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Description: In This Issue: Supplements' Role in Healthy Blood Sugar, Supply Innovation, Herbs & Botanicals, and EFAs

SO VIS UR IT O em CE UR ag B az OO ON ine K L .co T IN A VRM Media Publication m OD E so ur AY ce ww w. ni bo ok November December 2016 Go to sabinsa for info about this advertiser Go to nowpl for info about this advertiser TableofContents Proud Supporter of VOLUME 21 NO. 9 NOVEMBER DECEMBER2016 F E A T U R E S 28 Supplements Role in Healthy Blood Sugar Consumers are taking a proactive role to combat high blood sugar--which includes taking supplements. 31 Omega-3s Full Steam Ahead Despite overhang from iffy research conclusions and attendant mass media frenzies the industry boldly forges ahead with innovative products and new education initiatives. 28 A L S O I N S I D E 40 Supply Innovation NIE has given companies a chance to highlight their latest most innovative offerings. C O L U M N S 10 17 23 24 25 26 38 39 47 47 48 Industry News Ingredient News AHPA Update Association News Science Update SupplySide West Wrap-up Conventions & Meetings Equipment & Packaging Advertiser Index Industry Events Supplier of the Month 4 First Word 6 Condition Specific 34 Marketing Innovation 36 Functional Foods 36 FREE Subscription (Print Digital or BOTH) & E-newsletter Available Copyright 2016. Nutrition Industry Executive (ISSN 2331-2602) Volume 21 Number 9 November December 2016. Nutrition Industry Executive is published monthly (except for bimonthly January February and July August and November December) by VRM Media 431 Cranbury Road Suite C East Brunswick NJ 08816 USA Phone (732) 432-9600 Fax (732) 432-9288. All rights reserved including the right to reproduce in whole or in part. Not responsible for unsolicited material. Opinions expressed in by-lined articles or advertisements are not necessarily those of Nutrition Industry Executive or its owners. Publisher is not liable for advertiser product claims or representations. Advertisers assume total responsibility for the contents of their advertisements. Printed in U.S.A. Basic annual subscription rate is 50.00. Periodicals Postage Paid at East Brunswick NJ 08816 and additional mailing offices. POSTMASTER Send address changes to Nutrition Industry Executive P.O. Box 15026 North Hollywood CA 91615-5026. Subscription Customer Service Nutrition Industry Executive P.O. Box 15026 North Hollywood CA 91615-5026 USA Phone (818) 286-3170 Fax (800) 869-0040 niecs Back Issues & Single Copies For order information contact (732) 432-9600 or info March issue is 25.00. All other issues are 8.00 each. 2 Nutrition Industry Executive November December 2016 Go to plt for info about this advertiser FirstWord Post-election Stress Disorder t s Election Day as I write this and I think as a country no matter what our political leanings we could all agree that this was one of the most polarizing campaign seasons seen and it has taken a toll on many of us. In fact the American Psychological Association in a recent survey found that 52 percent of adults are dealing with stress and anxiety brought on by the election. We re seeing that it doesn t matter whether you re registered as a Democrat or Republican U.S. adults say they are experiencing significant stress from the current election Lynn Bufka the association s executive director for practice research and policy said in a news release. ... Election stress becomes exacerbated by arguments stories images and video on social media that can heighten concern and frustration particularly with thousands of comments that can range from factual to hostile or even inflammatory. Not to cause you more stress but with the votes counted we can move on to the holiday season. I mention this to help put the focus on our own our customers and our consumers overall wellbeing. Working on this month s feature article on blood sugar health I noticed that the participants pointed out how stress impacts our health--including exacerbating diabetes-- and how the natural products industry has a responsibility to the health of others. Mitch Skop senior director of new product development with Pharmachem Laboratories in Kearny NJ said when watching TV the repetitive commercials for pharmaceuticals that control type 2 diabetes is a giveaway that this category is a perennial concern where millions of Americans are seeking support. But it s a sensitive category for us in the natural products business. Even though some of I our products have positive effects on serum glucose and insulin it s imperative that we do not address a disease state. Our products though effective are for long-term lifestyle health and wellness and while they may be effective in slowing the onset of certain disease states claims language--and consumer acceptance--are hard to come by. I suppose they should be. As for handling our own stress last year for VRM Media s flagship publication Vitamin Retailer magazine I interviewed herbalist and botanist Dr. Christopher Hobbs and asked him how to deal with stress. I believe his advice bears repeating Internally generated stress or relationship stress what one might call personal stress can be the worst and most damaging because it can be unrelenting. The primary stress-relieving healthy habits Deep and refreshing sleep. Getting to bed early and good sleep hygiene can heal much. Aerobic exercise daily. Walk more sit less. Eat simple whole food and some raw foods. As much as possible avoid refined sugar in any food or drink keep moderate stimulant use like tea and coffee to the morning hours only. Stretching walking meditation time in nature wild spots. Vacations. Just remember On vacations we don t work Equanimity. A feeling that all is well all is ok all is as it should be. We are not in control anyway so it s best to just go with the flow. That doesn t mean we are helpless and take no responsibility in our lives. Now is a good time to take a little better care of ourselves. The staff of VRM Media would like to wish our readers a very non-partisan stress-free happy and healthy holiday season. Publisher Daniel McSweeney Editorial Director DanM Associate Russ Fields Publisher RussF Advertising Gary Pfaff Sales Manager GaryP Editor-in-Chief Janet Poveromo JanetP Managing Editor Shari Barbanel ShariB Associate Editor Nicholas Saraceno NicoS Contributing Writers James Gormley Todd Pauli Suzanne Shelton Art Director Robert Certo Production Manager RobertC Production Assistant Bryan Zak Graphic Designer BryanZ Circulation Manager Rosie Brodsky Rosie A PUBLICATION OF VRM MEDIA President Daniel McSweeney VRM Media 431 Cranbury Road Ste. C East Brunswick NJ 08816 Phone (732) 432-9600 Fax (732) 432-9288 Email info Website VRM Media publishes Nutrition Industry Executive Vitamin Retailer Natural Practitioner and Fitness Trainer magazines. Subscription Customer Service To order a subscription or manage your account please contact us at Nutrition Industry Executive P.O. Box 15026 North Hollywood CA 91615-5026 USA Phone (818) 286-3170 Fax (800) 869-0040 niecs Back Issues See the Table of Contents page for price and ordering information. Connect With Us vitaminretailer vitaminretailermagazine company vrm-media vitaminretailermagazine vrm_media 4 Nutrition Industry Executive November December 2016 Go to jiaherb for info about this advertiser ConditionSpecific Healing Plants Herbal and botanical ingredient sales for supplements are blossoming. However adulteration remains at the root of suppliers and manufacturers worries. B Y J ANET P OVEROMO y all accounts botanical ingredient sales are strong and growing in the U.S. although providing and receiving quality ingredients is the ultimate hurdle for suppliers and branded product manufacturers. According to a report by Persistence Market Research the global market for botanical supplements grew from 45.1 billion in 2010 to 54.6 billion in 2013 and is expected to grow to 90.2 billion in 2020 noted Dan Lifton president of New York-based Maypro Proprietary Branded Ingredients Group. In terms of the United States market in September 2014 the American Botanical Council (ABC) noted that 2013 retail sales of herbal and botanical dietary supplements rose 7.9 percent to 6.032 billion the 10th year in a row that sales grew in the U.S. After a positive spike during the beginning of the new millennium we see botanical extract back at the forefront of the dietary supplements market said Golan Raz vice president of health and nutrition at New Jersey-based Lycored. B This ongoing growth seems to be directly linked to consumer demand. Being sourced from nature and potentially non-GMO (genetically modified organism) and organic quality botanical extracts meet few of the core existing trends. Specifically in 2015 and 2016 we see a steady growth that varies between 5 to 12 percent year over year. This is despite negative press from 2015 said Deanne Dolnick science director with Georgia-based TR Nutritionals. When consumers can actually feel results when they take a product they continue to take it and tell others of their positive experience. The market should continue to grow as long as suppliers manufacturers and contract manufacturers shift from a largely price-point focus to ensuring that they are providing the highest quality herbs and botanicals. If companies continue to cut corners this will likely result in additional regulatory and PR concerns and ultimately to a decline in this category due to lack of consumer confidence. What s Trending Like the overall dietary supplements market consumer trust is a leading factor when it comes to trends and news Raz agreed. The two most desirable pillars are quality scientific backup that demonstrates real-time efficacy and quality that can be evaluated and that is stretched from the source to the actual finished product. With these two drivers in mind high-end brands are looking for partners that invested in clinical programs and that are vertically integrated all the way to the farms. Randal Kreienbrink vice president of marketing and certified food scientist with California-based BI Nutraceuticals concurred and noted that over the past two years key elements for the health of the herbal and botanical industry are the identity of the botanicals through DNA testing and evolving and building a stronger trust element with today s consumers. Science and traceability are key to the credibility safety and trust of the botanical nutritional supplement industry he said. 6 Nutrition Industry Executive November December 2016 Go to albion for info about this advertiser ConditionSpecific Another trend over the past several years according to TR Nutritionals is a significant increase in requests for Indian botanical extracts and powders Dolnick said. To better support our customers we have recently partnered with Prakruti Products a premier manufacturer of Indian botanicals as their exclusive U.S. representative. Indian botanicals are taking a strong foothold in this segment she added. Although some of these ingredients have been in the marketplace for many years their growth is trending upward. These botanicals include turmeric garcinia and bacopa. One of the most frequent requests that TR receives is for organic extracts whether from India or other growing regions. Prakruti s extracts and powders allow TR to keep up with the organic trend. body composition by reducing body fat mass. As a wellness brand Lycored is focused on five health indications according to Raz cardiovascular skin s beauty and health men s prostate women s bone and healthy sustainable vision adding that Lycored has recently published in leading scientific magazines comprehensive clinical results on both cardiovascular health (specifically post-meal lipids management) and skin s beauty and health. Proteins are key for weight gain as well as weight regulation. Phyto nutrients target various conditions for well being. And traditional botanicals remain notable. Dolnick said that ginkgo has been one of the most popular extracts for many years. There are numerous published articles in the public domain supporting its use for mild cognitive impairment that includes memory problems and issues with concentration. With the elderly population growing at a faster rate than any other we should continue to see significant growth with this extract. She added that turmeric standardized to 95 percent curcuminoids has been shown to have many different functions. However it is primarily sold as an anti-inflammatory which then lends itself to address osteoarthritis as well as overall immunity. She added that Garcinia cambogia standardized to 50-65 percent hydroxycitric acid (HCA) has many peerreviewed published articles to support its effectiveness. Garcinia has been shown to help the body store less fat and control appetite. Another Indian ingredient Bacopa monnieri is shown to support cognitive function by protecting the brain from oxidative damage. Cognitive function is becoming a category that cannot be ignored by any company she said. Indian botanicals are taking a strong foothold in this segment. Although some of these ingredients have been in the marketplace for many years their growth is trending upward. -- Deanne Dolnick Science Director TR Nutritionals Lycored s team together with leading universities from the U.S. France Scotland and Germany performed a list of clinical trials with hundreds of participants Raz said. The one core idea that stands behind this investment is the ongoing commitment to bring to the market natural products that are quality and affective and that were all scientifically evaluated and proven to work. Lycored s most recent publication on cardiovascular health ( index.php fnr article view 32537) demonstrates that 14 days of Lycored nutrient complex for heart (also known as Cardiomato) with as little as one soft gel daily reduces oxidize LDL cholesterol that is associated with high fat meal as well as other important parameters. Also significant are vegan proteins with a lot of interest in pumpkin seed faba bean and lentil proteins said Kreienbrink. Super fruits and vegetables are also big to fulfill needed nutrients and phyto chemicals he said. Proteins are the building blocks of life. Addressing Conditions Specifically With a maturing population in a stressinducing world maintaining health and wellness is top of mind for consumers Lifton said. As natural and herbal products are also becoming more and more popular it is important that the industry understands which health categories are trending among consumers. Maypro offers proprietary-branded ingredients that target some of the most commonly sought-out health categories. For example cognitive health is a huge concern in the aging population so Maypro offers Bluenesse a proprietary extract of lemon balm that supports cognitive performance by targeting focus alertness and memory. Unlike other cognitive health ingredients in the industry Maypro s Bluenesse does not cause drowsiness and takes effect within an hour of consumption. Lifton added that mood is another thriving category in which Maypro offers Venetron a patented powdered extract of Apocynum venetum. Venetron promotes a positive mood helps to alleviate occasional stress and improves sleep quality by working in synergy with GABA to calm brain excitation and increase serotonin levels. People are also always looking for safe and effective weight-management products often not knowing whether they can trust what is on the market Lifton added. Alluvia Purple Tea a new variety of Camellia sinensis has been shown in human clinical studies to support healthy weight