil level so our plants contain higher levels of minerals said Ken Whitman president of Natural Vitality. Through the Bionutrient Food Association thousands of growers have been trained in cost-effective techniques of growing nutrient-rich produce. Vitamins vs. Minerals Vitamins are organic compounds that humans obtain from plants and animals. Minerals cannot be made in the body and must be obtained from an individual s diet. They are inorganic and obtained from soil and water. Both vitamins and minerals are considered essential nutrients and work together to perform numerous key roles and functions in the body. Approximately 4 percent of the body s mass consists of minerals which are divided into macrominerals or major minerals and microminerals 38 VITAMIN RETAILER sometimes referred to as trace minerals. The six major minerals required in excess of 250 mg per day include calcium magnesium potassium phosphorous sodium and chloride. Trace minerals are iron zinc selenium iodine fluorine and chromium. Calcium and magnesium are necessary for the formation of bones and teeth blood clotting and for normal muscle and nerve activity while magnesium also plays a role in the formation of bones and teeth and is necessary for normal functioning of muscle and nervous tissue. Iron is a part of the protein hemoglobin which carries oxygen from place to place in the body. Iodine copper potassium manganese selenium and chromium also have major functions and all are important to complete health. While getting the proper intake of all minerals through proper diet and supplementation special attention should be paid to magnesium according to many experts along with the often-lacking trace minerals. All minerals are important for good health said Bruno. However a special call-out should be given to magnesium due to insufficient intake. Although overt magnesium deficiency is not common the U.S. Department of Agriculture (USDA) Agricultural Research Service has reported that 57 percent of the U.S. population does not meet the recommended dietary allowance for levels of magnesium. Natural Vitality s Whitman also pointed to the importance of magnesium in the diet its desired intake balance with calcium and other minerals and the role supplementation plays in bringing it all together. Some of the health benefits of magnesium include support for migraines insomnia and depression regulation of high blood pressure support for cardiovascular health and even studies that have suggested it can improve bone mineral density when supplemented with calcium. Supplementation affords the opportunity of remedying mineral deficiencies Whitman said. Unfortunately there is no broad agreement about the right balance of minerals. A prime example is calcium to magnesium ratio. Most manufacturers and many health care professionals recommend a 2-to-1 (calcium-to-magnesium) ratio. Probably the most effective thing retailers can do to help customers is to inform them of the need to balance cal- cium intake with magnesium. Many women have been told to take calcium supplements and may already have a high calcium diet from dairy products. Too much calcium can be detrimental to health and potentially lead to serious problems. Asking people who are buying supplements if they are also taking sufficient magnesium would be a compassionate service. We consider magnesium to be one of the crucial minerals for human health added Redd Remedies Littlefield. People simply don t get enough magnesium in their diets. Trace minerals are equally as important as it is these minerals that are the critical metallic core of necessary enzymes. In order of priority the most important minerals are magnesium potassium zinc iodine and chromium offered Teitelbaum. Iron should only be supplemented if blood testing shows the need. Trace minerals are also critical. Supplements & the Customer According to USDA data only 10 percent of Americans are following dietary guidelines meaning that most are not receiving adequate amounts of micronutrients including minerals. This again is where supplementation can again be front and center. Without supplementation it is almost impossible to get adequate let alone optimal amounts of all the minerals needed Teitelbaum said. Taking them all as individual tablets is not an attractive solution as there an be handfuls of pills and therefore would be getting amounts that are imbalanced. There is a nutrition primer that gives the optimal amounts for supplementing each mineral that should be used he added. Twinlab s Bruno noted that according to the goals of nutrient intake established by the USDA when comparing the nutritional goals for Americans to the nutrient content of foods consumed in a 2 000 calorie-per-day diet there will be insufficient amounts of magnesium and potassium. So even if you follow dietary guidelines you won t be reaching 100 percent of your nutrient intake goals he said. Supplementation can play a key role in making sure that individuals are getting a balanced intake of minerals in the diet added Littlefield. Most naturalchannel multivitamin-mineral supplements have all the key macro- and micro-minerals essential to health. If an individual wants more targeted mineral supplementation he or she can choose WWW.VITAMINRETAILER.COM MAY 2015 Go to scandinavian for info about this advertiser Essential Minerals calcium and magnesium supplements for bone health or magnesium and potassium supplements for muscle health. Of course with supplementation comes customer inquiry and often customer confusion regarding just which mineral supplements are right to take. There is also the question of which delivery method (i.e capsules liquids chewables etc.) may be the best option for that particular individual. Coral LCC (Carson City NV) for example has launched Coral Chewables offering the benefits of coral minerals in a chewable Bavarian Cream-flavored tablet with 500 mg of calcium and 73 other minerals from coral. Recommending the right delivery method is where the natural product retailer must play the role of educator. It s vital that our store team members are educated about minerals said Saffle who noted that her store dedicates a good amount of shelf space to minerals with the most popular being calcium and magnesium. Minerals play such a critical role in optimal health of our body. Minerals themselves and the role they play in good health are generally easy to explain and understand. The more confusing and difficult thing to explain is the many different forms of minerals and how to differentiate their quality absorption and efficacy. This is where retailers play a crucial role working on the front lines with customers every day. With so much to learn and keeping busy in our stores this is where we appreciate our manufacturers who can provide cutting-edge education in this area. One of the manufacturers Saffle points to as a leader in minerals education is Vitalah (Watsonville CA) maker of Oxylent and Sport Oxylent a 3-in-1 supplement drink that contains a blend of vitamins C D B6 and B12 along with a host of Albion minerals. As far as delivery methods go that is usually left to the customer to decide depending on individual preferences or sometimes issues with swallowing pills or simply not enjoying a supple40 VITAMIN RETAILER ment-based drink. Is there really a difference that consumers need to be aware of The key more experts agree is absorption. We believe in liquid as the best delivery method said Natural Vitality s Whitman. All pills and capsules need to become liquefied in order to absorb. If you begin with liquid or water-soluble powder your are beginning with a bioavailable solution. Absorption is key added Saffle. We suggest our customers learn about chelated minerals and why they offer such high bioavailability. The most important thing to know and to get across is how difficult it is for our bodies to absorb minerals in the forms they are found in our food and in typical supplements. Even in optimal conditions minerals are only moderately well absorbed. The process of chelation transforms minerals from the inorganic form that is difficult to absorb into the organic form that is much more readily absorbed and metabolized by our bodies. Bluebonnet Nutrition (Sugar Land TX) recently introduced a line of Albion minerals Chelated Magnesium Bisglycinate capsules that provide 200 mg of elemental magnesium per serving in a more bioavailable bisglycinate form to support heart health and other key functions. The best way to absorb minerals is to take an amino acid chelate forms of those nutrients said Trisha Sugarek MacDonald BS MS director of research and development and national educator at Bluebonnet. The reason for this is simply because when a mineral is taken as a non-chelated form it is vulnerable to being rendered useless by food components such as oxalates phytates fatty acids and more. When minerals are chelated to aminos they are strong enough to survive the pH of the gut but weak enough to be absorbed by the small intestine through active transport making them more bioavailable and bioactive. And once absorbed they are essentially whole food nutrition since you not only have the benefit of the minerals but also the amino acids. So it s a win-win. According to Bruno the best way to absorb the minerals needed on a daily basis is to take a good mineral supplement from a reputable supplement company. As for delivery methods he indicated that popular delivery methods include capsules and tablets although some liquid supplements are available and alternative delivery meth- ods such as gummies are popping up although they are not necessarily better for absorption than capsules. Too Much While heeding the warning against not getting enough minerals is paramount to overall health and well-being there is also some concern that getting too much of a good thing can also be a danger. You can always get too much of a good thing said Bluebonnet s Sugarek MacDonald. The dangers of excess mineral intake are numerous and vary depending on the mineral that is over consumed. Minerals function throughout the cells and tissues of the human body to maintain health but taking in excessive levels of these nutrients can be detrimental to the body s wellbeing. That s why getting a good balanced form is very important according to Teitelbaum in order to avoid potential health risks. Taking plain calcium tables can be associated with a 31 percent risk of heart attack. This is why they need to be combined with vitamin D magnesium and vitamin K. It s possible to get too many minerals on a daily basis added Littlefield. It s easier to do this with the microminerals. Chromium for example has limits as to the amounts beneficial for health. Once we go over that threshold it can begin to cause problems in the body. Also large amounts of iron should be taken away from calcium because they compete with one another for absorption. While proper intake must be adhered to Bruno suggested that this should not scare off consumers from getting the minerals they need. It is certainly possible to get too much of any mineral but if people stick reasonably close to the Daily Value levels there is not likely to be a problem. VR Extra Extra Visit to learn about a study that links zinc deficiency to immune system response. i For More Information Bluebonnet Nutrition (800) 580-8866 Coral LCC (800) 678-9884 Natural Vitality (800) 446-7462 Redd Remedies (888) 453-5058 Twinlab (800) 645-5626 Vitalah (877) 699-5368 WWW.VITAMINRETAILER.COM MAY 2015 2015 ScienceofSupplements SUMMERISSUE 2014 his special section of Vitamin Retailer (VR) comes in response to the industry s desire for more information--retailers wanting more information about the products they sell and manufacturers wanting to offer the science that backs the effectiveness of their products. We have featured a similar section annually in VR s sister publication Nutrition Industry Executive since 2002 where it is designed to help manufacturers gain a better understanding of the ingredients and services available that can make their products stand out. VR is once again responding to retailers increased demand for science and research by offering this section twice-- first here in our May issue with our summer installment and then again in our November issue--providing companies with two opportunities to describe in some detail to our readers the insight and research that goes into their products. Companies advertising in this issue of VR have provided one-page reference articles to a) help our readers decide if they want to carry a product in their stores or b) refer a customer to when they re asking about the research behind a particular product. Manufacturers have responded to this opportunity with background information about the health concerns their products are intended to address histories of the nutrients behind their products and details of research carried out on their products. We ve also provided company addresses phone numbers and website addresses to make obtaining additional information easier. T Following is an index of companies participating in the 2015 VR Science of Supplements Summer Issue section Amazing Herbs..............................................................42 Bluebonnet Nutrition ....................................................43 Dr. WIllard s Water CAW Industries Inc. ......................44 Essential Formulas Inc. ................................................45 Life Extension................................................................46 Nordic Naturals ............................................................47 North American Herb & Spice ......................................48 NOW Foods ..................................................................49 Pharmachem Laboratories Inc. ....................................50 Rainbow Light Nutritional Systems ..............................51 Redd Remedies ............................................................52 Scandinavian Formulas Inc. ........................................53 Superior Source Continental Vitamin Co. Inc. ............54 Wakunaga of America Co. Ltd. ..................................55 Xlear Inc. ......................................................................56 MAY 2015 WWW.VITAMINRETAILER.COM VITAMIN RETAILER 41 2015 ScienceofSupplements SUMMERISSUE Amazing Herbs 2709 Faith Industrial Dr. Ste. 500 Buford GA 30518 Phone (770) 982-4780 Fax (770) 982-0273 Email info Website Black Cumin Seed A Multi-faceted Ingredient for Immune and Inflammatory Response By Waseem Goreja President and CEO of Amazing Herbs any diseases are associated with inflammation allergies asthma cardiovascular disease diabetes rheumatoid arthritis and colitis. Amazingly up to 25 percent of all cancer is caused by chronic inflammation due to infection or chronic disease.1 An imbalance of chronic inflammation and poor immune response underlies essentially all diseases of aging and early death.2-5 Consumers are turning to natural ingredients that attempt to target inflammatory response. Natural ingredients such as black cumin seed (Nigella sativa) offer a multi-faceted approach to inflammation. For centuries people around the world have used black cumin seed also known as black seed for a vast variety of health concerns as an analgesic antioxidant digestive aid to improve kidney and liver function and to alleviate the symptoms of arthritis and asthma.6 Ancient people traditionally called these seeds panacea. 7 8 Present day research shows more definitively and rigorously just how and why this plant is such a panacea. There is now abundant scientific evidence that black cumin seed oil may be a powerful catalyst for inflammatory and immune system response.7-11 One of the most researched active components of black cumin seed oil is thymoquinone (TQ). As early as 1956 researchers isolated this unique component and since then more than 500 studies helped shed light on black cumin seed and TQ mechanism of action in a broad range of ailments and diseases.28 Some of the research surrounding TQ involves the chronic inflammatory conditions of allergies and asthma. Researchers have shown a drastic reduction in allergic rhinitis symptoms after treating patients with black cumin seed12 as well as relaxation of the tra- M chea and bronchi during an asthmatic attack after treatment with TQ.13 14 In animal studies involving another inflammatory disease colitis treatment with TQ completely prevented the onset of the experimentally induced disease.15 It also has a protective effect on the gastric system against ingested toxins.16 17 In a study of 40 patients with rheumatoid arthritis treated with black cumin seed oil 42 percent of the patients had fewer swollen joints and less morning stiffness.18 In osteoarthritis studies TQ effectively reduced levels of an enzyme called matrix metalloproteinase that breaks down bone and joint tissue.19 Atherosclerosis is a chronic inflammatory response that is particularly dangerous as it leads to other types of cardiovascular disease. Black cumin seed oil reduced levels of oxidized low-density lipoprotein cholesterol (LDL) counteracting the harmful effect it has in thickening arteries characteristic of atherosclerosis.20 21 Animals treated with black cumin seed oil had lower levels of bad cholesterol or LDL and higher levels of good cholesterol high-density lipoprotein cholesterol.20 21 Also black cumin seed oil was shown to protect the body against ischemia-reperfusion injury which plays a part in brain trauma and other damage associated with stroke and heart attack.22 Promising research suggests that TQ may also play a role in when dealing with a variety of cancer types-- breast lung colorectal pancreatic prostate leukemia osteosarcoma and glioblastoma.23-25 Interestingly it does this through different mechanisms of action--directly killing cancer cells inhibiting the spread of cancer cells cutting off the nutrient supply to the tumors through inhibiting angiogenesis and enhancing chemotherapeutic effects.23-25 In head-to-head studies with tricho- statin A an HDAC (histone deacetylase) inhibitor which is used to fight inflammation-associated cancers TQ yielded far better results.25 26 When animals with pancreatic cancer were treated with TQ 67 percent of the tumors were significantly shrunken and the levels of proinflammatory cytokines in the tumors were significantly reduced.25 Researchers have also shown improvements in memory cognition and attention in healthy men taking black cumin seed powder once a day for nine weeks.27 These effects are likely due to black cumin seeds antioxidant and anti-inflammatory effects. This treasure trove of healing black cumin seed known centuries ago for its medicinal properties has now caught the attention of consumers and modern science. The scientific evidence of its powerful anti-inflammatory effects is extensive showing benefits in treatment of a wide variety of cancers diseases and ailments and even enhancing memory. The bountiful effects of black cumin seed oil and TQ can only be realized when using a high quality therapeutic grade ingredient like Amazing Herbs 5X-TQ Premium Black Seed oil which contain 5X the amount of naturally occurring TQ of any other product available on the market. Amazing Herbs pioneered Black Cumin Seed nutritional supplements more than 20 years ago and is the leading producer of this remarkable dietary ingredient. For a full list of references visit WWW.VITAMINRETAILER.COM MAY 2015 42 VITAMIN RETAILER 2015 ScienceofSupplements SUMMERISSUE Bluebonnet Nutrition 12915 Dairy Ashford Sugar Land TX 77478 Phone (281) 240-3332 Fax (281) 240-3535 Email bobjr Website Nutritional Benefits of Plant-based Protein Suited for Vegetarians Vegans Q What are the myths surrounding vegetarian vegan diets and protein intakes A The quality of protein you consume can significantly affect your health. With an increasing number of vegans and vegetarians the quality of protein from plant sources is a prevalent topic. People have questions when pondering the subject of a vegetarian diet especially in regards to consuming adequate protein. Questions and comments like Can you get enough protein on a vegetarian diet or Vegetarian protein is not as complete as animal protein. Undoubtedly these are obvious myths that plague consumers vegetarians and healthcare professionals alike. The following chart debunks the myths surrounding vegetarian vegan diets and protein intake for Americans 2010 10 to 35 percent of caloric energy should come from good high-quality protein. What is known in the scientific literature is that a vegetarian diet can easily meet human dietary protein requirements as long as the basic energy needs (in terms of calories) are met and a variety of foods (e.g. legumes soy products grains nuts and seeds) are consumed throughout the day. In fact on a global basis plants provide approximately 65 percent of the world s supply of edible protein. Bluebonnet s Super Earth Organic VeggieProtein Powder offers those wanting to increase their protein intake in a complete way without consuming soy dairy or animal proteins since it provides complementary plant sources with naturally occurring essential fatty acids and amino acids. A Plant-based foods like legumes most whole grains fruits vegetables nuts and seeds all provide amino acids but are not complete proteins by themselves. However the body does form an amino acid pool from these foods eaten throughout the day which can be used to provide all of the necessary amino acids required in the diet. There are different combinations of plant foods that can be selected so you can choose which foods you prefer. For example two of the most abundant plant sources of protein available for supplementation other than soy are brown rice (grain) and peas (legume). As a complement to rice protein pea proteins provide all the necessary amino acids that are lacking in rice to make a complete protein source which is why many vegetarian protein formulas like Bluebonnet s Super Earth Veggie Protein provide the two in combination. Q Can a vegetarian vegan diet provide enough protein for optimal health A According to the Dietary Guidelines Q Why combine vegetarian sources of protein Myths 1. Plant proteins are incomplete (i.e. lack specific amino acids) 2. Plant proteins are not as good as animal proteins 3. Proteins from different plant foods must be consumed together in the same meal to achieve high nutritional value 4. Plant proteins are not well digested Reality 1. Usual dietary combinations of plant proteins are complete specific plant proteins may be low in specific amino acids 2. Quality depends on the source and dietary mixture of plant proteins can be equivalent to high-quality animal protein 3. Proteins do not need to be consumed at the same time the balance over the day is of greater importance 4. Digestibility can vary according to plant source and preparation digestibility can be high Q What are the health benefits of vegetarian-sourced protein compared to animal-based protein A In recent years interest in animal-free foods has increased tremendously due to factors such as the use of growth hormones and antibiotics in animal feed as well as the rise of nutritionally dependent illnesses like type II diabetes cardiovascular and digestive diseases along with cultural religious orientations of denying animal intakes of any kind. Vegetable protein like Bluebonnet s Super Earth Organic VeggieProtein Powder that is soy- dairy- and glutenfree has become a cornerstone for healthy eating. This is because according to research when supplemented vegetable protein was found to help improve immune function support a healthy weight and lean body mass and aid in maintaining healthy blood pressure cholesterol and glucose levels that are already within the normal range. For a full list of references visit VITAMIN RETAILER 43 5. Plant proteins alone are not sufficient to achieve adequate protein intake 5. The intake balance of essential amino acids and nitrogen are crucial and can be adequately met from plant- and animalsourced 6. Plant proteins are imbalanced and this limits their nutritional value 6. There is no evidence that amino acid imbalances per se are important possible imbalances can be created by inappropriate amino acid supplementation but this is not a practical problem Chart adapted from Young VR Pellett PL. Plant proteins in relation to human protein and amino acid nutrition. Am J Clin Nutr 1994 59 (suppl) 1203S-1212S. MAY 2015 WWW.VITAMINRETAILER.COM 2015 ScienceofSupplements SUMMERISSUE Dr. Willard s Water CAW Industries Inc. P.O. Box 4040 Rapid City SD 57709 Phone (888) 379-4552 E-mail willardwater Website Recent Clinical Studies Shed New Light on How Drinking Willard Water Enhances Bioavailability of Nutrients Antioxidants and Vitamins M ore than 40 years ago scientist John Willard PhD made an amazing discovery. At the time this chemistry professor was in the process of conducting research on a highly concentrated trace mineral water when he serendipitously made a discovery. He was working on his trace mineral water when he had an inspiration to combine his trace mineral water with another product he d been developing. With that small stroke of inspired genius he had invented Willard Water. Willard first named his amazing discovery Catalyst Altered Water because the newly created product causes the formation of a catalyst that alters the structure of water making water behave in a manner that had not been reported in the literature as stated by Willard. This amazing water also includes fossilized organics that consist of activated carbon amino acids trace minerals and refined lignite (lignite is the fossil remains of plants that grew 50 million years ago). As a scientist Willard was intensely interested in the reasons behind the positive qualities of his newly invented Catalyst Altered Willard Water. He spent the rest of his life working with scientists at universities such as Purdue University the University of British Columbia and the South Dakota School of Mines and Technology among several others. Together these scientists worked to conduct in-depth research on the science and overall efficacy behind Willard Water. CAW Industries the manufacturer of all Dr. Willard products has sponsored a series of studies over the last few years in an effort to build on what has been learned in the previous four decades regarding the many benefits of drinking Willard Water and gain a better understanding of exactly how Willard Water is positively affecting cellular absorption of nutrients. These studies have confirmed what s been known for 40 years--Willard Water enhances cellular absorption of nutrients vitamins and antioxidants. The first study conducted in October of 2011 entitled An Examination of Willard Water s Impact on Vitamin Efficacy confirmed that drinking Willard Water significantly improved the efficacy of multiple vitamin supplements including critical nutrients such as vitamins D B12 and B6. The study s objective was to quantify that drinking Willard Water significantly improves the human body s ability to absorb vitamins. The three-month study sought to measure the impact of both Willard Water Dark and Willard Water CLEAR on the absorption rates of various vitamins in human subjects. The study also sought to determine whether there is a measurable difference between Willard Water s effects on fat-soluble vs. water-soluble vitamins. According to the study s author Dr. Hildegarde Staninger Willard Water significantly improved the efficacy of multiple vitamin absorption rates. All study participants showed significant (vitamin absorption) improvement by drinking Willard Water over the 30-day period. Staninger observed that Willard Water was effective in increasing absorption rates of fat-soluble vitamins such as vitamins E and K. However Staninger also found the most benefits when Willard Water is consumed with water-soluble vitamins such as those in the B complex group. ... the collective specimen pool of individuals showed significant improvement due to Willard Water s micelle reactive properties which allows molecules to become smaller and more effective in the reaction with other molecules opposing charges Staninger continued. It was also observed that the vitamins that were hydrogen reactive reacted significantly better with Willard Water. A second series of studies begun in October of 2012 and near completion is being conducted by NIS Labs in Klamath Falls OR. These studies involve cell cultures and focus on examining the role Willard Water plays in cellular delivery absorption and utilization of antioxidants. While the study results have only recently been submitted for peerreviewed publication it s safe to say that they indicate Willard Water is affecting cellular absorption and utilization of antioxidants. Willard Water has been studied for more than 40 years and these recent studies support what has been learned over the last four decades. Those individuals who have problems with bioavailability of nutrients or simply want better utilization of their vitamins minerals and antioxidants would be well served by making Willard Water part of their daily regimen. For more information visit at WWW.VITAMINRETAILER.COM MAY 2015 44 VITAMIN RETAILER 2015 ScienceofSupplements SUMMERISSUE Essential Formulas Inc. 1861 Valley View Ln. 180 Farmers Branch TX 75234 Phone (972) 255-3918 Lactobacillus fermentum ME-3 an Exclusive Probiotic Strain With Powerful Antioxidant Activity Mechanisms of Glutathione Support and Potential Applications E ssential Formulas Incorporated (EFI) announces the launch of the new Reg Activ line of products containing the glutathione-boosting probiotic Lactobacillus fermentum ME-3. Lactobacillus fermentum ME-3 was discovered in 1995 when it was isolated from the intestinal tract of a healthy oneyear-old child. Twenty years of research has provided deep insight into the following wide-ranging biological and health benefits of ME-3. Lactobacillus fermentum ME-3 increases glutathione levels. Scientists are calling ME-3 a complete glutathione system because is produces the antioxidant via three different mechanisms 1) ME-3 produces glutathione 2) it can extract glutathione from the environment and 3) it can regenerate or recycle oxidized glutathione back to its active or reduced state. Glutathione acknowledged as the Master Antioxidant is the most prevalent and important antioxidant in the human body. Glutathione is produced in virtually every cell of the body but levels decline dramatically with age. Free radical damage and exposure to environmental toxins also contribute to declining glutathione levels. Because ME-3 increases glutathione levels it provides powerful antioxidant protection and helps slow down the aging process. ME3 also produces MD-SOD which is another important antioxidant in humans which provides additional antioxidant and anti-aging support for people of all ages. Oxidized LDL-cholesterol damages endothelial which results in plaque build-up and increased risks for cardiovascular events. Since ME-3 provides increased antioxidant support from both glutathione and Mn-SOD it lowers oxidation of LDL-cholesterol thus risks for cardiovascular actions. Glutathione and glutathione-containing enzymes like glutathione peroxidase and glutathione reductase play critical MAY 2015 WWW.VITAMINRETAILER.COM roles in detoxification. Since ME-3 produces glutathione it will aid in the detoxification of a wide range of toxins including some heavy metals agricultural pesticides and air pollutants. The liver is the primary organ of detoxification and glutathione is the most important detoxifying compound. Tissue glutathione levels in the liver are higher than any other location. Both toxins and free radical damage accelerate liver damage. Since ME-3 produces glutathione it will enhance the liver s detoxification capabilities and reduce free radical damage. ME-3 increases the activity of paraoxonase enzymes which detoxify organophosphates one of the most widely used classes of pesticides commonly sprayed on commercial food crops and are present in many pesticide and insecticide products used in homes and gardens. Glutathione is also critical for the detoxification of mycotoxins and exposure is far more common that most people realize. In addition to environmental exposure to mold many foods are regularly found to contain traces of mycotoxins such as grains fruits peanuts and coffee. Mycotoxins are highly toxic to the lungs liver brain and weakens the immune system. Since ME-3 produces glutathione it will likely help the body detoxify mycotoxins. Lactobacillus fermentum ME-3 provides substantial benefits in multiple ways which include increased levels of antioxidant activity detoxification support for liver heart and the immune system. With its wide range of documented benefits Lactobacillus fermentum ME-3 qualifies as one of the strongest multi-function probiotics ever discovered. The new Reg Activ Formulation containing Lactobacillus fermentum ME-3 1. Reg Activ Liver & Detox Health contains ME-3 along with selenium methionine milk thistle and N-acetylcysteine. 2. Reg Activ Cardio Wellness contains ME-3 along with CoQ10 N-acetylcysteine and vitamins B1 B5 B6 and B12. 