loss and improved 8 Nutrition Industry Executive Botanical Ingredient Success In terms of what s new what we are seeing said Dolnick is more innovative combinations of botanicals with the efficacious dose of all ingredients. This allows the consumer to buy one multiingredient botanical product and that s a huge benefit. TR s customers can purchase all of their botanicals in one place. This too is important as more manufacturers and contract manufacturers are trying to decrease their number of suppliers. It s much easier for these companies to have a few suppliers on which they can depend for the highest quality raw materials than to have to constantly be seeking out different suppliers manufacturers that must be audited. In 2016 alone Lycored introduced new technologies in the heart skin and beauty and healthy vision areas. These technologies are all natural and nonGMO and are all supported by welldesigned and executed clinical programs. (Continued on page 24) November December 2016 Go to comar for info about this advertiser IndustryNews The Supplement OWL Has Landed T he Supplement OWL (Online Wellness Library) is now accepting product labels from dietary supplement finished product manufacturers and marketers as the product registry moves into its phase two of betatesting. Nine companies served as original beta-testers working with UL the global independent safety science company who is developing and administering the Supplement OWL to improve the process of inputting product labels. According to Erik Eberhart of UL It was incredibly helpful to have these companies test the product registry and their input allowed us to better understand where the challenges were and how we needed to meet those challenges to improve the product. The Supplement OWL is now moving beyond the original beta-test and the Council for Responsible Nutrition (CRN) who is providing the initial funding and has been coordinating efforts with the industry is urging companies to test out the product by inputting labels into the product registry prior to its public launch in January. Duffy MacKay ND senior vice president scientific and regulatory affairs advised Our goal is to make this process as efficient and easy as possible and the sooner companies start the process the more we can all learn together how to reach that goal. This important phase will demonstrate the scalability of the Supplement OWL a necessary component for the product registry to become a valuable resource for its intended audience of regulators retailers the industry and ultimately consumers. Once there are a substantial number of product labels incorporated into Tier 1 of the Supplement OWL it will be launched publicly and available at no charge. Tier 1 will include a copy of the complete product label and various fields of information about the product including ingredients brand name allergen statements number of servings and more. Participation in this tier is free for any company who is willing to supply the required information about its products and will be accessible online at no charge to the public. There are two additional important elements in Tier 1 1) Companies will be required to provide manufacturing and packaging facility contact information accessible only to FDA (U.S. Food and Drug Administration) and 2) each product entered will generate a unique product identifier which will have potential use as the Supplement OWL gains traction among its various audiences. UL in consultation with CRN and other industry leaders will soon begin developing Tier 2. CRN President and CEO Steve Mister commended UL and those companies--both CRN members and nonmembers--who have put in so much effort to date to ensure that the Supplement OWL is meeting its targeted deadlines and keeping the project moving forward. This is a case of the industry demonstrating its cooperation its maturity and its willingness to add self-regulatory initiatives to supplement government regulation. For more information visit AHPA Issues Slack-fill Guidance he American Herbal Products Association (AHPA) has published slack-fill guidance to help the regulated supplement industry inform consumers and comply with all relevant federal requirements. The difference between the capacity of a container and the volume of product inside is known as slack-fill. The U.S. Food and Drug Administration (FDA) regulates how food (including dietary supplement) containers are filled to packaging that could mislead consumers about the quantity of a product they are purchasing. AHPA s guidance provides best practices for industry to help companies ensure that packaging accurately informs consumers about the T quantity of product in containers and comply with relevant federal regulations. The guidance provides an overview of slack-fill laws and regulations a discussion of practical considerations and exemptions for packagers of food and dietary supplement products and answers basic questions about compliance with federal slack-fill regulations. Among other topics the guidance explores When slack-fill is misleading How much empty space is too much Use of transparent panels and windows Functional slack fill exemptions Unavoidable product settling during shipping and handling A number of factors often outside a company s control can cause a gap between a package s capacity and the actual amount of the product inside said AHPA President Michael McGuffin. It is important for companies to understand these factors and what they can do to mitigate them so customers know how much product they are purchasing. To download AHPA s Slack-fill Guidance visit portals 0 pdfs 2016%20pdfs ahpa_slack -fill_guidance.pdf ver 2016-11-01150128-850. 10 Nutrition Industry Executive November December 2016 Bergstrom Nutrition Among First in Supplement Industry to Receive New ISO 9001 2015 Certification ergstrom Nutrition (Vancouver WA) has announced that it has received the new ISO 9001 2015 certification three years ahead of schedule. The ISO 9001 is the International Organization for Standardization s (ISO) flagship quality management systems standard. The voluntary certification helps organizations demonstrate to customers that they offer products and services of consistently good quality. Companies holding the current version of this certification (ISO 9001 2008) have three years to update their standards to continue to keep it essentially moving into ISO 9001 2015 status. Bergstrom Nutrition s early adoption of the new requirements not only demonstrates its commitment to providing pure quality products but it also displays the MSM (methylsulfonylmethane) manufacturer s industry leadership as one of the first supplement companies to receive the new certification. The ISO 9001 and FSSC 22000 audits were conducted by AIBI-CS part of AIB International--a food-sector technology and information transfer center founded B in 1919. Over the last six years Bergstrom Nutrition has demonstrated a well-developed and impeccably-implemented food safety and quality management system. The company s committed management team continually improves upon this system building a food safety culture that is widely respected among industry peers said Alfonso Capuchino general manager of AIBI-CS. We take quality control very seriously at Bergstrom Nutrition so it wasn t a stretch to be able to meet the new standards so quickly. If we hadn t already had the FSSC 22000 certification this process would have been much more labor-intensive added Will Kitchen director of engineering quality and regulatory affairs Bergstrom Nutrition. However this was not an overnight process. Effort was made across the entire organization to raise our system up to the new standard. The new version places heightened importance on risk analysis and mitigation--key components of food safety standards. Evaluating all the risks that affect both Bergstrom Nutrition and our customers businesses has been a creative and worthwhile undertaking said Kitchen. ISO is an independent non-governmental international organization with a membership of 162 national standards bodies. Through its members it brings together experts to share knowledge and develop voluntary consensusbased market-relevant international standards that support innovation and provide solutions to global challenges. Abiding by all types of standards is the most important service we can provide our customers so their confidence in safety and regulatory compliance remains strong. More importantly this confidence trickles down to end-users-- consumers said Tim Hammond vice president of sales and marketing Bergstrom Nutrition. The newly robust standards serve as a backbone to a good quality management system that will drive organizations to provide improved levels of quality. For more information visit DSM Offers Global Nutrition Insights in New Book SM (Heerlen The Netherlands) and Sight and Life Foundation-led editorial board have launched a new book to provide the latest perspectives on the nutrition challenges that are now common to all societies worldwide. It argues that the case for good nutrition for all people in all parts of the globe and throughout the entire lifecycle is growing stronger and includes contributions from some of the world s most influential and respected experts in the field. Good Nutrition Perspectives for the 21st Century explores the economics of nutrition and malnutrition and discusses a wide range of tried and tested evidence-based approaches and interventions that can improve the nutritional status of the general population as well as at-risk groups. From topics such as consumer food choices to ensuring good nutrition for vulnerable population groups a range of experts from diverse organizations have contributed insights. Good Nutrition Perspectives for the 21st Century builds on a previous publication The Road to Good Nutrition D which was awarded first prize in the health and social care category of the British Medical Association (BMA) annual medical book awards. However this book differs from its predecessor in two essential respects said Professor Manfred Eggersdorfer senior vice president Nutrition Science and Advocacy at DSM Nutritional Products. Firstly it is set firmly within the context of the United Nations (UN) Sustainable Development Goals (SDGs) which were officially ushered in on January 1 2016. Secondly it pays attention to both the developed and the developing world. As a result it juxtaposes the nutrition challenges of different world regions in order to highlight the differences in nutrition status as well as the many problems that are now common to populations across the globe. Ertharin Cousin executive director of the UN World Food Program added This book collects some of our bright- est minds and best ideas but in addition it represents one of the most precious ingredients for our success in achieving the Sustainable Development Goals the global sharing of knowledge innovation and creativity. Good Nutrition will appeal to the general reader seeking a comprehensive overview of this complex and rapidly evolving field and will also provide inspiration for the specialist wishing to pursue a specific avenue of investigation with the help of an experienced and trustworthy guide. The publication has been developed as part of DSM s on going work to raise awareness of the importance of improved nutrition amongst key stakeholders globally and will be launched initially at the CFS43 Plenary of the UN Committee on World Food Security. The full text of Good Nutrition Perspectives for the 21st Century may be downloaded at en_us home.html. Nutrition Industry Executive 11 November December 2016 IndustryNews Dr. Bronner s Resigns From OTA Announce Initiatives r. Bronner s (California) has resigned from the Organic Trade Association (OTA) citing the association s betrayal of the consumer-led GMO (genetically modified organism) labeling movement and general drift away from the core principles that drive the organic movement. According to the company the OTA compromised their initial position of opposition to the DARK Act and lent the crucial support that allowed anti-labeling legislators to push that same legislation through the Senate and be signed into law by President Obama this summer. Following the resignation Dr. Bronner s has pledged to instead use its organizational resources to help power consumer farmer and industry organizations that more authentically and courageously represent the vision of regenerative organic agriculture versus the disaster of soil destroying industrial agriculture. D While maintaining its commitment to strategic progressive initiatives in general Dr. Bronner s also said it is pleased to be deploying resources to help campaigns win minimum wage cannabis reform and animal welfare battles in various states this November. Dr. Bronner s donated 250 000 to the Fairness Project to support campaigns to lift the minimum wage to 12 by 2020 in Colorado Arizona and Maine and 13.50 in Washington. Dr. Bronner s was also active in the campaign to raise the minimum wage in Washington D.C. to 15 by 2021 which achieved victory in June of this year and also celebrated major movement victories in Oregon California and New York earlier this year. Dr. Bronner s working with allies New Approach and the Marijuana Policy Project dedicated more than 660 000 into responsible cannabis Go to herballyyours for info about this advertiser 12 Nutrition Industry Executive legalization and regulation campaigns in California Massachusetts Maine Arizona and Nevada. The company said that will exert enormous pressure on federal lawmakers to end the racist outdated policy of cannabis prohibition that shreds productive citizens lives and families for no good reason and focus law enforcement resources instead on actual crime. Dr. Bronner s working with allies at the Humane Society of the United States recently gave 100 000 to the Yes on 3 campaign in Massachusetts to end the cruel confinement of veal calves egg-laying hens and pigs in that state. Looking forward Dr. Bronner s is particularly keen to help power and coordinate the animal welfare and regenerative organic movements in their common aim to end the horribly cruel and unsustainable factory farming of animals fed by monoculture deserts of carbon and water intensive grain added Cosmic Engagement Officer (CEO) David Bronner. Onethird of the Earth s surface is covered in arable farm and range land. Regenerative practices can restore soil health and organic matter relatively quickly and coupled with a global commitment to eating much less but much more humane and sustainably raised animal products can also significantly mitigate climate change. For more information visit November December 2016 Court Finds LeanSpa Marketer Responsible for Deceptive Claims T he U.S. Court of Appeals for the Second Circuit has upheld a lower court ruling requiring the operator of an affiliate marketing group to pay 11.9 million for its part in helping to promote LeanSpa a deceptively marketed weightloss supplement. In issuing its ruling the Circuit Court found that LeadClick Media LLC recruited affiliate marketers that used fake news sites to drive internet traffic to the LeanSpa website. LeadClick knew that the news sites were phony and actively participated in creating their content. The decision is the first by a court of appeals holding the operator of an affiliate marketing network liable for deception by third-party marketers. LeadClick knew its affiliates were lying to consumers and took steps to help make those lies more effective said Jessica Rich director of the FTC s (Federal Trade Commission) Bureau of Consumer Protection. The Circuit Court s ruling goes a long way toward ensuring that affiliate networks can t hide behind claims of immunity when their consumer fraud is exposed. In the ruling the Circuit Court also found that LeadClick bought advertising banner space from legitimate online news sites with the intent to resell it for use with fake news sites thereby increasing the likelihood that a consumer would be deceived by the content. Separately the Court found however that relief defendant CoreLogic Inc. LeadClick s parent company could not be held liable for 4.1 million that it had collected from LeadClick and was sought by the FTC to provide consumer redress. In granting the FTC s request for summary judgment the court ordered LeadClick to disgorge the 11.9 million it received from LeanSpa as payment for its affiliate marketing services. It also ruled that LeadClick s parent company CoreLogic had to disgorge 4.1 million in ill-gotten gains it received from LeadClick as part of the 11.9 million total judgment. LeadClick and CoreLogic appealed the district court s ruling leading to the circuit court decision. For more information visit evoxx Technologies Launches Website Following Aevotis and Evocatal Merger E voxx technologies GmbH a German industrial biotechnology company focusing on the development and production of enzymes and novel carbohydrate ingredients has announced the launch of its new The website offers a complete company and product overview in German with English translation. evoxx technologies with two locations in Germany--on the creative campus in Monheim am Rhein and on the biotech campus Hermannswerder in Potsdam was formed following the acquisition of aevotis GmbH by evocatal GmbH. The new company s vision is to become a leading provider of innovative enzyme and carbohydrate products for the nutritional health and wellness markets. A strong patent protected technology platform enables the development and marketing of exclusive carbohydrate oligomers and polymers for the global food market. In the functional food market we see an increasing demand for novel ingredients with strong scientifically supported health benefits said Dr. Thorsten Eggert evoxx managing director and chief executive officer. To meet the needs of its customers the food industry needs novel and multifunctional ingredients which are in line with recent scientific findings and studies on healthy diets and we have the enzyme technology to do it. evoxx technologies GmbH will use its competitive enzyme and carbohydrate development expertise in applications to target the negative health effects of commonly over-consumed carbohydrates such as sucrose glucose fructose and or from inadequate amount of dietary fiber. Within the next three years evoxx will bring more healthy carbohydrates into the glass and onto the plate of the consumer by using enzymes and ingredients from the evoxx pipeline said Eggert. For more information email t.eggert Go to hsus for info about this advertiser Nutrition Industry Executive 13 November December 2016 IndustryNews Sabinsa and Chemill Reach Licensing Agreement abinsa Corp. (East Windsor NJ) and Chemill Inc. (Bothell WA) have reached an agreement which resolves a previous lawsuit for infringement of Sabinsa s U.S. Patent No. 6 653 327 covering compositions and uses of turmeric-derived tetrahydrocurcuminoids. The matter has been settled on undisclosed terms. Chemill will respect the patent as a due licensee. We are pleased that this matter has been resolved and look forward to a mutually beneficial relationship with Chemill said Sabinsa founder Muhammed Majeed PhD. We sincerely appreciate Chemill s goodwill and the S way they have handled this issue. It is encouraging that Sabinsa and Chemill came to a quick and amicable resolution of this matter as reflected in the Consent Judgment filed with the court so that Sabinsa did not have to resort to further legal action stated James H. Hulme litigation counsel for Sabinsa. Sabinsa s patent covers compositional claims and also several topical and oral applications of tetrahydrocurcuminoids noted for their high antioxidant capacity. For more information visit Axiom Foods Expands Global Footprint to Produce Rice Bran Oil in India xiom Foods (Los Angeles CA) is now expanding into India to produce hexane- and ethanol-free natural rice bran oil and a variety of stabilized rice bran ingredients for the human food and animal feed sectors including the equine market. Axiom is known for developing a chemical-free enzymatic fractioning process of brown rice and mechanically fractioned pea protein which were recently awarded with FDA (U.S. Food and Drug Administration) GRAS (generally recognized as safe) approval and are featured in thousands of food products. In India Axiom has identified specific varietals of rice conducive to the production of rice bran and rice bran oil using wholly coldpressed mechanical manufacturing a process which sets Axiom Foods apart from the competition who use hexane and ethanol for their extraction processes. The product cost will be approximately 25 percent less than anything on the market. The newest office and manufacturing plant are based in India. Stabilized rice bran oil is a rich source of fat that includes a m lange of B vitamins phosphorus and also contains gamma Oryzanol which those in the horse racing industry have lauded for its equine muscle building properties. According to Global Market Insights the global rice bran oil market size was estimated at more than 1.2 million tons in 2015. The global edible oil market size was estimated at more than 165 million tons in 2015. The Indian rice bran oil A market size by the end of 2016 is forecasted to be over 600 million (USD). Our natural process will offer the food and equine feed industries not only a chemical-free and nutrient-rich product but at a cost savings of at least 25 percent less than what the competition is able to offer said David Janow CEO of Axiom Foods. We have identified a varietal of Indian rice as having the highest yield of oil and nutrients and the massive source meets our strict quality testing requirements. Building this facility is a sustainable expansion as it eradicates having to ship rice across the world for processing. Commercial quantities will be reached within six months and following we will also fraction protein from the bran layer. With the addition of these products and facility Axiom Foods will help lead the rice bran ingredient industry. We are proud to be able to offer these superlative natural ingredients at an affordable cost we re on a mission to change the face of the global food ingredient market. For more information visit 14 Nutrition Industry Executive November December 2016 Deerland Enzymes Opens New Probiotics Manufacturing Facility eerland Enzymes (Kennesaw GA) has announced the official opening of its new stateof-the-art facility dedicated exclusively to manufacturing probioticbased supplement products. Production at the new Deerland Probiotics facility has begun and the company celebrated with a ribbon-cutting ceremony this week. The ceremony was attended by more than 70 guests comprised of several government officials and members of the local community including Congressman Barry Loudermilk and representatives from Senators Johnny Isakson and David Perdue s offices. Also in attendance was Mayor Derek Easterling of Kennesaw along with many officials from the City of Kennesaw and the Cobb Ravech (L) with Congressman Loudermilk County Chamber of Commerce. Many of the company s key venSince 2008 Deerland Enzymes has dors customers and trade association experienced remarkable growth drivrepresentatives were also present for en by a focus on science and innovathe ceremony. tion and developing new technoloTo accommodate the growing gies supported by human clinical demand for high quality probiotic studies. This is an exciting milestone supplements the 30 000-plus-squarefor us said Scott Ravech Deerland s foot facility will be focused solely on CEO. We count ourselves fortunate producing probiotics in their ideal to be in a business where we can environment. The facility is constructmake an appreciable difference in the ed with best-in-class building materiquality of people s lives through the als and technology to provide 24 7 products we develop and manufacmonitoring of temperature and ture and it gives me great pride to humidity control. In addition all prolead this exceptional team at duction clean rooms are outfitted Deerland Enzymes into this next with wall panels that feature antibacchapter of our company s history of terial properties. Environmentally success. friendly the thermal and airtight Deerland will continue to manufacbuilding system reduces operational ture enzyme-based supplements in its energy demands (heating and coolcurrent facility while moving all proing) and as a result its carbon footbiotic-based production to the new print. facility. As their needs grow our cus- D Ornua Acquires U.S. Dairy Ingredients Business rnua Ireland s largest exporter of Irish dairy products has announced it has acquired the CoreFX Ingredients division of MCT Dairies Inc. and a powder ingredient production facility in Orangeville IL. The acquisition which has been made in partnership with Denis Neville formerly of MCT Dairies is Ornua s first specialty dry ingredients production facility in the US. The newly named business CoreFX Ingredients LLC complements Ornua s existing ingredients production facilities in the U.S. U.K. Spain and Saudi Arabia delivering scale and shared dairy technologies. Headquartered in Chicago IL CoreFX Ingredients uses spray-drying and dry-blending technologies to produce a range of dairy cheese and lipid powder ingredient solutions for U.S. food manufacturing and foodservice customers. It serves a wide range of markets including snack foods sports nutrition soups sauces and dressings infant and toddler nutrition desserts bakery and dairy. Central to the business is the ability to design ingredients specific to customer requirements across a range of properties including taste melt point texture mouth feel cost and shelf stability. Ornua plans to further increase the scale and capability of the CoreFX Ingredients business through customerled innovation dairy technologies and its team expertise. It is investing in the development of the production facility s technical capabilities and in a Customer Innovation Center at its Chicago headquarters. This acquisition is another key milestone in Ornua s U.S. expansion program and is in line with our strategy to invest in high-growth and profitable dairy businesses said Kevin Lane Ornua CEO. CoreFX Ingredients will provide our Ingredients Division with greater scale and will enhance our capability to deliver customized ingredient solutions to our customers. Importantly we can share its dairy technologies across all of our ingredient operations around the world and in turn drive growth. For more information visit O tomers can continue to trust that their formulations are being manufactured in a safe cGMP (current good manufacturing practice) environment and can rest assured that their probioticbased products are manufactured in a world class facility designed specifically for probiotics said Ravech. For more information call (800) 697-8179 or visit November December 2016 Nutrition Industry Executive 15 IndustryNews Wellomics Drives R&D Change by Combining Science Product Development and Commercialization ellomics based in Maine creates partnerships to accelerate the development of food supplements functional foods beverages and personal care products. Wellomics proprietary formulation technologies to maximize bioavailability and pinpoint market research to ensure brand differentiation make its products unique. Our products combine science technology and IT with nature to create products that impact bodies at a cellular level said Mark Neveu PhD Wellomics founder and former CEO of the National Foundation of Alternative Medicine. At the heart of Wellomics business-tobusiness model is a commitment to use W rigorous science with proprietary omics research capacities to provide the latest cutting-edge formulations. In addition Wellomics backs up its formulations with validation studies on products so consumers can rest assured that they are getting the desired results--that is--increasing their healthspans. Wellomics is well positioned within the academic and commercial R&D industry with its offices located at University of New England s School of Pharmacy and pending collaboration with Harvard Medical School and other prestigious scientific institutions. Introducing the Wellomics team s experience to our industry is an opportunity for us to collectively change the paradigm for the better in dietary supplements said Eric Schnell business development partner. Our team is excited to create new relationships within our industry including new start-ups such as Yogi Cameron Ayurveda and larger established brands in the industry. For more information visit joins HORN with more than 10 years Mark G. Walin a former New Jersey-based BENEO of sales experience serving broad Abbott and Perrigo execuannounced that Christoph markets including the food industry. tive has joined BIO-CAT Boettger has been appointed Ecuadorian Rainforest a wholesale (Troy VA) and BIO-CAT as a new member of the execingredients supplier in Belleville NJ Microbials as the vice presiutive board of directors at has promoted Ramon Luna to marketdent of sales and marketing BENEO GmbH. At the same ing coordinator for the company. With for both companies. time Hildegard Bauer who the company since 2013 Luna has BrandHive (Salt Lake City was a member of the execuChristoph worked in the marketing UT) has hired Ryan tive board at BENEO for the Boettger department alongside the Hogan as its media past 10 years has retired from company s vice president communications manager. business after 38 successful years Steve Siegel. Hogan is a marketing adverwithin the S dzucker Group. In his FCC Products Inc. tising and communications new role Boettger is leading all areas (Livingston NJ) has appointprofessional with more than of operations including technical ed Vladimir Rios to the newly 10 years of experience in affairs raw material product safety created position of chief broadcast digital marketing and quality as well as the BENEOand media purchasTechnology Center. Vladimir Rios operating officer reporting directly to Gerard Woods ing. In his new posiAdditionally BENEO has owner and president. In his tion Hogan will be named Denisse Colindres new role Rios will be responresponsible for digital as manager nutrition commsible for the daily operations and print media unication for the North Amerimarketing and the projected research planning can Region. In her role growth with existing and new buying and traffic as Colindres will be communicatcustomers. well as sponsorships ing the nutrition research that Denisse ChromaDex Corp. (Vine and event marketing substantiates the health beneColindres CA) has appointed Matthew for BrandHive s growfits of BENEO s functional Nick Gray Roberts PhD to the compaing client base. ingredients from natural ny s Scientific Advisory Board HORN (La Mirada sources. (SAB). Roberts has more than 25 years CA) recently announced the NattoPharma (Metuchen of success at the industry s major comhire of Nick Gray as account NJ) has announced the addipanies. Currently he is managing manager for HORN tion of Collene Villalobos to its growing and advising startup compaFoodTech. Based in Dallas sales team. Prior to joining nies across the food nutrition and TX Gray will provide techniNattoPharma as sales managdigital health industries. Roberts will cal sales support to food er Americas Villalobos Collene add further operational development technologists in Texas and worked with Chromadex for Villalobos and discovery experience to the SAB. other Southwest states. Gray eight years. 