3. Reg Activ Immune & Vitality contains ME-3 along with vitamins B1 B2 B3 B6 C carnitine and Lactobacillus Brevis KP08. Product Note Compatibility of Reg Activ and Dr. Ohhira s Probiotic. As a part of its education activities EFI underscores that Dr. Ohhira Probiotics and Reg Activ are not rival products. On the contrary they are extremely synergetic products but with differing commitments. They can safely be consumed separately or in combination. Consumers seeking restoration and enhancements of the GI (gastrointestinal) tract cannot find a better product than Dr. Ohhira Probiotics. A properly functioning digestive tract is critical for optimal functioning of the immune system and overall good health. Reg Activ products containing Lactobacillus fermentum ME-3 address condition specific requirements by increasing the production of glutathione and adding other ingredients for a synergistic health promoting benefit. Dr. Ohhira s Probiotics and Reg Activ can be taken simultaneously or separately. Taking a Reg Activ formula in conjunction with Dr. Ohhira s Probiotics will provide optimal proactive health. For a full list of references visit VITAMIN RETAILER 45 2015 ScienceofSupplements SUMMERISSUE Life Extension 3600 W. Commercial Blvd. Fort Lauderdale FL 33309 Phone (888) 884-3657 Email generalquestions Website AMPK The Cellular Enzyme That Promotes Longevity and Reduces Fat Storage or 30 years scientists have been investigating the properties of a youth-promoting enzyme called AMPK which is a master switch 1 that in many ways controls how our cells behave. Extensive research shows that by increasing AMPK activation we can reduce many of the destructive factors of aging thus enabling cells to return to their youthful vitality. In youth AMPK is more activated2 and helps protect against obesity3 and diabetes.4 But as we grow older cellular AMPK activation decreases weight gain often follows and we are more likely to succumb to the destructive factors of aging.5-7 Scientists view the discovery of AMPK as a major advance in how we understand and combat aging. By reactivating cellular AMPK we move closer to gaining meaningful control over deadly aging processes such as excessive weight gain that predispose us to so many degenerative disorders. Increased AMPK activation has been shown to help reduce fat storage (especially dangerous belly fat) increase insulin sensitivity (to lower blood glucose) reduce cholesterol triglyceride production and suppress chronic inflammation.6 8 F activated by normal AMPK function.6 For example p53 is a tumor-suppressing gene that inhibits uncontrolled cell propagation. Without AMPK these longevity genes fail to perform their duties potentially resulting in premature death.6 18 Fortunately research demonstrates that when AMPK signaling is boosted these deteriorating processes are reversed19 restoring more youthful metabolism and preventing related chronic diseases. The Beneficial Effects Of Restoring AMPK When AMPK is increased the body kicks into high gear and functions with youthful vitality. Activated AMPK helps remove excess glucose and fats burning them for energy instead of depositing them in the belly and elsewhere.20 21 To support all this increased fat burning cells manufacture new mitochondria in a process known as mitochondrial biogenesis.22 These newly created mitochondria burn fuel more cleanly and efficiently than older worn-out mitochondria23 resulting in a higher energy output for the entire body.24-26 The net effects of AMPK activation closely resemble those of calorie restriction and vigorous exercise. This occurs because both calorie restriction and vigorous exercise activate AMPK in response to energy needs that exceed supply. (Exercise may not increase AMPK in elderly individuals).4 The Chinese herb Gynostemma pentaphyllum27 and trans-tiliroside derived from rose hips28 are two naturally sourced extracts which uniquely increase AMPK activation without drugs severe calorie restriction or exercise. Each of these agents triggers different downstream metabolic benefits and in one study trans-tiliroside led to an even greater glucose-lowering effect than the AMPK-activating antidiabetic drug metformin.29 Studies show that these supplements significantly reduce risky belly fat accumulation promote weight loss normalize blood sugar improve insulin resistance and lower serum lipid levels. Activation of the AMPK enzyme is a critical component in warding off degenerative disease. By activating cellular AMPK we provide our body with the opportunity to reverse physical and mental decline associated with aging buying us time to take advantage of future longevity breakthroughs that will markedly extend healthy human lifespans. References 1 Am J Physiol. 1999 Jul 277(1 Pt 1) E1-10. 2 Exp Gerontol. 2014 Jul 55 120-8. 3 J Biol Chem. 2010 Jun 18 285(25) 19051-9. 4 Am J Physiol Endocrinol Metab. 2009 297 E956 E64. 5 Age (Dordr). 2012 34(1) 157-68. 6 Ageing Res Rev. 2012 Apr 11(2) 230-41. 7 J Obes. 2011 2011 252817. 8 Circ Res. 2007 Feb 16 100(3) 328-41. 9 Physiol Rev. 2009 89 1025-78. 10 Crit Rev Biochem Mol Biol. 2010 Aug 45(4) 276-95. 11 Basic Res Cardiol. 2013 May 108(3) 329. 12 Essays Biochem. 2010 47 69-84. 13 EMBO J. 2011 Feb 16 30(4) 634-5. 14 PLoS Genet. 2014 Apr 24 10(4) e1004273. 15 Autophagy. 2012 Sep 8(9) 1401-3. 16 Cell Signal. 2014 Jan 26(1) 1-8. 17 Science. 2011 331 456-61. 18 J Mol Med. 2011 89(7) 667-76. 19 Age (Dordr). 2014 Apr 36(2) 641-63. 20 Endocrinology. 2012 May 153(5) 2130-41. 21 Exp Physiol. 2012 May 97(5) 603-17. 22 Proc Natl Acad Sci USA. 2002 Dec 10 99(25) 15983-7. 23 Biol Chem. 2013 Mar 394(3) 393-414. 24 Exp Gerontol. 2013 Jan 48(1) 55-63. 25 Clin Sci (Lond). 2013 Apr 124(8) 491-507. 26 Aging Cell. 2010 Aug 9(4) 592-606. 27 Biotechnol Lett. 2012 Sep 34(9) 1607-16. 28 Prev Nutr Food Sci. 2013 Jun 18(2) 85-91. 29 J Ethnopharmacol. 2011 May 17 135(2) 515-21. WWW.VITAMINRETAILER.COM MAY 2015 The Dangers Of Reduced AMPK When we are young AMPK keeps our metabolic functions running smoothly. But as we age AMPK signaling declines which may quickly lead to an excess buildup of blood glucose chronic inflammation6 9 10 and dangerous fat accumulation.6 Another deadly impact of reduced AMPK activation is a decreased number of functional mitochondria11 12 and the accumulation of cellular garbage6 13 14 which eventually renders cells nonfunctional.15-17 Scientists continue to discover that many of the known biochemical longevity factors (such as SIRT1 FoxO and p53) are 46 VITAMIN RETAILER 2015 ScienceofSupplements SUMMERISSUE Nordic Naturals 111 Jennings Dr. Watsonville CA 95076 Phone (800) 662-2544 Fax (831) 724-6600 Email info Website Omega-3 Nutrition The Single Most Important Part of Your Pregnancy T he demands placed on a woman s body during pregnancy and birth far exceed what most women will ever experience during any other time in their lives. While pregnancy itself is not considered a medical condition under normal circumstances some pregnancy-related conditions may indeed require medical supervision and even intervention. Nutritional choices made prior to and during gestation will have farreaching consequences which affect not only mother s health but baby s as well. Often overlooked is the truth that some of the most common and frequently occurring pregnancy complications can be avoided by simple dietary modifications. Just as a strong and beautiful tree growing in ideal conditions will produce the healthiest fruits a woman whose nutritional needs are met completely during pregnancy will significantly lessen the potential for complications and interventions throughout the gestational and delivery process. The importance of proper nutrition during this time cannot be overstated. Unfortunately most of the attention given to a pregnant woman s diet and nutrition centers merely around weight gain and postpartum weight loss but the conversation could and should be so much more. Sufficient omega-3 levels in the diet and the body during pregnancy have vast evidence in the scientific literature supporting healthy blood pressure ranges healthy weight gain achieving a full-term gestational period and even supporting a healthy mood post-partum. Essential omega-3s particularly DHA are critical for ensuring proper fetal development particularly neurological wellbeing. Most people tend to be highly deficient in these beneficial fats throughout their lifetime MAY 2015 WWW.VITAMINRETAILER.COM Sufficient omega-3 levels in the diet and the body during pregnancy have vast evidence in the scientific literature supporting healthy blood pressure ranges healthy weight gain achieving a full-term gestational period and even supporting a healthy mood post-partum. even without the added demands of pregnancy. Women in particular tend to selectively accumulate and store omega-3 fats in their gluteo-femoral tissue across their lives during pregnancy and lactation these are mobilized and delivered via placenta or breast milk to the fetus or nursling. It is worth noting that countries with the highest fish consumption such as Japan and Norway also experience some of the lowest rates of post-partum depression. In fact there is so much scientific evidence supporting the need for high omega-3 levels before during and after pregnancy that the U.S. Food and Drug Administration and Environmental Protection Agency recently drafted a recommendation suggesting women increase fish intake during pregnancy countering long-held warnings against fish consumption for pregnant women due to concerns about mercury. Even with high fish intake however it s difficult to achieve large enough levels of omega-3 from sources like salmon and sardines. For this reason many women have better success supplementing with high-quality fish oils to meet their essential omega-3 needs. Nordic Naturals Prenatal DHA is the official omega-3 of the American Pregnancy Association providing 450 mg DHA per serving which generously fulfills international recommendations for daily DHA intake for pregnant women. It also contains 400 IU of natural vitamin D3 for added mood support. This supplement is appropriate to take before and during pregnancy and throughout breastfeeding. Everyone can agree that a healthy baby and healthy mama are the ultimate objective of pregnancy and childbirth. Key to this is making the best nutritional choices possible and finding a prenatal care provider who can provide expertise on these matters. Remember You are what you eat doesn t apply to just you when you re eating for two. With every food choice you make you have the power to contribute to the health of you and your baby and to give your little one the best start in life possible. What could be better than that Eliza Leggatt--As a writer educator and frequent featured radio guest for Nordic Naturals Leggatt focuses on the topic of maternal and neonatal health as they relate to omega-3 deficiency. Leggatt empowers others on their health journeys with compassion candor and a unique ability to convey complex scientific principles in a down-to-earth accessible manner. In addition she is working on her first children s book. VITAMIN RETAILER 47 2015 ScienceofSupplements SUMMERISSUE North American Herb & Spice 13900 W. Polo Trail Dr. Lake Forest IL 60045 Phone (800) 243-5242 Fax (847) 473-4780 Email info Website Wild Spice Oils and Mountain Spices as Bone-building Agents W ild mountain-grown spices of Mediterranean source are surely among the most potent natural substances known. These spices have powers which are exceedingly unique. Revealingly they have a predilection for growing on mountain rock specifically calcareous or calcium- and phosphaterich rock. They prefer it over dirt-like soil. In fact these spices fail to grow in mere farm-type soil. These wild spices break down the rock fixing it into the earth while aggressively absorbing the mineral matter into the plant substance. A high density of the rock-based minerals is found in mountain spices such as wild oregano rosemary and sage particularly calcium phosphorus copper iron magnesium zinc and manganese all of which are needed for the building of healthy bone. Consider wild oregano and its calcium content. It is quite considerable. Ground wild oregano provides some 30 mg of calcium per teaspoon. Two teaspoons thus amount to approximately 6 percent of the daily requirement. Few other foods have such a density. Biologically available calcium is essential for supporting the growth and repair of healthy bones and teeth. A diet rich in vegetable-source calcium is associated with retardation of bone loss. Wild oregano sage and rosemary are all dense sources of biologically available calcium. Additionally from a nutritional point of view spices particularly wild oregano and rosemary are rich sources of vitamin K also needed for bone remodeling. A mere teaspoon of ground oregano contains 11 mcg of the vitamin nearly 9.5 percent of the daily requirement for men and 12.5 percent for women. Vitamin K is essential for the development of strong bones and is also needed for the synthesis of blood coagulation proteins. A deficiency of this nutrient increases the risk for the development of osteoporosis and bone fractures as well as a tendency for excessive bleeding upon injury. Does this mean then that wild mountain-found spices can build bone 48 VITAMIN RETAILER Modern research tends to confirm this. This was first revealed by Switzerland s R.C. Muhlbauer who found that wild high-mountain spices as well as their oils are the most potent bone-building and osteoporosis-retarding agents known. The primary mountain spices which exerted this effect were wild rosemary sage and wild oregano (mentioned in the study as thyme ). It was Muhlbauer and his group publishing in the Journal of Nutrition who also found that the essential oils of such spices block bone loss. Medically this is known as inhibition of bone resorption. The powers of spice oils and whole spices were dramatic and it was beyond statistically significant how they blocked bone loss and even resulted in building denser bones. Initially Muhlbauer found that sage strongly inhibited bone resorption. This then led him to study other spices notably rosemary and oregano as well as the extracted oils of such spices. What he found was nothing less than astounding. Within 30 minutes the oils were found to block bone loss indicating that in fact bone loss in humans could well be reversible. Merely added to the food they discovered the spices and their oils inhibited bone resorption in rats. In yet another study of some 50 foods only 23 were found to be effective in blocking bone loss and in potentially building bone. Of these oregano (also known as wild thyme) rosemary sage onion and garlic were found to be most powerful. One wild oregano capsule on the market also contains garlic and onion and thus fits the findings of this study. Regarding oregano in particular additional compelling research has been conducted once again by Swiss along with German investigators. Researchers publishing in Proceedings of National Academy of Sciences discovered that oregano the whole crude spice is entirely unique in its actions on bones and the inflammation associated with bones and joints. The spice contains a potent substance known as beta caryophyllin (E-BCP) which not only reduces inflammation but also helps reduce the risk of osteoporosis. This substance also found in rosemary and basil effectively inhibits inflammation according to one of the lead researchers Prof. Andreas. The research was conducted on mice with swollen paws. The oregano active ingredient eliminated the swelling in some 70 percent of the test animals matching standard pharmaceutical agents. Once again because they contain similar properties oregano combined with rosemary and sage would potentiate this benefit. E-BCP affects what are known as cannaboid CB2 receptors found in the cell membranes. When they are triggered pain and inflammation are reduced. The substance proved so powerful that the investigators dubbed it the ultimate inflammation fighter. For a full list of references visit WWW.VITAMINRETAILER.COM MAY 2015 2015 ScienceofSupplements SUMMERISSUE NOW Foods 244 Knollwood Dr. Bloomingdale IL 60108 Phone (888) 999-8069 Fax (630) 790-8019 Email customerservice.dept Website NOW Foods New Eggshell Membrane (NEM) By Nena Dockery Technical Services Manager Stratum Nutrition OW Foods is launching a highly effective product into the joint health category--eggshell membrane featuring the branded ingredient NEM. NEM brand eggshell membrane is a wholefood source ingredient that can help to maintain healthy articular cartilage and the surrounding synovial tissue by nourishing joints as well as by supporting a balanced immune response to typical daily wear and tear. The recommended dose of NOW s Eggshell Membrane is only ONE 500 milligram capsule of NEM daily. NEM is a unique multi-patented U.S.domestic ingredient made from U.S. Department of Agriculture (USDA) inspected egg breaker shells and cGMP (current good manufacturing practice) manufactured in the Midwest. This translates into a highly sustainable traceable ingredient from farm to supplement. NEM is the most researched eggshell membrane ingredient for joint health backed by multiple published studies highlighting its exceptional safety and benefits to joints and the surrounding soft tissue. It is primarily composed of fibrous proteins including collagen types I V and X as well as glycosaminoglycans such as chondroitin sulfate and hyaluronic acid. All of these nutrients occur naturally within NEM--a complete solution for supporting joint health safely. The efficacy of NEM is supported by two open-label pilot clinical studies and N one multicenter randomized doubleblind placebo-controlled human clinical trial demonstrating that a once daily 500 mg dose of NEM significantly improves normal joint comfort and flexibility.1 2 In the open-label studies a significant reduction in pain was noted at both seven- and 30-day evaluations. In the RCT study the evaluations occurred at 10 30 and 60 days with significance at the 10-day time period and continuation of the positive trend throughout the 60day study period. No evaluations were made in either study at earlier time periods so it is possible that the beneficial effects might have had statistical significance sooner than seven to 10 days in the treatment period. Furthermore an independent multicenter open-label clinical trial conducted in Germany was published in 2014 reaffirming the findings from the U.S. studies.3 This study demonstrated that one 500 mg dose day of NEM significantly reduced occasional pain in individuals with age-related knee or hip wear and tear both rapidly and continuously with no notable side effects. Augmenting the results of these efficacy studies are three studies detailing a potential mechanism of action for NEM s benefits. The first was an in-vitro human cell culture study which provided preliminary evidence that NEM exerts an immunomodulatory effect on the uncontrolled release of specific cytokines such as TNF-.4 These findings were then supported by results from an animal study revealing that oral supplementation of NEM can influence both earlyphase and later-phase cytokines involved in normal tissue reactivity.5 The third and most recent study on NEM s mechanism of action was an in-vitro study assessing how various eggshell membrane proteins might impact the gene transcription factor NF-kB in human cell cultures.6 NF-kB plays a fundamental role in the normal functioning of the immune system and occurs very early in the cascade related to tissue response to occasional stress. NEM s ability to affect NF-kB may help to explain the joint health-supporting effects observed in the clinical setting. From individuals who engage in regular sports or athletic endeavors to those who simply want to remain active into middle-age and beyond NOW s Eggshell Membrane can be an important addition to any daily supplement regimen. References 1 Ruff KJ et al Eggshell membrane A possible new natural therapeutic for joint and connective tissue disorders. Results from two open label human clinical studies. Clin Interv Aging (2009) 4 235-240. 2 Ruff KJ et al Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee A randomized multicenter double blind placebo controlled clinical study. Clin Rheumatol (2009) 28 907-914. 3 Danesch U et al NEM brand eggshell membrane effective in the treatment of pain associated with knee and hip osteoarthritis Results from a sixcenter open-label German clinical study. J Arthritis (2014) 3 3. 4 Benson KF Ruff KJ and Jensen GS Effects of natural eggshell membrane (NEM) on cytokine production in cultures of peripheral blood mononuclear cells increased suppression of tumor necrosis factor-levels after in vitro digestion. J Med Food (2012) 15(4) 360368. 5 Ruff KJ and DeVore DP Reduction of pro-inflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membranederived product. Mod Res Inflamm (2014) 3 19-25. 6 Ruff KJ et al Eggshell membrane hydrolyzates activate NF- B in vitro possible implications for in vivo efficacy. J Inflamm Res (2015) 8 49-57. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. MAY 2015 WWW.VITAMINRETAILER.COM VITAMIN RETAILER 49 2015 ScienceofSupplements SUMMERISSUE Pharmachem Laboratories Inc. 265 Harrison Ave. Kearny NJ 07032 Phone (800) 526-0609 (201) 246-1000 Fax (201) 246-8105 Email info Website Healthy Weight Loss Carbohydrate Absorption Inhibition Addresses Modern Lifestyles he WHO (World Health Organization) has identified a global shift in diet towards increased intake of energy-dense foods that are high in fat and sugars but low in vitamins minerals and other micronutrients. One recent study published in the Annals of Internal Medicine concluded that a low-carb diet was superior to a low-fat diet for the 148 people of diverse ethnicities who participated in the study. The participants on the lowcarb diet not only had a more significant decrease in weight (8 pound average) but also reduced their cardiovascular risk factors compared to those on the low-fat diet. A second study published by the Journal of American Medical Association compared 48 previous studies including a total of 7 286 overweight and obese adults that confirmed the largest weight loss was with low-carbohydrate diets. Weight loss differences between individual diets were minimal and on average participants sustained a 16-pound reduction after a year. T One recent study published in the Annals of Internal Medicine concluded that a low-carb diet was superior to a low-fat diet for the 148 people of diverse ethnicities who participated in the study. of Phase 2. Three studies demonstrated significant loss of body weight with Phase 2 compared to a placebo control in people who are overweight or obese. The doses ranged from 445 mg for 4 weeks to 3000 mg for 8 to 12 weeks.1-3 A placebo controlled study by showed a comparative loss in body weight only when subjects were stratified by dietary carbohydrate intake. Those who consumed the greatest amount of carbohydrate lost significant body weight in comparison to the placebo group.4 Six additional studies reported a loss of weight over time.5-10 Three clinical studies reported a reduction in serum triglycerides over time.6 7 10 In a double-blind 123-participant study published in the peer-reviewed journal Obesity participants taking Phase 2 lost an average of 7 pounds in 12 weeks in addition to significant loss of body fat mass and weight circumference compared to the placebo group. Additionally 73.5 percent of participants maintained their body weight for 24 weeks and reported decreased desire in sugary food cravings. This study is the longest single clinical study conducted on Phase 2 white kidney bean extract.11 To date these findings confirm that Phase 2 not only reduces the absorption of calories from carbohydrates but also helps to reduce food cravings for sweet foods and chocolates. This contributes greatly to the success of the weight loss regimen as well as a happy and alert lifestyle. Scientific Evidence of Efficacy Clinical studies demonstrate that a proprietary white bean extract (Phase 2) has the ability to reduce the post-prandial spike in blood glucose levels. Experiments conducted incorporating the extract into food and beverage products have found that it can be integrated into various consumables without losing activity or altering the appearance texture or taste of the food. There have been no serious side effects reported following consumption of the extract. Gastrointestinal side effects are rare and diminish upon extended use of the product. In totality research demonstrates that the extract has the potential to induce weight loss and reduce spikes in blood sugar caused by carbohydrates through its alpha-amylase inhibiting activity. Overall approximately a dozen clinical studies have demonstrated weight loss over time following administration 50 VITAMIN RETAILER References 1 Celleno L et al Int J Med Sci 2007 4 45-52. 2 Rothacker D. pdf Phase2_Study6.pdf. 2003. Leiner Health Products. 3 Wu X et al. Journal of Applied Research 2010 10 73-79. 4 Udani J Singh BB Altern Ther Health Med 2007 13 32-37. 5 Thom E J Int Med Res 2000 28 229-233. 6 Erner S Meiss D. pdf Phase2_Study8.pdf . 2003. 7 Koike T et al J New Rem & Clin (Japanese) 2005 54 1-16. 8 Osorio L Gamboa J. pdf Phase2_Study10.pdf Internal Report. 2005. 9 Yamada J et al. pdf Phase2_Study15.pdf. 2007. 10 Udani J et al Altern Med Rev 2004 9 63-69. 11.Grube B. et al. Obesity 2013. WWW.VITAMINRETAILER.COM MAY 2015 2015 ScienceofSupplements SUMMERISSUE Rainbow Light Nutritional Systems 100 Avenue Tea Santa Cruz CA 95060 Phone (800) 635-1233 Website Allergy Rescue llergy Rescue is part of the Rainbow Light s cutting edge line of integrated health therapies developed to address the top health concerns of consumers. It is formulated to address immune defense associated with the allergy response. Allergies affect one in five Americans and approximately 40 million Americans have indoor outdoor allergies as their primary allergy. The term allergy refers to the immune system inappropriately attacking a substance in the body that is not normally harmful. The immune system has many different tools at its disposal to combat potential disease-causing substances in the body such as bacteria and viruses. The type of immune response that is relevant to the airborne allergy response is the specific (or acquired) defense mechanism whereby each individual obtains the ability to defend against specific pathogens by prior exposure to those pathogens. This response involves the production of antibodies that attack and destroy foreign allergens (or antigens). The cells that produce antibodies are a special type of white blood cell called lymphocytes. The type of lymphocyte that is involved in the production of antibodies is known as the B lymphocyte. B lymphocytes secrete antibodies specific to each pathogen. The antibodies attach onto the allergen and A Allergies affect one in five Americans and approximately 40 million Americans have indoor outdoor allergies as their primary allergy. then prepare it for destruction by neutrophils and macrophages which use phagocytosis (cellular eating) to destroy the allergen. Antibodies thus identify the targets for destruction they do not kill the allergens themselves. Meanwhile as the pathogen is being destroyed substances are discharged that stimulate the release of histamines from mast cells. Histamine brings more blood flow to the area along with more phagocytes and is responsible for the swelling heat and inflammation that occur during this process. Although histamine is an important step in the immune defense if the B lymphocytes respond in an abnormal way to non-pathogenic substances (such as what happens with airborne allergy sufferers) the histamine response will create chronic symptoms of inflammation in the body. Inappropriate response of the B lymphocytes to allergens therefore leads to excess histamine release and an immediate allergic response. Allergy Rescue is a naturally effective integrative health therapy designed to Inhibit allergic response to indoor outdoor triggers with quercetin vitamin C and bromelain to moderate the release of excess histamine following exposure to environmental irritants. Ease occasional allergy discomforts including runny nose itchy eyes and skin irritations with herbs traditionally targeted to support clear nasal passageways and normal mucous production. Allergy Rescue is a flexible solution you can take 1-3 tablets once or twice daily depending on individual needs. References 1 display.cfm id 9&sub 30. 2 Sharma SC Wilson CW. The cellular interaction of ascorbic acid with histamine cyclic nucleotides and prostaglandins in the immediate hypersensitivity reaction. Int J vitam Nutr Res. 1980 50(2) 163-70. 3 Johnston CS Martin LJ et al. Antihistamine effect of supplemental ascorbic acid and neutrophil chemotaxis. J Am Coll Nutr. 1992 11 172-6. These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. VITAMIN RETAILER 51 MAY 2015 WWW.VITAMINRETAILER.COM 2015 ScienceofSupplements SUMMERISSUE Redd Remedies 211 S. Quincy Ave. Bradley IL 60915 Phone (888) 453-5058 Fax (815) 614-2084 Website Joint Health ... Real Results T here are about 360 joints in the human body. With so many moving parts it s no wonder that 75 million Americans deal with arthritis and joint disease. Forty-two percent of adults 45 to 64 years of age and half of adults 65 and older experience joint pain but joint pain isn t isolated to Baby Boomers and seniors. In the 2009 CDC (Centers for Disease Control and Prevention) National Health Interview Survey one in five adults between the ages of 18 and 44 reported experiencing joint pain within the past 30 days. Musculoskeletal diseases are the most common health issue in the United States. The complexity of the joint structure can range from the simplistic synovial joint of the finger to the largest joint in the body--the knee joint. Regardless of whether it s a finger an elbow or a knee these body parts are vulnerable to the effects of wear and tear. Over time the cartilage that cushions joints becomes stiff and loses its fluidity or natural flexibility. Eventually the cartilage can breakdown and wear away causing the bones to rub directly together which our bodies naturally react to with inflammation. This friction can create substantial pain making normal activities more difficult. New discoveries in the natural approach to joint health can help combat this friction by providing the body with the nutrients the joints need to remain healthy and botanicals to support healthy inflammation management. NEM is a joint health 52 VITAMIN RETAILER ingredient derived from the membrane or the inner lining of eggshells. That membrane contains naturally occurring glycosaminoglycans such as chondroitin collagen glucosamine hyaluronic acid and other proteins and amino acids essential to the joint tissue. All of these nutrients are packed in that eggshell membrane which makes NEM a whole foodbased ingredient unlike glucosamine which is an isolated highly concentrated ingredient normally derived from shellfish. Multiple human clinical trials have shown NEM s effectiveness for joint health. Not only have these studies proved effectiveness they have also shown that NEM provides relief quickly. Open label trials of NEM showed that a single 500 mg dose decreased pain by 25 percent in as little as seven days and increased flexibility by 44 percent by trial s end NEM decreased pain associated with joint range of motion by 76 percent.1 A double-blind placebo controlled trial verified the effectiveness of NEM for joint health. With the same once daily 500 mg dose of NEM an average 31 percent reduction in stiffness was demonstrated in the treatment group in just 10 days furthermore one-third of the patients experienced a greater than 50 percent reduction in pain by trial s end.2 Overall the study demonstrated an increase for individuals in joint comfort flexibility and range of motion.3 Studies on NEM have also shown that this complex of naturally occurring glycosaminoglycans reduces both early-phase and late-phase pro-inflammatory cytokines the chemical messengers responsible for inflammation.4 In the world of over-thecounter and prescription drugs for osteoarthritis comes unwanted side effects such as a higher risk of gastrointestinal issues and even cardiovascular issues. This is not the case with NEM Natural Eggshell Membrane. Only NEM has an established safety record. In all of the human studies no serious adverse events were reported. NEM has even been studied at 50 times the clinically effective dose with no toxicity demonstrated. The proven efficacy of NEM for joint health and function paired with its established safety record establish this unique ingredient as a viable option for those individuals looking to protect and establish healthy moving joints. References 1 Ruff K.J. DeVore D.P. Leu M.D. Robinson M.A. (2009). Eggshell membrane A possible new natural therapeutic for joint and connective tissue disorders. Results from two open-label human clinical studies. Clinical Interventions in Aging 4 235-240. 2 Ruff K.J. Winkler A. Jackson R.W. DeVore D.P. & Ritz B.W. (2009). Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee A randomized multicenter double-blind placebo- controlled clinical study. Clinical Rheumatology 28 907-914. doi 10.1007 s10067-009-1173-4. 3 Ruff K.J. Winkler A. Jackson R.W. DeVore D.P. & Ritz B.W. (2009). Eggshell membrane in the treatment of pain and stiffness from osteoarthritis of the knee A randomized multicenter double-blind placebo- controlled clinical study. Clinical Rheumatology 28 907-914. doi 10.1007 s10067-009-1173-4. 4 Ruff K.J. DeVore D.P. (2014). Reduction of proinflammatory cytokines in rats following 7-day oral supplementation with a proprietary eggshell membrane-derived product. Modern Research in Inflammation 3 19-25. http 10.4236 mri.2014.31003. WWW.VITAMINRETAILER.COM MAY 2015 2015 ScienceofSupplements SUMMERISSUE Scandinavian Formulas Inc. 140 E. Church St. Sellersville PA 18960 Phone (215) 453-2507 (215) 257-9781 Email info Website Stop Snoring With Nozovent and Open Nasal Passages From the Inside breathing. Petruson calculated that a small increase in the opening or ventilation of the nasal passages would reduce by as much as one-half the pressure being applied to the vibrating skin. Less pressure on the nose equals less noise from the nose This ventilation from the springboard action of the Nozovent is crucial because during sleep the soft tissues and muscles of the mouth and throat relax narrowing the breathing airways into a virtual wind tunnel. This decrease in the airway space increases the velocity of the air flowing through this tunnel. As the velocity of the air flowing through this tunnel increases the soft tissues in this nasal wind tunnel begin to vibrate with each breath. In physics any gas has a certain pressure by virtue of its The Physics of Snoring weight. When the gas presses against As an ENT (ear nose and throat) a surface it creates a pressure on that physician Petruson used some fascisurface. nating principles of physics to create Petruson realized that with the his remarkable little device. The gentle springboard action of a propsound of snoring is actually created erly designed plastic device the by the vibrations of the palate and nasal passages could be opened sufsoft tissue of the throat. A simpler ficiently to actually reduce the vibratless delicate way of describing this ing turbulence at the entrance to phenomenon is that snoring occurs our respiratory system. when dangling tissue vibrates during Although the average Ranking Snoring With Barking Dogs And Other Bad Vibes intensity of 10 decibels Waves lapping gently on the shore snoring is 80 40 decibels Normal conversation of the human voice decibels the range is 60 decibels Baby crying quite wide. 80 decibels Snoring Following is 80 decibels Barking dog a rating scale that is gener80 decibels Motorcycle ally used by 100 decibels Lawn mower U.S. family 120 decibels Rock and roll band physicians as 130 decibels Pain level for most people well as those I f a loved one says they are giving you a gift from Sweden you may start fantasizing about driving a Volvo or Saab--or relaxing in new Ikea furniture after a Swedish massage. However if you snore your true pleasure could come from a remarkably