16 Nutrition Industry Executive November December 2016 You reHired IngredientNews Research Shows GanedenBC30 Probiotics Improve Digestion of Plant Proteins lready known as the only probiotic strain scientifically shown to enhance protein utilization according to the company new research confirms that GanedenBC30 increases digestibility for pea rice and soy proteins. The findings are being released less than two months after Ohio-based Ganeden s 24th study was published confirming that the patented and science-backed strain enhances the body s utilization of animal-based protein and helps with muscle recovery. In the study which was conducted by Dr. Koen Venema from Maastricht University in the Netherlands the digestion of soy pea and rice protein A were measured with normal digestive enzymes as compared to these enzymes with 1 billion CFU of GanedenBC30. It was found that the presence of GanedenBC30 increased the total nitrogen levels as well as Alpha Amino Nitrogen (AAN) which is a proxy for free amino acids and small peptides meaning the probiotic aids in the digestion of plant proteins and the breakdown of peptides. It also provides better utilization of amino acids and reduces unabsorbed protein delivery to the colon where protein fermentation could lead to the production of toxic metabolites. For more information visit CurcuWIN Bioavailable Curcumin Obtains Self-affirmed GRAS mniActive s (New Jersey) highly bioavailable curcumin CurcuWIN has received selfaffirmed GRAS (generally recognized as safe) notification by an expert panel who evaluated the ingredient in accordance with stringent U.S. Food and Drug Administration (FDA) safety criteria. OmniActive remains steadfast in delivering innovative effective and safe ingredients to the marketplace said Lynda M. Doyle senior vice president of global marketing OmniActive. CurcuWIN is a truly differentiated ingredient in the increasingly crowded ehanced curcumin market because our robust clinical program is showing how its higher bioavailability correlates to greater efficacy at a lower dose--what we ve termed bioavailability with a purpose. And now by gaining GRAS self-affirmation CurcuWIN sets itself apart yet again. In a well-controlled human clinical trial--the first curcumin study of its kind--comparing commercial curcumin products CurcuWIN increased relative absorption of total curcuminoids 46 times over standard curcumin. CurcuWIN was also significantly more bioavailable than other enhanced forms. Moreover in the recent ground-breaking FloMeD (flow mediated dilation) CurcuWIN was shown to help support healthy blood flow and circulation at a low dose. For more information visit O ADM Launches New Line of Fruit Vegetable Functional Extracts llinois-based Archer Daniels Midland Company (ADM) introduced a new line of extracts that can deliver a concentrated dose of the powerful antioxidant compounds beta-carotene and anthocyanins in a variety of food beverage and supplement applications. Beta-carotene is a precursor for vitamin A which is an essential nutrient that plays a role in maintaining eye and skin health. ADM s beta-carotene-rich vegetable extracts originate from carrots pumpkins sweet potatoes paprika from chili peppers and Reishi mushrooms. Anthocyanins are antioxidants that may help maintain a healthy immune system. ADM s anthocyanin I extracts originate from purple sweet potatoes purple maize purple carrots beets rhubarb tomatoes and red cabbage. These new extracts deliver key phytonutrients from vegetables while at the same time providing an optimal sensory experience and a clean-tasting profile. They are soluble for a variety of food beverage and supplement applications and can be used in applications ranging from beverages confections frozen desserts snacks bars baked goods supplements among others. For more information visit Vitamin K2--Not K1--Shown Again to Impact Cardiovascular Health linical Nutrition has published a new long-term study1 that explores if there is a relationship between intake of phylloquinone and menaquinones (vitamins K1 and K2 respectively) and all-cause and causespecific mortality. The results showed that high intake of menaquinones (vitamin K2) was associated with a reduced risk of CHD (coronary heart disease) (at least in hypertensive participants) while high intake of phylloquinone (vitamin K1) was not associat- C ed with any reduced risks. For more information visit or References 1 Zwakenberg SR den Braver NR Engelen AIP Feskens EJM Vermeer C Boer JMA Verschuren WMM van der Schouw YT Beulens JWJ. Vitamin K intake and all-cause and cause specific mortality. Clinical Nutrition. 2016 Aug 30. Pii S02615614(16)30216-3. 15-20. DOI 10.1016 j.clnu.2016.08.017. Nutrition Industry Executive 17 November December 2016 IngredientNews Curcumin Extract Found to Counteract Inflammation at the Genetic Level ew biomedical research released jointly by The Rhema Group (BC Canada & Utah) and Biologic Pharmamedical (Vancouver BC Canada) has shown that a trace component of the standard curcumin extract bisdemethoxycurcumin (BDMC) is proven to be up to seven times more potent on a key antiinflammatory target than the curcumin extract itself. This discovery is signifi- N cant because it means curcumin pharmacology can now be more precisely targeted for therapeutic results. The Rhema Group s chief science officer Franco Cavaleri BSc PhDc who is also the principal research scientist at Biologic Pharmamedical made the patent-pending research discovery. Cavaleri is currently completing a doctoral degree in experimental medicine at UBC s (University of British Columbia) Faculty of Medicine Center for Brain Health. Cavaleri s research has proven for the first time how the modified curcumin extract targets and neutralizes a key protein central in the regulation of inflammation while significantly enhancing the efficacy of the antiinflammatory properties of curcumin. For more information visit or Pycnogenol Helps Curb Muscle Loss Due to Aging new peer-reviewed published study shows French maritime pine bark extract Pycnogenol (Switzerland) may be effective in curbing muscle loss that occurs with aging a natural process that leads to sarcopenia a common condition affecting adults as early as age 65. The study published in the September 2016 Journal on Orthopedics and Traumatology revealed that daily supplementation with Pycnogenol helps to stabilize muscles through this natural process and supports muscular function and endurance. According to the National Library of Medicine physically inactive individuals can lose as much as 8 percent of muscle mass each decade after 30. Those who are physically active can maintain more muscle mass yet are still affected by muscle loss due to aging. Muscle loss due to aging can affect even the most active individuals and can result in feelings of weakness and frustrating fatigue which can interfere with our daily activities. This natural process is why opening a jar of pickles gets harder as we get older. We have less muscle to work with so our muscles must work harder and thus we get tired faster said nationally known natural nutrition expert Dr. Fred Pescatore. For more information visit A Published Study Shows Kemin Spearmint and Rosemary Extracts Improve Learning and Memory in Mice recently published medical school study shows Iowabased Kemin s proprietary antioxidant-based ingredients spearmint extract and rosemary extract improve learning and memory in SAMP8 mice. The study also revealed reduced brain tissue markers of oxidative stress providing the first indications of how these potent extracts may act in the brain to improve cognitive performance. The study Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice conducted at St. Louis University School of Medicine Division of Geriatrics was published in Physiology and Behavior in August 2016. In this study researchers evaluated the effects of a spearmint extract (5 percent rosmarinic acid) and two rosemary extracts (60 percent and 10 percent carnosic acid) on learning and memory in the SAMP8 model of accelerated aging. Three doses of actives for each extract were tested along with a placebo condition. For more information visit or A DuPont Nutrition & Health and Inbiose Partner to Bring Novel Infant Nutrition Ingredients to Market uPont Nutrition & Health (Missouri) announced a joint development and licensing agreement for exclusive rights to selected fucosylated human milk oligosaccharides (HMOs) including 2 -fucosyllactose with Inbiose a Belgium-based producer of specialty carbohydrates. This partnership is part of a new era in ingredients targeted for infant nutrition said John Rea global business unit leader for probiotics cultures D food protection and HMOs. With this development we re working toward fulfilling our corporate mission to help solve the world s food challenges by providing innovative ingredients our customers can use to make healthy and nutritious products. Our investment here complements the broad capabilities DuPont has built in probiotics and understanding the human gut microbiome as well as our technologies already targeting this area. HMOs are a group of unique oligosaccharides found in mother s milk with 2 -fucosyllactose being the single most abundant HMO. This new partnership combines Inbiose s innovative production platform for specialty carbohydrates with DuPont s capabilities in industrial-scale fermentation regulatory and health science expertise as well as global market access. For more information visit or 18 Nutrition Industry Executive November December 2016 TSI Group Launches Non-shellfish Glucosamine SI Group Co. Ltd. (TSI U.S. location in Minnesota) announced the launch of GlucosaGreenDFTM--the world s first non-shellfish glucosamine branded product line produced by an innovative and patent-pending direct fermentation technology. Glucosamine has grown over the years into one of the most popular and essential ingredients in the global joint-care category. Historically the production of glucosamine ingredients has been largely dependent on shellfish derived chitin as a starting material. T Unfortunately chitin has exhibited significant challenges such as a frequently unclear supply chain inconsistent quality and potentially harmful environmental impact due to manufacturing conditions. In addition shellfish derived glucosamine ingredients are not suitable for vegetarians and vegans and their uses are also prohibited by certain religions. According to TSI s CEO Joe Zhou The patent-pending direct-fermentation manufacturing technology that supports GlucosaGreenDF is considered disruptive since it effectively addresses and offers efficient solutions to all of the challenges inherent in shellfish derived chitin production processes. Zhou continued The GlucosaGreenDF process is a totally transparent fully traceable cost effective and environmental-friendly solution for brands and ultimately the consumer. For more information call (877) 549-9123 or visit Fruit d Or Nutraceuticals Premiers Wild Blueberry Powders ruit d Or Nutraceuticals (Quebec Canada) supplier of organic cranberries and wild blueberries is now inviting product formulators to call for samples and start working with its team to develop products using its new standardized whole-food wild blueberry powders. Fruit d Or is first to market with a clean field-to-table low-bush whole food wild blueberry powder confirmed Stephen Lukawski vice president of global business development and sales for Fruit d Or Nutraceuticals. We re gearing up for a busy international launch. Blue Naturelle Organic Wild Blueberry Powder and Blue d Or Conventional Wild Blueberry Powder will be ready to launch over the next 90 days. Both of these wild blueberry whole-food powders are nonGMO (genetically modified organism) vegan gluten free kosher and contain no additives excipients or carriers. With our proprietary processes the color flavor and aroma are preserved as Mother Nature intended Lukawski added. A substantial body of scientific research exists on wild blueberries health benefits for children and adults. Considered a super-antioxidant and king of blueberry wild blueberries are associated with eye health oral health and enhanced cognitive performance. Evidence shows they also promote cardiovascular health supporting healthy blood pressure and cholesterol levels. For more information call (888) 472-2275 or visit F Ethical Naturals Introduces Cranberex The Power of Oregon Cranberry alifornia-based Ethical Naturals Inc. (ENI) a supplier of botanical ingredients to the U.S. and international supplement market announced the release of Cranberex a standardized cranberry extract providing an exceptionally high concentration of cranberry s most active constituents the distinct proanthocyanidins (PACs) containing the A-type linkages that don t occur in PACs from other tannin-rich foods. Cranberex is thus connected to the latest analytical methods and clinical trials that demonstrate cranberry s abilities to support urinary tract health. C While the majority roughly 90 percent of American cranberries are produced in the Northeastern states a small percentage of U.S. cranberry is grown in the cool coastal areas of Oregon. The climate and harvest conditions in this Oregon area tend to produce darker red cranberries that are higher in PAC levels than Northeastern berries. It is these high PAC levels in the Oregon fruit as well as advances in manufacturing and analytical methods that form the basis of ENI s potent Cranberex product. Cranberries affect and support urinary tract health in a notable way the cranberry PAC s inhibit the adhesion of E.coli bacteria to walls of the urinary tract. Studies have confirmed that this effect is specific to the A-linked PACs (cranberry) but not to other PAC-rich foods with the more common B-type linkages (chocolate and grapes for example). For more information call (866) 459-4454 or visit Nutrition Industry Executive 19 November December 2016 IngredientNews Cardiomato Shown to Improve Cardiovascular Health ew Jersey-based Lycored announced the publication of its paper in the international peerreviewed journal Food & Nutrition Research. Within the paper scientists show that taking the carotenoid-rich tomato extract (CRTE) Cardiomato supplement for only two weeks inhibits the oxidation of low-density lipoprotein (LDL) the cholesterol most often associated with heart disease. Funded by Lycored the research carried out by scientists at Naturalpha Clinical Nutrition Center at H pital Saint Vincent de Paul furthers the assertion that whole food extracts are more effec- N tive than single standalone ingredients--such as lycopene. The study builds upon a growing body of research elucidating the role tomatoes play in cardiovascular health. Specifically the paper sheds light on a particular niche within this field of research how a specifically standardized tomato extract can support cardiovascular health by helping to regulate the stress response that naturally occurs after one eats which is something that can benefit everyone s health. For more information call (877) LYCORED or visit BENEO s Palatinose Enhances Memory and Mood in School-age Children cientific