simple anti-snoring device invented by Swedish physician Dr. Bjorn Petruson of the University Medical Hospital in Goteborg. Now available in the United States The Nozovent is made of clear flexible plastic and inserted inside the nose. The Nozovent s design consists of a plastic bar each end of which ends in a tab to be placed inside each nostril. When inserted it uses an outward springboard action to gently dilate each of the nostrils. The Nozovent is an internal nasal dilator as opposed to the external nasal strips that apply less of the pressure needed to open nasal passages. who treat snoring. While You Were Sleeping Mild snoring You snore occasionally often when you are lying on your back or when you ve consumed an alcoholic drink or two. Moderate snoring You snore frequently no matter what position you sleep in. Severe snoring You snore very loudly in all body positions for most of the night. You make enough noise to be audible in the next room without a microphone. Heroic snoring You snore very loudly and constantly in all body positions so that you are audible from three or four rooms away without a microphone. (It is interesting to note that all the snorers whatever their category will snore loudest in the summer because it is in the summer that we are most relaxed ) The Nozovent has been shown to be of help for members of each of the snoring categories from mild to heroic. So impressed with the results of the Nozovent nasal dilator two Japanese scientists1 set out to determine if the same device would be as effective on the Japanese. Their conclusion The Nozovent device produces a unique method of nonsurgical treatment of snoring and the effectiveness is a result of the dilation of the nasal valve area. The principle is medically sound and is equally applicable to the nasal valves of both Caucasians and the Japanese who have different external nose structures. The scientists added The Nozovent device has been reported to prevent snoring and sleep apnea. Reference 1 Shinkawa A Sakai M. A Clinical Study Of The Nasal Dilator Nozovent In Japanese Subjects. Tokai J Exp Clin Med. 23(1) 13-7. March 1998. VITAMIN RETAILER 53 MAY 2015 WWW.VITAMINRETAILER.COM 2015 ScienceofSupplements SUMMERISSUE Superior Source CVC Inc. 4510 S. Boyle Ave. Los Angeles CA 90058 Phone (800) 421-6175 Fax (323) 589-6667 Email information Website Silent Killer Simple Solution By Martie Whittekin CCN sk the average woman to name the most serious health threat to women and she will probably say breast cancer. Guys usually think that theirs is heart attacks caused by high cholesterol. But both are wrong. Breast cancer may be top-of-mind but heart disease claims more women than the next seven causes combined. Likewise the billions spent advertising cholesterol-lowering drugs blur the fact that cholesterol numbers are just one controversial aspect of heart health. Half who die from heart attacks had normal cholesterol High cholesterol is associated with increased incidence of heart attacks. However associated with is not a causal relationship. It only means that the two factors often appear together--like fire trucks and house fires. The real question is why does cholesterol go up The body uses cholesterol to make hormones and vitamin D. It is also a repair molecule and many experts believe that cholesterol is the fire truck at the scene of the blaze (damage to arteries). Smoking heavy metals environmental chemicals and toxins released by bacteria in our gums are a few suspected causes of the damage. Cholesterol itself can become an irritant if oxidized and not restored by antioxidants like vitamin E. A big under-recognized cause of inflammation damage to the blood vessels is homocysteine.1 Homocysteine is a naturally occurring amino acid that is a breakdown product of the essential amino acid methionine. Homocysteine elevation is linked to cancer and is a cause of deep vein thrombosis stroke (even in young women) as well as reduced physical performance in older women. The concept of homocysteine as a cardio bad guy has been investigated since at least 1969 with Harvard researcher Dr. Kilmer McCully pioneering the field. We know that as blood lev- A els of homocysteine rise the risk of developing severe coronary heart disease rises proportionately. In one study women with the highest homocysteine measurements (the top 10 percent) had 2.3 times the heart attack risk of women in the lower half of the scale. (The women with high homocysteine levels also tended to have low folic acid levels.) Most nutrition-savvy doctors recommend supplementing with folic acid to help homocysteine normalize as well as B6 and B12 for their well-documented fringe benefits. Normally homocysteine is converted into a harmless amino cysteine or back into methionine. Gluten sensitivity may increase homocysteine buildup but the usual problem is low B vitamins. Most nutrition-savvy doctors recommend supplementing with folic acid to help homocysteine normalize as well as B6 and B12 for their well-documented fringe benefits. Folic acid is crucial for proper cell division and so helps prevent cancer and neural tube birth defects. Low folic acid may account for 40 percent of cases of autism.2 Supplementing B12 with folic is important in part because high blood levels of folic acid can make it harder to detect a vitamin B12 deficiency in routine blood tests. Vitamin B6 has dozens of textbook roles including help- ing nerve function forming red blood cells and utilizing amino acids. It is often employed to reduce PMS symptoms. Stumbling blocks to achieving B vitamin sufficiency include 1. Lack of awareness of the importance. 2. Poor diet. 3. Supplement absorption--especially with the elderly. Stomach acid is required to produce vitamin B12 and seems needed for adequate folic acid absorption too. Those past middle age may already have reduced stomach acid and acid-blocking heartburn drugs make matters worse. 4. Compliance--people do not like to swallow pills. Hopefully retailers can help with No. 1 and 2. I solve No. 3 and 4 problems with my clients by recommending Superior Source s No-Shot Advanced MicroLingual B12 B6 Folic Acid. The tiny pellets dissolve almost instantly and allow the nutrients to go right into circulation under the tongue. Furthermore B12 is in a meaningful dose 2 000 mcg and in its preferred active forms methylcobalamin and adenosylcobalamin (dibencozide). Likewise B6 is pyridoxal 5 -phosphate. No bulky pills to swallow and the tabs taste great. Since humble B6 B12 and folic acid are usually the answer to excess homocysteine there isn t a wildly profitable drug to fund glitzy TV commercials about the issue. Maybe someday a group with the marketing brilliance of the breast cancer charities will take on homocysteine. References 1 McCully KS. Hyperhomocysteinemia and arteriosclerosis historical perspectives. Clin Chem Lab Med. 2005 43(10) 980-986. 2 JAMA. 2013 Feb 13 309(6) 570-7. doi 10.1001 jama.2012.155925. Association between maternal use of folic acid supplements and risk of autism spectrum disorders in children. Sur n P et all. WWW.VITAMINRETAILER.COM MAY 2015 54 VITAMIN RETAILER 2015 ScienceofSupplements SUMMERISSUE Wakunaga of America Co. Ltd. 23501 Madero Mission Viejo CA 92691 Phone (800) 421-2998 x114 Fax (949) 458-2764 Email jlevy Website Kyolic Aged Garlic s Hypertension Benefits Confirmed By Dr. Karen Ried ypertension. It s a primary risk factor for stroke and heart attack--and it affects nearly one in three Americans.1 2 Among those who have been diagnosed with hypertension about half don t have their condition under control.1 Of more concern an estimated 18 percent of those with the condition are unaware that they suffer from high blood pressure.3 That s not surprising since hypertension often has no tangible symptoms. And nearly 30 percent of American adults suffer from pre-hypertension a condition that puts them at risk of developing clinical hypertension.2 While pharmaceuticals can bring the pressure down recent studies show that a daily dose of aged garlic extract (AGE) safely and effectively reduces blood pressure and benefits a number of other cardiovascular risk factors. Findings slated to be presented at the 5th Science of Nutrition in Medicine and Healthcare Conference in Australia provide clear evidence that supplementing with AGE can effectively reduce blood pressure levels. In addition AGE has a positive impact on arterial stiffness. The double-blind placebo-controlled study which was conducted at Australia s National Institute of Integrative Medicine divided 88 patients with uncontrolled hypertension into two groups. One group was given 1.2 grams of AGE daily and the other was given a placebo. H Mean blood pressure was significantly reduced by 5.0 2.1 mmHg (p 0.016) systolic and in responders by 11.5 1.9 mmHg systolic and 6.3 1.1 mmHg diastolic compared to placebo (p 0.001). Central hemodynamic measures tended to improve in the garlic group more than in the placebo group including central blood pressure central pulse pressure mean arterial pressure augmentation pressure pulse wave velocity and arterial stiffness. Trends in beneficial effects of garlic on inflammatory marker TNF total cholesterol LDL cholesterol and apolipoproteins were observed. Aged garlic extract was highly tolerable and acceptable and did not increase the risk of bleeding in patients on blood thinning medication. Another study recently presented at the American College of Cardiology s 64th Annual Scientific Session & Expo lends further evidence to Aged Garlic Extract s ability to lower blood pressure. During the study which was conducted at the Harbor-University of California Los Angeles (UCLA) Medical Center four placebo-controlled double-blind randomized studies were pooled to examine AGEs effect on blood pressure. The studies involved a total of 161 people who were randomized to take either 1 000 mg of AGE or a placebo daily for one year. All of the subjects had their blood pressure checked at the beginning and the end of the study. Testing was also done to determine the progression of coronary artery calcification. One year later the UCLA researchers noted marked reductions in diastolic blood pressure among the participants who took AGE. Coronary artery calcification was also significantly lower in those who had taken the AGE supplements. In fact AGE inhibited the progression of coronary artery calcification an average 1.78 fold compared to the placebo over the course of the study.5 These findings build upon previous research in the journals Maturitas and the European Journal of Clinical Nutrition which found that AGE reduced systolic blood pressure an average of 10.2-11.8 mm Hg compared to placebo leading the researchers to conclude that AGE offers benefits similar to first-line medication used to treat uncontrolled hypertension.6 References 1 CDC Vital signs awareness and treatment of uncontrolled hypertension among adults--United States 2003 2010. mmwr preview mmwrhtml mm6135a3. htm. 2 CDC Deaths Final data for 2009. nchs data nvsr60 nvsr60_03.pdf 3 Yoon SS Burt V Louis T et al. Hypertension Among Adults in the United States 2009 2010. NCHS data brief no 107. Hyattsville MD National Center for Health Statistics. 2012. 4 Ried K Travica N Sali A. Aged Garlic Extract for hypertension and arterial stiffness The AGE at heart trial. Scheduled for presentation at The 5th Science of Nutrition in Medicine and Healthcare Conference. Pullman Melbourne on the Park Australia. May 2-3 2015. 5 Hom C Luo Y Budoff M. The Effects of Aged Garlic Extract on Coronary Artery Calcium Progression and Blood Pressure. Presented at ACC.15 64th Annual Scientific Session & Expo. San Diego CA March 1416 2015. 6 Ried K Frank OR Stocks NP. Aged garlic extract lowers blood pressure in patients with treated but uncontrolled hypertension a randomized controlled trial. Maturitas. 2010 67(2) 144-50. VITAMIN RETAILER 55 MAY 2015 WWW.VITAMINRETAILER.COM 2015 ScienceofSupplements SUMMERISSUE Xlear Inc. 723 S. Auto Mall Dr. American Fork UT 84003 Phone (877) 599-5327 Fax (801) 492-8011 Email sales Website Sweet Summer Relief Summer brings sunshine swimming and grilling--oh and high pollen counts. S ummer is the time for long days great hikes and barbecues--not for being miserable with seasonal allergies. Here s the science behind those summer sniffles and a few tips on natural and effective ways to manage them. April showers have fueled the May flowers while the May flowers have brought the seasonal onslaught for allergy sufferers. Allergy experts say pollen is the most common allergen and affects the most people. Although fully bloomed trees and green grass are wonderful to look at their pollen (among other allergens) can trigger a runny nose itchy eyes mouth breathing and other symptoms once they reach the upper respiratory tract of certain people. Allergies vary by the region in which you live but the high temperatures are usually dominated by grasses and weeds. Some of summers worst offenders include Weeds Russian thistle Sagebrush Grasses Bermuda Blue grasses Pollution wreak havoc for allergy sufferers. Air pollution can compound allergy symptoms because of stronger sunlight and calmer winds during summertime. Clouds of ozone can be created around cities when sunlight nitrogen oxide and hydrocarbons from burning fuel combine in the atmosphere. Mold Indoors pet dander and mold spores are the standard culprits causing allergy problems by filling the air of your bathrooms and basements with their trails. The Asthma and Allergy Foundation of America states there are many types of mold but only a few can trigger allergies such as asthma. Summer allergy symptoms include Runny nose Watery eyes Sneezing Coughing Itchy eyes and nose Mouth-breathing While less discussed some allergies may result in chronic mouth breathing associated with the development of a high arched palate an elevated upper lip and an overbite in young allergy sufferers known as Long Face Syndrome. Children and teens with allergic rhinitis may need braces and or surgery to correct this dental and health compromising issue that has lifetime affects. Allergy sufferers with allergic rhinitis and severe nasal congestion should take prevention measures like using xylitol nasal products. In addition to gently cleansing moisturizing and soothing the sinus and nasal passages xylitol nasal sprays reduce the adherence of allergens (see figure 1). Xylitol in saline creates a hyper-osmotic solution which draws moisture and keeps the nasal passages and sinuses more clean and moist than saline alone.2 Chemical antihistamines or decongestants can leave your airways and sinuses dry which Long Arm of the Lawn Even though certain allergens may not be in your direct area they can travel hundreds of miles in the wind and are easily irritated and extremely vulnerable to external contaminants. Hyperosmolar environments induce histamine release3 causing the surrounding blood vessels to dilate and increase in permeability. This allows fluid and cells of the immune system such as leukocytes and blood plasma proteins to move from the bloodstream to the site of tissue injury or infection where they begin to manage invaders. Natural Summer Allergy Relief Includes Xylitol nasal sprays to protect the delicate sinus tissues Eye drops Keep windows and doors closed to help keep allergens out. Use an air purifier. Wash bedding and rugs in hot water to eliminate allergens. Wash your hair shower and change clothes after going outside to wash away pollen. Use a vacuum with a HEPA filter often. Wear a mask when you mow your lawn. Use a xylitol neti pot rinse to moisturize sinuses and keep mucus loose. Avoid outdoors whenever pollen count and smog levels are high. Check the pollen count before you go out. Wear oversized sunglasses and a hat to prevent pollen from getting on your face and into eyes. Drink plenty of water to stay hydrated in the heat. Get rid of any moisture or dampness such as repairing leaks and using dehumidifiers for mold. For a full list of references visit Ryan Hogan USN Vet Hospital Corpsman has training in the medical laboratory field orthopedics and obstetrics. His primary role now is in health education in the prevention field in Salt Lake City UT. WWW.VITAMINRETAILER.COM MAY 2015 56 VITAMIN RETAILER HEALTHANDNUTRITION Weight Loss The Myth of Effortless Supplements can help but lifestyle changes are mandatory. By Cheryl Myers he dietary supplement industry is crowded with wonder products that guarantee you ll lose 20 pounds in 20 days or your money back. The only wonder part of the product is often wondering where your money went when the product doesn t deliver on its promise. However that is not to say that there are no supplements that can be useful in weight loss and healthy weight maintenance. There are clinically studied ingredients that may make weightloss efforts more successful but they can never compensate for the need to eat a clean healthy diet and increase physical activity. It may surprise you that 20 percent of all meals are eaten in the car and Americans spend more time watching cooking on TV than actually cooking their own meals. In 1992 no state had an obesity rate above 15 percent but just 20 years later in 2012 two out of three states have an obesity rate higher than 25 percent. Much of this can be traced to problems with our food and food choices. Eating a clean healthy diet is not just about counting calories. Many recent studies have shown that food additives preservatives and trace amounts of hor- T mone-disrupting pesticides and herbicides have played a significant role in the epidemic of obesity. Whether it is high fructose corn syrup s (HFCS) altered metabolism increasing fat or aspartame and sucralose sweeteners actually increasing abdominal obesity it is clear that the first step in having a healthier weight is to walk away from Frankenfoods and toward the organic produce aisle. This cannot be a temporary change but a commitment to cleaner eating and an ongoing investment of time and money in quality foods. The list of supplements discussed here to aid weight loss is not in any way all inclusive and there are other natural product avenues that have some level of clinical validation. However here are a few examples of products with current or past popularity in health food retail Iodine Iodine is an essential mineral much in the news regarding the most optimal amount needed for brain function fatigue and cancer prevention. It is the most crucial element for thyroid function. The thyroid gland manufactures thyroid hormone using the amino acid L-tyrosine and the mineral iodine. The thyroid gland sets the rate at which the body burns fuel. It has been likened to a gas pedal in the car and a thermostat in the house. The fuel it burns are calories so higher thyroid function burns more calories even at rest and reduces the likelihood they will become stored energy also known as fat cells. Low thyroid function slows the rate of calorie burning and is associated with weight gain. America is in an iodine crisis as status of iodine has dropped as much as 50 percent in the last few decades while exposure to iodine s competitors (most notably bromide fluoride and chlorine) has greatly increased. Cancer of the thyroid gland has increased 300 percent in the last 30 years and the No. 1 prescribed drug of 2014 in the U.S. was levothyroxine (Synthroid) for hypothyroidism or low thyroid function. Interestingly obesity has shot up to record levels over this same time period. While there is no simple reason for our current obesity epidemic the increasing dysfunction of the thyroid gland could certainly be playing an important role. In one study examining the iodine levels of obese vs. non-obese women it was found that obese women had on VITAMIN RETAILER 57 MAY 2015 WWW.VITAMINRETAILER.COM HEALTHANDNUTRITION average about 45 percent lower iodine status than women without obesity. That means their circulating iodine was just a little more than half the non-obese subjects--a very significant finding. Therefore many integrative practitioners first step in helping individuals develop a healthy weight-loss or weight-maintenance program includes an evaluation of thyroid function that is far more in depth that the TSH levels currently in mainstream medical practice and a trial of therapeutic iodine. Dosage levels vary but many practitioners consider somewhere between 12.5 mg and 30 mg per day a good starting level that can be adjusted up or down as needed. There is also debate on the best form of iodine. Products with blends of iodine are useful with potassium iodide molecular iodine and sodium iodine combinations popular as each form functions slightly differently in the body. dose concentrated extract bypasses stomach acid exposure which can negate phaseolamin s activity and high dosages are not needed. Lower dosages result in reduced or eliminated gas bloating and or flatus. are natural their nutritional composition and gelling ability can vary. One of the challenges with using brown seaweed is the question of whether it will form a gel. Gel formation can be influenced by several factors including stomach pH mineral content in the stomach guluronic acid concentration in the seaweed species hydration status and delivery system of the alginate. According to researchers the more viscous a gel the greater its ability to control appetite. Another form of soluble fiber used for weight loss is derived from the konjac root which is rich in glucomannan. It too swells when exposed to fluids increases satiety and slows intestinal absorption of sugar. Though these soluble fibers can be useful these fibers may be contraindicated in individuals with esophageal strictures or other problems with the esophagus or throat. Because they are so good at absorbing fluids and quickly increasing in size and mass which in very rare cases can become lodged in esophagus. In The Complete Guide to Herbal Medicine authors Charles W. Fetrow and Juan R. Avila cite rare cases in which such blockages had to be surgically removed. However as stated this is extremely rare and should not be a risk for most healthy individuals. Soluble Fiber Fiber has been incorporated into many diet plans for numerous reasons. Foods high in fiber often involve more chewing and subsequently more time for your brain to relay the I m full signal to your stomach. Foods high in fiber also help create a feeling of satiety. White Kidney Bean Extract On average 52 percent of calories consumed by adults are carbohydrates and 55 percent of the caloric consumption of those under the age of 19. There are two types of carbohydrates simple and complex. Sugar is a simple carbohydrate in that it does not need to be broken down to be absorbed. Pasta bread bagels potatoes crackers chips popcorn rice pita oats and many more foods are complex carbohydrates meaning the digestion process must first convert them to simple sugars prior to absorption. A compound called phaseolamin is found in white kidney bean and can combat this conversion. It partially blocks the activity of alpha amylase and since the complex carbohydrate is not converted it is excreted reducing calorie absorption. Multiple studies have shown effectiveness. In one 12-week study the white kidney bean (Phase 2 Carb Controller) group lost seven pounds and the placebo group gained a pound. More than 10 clinical studies show that use of white kidney bean extract for people who regularly consume carbohydrates can assist in weight loss. In clinical trials dosages were 1000--1500 mg daily. Some individuals experience gas bloating and flatus at this dosage level. A novel innovation is a highly purified and concentrated enteric coated white kidney bean with a dosage requirement of only 2 to 4 mg per meal. Using low 58 VITAMIN RETAILER On average 52 percent of calories consumed by adults are carbohydrates and 55 percent of the caloric consumption of those under the age of 19. Fiber comes in two forms soluble and insoluble. Many fruits and vegetables contain both types of fiber. Insoluble fiber does not dissolve and helps keep food and waste flowing freely through the GI tract. The soluble fiber easily dissolves in water. When soluble fibers come into contact with water they form a gelatinous substance. One of the most interesting sources of insoluble fiber is brown seaweed. Soluble fibers from brown seaweed called alginates are used to construct the plant s cell walls. When mixed with water these alginates create a gel and can help control appetite. In studies using brown seaweed researchers found that it helps delay gastric emptying and nutrient absorption in the intestines. Alginates also help to increase the viscosity of digestive contents. Not only does this help to create a feeling of fullness but also helps modulate glucose levels. The more viscous the digestive contents the slower the rate of glucose absorption in the intestines. This is very helpful in controlling blood sugar levels which in turn can trigger appetite. Because the brown seaweed species Green Coffee Bean Extract Researchers have identified a family of chlorogenic acids and other polyphenols in the green (unroasted) coffee bean that play a role in weight loss. Roasting destroys up to 70 percent of these beneficial compounds. A Brazilian study reported in the Journal of Nutrition showed that these compounds are easily absorbed by the body. When it is standardized to contain 40 to 50 percent chlorogenic acid it facilitates calorie burning and lean body mass. The results of another human study published in the journal Phytotherapie it was found that participants using the extract lost almost twice as much of their initial weight compared to the placebo group. Researchers believe chlorogenic acid from green coffee bean inhibits the action of glucose-6-phosphatase an enzyme that releases glucose into the bloodstream for the body to use as energy. So green coffee bean extract may help the body burn fat and limits the amount of sugar released into the (Continued on page 66) WWW.VITAMINRETAILER.COM MAY 2015 Go to pharmachem for info about this advertiser HEALTHYSHOPPER Peppermint Power B Y S H A R I B A R B A N E L Retailers Healthy Shopper has been designed to help you educate customers about dietary supplements. Attach your store s business card here and photocopy for your customers. I Healthy Shopper is reprinted with permission from Vitamin Retailer magazine and is provided for educational purposes only by your local retailer. No part of this article is intended as medical advice. Always consult your health care provider for any medical problems. 60 VITAMIN RETAILER WWW.VITAMINRETAILER.COM MAY 2015 Answers 1.) b 2.) c 3.) d 4.) b 5.) a ndigenous to Europe and the Middle East peppermint (Mentha piperita) is now cultivated throughout the world. Peppermint is a hybrid mint which is a cross between spearmint and watermint. A flowering perennial peppermint usually grows between 12 and 35 inches in height and it grows best in damp shaded locations. Botanist Carl Linnaeus was the first to describe peppermint in 1753 from specimens that he collected in England. At the time Linnaeus labeled peppermint as its own species but today the consensus is that peppermint is indeed a hybrid. Cultivation and oil production of peppermint began in the United States in the 1790s and was a major export business by the mid 1800s. The U.S. is still the world s leading producer of peppermint oil making an average of 4 117 tons annually. According to Natural Medicines (formerly Natural Standard) peppermint is used in a number of ways. In beverages it is used as a flavoring agent and it is also utilized as a fragrance component in soaps and cosmetics. Topically peppermint oil is used for headache myalgias neuralgias toothache oral mucosa inflammation rheumatic conditions pruritus urticaria bacterial and viral infections as an antispasmodic in barium enemas and for repelling mosquitoes. Orally peppermint is used for the common cold cough inflammation of the mouth and pharynx sinusitis fever liver and gallbladder complaints irritable bowel syndrome (IBS) cramps of the upper gastrointestinal (GI) tract and bile ducts spasm associated with endoscopy procedures dyspepsia fever flatulence and for tension headache. It is also used for nausea vomiting morning sickness respiratory infections dysmenorrhea diarrhea and small intestinal bacterial overgrowth and as a stimulant Test Your Knowledge of Collagen Natural Medicines 1.) Peppermint is a hybrid mint of which two plants noted. a.) Spearmint & wintermint b.) Spearmint & watermint A number of studies have found that c.) Watermint & wintermint d.) None of the above peppermint is beneficial in various deliv- 2.) Peppermint usually grows between ______ and ______ in height. ery formats such as a.) 12 and 35 g b.) 12 and 35 cm peppermint tea and c.) 12 and 35 in d.) 12 and 35 ft peppermint oil. According to a 2006 3.) Peppermint is used for which of the following review of the potena.) For the common cold b.) A flavoring agent tial health benefits c.) In cosmetics d.) All of the above of peppermint tea that was published 4.) According to a 2006 review published in the journal in the journal Phytotherapy Research of the potential health benefits of pepperPhytotherapy mint tea found that in-vivo peppermint is antimicrobial and antiviResearch it was disral holds strong antioxidant and antitumor actions and some covered that in vitro antiallergenic potential. peppermint is a.) True b.) False antimicrobial and antiviral holds 5.) University of Adelaid researchers discovered that peppermint strong antioxidant acts through a specific anti-pain channel called ______. and antitumor actions and some a.) TRPM8 b.) TRPN8 antiallergenic poten- c.) TRPF8 d.) None of the above tial. In another study published in 2008 in the British Medical Journal researchers ble bowel syndrome. found that that peppermint oil was While it is generally safe to use pepmore effective than a placebo in the permint some people may be sensitreatment of IBS. tive or allergic to peppermint oil when A 2011 study conducted by it makes contact with the skin. University of Adelaid (Australia) and According to skin published in the journal Pain reactions can include anything from researchers at the university s Nervemild itching and redness to a more Gut Research Laboratory discovered extreme reaction. Natural Medicines how peppermint activates an antialso recommends that those with a pain channel in the colon soothing stomach condition in which the stominflammatory pain in the GI tract. Our ach does not producing hydrochloric research shows that peppermint acts acid should not use enteric-coated through a specific anti-pain channel peppermint oil because the enteric called TRPM8 to reduce pain sensing coating may dissolve too early in the fibers particularly those activated by digestive process. mustard and chili said Dr. Stuart Brierley. This is potentially the first References step in determining a new type of mainstream clinical treatment for irrita- PRODUCTSPOTLIGHT Yummy Gummy Multis BY CRISTINA GOODWIN ry giving a child an off-tasting supplement and a parent will likely be faced with resistance possibly even kicking and screaming. There s also the child who may pretend to swallow the pill only to hide it under the furniture. To help ease the stress of both child and parent alike manufacturers are perfecting gummy alternatives to kid s supplements and multivitamins. Keep in mind the parent has to make sure the child doesn t mistake the gummy for candy to ensure proper dosage. Below are a handful of kid s gummy multivitamins that will make them want to take their vitamins. T Jungle Whole Food Texas-based Bluebonnet Nutrition offers Super Earth Rainforest Animalz Whole Food Based Multiples. The supplement is free of gluten dairy fillers and artificial colors or sweeteners. The natural fruit flavors are so yummy kids will never know that Super Earth Rainforest Animalz are sweetened with EarthSweet an all-natural sweetening mix of juice concentrates and are available in both assorted and single natural fruit flavors (cherry grape or orange). The suggested retail price is 17.95 for 90-ct. bottle and 32.95 for a 180-ct. bottle. For more information call (281) 240-3332 or visit Kids Code Garden of Life LLC (Palm Beach Gardens FL) offers Vitamin Code Kids a great-tasting chewable whole-food multivitamin to support children s healthy development. Made with its patented Vitamin Code vitamins and minerals in a base of 24 family-farmed organic fruits and vegetables Vitamin Code Kids supports the active growing child. Clean whole-food ingredients are gently blended never heated into a base of organically grown fruits and vegetables--and there are no artificial flavors sweeteners or additives. The cherry berry chewable bears contain only 1 g of sugar plus live probiotics (1 billion CFU) for healthy digestion and immune system support. Vitamin Code Kids is Non-GMO Project Verified and verified kosher gluten free and dairy free. Vitamin Code Kids delivers everything a parent wants in kid s multivitamins--and nothing they don t want (MSRP 17.25 30-ct. 29.15 60-ct.). For more information call (561) 748-2477 or visit Baby D3 The American Academy of Pediatrics recommends that breast-fed or partially breast-fed infants receive 400 IUs of supplemental vitamin D daily. California-based Nordic Naturals Baby s Vitamin D3 (MSRP 14.95) is in the natural form of vitamin D (cholecalciferol) for optimal absorption. It offers the recommended dosage in just one drop. The product has a convenient applicator for use when breast-feeding or in food and beverages. Baby s Vitamin D3 contains no coloring or flavoring in order to ensure that babies get only the purest high-quality vitamin D nutrition. For more information call (800) 662-2544 or visit Gummy Bears Rainbow Light Nutritional Systems (Santa Cruz CA) Gummy Bear Essentials Multivitamin & Minerals delivers essential nutrients needed to nourish the minds and bodies of active growing kids. The vitamins are 100 percent natural contain no artificial colors flavors sweeteners preservatives or additives and are offered in single-serve packets for easy grab and go. The strawberry lemon or orange flavored gummy bears are free of gluten lactose dairy yeast nuts and hydrogenated oils. Each box contains 30 packets and is made from 100 percent recycled paperboard (MSRP 15.49 30-ct. box). For more information call (866) 972-6879 or visit U-Cube There s a lot to love about U-Cubes Children s Multi-Vitamin & Mineral Gummies ( 11.98 60-ct. 19.98 120-ct.) by Solgar Vitamin and Herb (Leonia NJ). They are non-GMO and free of beef pork gelatin artificial colors or flavors gluten wheat and dairy. Each serving of these tapioca and pectin-based gummies provides 100 percent DV (400 IU) of vitamin D3 for children 4 years and older and 50 percent