research carried out by Haley Young and David Benton from the Department of Psychology Swansea University Wales shows that a Palatinosebased breakfast beneficially influences children s memory and mood throughout the morning. The study highlights that starting the day with the right choice of carbohydrates can help children perform well at school. The randomized double-blind cross-over study was conducted with 75 school children between the ages of 5 to 11 years. On two occasions at least one week apart the children consumed a breakfast including cornflakes milk yogurt jam and orange juice. The meals were identical in calorie count as well as macronutrient composition and were either prepared with BENEO s New Jersey Palatinose or glucose (providing in total 41 g of carbohydrate). The children s mood and cognitive performance were assessed in test blocks one and three hours after breakfast. The results showed that although both groups of children initially did well after breakfast those consuming the Palatinose breakfast maintained significantly better memory performance later in the morning than those consuming the glucose-breakfast both in immediate and delayed memory tests. Moreover the children who had consumed the Palatinosebreakfast were in a better mood later in the morning i.e. rating their mood as significantly better compared to those who had eaten the glucose breakfast. For more information visit S Seipel Group Receives U.S. Patent on Urox he Seipel Group Pty Ltd. an Australian company committed to the research and development of specialized formulations to improve bladder control has been granted U.S. Patent No. 9 452 191 for Herbal compositions for the prevention or treatment of urinary incontinence and overactive bladder. Seipel Group has registered the U.S. trademark Urox for the formula a proprietary blend of Lindera aggregata Equisetum arvense and Cratevox (Crateva nurvala) which is sold by several US supplement companies under their own brands. Developed by Tracey Seipel ND a T naturopathic clinician and herbalist who has been combining traditional and scientific theories to develop treatment strategies and formulations since 1987 the Urox formula was developed through years of research into the prevalence and impact of bladder control issues for both men and women which affects up to 50 million Americans. For more information visit Ingredion Launches Liquid NUTRAFLORA L95-S Soluble Prebiotic Fiber ngredion Inc. (Illinois) a global provider of ingredient solutions to diversified industries announced that its NUTRAFLORA prebiotic fiber is now available in liquid form for ease of use. I The effectiveness of NUTRAFLORA prebiotic fiber is built on a foundation of more than 200 studies and 20 years of research. NUTRAFLORA prebiotic fiber has been scientifically demonstrated to support digestive and immune 20 Nutrition Industry Executive health provide a good or excellent source of fiber and can be used to reduce sugar in foods and beverages such as bars baked goods functional beverages and dairy products. By now offering NUTRAFLORA prebiotic fiber in liquid form we are helping manufacturers to simplify their operations said Marco Villone vice president of marketing U.S. and Canada for Ingredion Incorporated. By formulating with NUTRAFLORA L95-S soluble prebiotic fiber food developers have the ability to easily go beyond basic nutrition and bring consumers the fiber and digestive support they want. For more information visit Funded by BENEO and published in the European Journal of Nutrition in 2015. Young H Benton D (2015) The effect of using isomaltulose (Palatinose) to modulate the glycaemic properties of breakfast on the cognitive performance of children. Eur J Nutr 54 (6) 1013 1020. https 10.1007%2Fs00394-0140779-8. November December 2016 Clinically Documented Probiotics for Supporting Women s Health omen s health is a top consumer concern and dietary supplement sales for this category have consistently grown over the last five years. The most common vaginal infection that occurs in women ages 15-44 is bacterial vaginosis characterized as an imbalance of the vaginal microbiota caused by an overgrowth of atypical bacteria. The healthy human vagina is colonized predominantly with members of the genus Lactobacillus. A reduced proportion of lactobacilli in the vaginal microbiota is associated with disease or increased disease risk. W By combining Lactobacillus rhamnosus HN001TM (20 percent) and Lactobacillus acidophilus La-14 (80 percent) (5x109 CFU dose) DuPont Nutrition & Health presents a product designed to give women the ability to support vaginal health through maintenance of healthy vaginal microbiota. A product offering composed of the combination of HN001TM and La-14 can survive passage through the digestive system to successfully colonize vaginal cells. In a recent study by De Alberti D. et al. (Arch Gynecol Obstet (2015) 292 861 867 DOI 10.1007 s00404-015-3711-4) this capability was investigated in a double-blind placebo-controlled clinical trial involving 40 healthy women in Italy. For more information visit Nicotinamide Riboside Plays a Critical Role in the Path to Cellular Energy Production hromaDex Corp. (California) announced that an additional study recently published in the prestigious journal Nature Communications explained why NAD precursors (boosters) NR and nicotinamide mononucleotide (NMN) demonstrate similar metabolic benefits in mammals. The study conducted by a team including leading NAD researcher Dr. Charles Brenner found that effective supplementation with NMN depends on conversion to NR. NAD is a cellular co-enzyme critical for energy production and mitochondrial health. Because NAD declines in aging strategies for NAD repletion with B3 vitamins have become popular in order to maintain a youthful metabolism. Recent work also published in Nature Communications and led by Brenner unequivocally demonstrated that NR is not only the most efficient and effective B3 at upregulating NAD but it is also the most effective activator of longevity-promoting sirtuin proteins. NR is converted to NAD in a two-step process initiated by NRK1 a gene discovered by Brenner. Because the product of NRK1 is NMN Brenner noted that Some people believed that NMN would be better at boosting NAD levels because NMN comes after NR in the pathway. Their theory was that NMN could diffuse or be transported into tissues such as the liver and be directly converted to NAD . But that theory doesn t take into account how compounds get into cells Brenner explained. For more information visit Glanbia Nutritionals Launches Line of Heat-Treated Sprouted Seeds to Address Food Safety lanbia Nutritionals (Ireland) has launched the first line of fully traceable heat-treated sprouted seed ingredients in the market. Responding to industry concern of increasing outbreaks of foodborne pathogens in sprouted products Glanbia Nutritionals has developed ChoiceGrad Brown Sprouted MP and ChoiceGrad Golden Sprouted MP. They are the only sprouted ingredients on the market to offer such strong safety credentials. Produced following the industry-leading MeadowPure process of sourcing cleaning and sorting seeds this new line of ingredients also undergoes Glanbia Nutritionals robust MicroSure Plus heat treatment to ensure optimal purity stability and shelf life. Currently there are no officially regulated steps in the production of sprouts that prevent bacterial growth or completely eliminate pathogens. Aiming to address this gap Glanbia Nutritionals processes include a robust seed selection management and traceable supply-chain carefully controlled germination of mucilaginous seeds as well as air and water quality control. Low-heat drying steps lock in nutrients and ensure vitality of seed. A further validation process tests seed purity and the ability to germinate creating sprout seed ingredients with the highest safety and quality standards. For more information visit C G November December 2016 Nutrition Industry Executive 21 IngredientNews Study Shows Chia ALA Increases DHA Content in Mothers Milk During Pregnancy study published in Nutrients has shown that women who consume Benexia (Chile) chia oil one of the highest plant sources of omega-3 EFAs alpha linolenic acid (ALA) transferred high levels of DHA to their infants during breastfeeding. It is the first published study of its type involving pregnant and lactating women. The study developed by Dr. Rodrigo Valenzuela PhD Nutrition Department University of Chile and his team was aimed at measuring the transfer of fatty acids (ALA DHA EPA) to the fetus (blood phospholipids) and breast milk in women who sup- A plemented with chia oil during pregnancy and lactation. DHA is involved in multiple functions in the human body where it exerts a central role in the physiological and normal development of the individual from the embryonic stage onward. Obtaining high levels of DHA is critical during pregnancy and dur- ing the first year of life in humans because it is essential for the formation and function of the nervous system and vision. For more information visit Clinical Study Shows AstaReal Astaxanthin Effective in Reducing Physical and Mental Fatigue new study published in the Journal of Clinical Therapeutics & Medicines has demonstrated that AstaReal (New Jersey) astaxanthin was simultaneously effective against both mental and physical fatigue. AstaReal Group conducted the study. This is believed to be the first clinical trial demonstrating that a nutraceutical ingredient has properties effective against both physical and mental fatigue. Dr. Robert Corish AstaReal s global medical advisor explained Fatigue is the most common complaint heard by physicians today and in my experience this is the first time that a natural ingredient has been shown to improve this common condition. Commenting about this new clinical trial Dr. Corish remarked The results show that AstaReal astaxanthin suppresses and fights both mental and physical fatigue and improves performance. For more information call (877) 227-8287 or visit A Go to kml for info about this advertiser November December 2016 22 Nutrition Industry Executive AHPAUpdate Leading Industry Association Speaks Directly to Nutrition Industry Executive Readers Experts Urge Industry to Use Caution When Using DNA Analysis Community accepted methodological validation of DNA NGS is likely several years away. C ompanies should proceed with caution when considering the use of DNA analysis to verify the identity of herbal and botanical ingredients. This is the message from leading DNA experts who recently published a paper that the American Herbal Products Association (AHPA) has posted to its website. The article A Caution to Industry and Regulators - Incidental DNA Fragments may be misinterpreted using Next Generation Sequencing (NGS) is authored by Dr. Steven Newmaster professor botany & genetics genomics at the University of Guelph Dr. Subramanyam Ragupathy senior scientist NHP molecular diagnostics at the Biodiversity Institute of Ontario and Dr. Robert Hanner chief technology officer (CTO) at TRU-ID Ltd. As the industry struggles to make use of DNA testing amid widely divergent claims and opinions on the readiness of this new technology to enter the pantheon of reliable testing methods these experts examination of the strengths and limitations adds an important component to the conversation. In the paper the authors explore the benefits and limitations of NGS one type of DNA analysis. NGS is a powerful research tool as it is very useful for detecting multiple sources of DNA in a single analysis a quality that can be useful in answering certain research questions the authors wrote. But the published literature indicates there are considerable problems with NGS that present an immediate impediment to generating scientifically valid test results as are necessary for commercial use of this tool to verify herbal ingredient identity and that therefore require additional research. One of the issues with NGS that is highlighted by the paper is incidental DNA fragments that can result in conclusions that are irrelevant at best and potentially misleading. The authors wrote that NGS results may indicate presence of species in a sample due only to detection of incidental DNA and may also over-estimate the amounts of incidental DNA. This can result in inaccurate conclusions that are due to a trace amount of an inconsequential taxon that has no real relevance to the analysis or underlying research. During the past year we have heeding the experts advice and proresponded to industry concerns that ceeding with caution. Waiting for the commercial NGS test results are reportlibraries and pipelines to be developed ing confusing results including considervalidated and published in peerable weed species in samples the reviewed sciauthors noted. This is not surprising entific journals since farm operations encounter considwill help erable amounts of incidental DNA from ensure the agricultural weeds in every field NGS is industry ultiso sensitive it is possible it is detecting mately benefits very small numbers of DNA fragments from the from weeds on a farm that are in only appropriate negligible amounts in the harvested application of crop. this technoloThe paper concluded that NGS is a gy. NIE promising technology that will only be commercially available for the food supplement and natural health product Michael McGuffin (NHP) industries once the libraries and President and Board of Trustees pipelines have been developed validated and published in peer-reviewed sciAmerican Herbal Products entific journals. The authors team is conAssociation (AHPA) tributing to the necessary research and development initiatives for NHPs but community accepted methodological validation of such methods is still likely to be several years away. The herbal products industry has a long history of innovating new methods and tools to ensure high-quality herbal and botanical ingredients and DNA analysis is emerging a promising new tool. However the industry must proceed with caution. Like any new tool it is only useful if it is properly understood and used appropriately by qualified and experienced experts. The industry has already experienced some of the problems created by the improper application of DNA analysis. Future problems Go to somalabs can be avoided by Nutrition Industry Executive 23 November December 2016 AssociationNews NPA Recognizes Outstanding Contributions to the Natural Products Industry T he Natural Products Association (NPA) recently announced winners of the 23rd Annual NPA Awards honoring outstanding individuals in government and businesses that have made valuable contributions to the success of the natural products industry. The awards were handed out in September during Natural Products Expo East in Baltimore MD. The Natural Products Association is once again honored to celebrate the industry s most prominent leaders said Daniel Fabricant PhD NPA executive director and CEO. For more than two decades NPA has honored the best and brightest in their field and this year s winners build upon that proud tradition. We look forward to continuing to support and collaborate with leaders in government and business who strive to further the growth of and access to natural products for consumers. The winners of the 2016 NPA Awards include supplement-focused Administrative Order 346 on the list of requirements the Task Force must address in its first report to Congress due by Dec. 31 2016. The order would place new and unnecessary regulations on the natural products industry in Puerto