DV (200 IU) for children aged 2 to 3. In addition U-Cubes are made in small batches that ensure the highest quality and are rigorously tested for safety and potency. For more information call (800) 645-2246 or visit MAY 2015 WWW.VITAMINRETAILER.COM The Green Gummy Yum-Yum PS100 Gummies created by Jarrow Formulas (Los Angeles CA) helps support brain function in growing kids. The gummies are formulated with Enzymotec s new ingredient Sharp-PS Green which provides 100 mg of phosphatidylserine (PS) an essential nutrient in the cell membrane for healthy cognition mental performance attentiveness and reaction time. The product is also soy free non-GMO and eco-friendly. The strawberry flavored gummy supplement provides the right amount of vitamins and minerals to help shape the child s brain and its development (MSRP 27.95 60 gummies). The suggested dose is one gummy twice a day. For more information call (310) 204-6936 or visit VITAMIN RETAILER 61 SUPPLEMENTSCIENCE Garcinia Cambogia More Than Weight Loss By Gene Bruno MS MHS Chief Academic Officer Huntington College of Health Sciences ast year I wrote an article on Garcinia cambogia for Vitamin Retailer. In that article I focused on the weight loss-related benefits of this nutraceutical. In this article I will share other research that demonstrates Garcinia cambogia s value in lowering triglycerides increasing glycogen production and preferentially promoting the use of fat as a fuel source during exercise in favor of carbohydrates. L points or about 17 percent. This reduction was significantly lower than that experienced by the control group (p 0.04). Increasing Glycogen Production This study4 examined the effects of HCA supplementation on glycogen production after a meal in eight healthy exercising male volunteers (average age of 22 years). The volunteers completed a 60-minute cycling exercise and received 500 mg HCA or placebo. Then seven days later the same experiment was performed but those who had previously received the HCA now received the placebo and vice-versa. In either case to also ate a high-carbohydrate meal (2 g carbohydrate kg body weight 80 percent carbohydrate 8 percent fat 12 percent protein). Muscle biopsy samples were obtained from the Vastus lateralis (a muscle in the thigh) immediately and three hours after the exercise. The results showed that HCA supplementation significantly lowered the insulin response to the meal. Furthermore glycogen production was increased significantly with HCA compared to placebo (see graph Increase in glycogen production ). Also HCA supplementation significantly increased the use of fat as an energy fuel. It should also be noted that the decreased use of carbohydrates as a fuel discussed in the following studies is an indication of glycogen sparing. Background The Garcinia genus consists of 180 species distributed in tropical regions of Asia Africa and Polynesia.1 A few of these species including G. cambogia (also known as Malabar tamarind) contain (-)-hydroxycitric acid (HCA) which has some interesting biological properties.2 The effects of HCA will be the focus of this article. Fat Utilization During Exercise and Increased Time To Exhaustion This study5 investigated the effects of short-term HCA ingestion on endurance exercise performance and fat metabolism in untrained women. Six subjects received 250 mg of HCA or placebo for five days and then participated in cycle ergometer exercise. At a later date the same experiment was performed but those who had previously received the HCA now received the placebo and vice-versa. The results showed that HCA tended to decrease the amount of carbohydrate burned as fuel during one hour of exercise while increasing the amount of fat burned as fuel. In addition subjects using HCA were able to exercise for a longer period of time before reaching exhaustion (p 0.05 see graphs Exercise time to exhaustion). An earlier study6 in men found similar results. Six untrained men received 500 mg HCA or a placebo for five days and then did moderate intensity exercise. Two days later the same experiment was performed but those who had previously received the HCA now received the placebo and vice-versa. The results WWW.VITAMINRETAILER.COM MAY 2015 Lowering triglycerides In 2014 a 60-day study3 analyzed the effect of G. cambogia on the triglycerides (blood fats) in obese women (age 25-60 years). The women divided in treated (n 30) and control (n 13) groups. Those in the treated group received 2 400 mg (800 mg 3 times day) of garcinia extract (50 percent of HCA) and those in the control group received a placebo. Subjects in both groups were also given dietary guidance to reduce their daily caloric intake by 380 calories day. The results showed that triglyceride levels in the treated group were reduced from 132.35 41.61 mg dL to 109.52 38.7 mg dL. That s a decrease of 22.83 62 VITAMIN RETAILER were that blood concentrations of free fatty acids were significantly increased and the use of carbohydrates as a burned fuel decreased with HCA ingestion demonstrating that short-term HCA ingestion increases fat oxidation in untrained men. Likewise a similar study7 was conducted in athletes who received 250 mg of HCA or placebo for five days and then performed cycle ergometer exercise until exhaustion. At least two days later the same experiment was performed but those who had previously received the HCA now received the placebo and vice-versa. The results showed that HCA increased the amount of fat burned as a fuel while significantly decreasing the amount of carbohydrate burned as a fuel during exercise (p 0.05). This also led to an increase in the amount of time subjects could exercise until exhaustion (p 0.05). The authors noted that shortterm administration of HCA not only enhanced endurance performance and improved fat burning but also spared glycogen utilization during moderate intensity exercise in athletes. and its active compound HCA have been shown to have efficacy as part of a program to promote weight loss. In addition other research has demonstrated that HCA has value as an ergogenic aid during exercise. Specifically it has been shown to increase glycogen production and preferentially promote the use of fat as a fuel source during exercise in favor of carbohydrates. Also HCA was shown to help lowering triglycerides. VR For a full list of references visit Gene Bruno MS MHS the dean of academics for Huntington College of Health Sciences is a nutritionist herbalist writer and educator. For more than 30 years he has educated and trained natural product retailers and health care professionals has researched and formulated natural products for dozens of dietary supplement companies and has written articles on nutrition herbal medicine nutraceuticals and integrative health issues for trade consumer magazines and peer-reviewed publications. Conclusion Previously Garcinia cambogia RETAILFUNDAMENTALS (Continued from page 28) Be Bright Be Brief Be Gone Cut to the chase. If the purpose of your message is to give information ... don t fluff it up This creates extra words people don t have time to read. You may only have seconds to make a connection and engage your audience. One of the reasons Twitter has become such a great business tool is because their model is just that Be Bright Be Brief Be Gone (I didn t coin that phrase David Currier and Jay Frost did but I encourage you to incorporate it to help you stay on track). TIP To create keywords take a few minutes and write down as many two- or three-word groupings that describe your niche area or expertise. Chances are you will come up with a few keywords that will get you started. TIP Add keywords to titles headings content images and page URLs. Include a Call-to-Action. Have a plan when preparing your messages. What do you want followers to do Do you want them to click through to learn more about you read a brochure or article discover a great offer or attend a function TIP Brainstorm first and build out your message from there. Create a plan and be sure to include a link to land followers exactly where you d like them to go. Google Alerts https alerts Consider This I strongly encourage retailers to include the following social platforms in their marketing plans as a base LinkedIn company page and Twitter. LinkedIn s company page supports your business connections where Twitter focuses on your customers. They re both simple ways to share that your business is worth following and a great place to create call to actions. There are tons of platforms with special values worth investigating so I encourage you to take the time to make a plan--step back and look at the big picture of what you wish to accomplish and share what actions you want your followers to take ... then jump in and enjoy VR Be Searchable--Create Keywords Knowing your business and area of expertise is vital. The social media next step or goal is to master delivering your message using a few keywords that people will use to search for you and your content. Think about what niche you have and let the keywords fall into place. By integrating well thought out and consistent keywords you have a much better chance of increasing your search engine ranking (moving you up on the list) and being found. MAY 2015 WWW.VITAMINRETAILER.COM Gathering Content One barrier that retailers face is time for gathering social media content. People who enjoy spending time online like to click on links to learn more. I ve discovered a few resources that make content gathering a breeze. My favorites are Alltop http Feedly http Debby Swoboda Mayhew is founder of and an industry consultant since 1988. VITAMIN RETAILER 63 NATURALMEDICINE with Dr. Michael Murray The Rising Epidemic of B Y M I C H A E L T. M U R R A Y N D Gout minimum. Simple sugars (refined sugar honey maple syrup corn syrup fructose etc.) increase uric acid production while saturated fats decrease uric acid excretion. The diet should focus on complex carbohydrates such as legumes whole grains and vegetables rather than on simple sugars. Liberal fluid intake keeps the urine diluted and promotes the excretion of uric acid. Furthermore dilution of the urine reduces the risk of kidney stones. Drink at least 48 ounces of water each day. M ore than likely you are familiar with gout an inflammatory arthritis triggered by crystallization of uric acid within the joints. It causes severe pain and swelling. Gout has reached epidemic proportions in the Unites States as it now affects about 10 million people--or about 5 percent of the adult population. In addition elevations in blood uric acid levels are found in over 43.3 million (21 percent) adults in the U.S. With gout affecting so many Americans it is important for retailers to understand what it is and what natural approaches may be helpful in preventing gout attacks. Cherries to the Rescue One of the old folk remedies for preventing gout attacks is the consumption of cherries. There is a growing body of science to support this recommendation. For example consuming one-half pound of fresh or canned cherries daily has been shown to (Continued on page 67) Drug Use in the Treatment of Gout and Natural Alternatives The medical treatment of acute gout is administration of colchicine the antiinflammatory drug originally isolated from the plant Colchicum autumnale (autumn crocus meadow saffron). Colchicine has no effect on uric acid levels rather it stops the inflammatory process by basically poisoning white blood cells and preventing their movement into areas of inflammation. More than 75 percent of patients with gout show major improvement in symptoms within the first 12 hours after receiving colchicine. However up to 80 percent of patients are unable to tolerate an optimal dose because of gastrointestinal side effects which may precede or coincide with clinical improvement. Colchicine may also cause bone marrow depression hair loss liver damage depression seizures respiratory depression and even death. Other anti-inflammatory agents are also used in acute gout including various nonsteroidal anti-inflammatory drugs (NSAIDs) such as indomethacin phenylbutazone naproxen and fenoprofen. Once the acute episode has resolved drugs like allopurinol or febuxostat (Uloric) to keep uric acid levels within a normal range. These drugs are also associated with side effects and do not address the underlying cause. In the acute attack colchicine may be necessary to prevent excessive joint destruction. Taking a natural anti-inflammatory at the first instance of a flare up may be able to arrest the need for colchicine. Here are a couple of options Curcumin the yellow pigment of turmeric (Curcuma longa) exerts significant anti-inflammatory effects. However regular curcumin powder is poorly absorbed. Forms of curcumin shown to possess better absorption such as Meriva and Theracurmin are recommended for best results. Follow dosage recommendations on product labels. Celadrin is an all-natural matrix of special cetylated esterifed fatty acids that reduce inflammation. The unique features of Celadrin as a natural product include an ability to reduce inflammation and pain quickly with no side effects as demonstrated in clinical trials published in the internationally acclaimed Journal of Rheumatology. Available in cream and capsule form Celadrin is clinically proven to produce results. Celadrin cream can be applied to affected areas on an as needed basis. Orally the dosage is 1 000 mg per day. WWW.VITAMINRETAILER.COM MAY 2015 What Causes Gout Gout is the result of either increased synthesis of uric acid reduced ability to excrete uric acid or both over production and under excretion of uric acid. Several dietary factors are known to be trigger gout including consumption of alcohol high-purine-content foods (organ meats meat yeast poultry etc.) fats refined carbohydrates and excessive calories. Here s a closer look Alcohol increases uric acid production by accelerating purine breakdown. It also reduces uric acid excretion by increasing lactate production which impairs kidney function. Elimination of alcohol is all that is needed to reduce uric acid levels and prevent gouty arthritis in many individuals. A low-purine diet has long been the mainstay of dietary therapy for gout. Foods with high purine levels should be entirely omitted. These include organ meats meats shellfish yeast (brewer s and baker s) herring sardines mackerel and anchovies. Intake of foods with moderate levels of protein should be reduced as well. These include dried legumes spinach asparagus fish poultry and mushrooms. Refined carbohydrates fructose and saturated fat intake should be kept to a 64 VITAMIN RETAILER NEWPRODUCTS VR s New Products section is a FREE service to industry members. Send new product press releases and photos to Daniel Breeman Vitamin Retailer 431 Cranbury Road Ste. C East Brunswick NJ 08816 or email to DanielB Spiced Soap MIDDLEBURY VT--Vermont Soap has released Spicewood Extra-Strength Organic Deodorant. The company launched Sage Lime Organic Deodorant last year and because of the positive reviews added another fresh-scented deodorant. Spicewood is a naturally fragrant extra-strength and extra long-lasting deodorant stick that is certified to organic food standards and free of propylene glycol triclosan or artificial colors or fragrances. Plus it is non-GMO and gluten free (MSRP 9.98 3.25-oz.). It is a bacteria-fighting alternative for consumers with sensitive skin and reactive bodies of all skin types and is formulated with coconut oil cornstarch spicewood essential oil blend beeswax and rosemary extract. For more information call (866) 762-7482 or visit LipDrink Lip Balm GREAT BARRINGTON MA-- Recommended by The Skin Cancer Foundation LipDrink Lip Balm with SPF 15 by jane iredale leaves lips soft smooth and beautifully protected (MSRP 15). It s formulated to protect lips from the damaging effects of UV rays while moisturizing and hydrating. The lemon-scented lip balm combines a variety of waxes and oils to provide a protective shield and blends together antioxidants green tea extract and vitamins E and C to help prevent future damage. The protective drink for your lips is available in three shades with two new tinted shades that provide a hint of color including Crush a sheer berry and Buff a shear nude as well as their original Sheer which is translucent. For more information call (800) 762-1132 or visit The Hammam AMSTERDAM THE NETHERLANDS--RITUALS has released Hammam Body Mud a purifying body scrub. The Hammam which means spreader of warmth is one of the oldest cleansing traditions in the world originating in Turkey and helps to purify both soul and body to promote inner and outer harmony and balance. Enjoy Hammam Body Mud with mineral-rich rhassoul clay and refreshing eucalyptus made to nourish and revitalize the skin. The natural micro-scrub leaves the skin feeling fresh and soft while the eucalyptus provides a soothing and calming effect (MSRP 17 for 5-fl oz.). For more information call (800) 748-4838 or visit Kids Omega Boost WATSONVILLE CA--Part of the Omega Boost family Omega Boost Junior from Nordic Naturals is a tasty creamy alternative to deliver essential omega-3s to kids. Omega-3 is important for kids optimal health and development. Available in Paradise Punch flavor the smooth liquidlike formula supports the brain and eyes as well as a healthy immune and nervous system in children two-years-old and under. Only a half-teaspoon gives kids 