Rico and Rep. Zinke s provision would force the Task Force to consider the economic effect of Administrative Order No. 346 on the natural products industry. Lifetime Achievement Award Rep. Matt Salmon (R-AZ) The Lifetime Achievement Award is bestowed to a pioneer in the natural products industry. Rep. Salmon retired from Congress this year leaving behind a storied legacy as a defender and pioneer of the natural products industry. In one of his final Congressional battles Rep. Salmon has spoken out against the attempt to over-regulate natural products and dietary supplements in Puerto Rico. Rep. Salmon has also been a crucial defender of the natural products industry as a member of the Congressional Dietary Supplement Caucus. Industry Champion Award Jeff Novitzky The Industry Champion Award recognizes individuals who have made notable contributions to the natural products industry above and beyond commercial success. Novitzky first gained renown in 2003 while working as an IRS agent in the San Francisco CA Bay Area where he uncovered the BALCO doping conspiracy. Later Novitzky moved to the FDA (U.S. Food and Drug Administration) where he helped drive the government probes that brought down Roger Clemens and Lance Armstrong. Novitzky has now become the vice president of athlete health and performance for the Ultimate Fighting Championships the world s largest promoter of mixed martial arts. Socially Responsible Retailer Award Southtown Health Foods The Socially Responsible Retailer Award recognizes an NPA member company that excels with integrating social responsibility in multiple aspects of their businesses such as volunteerism education employee empowerment environment and health. Southtown Health Foods Chicago IL is a family-owned business founded in 1948 and their mantra has always been that family goes beyond next of kin and is about the entire neighborhood. They see their role in the community to be the one store where people can come to get healthy food products nutritional supplements and the knowledge needed to make the best choices when it comes to their personal health and well-being. For more information visit awards. President s Award Rep. Ryan Zinke (R-MO) The President s Award recognizes an individual who has made long-term contributions or a one-time significant impact to the natural products industry. In May 2016 Rep. Zinke successfully placed a provision into the Puerto Rico Oversight Management and Economic Stability Act which put the dietary ConditionSpecific (Continued from page 8) Industry leaders agree the main problem with botanical ingredients is quality. While we all want quality ingredients reality is that the existing regulations aren t fit when it comes to botanicals sourcing said Raz. As all botanicals sourcing starts at the farm vertical integration is almost the only way to assure we really know where our ingredients are coming from. When some ingredients are being traded and distributed across several continents tracking all the way to the soil becomes a real challenge. These are the same hurdles the industry has been facing for a long time added Dolnick. Adulteration in the extracts category is rampant. Manufacturers only interested in getting the least expensive material are feeding 24 Nutrition Industry Executive into the adulteration problem. It must become a red flag if a company can purchase Ginkgo biloba extract for 50 kg or bilberry extract for 180 kg. Manufacturers certainly need to watch their bottom line but the first priority should be using only high-quality ingredients. TR Nutritionals addresses the issue of adulteration by working with only the finest botanical extracts manufacturers Dolnick said. We keep up on the proper test methods and inform our customers about what testing they should be doing. If the industry as a whole does this we can weed out the manufacturers that are adulterating their products and the suppliers that are selling them. Kreienbrink pointed out another issue with botanicals is poor flavors but those can be masked with natural fruit flavors. Ultimately he concluded in order to meet the current as well as future demands for plant-based nutritional supplements formulators need to continually incorporate creative regionally and culturally diverse botanical ingredients. Clean clear transparent botanical ingredients for the nutritional industry are not only a hot trend they are here to stay NIE FORMOREINFORMATION BI Nutraceuticals (310) 669-2100 Lycored (973) 672-2160 Maypro Proprietary Branded Ingredients Group (914) 251-0701 TR Nutritionals (404) 935-5761 November December 2016 ScienceUpdate Vitamin E May Prevent Pneumonia in Nonsmoking Elderly Men dministration of 50 mg daily of vitamin E decreased the risk of pneumonia in elderly male smokers by 72 percent after they quit smoking according to a paper published in Clinical Interventions in Aging. Dr. Harri Hemil University of Helsinki Finland studied whether vitamin E supplementation might influence the risk of communityacquired pneumonia. He analyzed the data of the randomized trial (AlphaTocopherol Beta-Carotene Cancer Prevention [ATBC] Study) which was conducted in Finland between 19851993 and included male smokers aged from 50 to 69 years. The age when the participant had started to smoke significantly modified the effect of vitamin E on pneumonia. Vitamin E decreased the risk of pneumonia by 35 percent in 7 469 participants who had started smoking at a later age at 21 years or older whereas the vitamin had no apparent effect on pneumonia for those who had started to smoke at a younger age. A Among the 7 469 participants who started to smoke at a later age vitamin E supplementation reduced the incidence of pneumonia by 69 percent in a subgroup of 2 216 light smokers who exercised in their leisure time. In this subgroup vitamin E prevented pneumonia in 12.9 percent of the participants by the time they reached the age of 74 years which corresponds to one in eight getting a benefit from the vitamin. The vitamin did not have a significant effect on participants who smoked heavily or had not been taking exercise. One-third of the 7 469 participants quit smoking for a period and 27 of them got pneumonia. These 27 cases of pneumonia can be used to esti- mate the effect of vitamin E on currently nonsmoking males. The incidence of pneumonia was 72 percent lower in the vitamin E participants who had quit smoking and this benefit from vitamin E was also seen among those who smoked heavily or did not exercise. Although the evidence of benefit from vitamin E against communityacquired pneumonia in elderly males is strong in this analysis the overall findings about vitamin E have been complex. Furthermore the participants of the ATBC Study had mostly been born in the 1920s and 1930s and lived through the World War II years. Thus even though the 72 percent decrease in pneumonia risk with vitamin E in ATBC participants who quit smoking may be a real effect it should not be generalized to current elderly males in Western countries. Further research on vitamin E in nonsmoking elderly males is warranted Hemil stated. For more information visit en. Vitamin B Levels During Pregnancy Linked to Eczema Risk in Child nfants whose mothers had a higher level of a particular type of vitamin B during pregnancy have a lower risk of eczema at age 12 months a new Southampton study has shown. The study from the Medical Research Council Lifecourse Epidemiology Unit University of Southampton U.K. is the first to link maternal serum levels of nicotinamide a naturally occurring vitamin and related metabolites to the risk of atopic eczema in the child. The researchers believe the findings support the concept that eczema partly originates as a baby develops in the womb and could reveal ways of reducing the risk of the skin condition. Nicotinamide cream has been used in the treatment of eczema but the link between the mother s levels of nicotinamide during pregnancy and the offspring s risk of atopic eczema has not been previously studied said Dr. Sarah El-Heis the study s lead researcher from the University of Southampton. The findings point to potentially modifiable I influences on this common and distressing condition. The research published in Clinical and Experimental Allergy assessed the amount of nicotinamide and related tryptophan metabolites during pregnancy in 497 women that took part in the Southampton Women s Survey. The rates of eczema in their children at ages 6 and 12 months were studied. Results showed that offspring of mothers with higher levels of nicotinamide had a 30 percent lower chance of developing atopic eczema at 12 months. There was an even stronger association with higher levels of anthranilic acid a tryptophan metabolite. Nicotinamide can improve the overall structure moisture and elasticity of skin and therefore could potentially alter the disease processes associated with eczema the researchers say. The study showed a gradual association between higher maternal nicotinamide and anthranilic acid levels and a lower risk of atopic eczema suggesting that the development of eczema is not simply prevented by the presence of these nutrients. Professor Keith Godfrey director of the NIHR Southampton Biomedical Research Centre in Nutrition added More research is needed to investigate this interesting association but the findings are further evidence of the potential benefits of eating a healthy balanced diet during pregnancy. For more information visit November December 2016 Nutrition Industry Executive 25 SupplySideWestWrapUp SupplySide West Trade Show Celebrates 20th Year early 15 000 suppliers and buyers were in attendance October 4-8 at Mandalay Bay in Las Vegas NV for this year s SupplySide West event. Attendees included those from the dietary supplement functional food beverage personal care and sports nutrition marketplaces. Show highlights included A 9 percent increase in total participation from 2015 with a grand total of nearly 15 000 participants from very diverse geographic regions--50 states eight Canadian provinces and 64 countries More than 1 200 companies exhibiting on the show floor C-level executives buyers and other professionals from the following companies were in attendance Abbott Nutrition AdvoCare Amway Nutrilite Aveda Bausch & Lomb Inc. Bayer HealthCare Bil Jac Foods Church & Dwight Clif Bar & Co. Dannon Co. Dr. Pepper Snapple Group GNC GlaxoSmithKline Hain Celestial Group Herbalife International Isagenix Kellogg Co. Mars Petcare Mead Johnson Nutrition Medifast Inc. NBTY Nestle Purina Niagara Bottling PepsiCo Perrigo Nutritionals LLC Procter & Gamble Quest Nutrition Reckitt Benckiser Shaklee Corp. The Clorox Company Twinlab Corp. USANA Health Sciences Whole Foods Market WhiteWave Foods and more. Since the first SupplySide West show 20 years ago our mission has been to support the growth and prosperity of our industry said Jon Benninger vice president of the Global Health & Nutrition Network for Informa Exhibitions. That is a role and responsibility we embrace and take very seriously. N On the Show Floor SupplySide West participants were similarly enthusiastic about this year s outing. SupplySide seems to be getting better and better each year with its thoughtful mix of education key industry leaders and line-up of ingredient suppliers for foods supplements and cosmetics said Kantha Shelke PhD with Illinois-based Corvus Blue. Alan Rillorta director of protein and branded ingredient sales with Californiabased AIDP said the company has exhibited at the trade show for 18 years. Showcasing its full line of science-based branded and specialty ingredients for the 26 Nutrition Industry Executive nutritional and food industries Rillorta said this year s show was great. We were able to set up many meetings with customers and ingredient partners both during the show and the days around the show. Traffic by our booth remained busy both days. Researched based ingredients have attracted visitors. Many customers having heard of these products finally have a chance to have a face-to-face discussion. We have gathered a Cara Welch lot of leads to follow up. Bethany Davis director of regulatory affairs with FoodState Inc. in New Hampshire added SupplySide West offers essential education and insights and hosts top-notch suppliers and brands. But maybe even more importantly it offers opportunities for connections and networking. Everyone attends this conference and with ample opportunities to meet and mingle with industry leaders it pays for itself and then some. The 2016 edition of SupplySide West was outstanding said Michael Derrington senior director of sales-- dietary supplements probiotics protein at DuPont Nutrition & Health in Missouri. The traffic and customer interface was amazing not only for our company but it also appeared to be for each company on the show floor. The major advantage of this event is that it allows for companies to meet with nearly every single one of their top partners over a two- to three-day period where you can qualify new mutually beneficial opportunities that would take months to cover otherwise. I can also experience seeing and communicating with people I have known for many Loren Israelsen years as an added bonus. SupplySide West 2016 was probably the most productive two to three days we will have in the course of a year. Education SupplySide West is also known for a range of conference programming this year s event revamped the format to offer three-hour workshops two-hour panel discussions a full-day summit on the clean label market opportunity and an opening presentation on FDA (U.S. Food and Drug Administration) issues. In her featured speaker session FDA s Cara Welch PhD senior advisor Office of Dietary Supplement Programs addressed concerns with the new dietary ingredient (NDI) draft guidance GMP (good manufacturing practice) compliance and ingredients including vinpocetine and cannabidiol (CBD). Welch noted that the program s priorities are to protect consumers ensure product integrity and provide education especially for consumers and health care providers additionally she stressed the importance of keeping a big picture approach. Participants had the opportunity to dive into specific areas of interest ranging from regulatory topics such as claims substantiation to key ingredients such as probiotics and omega-3s health issues including weight management and formulation considerations such as sweetener selection or gluten-free product development. At the GMOs Today s Challenges Tomorrow s Opportunities panel discussion for instance panelist Loren Israelsen president of the United Natural Products Alliance (UNPA) noted that companies are beginning to refer to GMOs (genetically modified organisms) as genetically engineered or bio engineered --this is in an effort to focus less on GMO more on engineering. Attorney Adam Fox managing partner at Squire Patton Boggs dove into the legal perspective of the matter alluding to Vermont s GMO labeling law including people s criticisms of QR (quick response) codes and technological challenges. He also spoke of tension between the U.S Department of Agriculture (USDA) and FDA with respect to food labeling power and authority. The 2016 SupplySide West Education Program proved to be among the best yet said John Helfrick director BASF Human Nutrition North America. This was my first visit to a SupplySide West show and it was fascinating to hear firsthand about the challenges as well as the November December 2016 opportunities colleagues face each day. One thing rings true from these varied conversations timely and credible education is key to our success. It s the content quality and relevance to critical topics impacting our industry that drive BASF to continuously renew sponsorship of the Education Program. Attendees could also seek learning and networking opportunities in the expo hall at SupplySide Central. Offering a variety of interactive quick-paced programming designed to delve into some of the hot topics facing the industry SupplySide Central featured topics from the Ingredient Launchpad where exhibitors highlighted their new products to the Fifth Annual CPG Editor s Choice Awards where SupplySide West recognized the most innovative product launches in supplements and food and beverage. In today s dynamic health and nutrition market getting the insights necessary to drive product development and launch is critical to market success said Heather Granato vice president of content for Informa s Global Health & Nutrition Network. SupplySide West offers thematically based content with information that can be applied immediately whether in the boardroom the lab or the manufacturing plant. For First Timers A variety of show features and networking opportunities also allowed show participants to make key industry connections. In its second year the First Time Attendee Reception brought together first-time show participants with industry rock stars to share insights on how to make the most of the show. In the Expo Hall special pavilions targeted important ingredient sectors--omega-3s developed with the Global Organization for EPA and DHA Omega-3 (GOED) and developed with the International Probiotics Association (IPA). Many industry associations also maximized their exposure with membership meetings and education programming including the Botanical Congress from the American Herbal Products Association (AHPA) and actively supported SupplySide s Compliance Program an initiative in its fifth year dedicated to ensuring exhibitors are compliant with appropriate regulatory standards. SupplySide West and Informa Exhibitions capped off its successful show with a 31 870 donation to Vitamin Angels. This year s SupplySide Cares program donated 5 from every paid attendee registration to support this impactful non-profit that is dedicated to bringing vitamin supplementation to atrisk populations in need--specifically pregnant women new mothers and children under 5. Next Year In 2017 Ingredient Marketplace will be held April 18 to 20 at Orlando World Center Marriott in Florida. The SupplySide West show will be held September 26 to 30 at Mandalay Bay in Las Vegas NV. For more information visit THE NUTRITION INDUSTRY S NEWS & INFORMATION RESOURCE NIE s Upcoming Issue Highlights Jan. Feb. 12 15 16 ad closing Industry Forecast Engredea at Expo East Show Issue March 2 3 17 ad closing 2017 Supplier Sourcebook April 3 17 17 ad closing Global Supply Chain Management Ingredient Marketplace Show Issue Our 2017 Media Planner Is Available At 2017-Media-Planner Contact One of Our Ad Specialists Today Russ Fields at 732-432-9600 ext. 102 or e-Mail RussF Gary Pfaff at 732-432-9600 ext. 103 or e-Mail GaryP November December 2016 Nutrition Industry Executive 27 Consumers are taking a proactive role to combat high blood sugar--which includes taking supplements. By Janet Poveromo W ith 28 million people in the United States suffering from diabetes as well as another 80 million with pre-diabetes the concern with blood sugar has become a health care priority. There are many factors which can contribute to rises in blood glucose for those with type 2 diabetes such as metabolic syndrome weight gain dehydration lack of sleep hormonal irregularities insufficient exercise medication interactions and stress said Carol May president of Arizonabased Wisdom Natural Brands producer of stevia products. However the daily diet remains the primary resource for change for the majority of people with this disease. 28 Nutrition Industry Executive Beyond the U.S. according to the International Diabetes Federation (IDF) more than 415 million people worldwide have elevated blood sugar levels and are diagnosed with diabetes (as of 2015). It is predicted that by 2040 this number will be more than 640 million. The unfortunate situation is that more than 50 percent remain undiagnosed indicating the general population could benefit from natural supplements to support healthy blood sugar levels said Shaheen Majeed marketing director with Sabinsa in New Jersey. There is an exponential demand for evidence based ingredients and products that are safe and effective. Increased efforts are needed to educate diabetes patients on the potential benefits and values of other nutraceutical ingredients backed by science to address their diabetes status and related conditions added Bryan See regional product manager with New Jersey-based ExcelVite Inc. He pointed to a ground-breaking economic report by Frost & Sullivan (commissioned by the Council for Responsible Nutrition [CRN] Foundation) which stated that chromium picolinate dietary supplements use to address diabetes-attributed coronary heart disease costs could lead to a potential cost saving of U.S. 970 million per year (or U.S. 7.80 billion savings from 2013 to 2020). This is a significant saving given that there is only up to 1 percent of diabetic adults over the age of November December 2016 55 being regular users of chromium picolinate not to mention that this is only one ingredient that the report has focused on. Consumer Knowledge General awareness among consumers that herbs and supplements can support good health and minimize the likelihood of developing many conditions has increased said Majeed. Consumers are more likely to trust those products with proven clinical safety and efficacy. High-quality clinically proven ingredients are preferred for any serious health condition including blood sugar management. A holistic approach such as improved insulin sensitivity repair of damaged pancreatic cells increased insulin production and so on is ideal and possible with the use of selected natural ingredients. See agreed noting that some consumers are becoming increasingly aware of the need to take preventative action to manage their health by taking the necessary steps to screen and monitor blood sugar levels and making dietary and lifestyle changes to prevent diabetes. Furthermore instead of just looking for a dietary supplement product or ingredient to address blood sugar control these consumers are becoming savvy enough to understand that they need to also address risk factors that might worsen their health if they have diabetes--such as cardiovascular diseases. This leads to a growing marketplace for multiple products ingredients to address overall health being in the concept of preventive health care. Annie Eng CEO of Florida-based HP Ingredients said that from the company s perspective ingredients tend to evolve when regular scientific exploration reveals mechanism(s) of action. From this point experienced researchers can design efficacy studies and those that have positive outcomes then become very attractive to brand marketers retailers and consumers. Our ingredient in this category has been shown to support healthy blood sugar via working in the metabolic and NAFLD (non-alcoholic fatty liver disease) pathways. HP Ingredients BERGAMONTE BFP fits this bill Eng added. This natural ingredient contains bioactive compounds of citrus bergamia risso juice and albedo extract standardized to 38 percent polyphenolic flavonoids consisting of naringin neohesperidin neoeriocitrin 1 percent melitidine and 2 percent brutelidine. These flavonoids are clinically proven to help maintain healthy blood glucose levels and healthy cholesterol profiles. When these numbers are elevated the medical community considers it as potential presence of metabolic syndrome. acknowledge the benefit of blood glucose management as relevant for human health. Thus proven efficacy and safety of a product is essential to gain consumers attention and trust as well as to overcome regulatory hurdles. In all Portusana with its demonstrated clinical efficacy is the perfect ingredient for innovative applications in the area of blood glucose management. Evolution of Ingredients Aparna Kalidindi PharmD BCPS technical sales and marketing manager with Natreon Inc. in New Jersey said there are a wide range of applications with ingredients being used in this category. For example ingredients such as chromium gymnema sylvestre and alpha lipoic acid are beneficial for blood glucose control but are also used for cardiovascular health as well especially in addressing elevated lipid levels. Virginie Codran product manager with Frutarom Health in Belgium noted that plant derivatives with supported hypoglycemic properties have been used in folk medicine and traditional healing systems around the world. When it comes to health and prevention consumers are looking for natural solutions as alternatives to prescription medications she said. Thus functional foods and dietary supplements positioned to address issues of blood sugar management and issues of insulin resistance represent mass market opportunities. A recent Health Focus Survey reported that more than one third of primary grocery shoppers think that helps maintain healthy blood sugar levels is a very extremely important claim and 60 percent showed interest in low glycemic index foods. High blood sugar is not only a concern for those with pre-diabetes or diabetes she added. Healthy individuals register the diabetes epidemic and want to take natural preventive measures. However although the blood glucose management market shows great potential there are also some challenges. On the one hand consumers understanding of glycaemia management is still quite limited and additional communication efforts are needed to increase public awareness and understanding. On the other hand the market is highly regulated. Nonetheless regulatory bodies A Range of Approaches for Management As noted earlier a holistic approach is preferred in the management of lifestyle-related health conditions. For blood sugar level management in particular it is not usually in isolation but associated with other conditions such as high cholesterol obesity and conditions that sum up to metabolic syndrome. Ingredients such as Curcumin C3 Complex have not only been evaluated for their role in managing sugar levels but in all other parameters associated with metabolic syndrome Majeed said. See also noted that formulators are using bio-enhanced active ingredients that have increased absorption into plasma (bioavailability). In addition manufacturers are beginning to formulate and develop functional food and beverage for the convenience aspects. That may come with some disadvantages according to Mitch Skop senior director of new product development with Pharmachem Laboratories in New Jersey. Americans simply adore sweets and the advent of stevia and other natural non-nutritives as natural sweetening agents in packaged products and for baking should hopefully have a long-lasting and powerful effect on helping millions of people to support healthy blood sugar response he explained. That said carbohydrates (the bad or simple kind) still remain a ubiquitous aggravator of unhealthy blood sugar response--that when unchecked for the long-term dramatically increases risk of developing type 2 diabetes. Overall we see primarily tablets and capsules (pill form) because to provide effective support for healthy blood sugar response anything in food form may pose a contradiction especially if it is not sweetened with such ingredients as stevia. And too there are supplements that have been Nutrition Industry Executive 29 November December 2016 clinically shown to do double-duty assist in weight reduction and assist in promoting healthier blood sugar response similar to how omega-3 EFAs (essential fatty acids) promote healthy cardiovascular function and support healthy brain structure and cognitive abilities. Innovations Health Studies It is a rare person who can willfully and totally give up the type of carbs found in breads pasta and potatoes Skop said adding that favorite traditional comfort foods all contain one or more of these. For good reason he said there is indeed a feel good effect in such indulgences. There is a side effect to this indulgence the unhealthy flood of blood sugar the sharp spike. Therefore to assist in enjoying that feel good food we have created Phase 2 DietSpice which provides a specific health advantage through a functional ingredient in a form that is a seasoning for a wide variety of food. DietSpice adds popular flavors-- Italian Asian Butter & Spice and Cinnamon Sweetener. Prenulin also from Pharmachem is a combination formula of L-arabinose and high-quality forms of chromium. As such Prenulin provides the consumer with both the glucose absorption benefits of L-arabinose and the insulin control capability of chromium. Further brand marketers may choose Prenulin with Pharmachem s FoodBound Chromium a unique patented form of pre-chelation and also with Chromax chromium picolinate (Nutrition 21). This form is GRAS (generally recognized as safe) for nutritional bars and beverages widening the options of delivery and use for Prenulin. Clinical studies that emphasize the safety and efficacy of any ingredient are what suppliers and manufacturers are looking for. Further any formulation guidelines details on the physical and chemical nature of the ingredient and its compatibility with other ingredients are some of the additional features in which they may be interested. 