285 mg of omega-3s. With Nordic Naturals fast absorption Omega Boost Junior is free of gluten corn dairy yeast GMOs and artificial colors or flavors (MSRP 19.95 6-fl-oz.). For more information call (831) 724-6200 ext. 3 or visit KannaKick SAN DIEGO CA-- Kannaway LLC offers consumers a functional food chew that contains CBD-Rich Hemp Oil. As soft as taffy KannaKick provides natural energy B vitamins and 5 mg of hemp-based CBD and 100 mg of caffeine (slightly more than one cup of coffee). Each single pack comes with four individually wrapped chews and is available in five different flavors Sour Apple Icy Mint Chocolate Fudge Orange Mango and Cinnamon Fire. The chews not only taste great but also deliver optimal energy lasting up to three hours (MSRP 31.98 2-pack). For more information call (800) 407-5929 or visit Flo Rida Fusion BOCA RATON FL--Celsius Holdings Inc. and hip-hop superstar Flo Rida have announced the launch of an onthe-go version of the Flo Fusion Powder. Flo Fusion Transformation Accelerator On-the-Go Powder is backed by six published university studies and is clinically proven to burn at least 100 calories per serving burn up to 93 percent more body fat per serving increase the body s metabolism and provide lasting energy. Celsius Flo Fusion is available in Berry or Orange flavor and is free of sugar high fructose corn syrup aspartame preservatives and artificial colors or flavors. Contact the company for pricing. For more information call (866) 423-5748 or visit No Joke Deodorant TENAFLY NJ--Hlavin s Lavilin 72 Hour Roll-on Deodorant all-around winner of New York Magazine s aluminum-free deodorant competition is free of aluminum alcohol and parabens. It eliminates perspiration odor for up to 72 hours with one application. A proprietary combination of natural herbs neutralizes perspiration odor at the source. Lavilin eliminates the bacteria that causes body odor without using harsh chemicals or clogging pores (MSRP 16). For more information call (201) 387-0200 or visit MAY 2015 WWW.VITAMINRETAILER.COM VITAMIN RETAILER 65 NEWPRODUCTS Reg Activ FARMERS BRANCH TX--Essential Formulas Inc. (EFI) announced the U.S. inaugural debut of its three Reg Activ formulations containing the glutathione-boosting probiotic Lactobacillus fermentum ME-3 which help boost glutathione levels and generate powerful antioxidant support for the cardiovascular system and condition-specific ingredients for synergistic health-promoting benefits. Reg Activ Cardio Wellness ( 55.55) includes essential B vitamins and CoQ10 (ubiquinol) Reg Activ Detox & Liver Health ( 50.80) blends together proven ingredients to support healthy glutathione levels and promote healthy detoxification and normal liver function and Reg Activ Immune & Vitality ( 50.80) provides consumers with a revolutionary probiotic blend of ME-3 plus KP08 that supports immune system health and provides a core energy boost. For more information call (972) 255-3918 or visit These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose treat cure or prevent any disease. Diabetic Pain Relief NORFOLK VA--Created by diabetes researcher Dr. Aaron Vinik NutriNerve supplements are specifically developed to reduce the severity of neuropathic pain by addressing chemical imbalances head on with the use of the new formula introducing vitamin B-12 and vitamin D. It also includes alpha lipoic acid to improve diabetic neuropathy symptoms benfotiamine (vitamin B-1) to significantly improve neuropathy scores gamma-linolenic acid (GLA derived from borage oil) which has been shown to restore nerve conduction velocity and vitamin C for powerful antioxidant properties. The newly added vitamin B-12 restores blood flow producing myelin synthesis a fatty substance that protects the nerve fibers and vitamin D to specifically address the vitamin deficiency common to type 1 and 2 diabetes. (MSRP 99.95 60-day supply). For more information call (800) 344-9993 or visit SPF 15 Brightening Moisturizer DENVER CO--Mineral Fusion has introduced its new SPF 15 Brightening Moisturizer ( 24.99). The lightweight hydrating moisturizer brightens skin while providing sun protection and is formulated with vitamin C and orange oil to naturally brighten and even out skin tone as well as coconut oil for lightweight nourishment that penetrates deep into skin for long-lasting hydration. The broad spectrum all-natural moisturizer is free of gluten parabens artificial colors talc and fragrance. In addition it is hypo-allergenic never tested on animals and 100 percent vegan. For more information (800) 428-1668 or visit HEALTHANDNUTRITION (Continued from page 58) bloodstream. Because blood sugar levels aren t rapidly rising and falling the theory is that one experiences fewer cravings while burning calories at the same time. However there are several types of chlorogenic acids in green coffee bean and they occur in a natural ratio. One problem with supplements are that individuals may be selling a single chorlogenic acid that is not a full spectrum green coffee bean extract so the research results cannot be extrapolated to products such as this. After it exploded in popularity a few years ago there has been unfortunate confusion and even duplicity surrounding green coffee bean research. In one of the more well-known cases a popularly endorsed extract didn t live up to its claims when it was disclosed that the research results had been falsified. There have been reports of coffee byproducts (i.e. roasted coffee bean dust) in a capsule that contain little or 66 VITAMIN RETAILER no chlorogenic acid. ConsumerLabs reported that Green coffee bean extract (GCBE) supplements may help you lose weight. But found that 50 percent of the supplements it recently selected for testing didn t contain expected amounts of key chlorogenic acids -- compounds associated with the extract s weight-loss effects. Out of the eight green coffee bean extract supplements selected one contained no extract and three others contained only 6 percent 29 percent and 82 percent of expected amounts based on chemical analyses repeated in two independent laboratories. Sometimes the popularity of a product can lead to its demise as ineffective versions enter the market (especially in mass market) and diminish its reputation but according to studies natural standardized (authentic) green coffee bean extract may play a role in assisting with healthy weight loss. be rife with charlatans there are legitimate supplements that can prove quite useful in helping to reduce or maintain a healthy weight. Weight loss and weight maintenance is hard work and anything that can be used as a legitimate tool to aid in this effort should be valued and supported. VR For a full list of references visit Cheryl Myers is an integrative health nurse author and an expert on natural medicine. She is a nationally recognized speaker who has been interviewed by the New York Times Wall Street Journal and Prevention magazine. Her many articles have been published in such diverse journals as Aesthetic Surgery Journal and Nutrition in Complementary Care and her research on botanicals has been presented at the American College of Obstetrics and Gynecology and the North American Menopause Society. Myers is the head of Scientific Affairs and Education for EuroPharma Inc. WWW.VITAMINRETAILER.COM MAY 2015 Conclusion Although the weight-loss category may ADVERTISERINDEX ADVERTISER Ajinomoto North America Inc. Amazing Herbs Bluebonnet Nutrition Corp. Capsugel Continental Vitamin Company Dr. Willard s Essential Formulas Essential Formulas Frey Vineyards Hyalogic Life Extension Foundation Michelle s Miracle Nature s Plus Nordic Naturals North American Herb & Spice NOW Foods NOW Foods (Personal Care) Pharmachem Labs (Phase 2) Rainbow Light Nutritional Systems Redd Remedies Sanhelios Scandinavian Formulas Inc. Taiyo International Inc. Wakunaga of America Co. Ltd. Xlear Inc. PAGE 33 31 C4 16 23 37 13 29 17 15 27 34 2-3 9 C2 C3 21 59 11 7 25 39 19 1 5 PHONE (201) 292-3200 (800) 241-9138 (281) 240-3332 (888) 783-6361 (800) 421-6175 (605) 343-8100 (972) 255-3918 (972) 255-3918 (707) 485-5177 (866) 318-8484 (877) 354-6512 (800) 939-3199 (800) 645-9500 (800) 662-2544 (800) 243-5242 (888) 669-3663 (888) 669-3663 (800) 536-0609 (800) 526-0609 (888) 453-5058 (800) 641-7555 (800) 688-2276 (763) 398-3003 (949) 855-2776 (877) 599-5327 WEB ajinomoto amazingherbs bluebonnet capsugel cvc drwillards essentialformulas essentialformulas frey hyalogic lifeextension michelles naturesplus nordicnaturals nahs nowfoods nowsolutions pharmachem rainbowlight reddremedies sanhelios scandinavian taiyo wakunaga xlear NATURALMEDICINE with Dr. Michael Murray (Continued from page 64) be very effective in lowering uric acid levels preventing attacks of gout and reducing blood markers of inflammation. In the most recent study researchers found that cherry intake (defined as one-half cup or 10 to 12 cherries or the equivalent in extract form) over a two day period was associated with a 35 percent lower risk for gout attacks and that cherry extract intake was associated with a 45 percent lower risk. Cherries hawthorn berries blueberries and other dark red-blue berries are rich sources of flavonoids (plant pigments) known as anthocyanidins and proanthocyanidins. In addition to consuming these fruit as food extracts of cherry bilberry grape seed or pine bark can be used as dietary supplements to ensure sufficient intake of the beneficial compounds that help fight gout. The typical dosage recommendation for these flavonoid rich extracts is 150 to 300 mg daily. contain 85 percent 3nB and other celery phthalides has shown benefit in the treatment of rheumatism --the general term used for arthritic and muscular aches and pain. In these studies that included gout sufferers the pain had been present for approximately 10 years in a remittent or continual form and it led to a lack of joint mobility and pain that prevented the carrying out of household duties hobbies and activities involved in employment of these subjects. The results of the studies were extremely positive and quite statistically significant. The chance that such a positive effect in reducing pain in these subjects was a placebo effect was less than one in 1 000. Subjects experienced significant pain relief after three weeks of use with the average reduction in pain scores of 68 percent and some subjects experiencing complete 100 percent relief from pain. Most subjects achieved maximum benefit after six weeks of use although some did notice improvements the longer the extract was used. It appears to be particularly helpful for sufferers of gout as 3nB lowers the production of uric acid by inhibiting the enzyme xanthine oxidase. These benefits persisted even after taking into account factors that can affect gout risk such as gender obesity purine intake (in foods that can increase gout risk) plus use of alcohol diuretics and anti-gout medications. The recommended dosage for celery seed extract (85 percent 3nB and related phthalides) is 75 to 150 mg twice daily. Final Comment Obesity and its related insulin resistance are associated with a significant increased risk for gout as well as an earlier age of onset. Weight loss in overweight individuals is associated with significant improvement in blood uric acid levels and gout symptoms. Therefore safe and effective weight loss is a primary treatment goal in overweight individuals. VR Michael T. Murray ND is widely regarded as one of the world s leading authorities on natural medicine. He is a graduate former faculty member and serves on the Board of Regents of Bastyr University in Seattle WA. The author of more than 30 books on health nutrition Murray is also director of product development and education for Natural Factors Nutritional Products. For more information visit VITAMIN RETAILER 67 Celery Seed Extract The compound 3-n-butylphthalide or 3nB for short is unique to celery and is responsible for the characteristic flavor and odor of celery. A celery seed extract standardized to MAY 2015 WWW.VITAMINRETAILER.COM Back Talk Mark Menolascino MD MS ABIHM ABAARM IFMCP Phone (307) 732-1039 Email dmark Website & THIS MONTH Mark Menolascino MD MS ABIHM ABAARM IFMCP is the founder and medical director of the Meno Clinic Center for Advanced Medicine in Jackson Hole WY specializing in utilizing nutritional strategies for optimal health and performance. He is also a key medical opinion leader at LycoRed a nutraceutical ingredient supplier and combines multiple disciplines with four board certifications including internal medicine anti-aging medicine functional medicine integrative holistic medicine and a master s degree in psychoneuroimmunology. longer tell they are consuming a supplement with fish oil. testing to look for nutrient deficiencies. Question How do consumers make sense of conflicting supplement formulations Question What is your best piece of advice for consumers regarding supplement decisions Answer This is very difficult even for me sometimes when I go to the store and look at the dizzying display of lotions and potions. The claims made on some of them are ridiculous but still it can be very difficult to sort through the hype from the hope. In my clinic I stick with the six to 10 medical grade supplement companies that I trust. I have been to several of the facilities I know the owners and developers and have trust in the process. These companies figured out long ago not to compete with grocery store inferior quality but to hold their standards of genus species potency toxicity and microbiological contamination of both the raw ingredients and finished product. For example the professional grade fish oil I recommend has a patented distillation process and on the bottle is a number you can look up on the internet and see that batch gas chromatograph of the constituents so you know it is pure. This is the level that medical grade nutraceutical companies are striving for which will help consumers better understand formulations. Answer First read the other ingredients list. If there is anything you cannot pronounce then avoid it Many additive fillers and binders including dyes are known toxins but are still found in food and supplements. One of the leading grocery store multivitamins has 46 other ingredients in it as fillers dyes and binders with several know toxins. Also as Hippocrates told us Let food be thy medicine so look to healthy food first and supplements second. The problem is however that our food supplies are so nutrient depleted and our soils are nutrient depleted that it is hard to stay ahead of our stressful lives to maintain optimal support. Most clients who go through intracellular micronutrient testing are low in more than five nutrients and some are low in everything. Question When purchasing supplements how important is it that consumers understand ingredient labels Answer We have two groups of consumers--one group does extensive research looks thoroughly at labels looks for the GMP and NSF-type certification and scrutinizes the other ingredients list which is usually where the binders and fillers show up and they pick the highest quality they can find. These are also the consumers seeking out integrative functional MDs or naturopaths as they want nutrition as medicine and are looking for expertise in the field of nutraceuticals. The other group is simply looking for the cheapest price. Not actually understanding the ingredient label consumers will buy the cheapest bargain brand assuming there is no difference. For example many fish oil supplements can be rancid and oxidized upon opening and consumers would never know if it was from industrial harbor grade fish or the desired clean North Sea sardines. When I provide my clients with the professional grade I use within days they can no 68 VITAMIN RETAILER Question What can natural products retailers do to help educate their customers Answer As above I like the way companies are doing pre-clinical research on their ingredients controlling the process from seed to supplement and branding their products as certified to a high level of purity activity and quality. I would recommend companies make similar efforts and we really need to police ourselves more to discourage low-quality supplements that flood the market. Retailers should position themselves as leaders in quality provide education scrutinize ingredients and provide the highest quality possible. I also feel some level of education has room to grow as we are educating providers yet we are not doing much to educate our clients. That is why the bombardment of negative press regarding supplements sticks with most people as they have no frame of reference to sort the wheat from the chaff. WWW.VITAMINRETAILER.COM MAY 2015 Question How can consumers know which supplements are the best fit for their health needs goals Answer Short of meeting with an integrative or functional medicine physician naturopath or other health care expert in nutrition finding supplements that are the best fit is a difficult goal to achieve. The hype on the internet and television is daunting and the myriad displays at the stores are amazing and not very helpful. Most all of us benefit from a quality multivitamin with antioxidant omega-3 and vitamin D. Consumers can consult HCPs to help guide them discussing quality and usefulness of supplements or can also get Go to nowfoods for info about this advertiser Go to bluebonnet for info about this advertiser