30 Nutrition Industry Executive Pharmachem s Phase 2 is known to help reduce digestible carbs in starchrich foods and has been clinically shown to reduce the digestion and absorption of carbohydrates by up to 66 percent. Skop noted that a review of more than a dozen studies published in the Nutrition Journal concluded that Phase 2 Carb Controller has the potential to not only induce weight loss but to reduce spikes in blood sugar caused by carbohydrates. In the study co-author Jay Udani MD CEO of Medicus Research explained Phase 2 Carb Controller has demonstrated the ability to cause weight loss with doses of 500 to 3 000 mg per day in either a single dose or in divided doses. It also has the ability to reduce the post-prandial spike in blood glucose levels (Udani J. Nut J 2011). Clinical studies that emphasize the safety and efficacy of any ingredient are what suppliers and manufacturers are looking for. Two double-blind placebo-controlled studies were conducted to examine the effects of Prenulin on circulating glucose and insulin responses to sucrose challenge. In both studies consumption of Prenulin was shown to significantly lower both circulating glucose and insulin levels after consumption of a 70-gram sucrose challenge compared to placebo. (Kaats et al. Nut J 2011 10 42). At Frutarom Codran pointed to two studies published in 2016. Pruslane Extract and glucose homeostasis in adults with type 2 diabetes is a double-blinded placebo controlled clinical trial designed to evaluate the efficacy and safety of Purslane extract in improving glucose control blood pressure and lipid profile. The second study Biomolecular characterization of putative antidiabetic herbal extracts aims to investigate the GLUT4 translocation induction capacity of plant extracts. Both showed very promising results for purslane extracts. Kalidindi explained that Natreon s Crominex3 used for blood glucose management and more is a trivalent chromium supplement prepared by complexing Chromium III with two natural products Phyllanthus emblica (Natreon s Capros) and shilajit (Natreon s PrimaVie Purified Shilajit). This complex minimizes the conversion of trivalent chromium to toxic hexavalent chromium and it also increases bioavailability. Studies have shown that Crominex3 is synergistic to glipizide and metformin in decreasing the fasting blood glucose levels post-prandial blood glucose levels HbA1c hsCRP and urinary microalbumin levels in type 2 diabetics (this study has been published). Two recent clinical studies in type 2 diabetics and pre-metabolic syndrome subjects have shown that Crominex3 is more efficacious than the other branded chromium products in the market in managing blood glucose levels and also in improving endothelial function lipid profile and hsCRP levels. These studies are currently pending publication. In addition Crominex3 is very economical with each 400 mcg dose costing less than one penny per day. Safety and toxicology studies have been completed in the USA and prove Crominex3 to be a safe chromium supplement. At Sabinsa a recent study on the role of Curcumin C3 Complex in managing dyslipidemia in metabolic syndrome patients has re-emphasized its potential as one the most important nutraceuticals for general wellness and good health. Patients diagnosed with metabolic syndrome according to the NCEPATPIII criteria who were receiving standard care were assigned to either bioavailable curcuminoids (C3 complex BioPerine 1 000 mg day n 50) or placebo (n 50) for eight weeks. Results revealed that curcuminoids were more effective than placebo in reducing serum LDL-C nonHDL-C total cholesterol triglycerides (Continued on page 47) November December 2016 Despite overhang from iffy research conclusions and attendant mass media frenzies the industry boldly forges ahead with innovative products and new education initiatives. James J. Gormley A s noted in the November December 2015 issue of Nutrition Industry Executive magazine essential fatty acids (EFAs) are among the most popular and broadly used ingredients for supplements and food fortification. This is no surprise of course since aside from traditional use throughout human history the nutritional essentiality of alpha linolenic acid (ALA)--the precursor of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)--was established at the University of Minnesota Medical School in 1929. In 1982 the first reported case of omega-3 deficiency in humans was reported although the foundation for which was laid by earlier examples in infants and adults dating back to 1969. As to studies backing up EFAs an extensive 2015 review of research studies over the last 40 years by Karsten Weylandt and colleagues observed that the animal and in-vitro data have been remarkably consistent in showing health benefits particularly through mechanisms dampening inflammation and prolifera- tion in different tissues which have detailed the protective effects of omega3s in diseases ranging from cardiac arrhythmia and inflammatory conditions including atherosclerosis arthritis and cancer. While EFAs enjoy support by consumers public health agencies and medical bodies omega-3 fats in particular have been challenged over the last several years regarding claims of efficacy and supposed problems with oxidation. Regarding claims in a meta-analysis published in 2012 the authors conclusions that fish oil capsules offered no benefit for heart patients were in turn subsequently questioned by other experts due to the statistical sleight of hand used to arrive at this. As to oxidation a 2015 study from New Zealand alleged that fish oil supplements were found to be heavily oxidized. However the methods of analysis used and conclusions arrived at were refuted by the Global Organization for EPA and DHA Omega-3s (GOED) and the Council for Responsible Nutrition (CRN) in a white paper issued in November 2015. According to the white paper A number of consumer groups organizations that issue product quality seals and academic groups have published data on levels of oxidation in omega-3 oils. The GOED-CRN paper concluded Overall this data shows that commercially available omega-3 supplements are low in oxidation. Omegas A Question of Balance Diets of our Paleolithic ancestors and turn-of-the-century Greelandic Inuit boasted a super-healthy ratio of 1 1 omega-6 seed to omega-3 fats whereas the standard Western diet today can range to a ratio of 20 1. How did we get here and can we get back to such a diet Becky Wright marketing and communications director for Norway-based Aker BioMarine AS believes that the imbalance is a nutritional problem across the world. Our bodies only need a small amount of omega-6 fats to support their role in the body making it crucial that we balance them with omega-3s noted Wright. We can actually put our bodies at risk of Nutrition Industry Executive 31 November December 2016 cardiovascular and inflammatory issues if we consume too much omega-6s and not enough omega-3s--in fact omega-3 deficiency is a growing issue affecting the population across the globe. Hugh Welsh president of DSM North America in New Jersey agreed that omega-6 overconsumption is the culprit. In recent years there has been a massive increase in the consumption of omega-6 oils primarily from soybean and corn oil because of their availability and low cost--this increased consumption has shifted the balance of omega-6 to omega-3 fatty acids in our diets Welsh pointed out. Because linoleic acid (LA) an omega6 fatty acid and alpha-linolenic acid (ALA) an omega-3 fatty acid utilize the same enzymes very large intakes of omega-6 create competition Welsh continued. Enough competition to change the flux of omega-3 and omega6 fatty acids through these pathways and the different number of double bonds in these fatty acids changes the shape (and inflammatory activity) of the metabolites. Welsh noted that the leukotrienes thromboxanes prostaglandins and other metabolites created from omega-6 fatty acids are more pro-inflammatory than are those derived from omega-3 fatty acids. John Minatelli senior vice president of Florida-based Valensa International said The ideal ratio of membrane bound omega-6 to omega-3 dietary fat is generally recognized today to be 4 1 favoring a slightly elevated membrane bound concentration of arachidonic acid which is incorporated into all cellular membranes bound to phospholipids. The problem noted Minatelli truly is the imbalance and how that impacts inflammation in the body. Inflammation is an integral part of the normal host response to infection or injury however when omega-6 to omega-3 ratios are excessive production of extremely potent arachidonic acid derived proinflammatory cytokines--also referred to as inflammatory prostaglandins thromboxanes leukotrienes and adhesion molecules--are suspected to increase the risk of developing a chronic disease state. This is why the American diet which is very rich in vegetable oil-based linoleic acid (principally from soy and corn oils) 32 Nutrition Industry Executive has been associated with metabolic syndrome diabetes excessive heart disease and other conditions characterized by a chronic pro-inflammatory state Minatelli added. Minatelli also pointed out that unless there is an adequate and balancing intake of the anti-inflammatory omega-3 essential fatty acids--either as ALA from seeds or EPA and DHA from fish oils getting a handle on the chronic proinflammatory American diet would be nigh near impossible to achieve. Add to this the amount of processed food Americans eat which has been stripped of natural antioxidants and other healthy ingredients and you have a prescription for an unhealthy diet Minatelli said. The Mediterranean diet on the other hand is an excellent example of a balanced essential fatty acid diet since olive oil which is essentially devoid of LA and which includes grains already delivering a 1 1 mixture of LA and ALA and also more dietary fish which are abundant in EPA and DHA all leading to a significant reduction in heart disease mortality according to Minatelli. A Marine Story Now that we have looked at what fats need to be decreased what EFAs should consumers seek out What about the relative nutritional benefits of krill cod-liver conventional DHA EPA extracts perilla chia and flax oils Not all omega-3s are created equal observed Aker BioMarine s Wright. There are many benefits associated with EPA and DHA the long-chain omega-3 fatty acids found in Superba Krill Oil and other marine omega-3 options. Added Wright With krill in particular its fatty acids are largely bound to phospholipids which are integral to the body s cells and cell membranes--due to this biological advantage our bodies immediately recognize phospholipidbound omega-3s and incorporate them into the cells feeding the places that need them the most including the heart brain and joints. Other omega-3 sources specifically those in triglyceride form must go through a conversion process before they can be taken up by our cells and used by our bodies. While its largest massmarket product FlexPro MD employs among other active ingredients krill oil which delivers phospholipid-bound EPA and DHA Valensa has been involved in supercritical CO2 extraction of seed oils (Verilla Perilla seed oil and ChiaGold Tresalbio chia seed oils) that are rich in ALA in an effort to bring according to the company high quality stabilized high ratio ALA LA oils to the marketplace. Our reasoning is simple observed Valensa s Minatelli. Let s fight the excessive American dietary consumption of LA with stable seed oils rich in ALA--a more recent development is the company s emerging algae-based production of oils rich in glycolipid- and phospholipidbound EPA and DHA which would be renewable sources of these health-critical fatty acids rather than relying on fish or krill-oil sourcing. Verilla Perilla seed oil has an ALA LA ratio of 6 1 representing one of the highest ALA LA seed oil contents on the planet and it offers provides unprecedented room temperature shelf stability over expeller-pressed oils Minatelli said. The expeller-pressed oils while they have a favorable 3 1 ratio of ALA LA are terribly unstable and without refinement have a rather sharp grassy taste--this issue was easily overcome by partial fractionation of the CO2 extract during the extraction and separation process. Valensa uses a patented Deep Extract process that additionally extracts other phytonutrients that will increase the health benefits functionality and stability of the omega-3 oils said Minatelli. Further we also stabilize the omega-3 oils like chia seed oil and Perilla seed oil with our O2B botanical stabilization package which increases both shelf space and pantry life of these superior oils. We believe that each product has its own positioning in the marketplace and we continue to educate our customers and consumers on health benefits of omega-3s Minatelli added. For example Verilla Perilla seed oil has a better omega 3 omega 6 ratio than do chia seed oil and flax seed oil. However flax and chia enjoy better consumer awareness. According to Aker BioMarine using newly acquired technology called Flexitech the company has launched its first krill oil concentrate called Superba Boost Caps the product contains significantly more phospholipids and omega-3s compared to the previous generation of Superba Krill Oil. November December 2016 Quality Is As Quality Does With EFAs as much or moreso than any other super-category quality is paramount and the companies we spoke to are making significant investments in order to deliver on this mantra. DSM for example has invested in a new process technology called 3C technology. This radically efficient process technology delivers highly-concentrated (up to 85 percent) and customizable combinations of EPA and DHA for both pharmaceutical and dietary supplement applications while providing peace of mind through a consistent supply chain pointed out Tobe Cohen vice president of DSM Human Nutrition. MEG-3 Ultra the first new [DSM] product line produced with 3C Technology is next generation ultrapure high potency EPA plus DHA combinations with greater nutritional precision Cohen added. DSM has kicked off the Modern Movement Forward marketing campaign to inspire category change through 3C technology--this new technology truly makes the oversized pills of traditional fish oil with low EPA and DHA omega-3 content a thing of the past. Aker BioMarine AS has also been making investments in its products and process technologies. We developed a new patented technology platform called Flexitech which is helping drive more innovation in the krill market specifically and the omega-3 market overall said Wright. Earlier this year Aker BioMarine launched Superba 2 the next generation of Superba Krill Oil--on the heels of that we recently introduced our first krill oil concentrate called Superba Boost to the U.S. market Superba Boost contains a significantly higher concentration of key actives including phospholipids omega-3s EPA DHA and choline. Minatelli points to product quality as a major differentiator for Valensa. Our ChiaGold and Tresalbio chia seed extract can easily replace the highly unstable expeller pressed flax seed oil consumed in the market today which by the way is merely a byproduct of making linseed oil for furniture finishing due to flax oils terrible instability this is why it is commonly marketed in refrigerated bottles with very limited expiration dates added Minatelli. In terms of recognition We also recently obtained substantial equivalence under EFSA [the European Food Safety Authority] for our ChiaGold chia seed oil in the E.U. Purity and taste are also important factors and some companies are working hard to raise the bar. In terms of taste Aker s new Flexitech platform allows for the removal of the salts in krill oil which can lead to off odors and taste said Wright. The process does not involve any form of high temperature treatment such as molecular distillation nor does it involve the use of other solvents besides ethanol and water it relies solely on low temperature and efficient fractionation methods that remove unwanted salts and other polar constituents. According to DSM s Welsh The top consumer barriers to greater omega-3 supplementation are related to potency purity and taste--DSM adheres to the most stringent quality parameters and exceeds industry standards so that the consumer experience is positive. EFAs The Education Boat is Moving One area of intense category focus recently has been in the area of education given the recent massmedia (mis)reporting on omega-3s it perhaps couldn t come at a better time. Aker BioMarine just launched The Omega-3 Index Project in an effort to bring more awareness to the ramifications of low omega-3 EPA DHA levels said Wright. The project encourages consumers to regularly measure their omega-3 levels using a nutritional tool called the Omega-3 Index Test--it also encourages consumers to know what their options are for increasing their levels specifically omega-3-rich seafood as well as dietary supplements that contain EPA and DHA like krill oil algal oil and fish oil. Aker formed The Omega-3 Index Project in conjunction with Dr. Bill Harris a co-inventor of the Omega-3 Index test. Used to assess cardiovascular and overall health the Omega-3 Index test is geared to help consumers and health practitioners identify correct and maintain healthy levels of omega-3s EPA DHA while reducing the risk of chronic disease. We hope to roll out [the Project] globally in 2017 added Wright. According to a study published in the May 2016 issue of Progress in Lipid Research the low EPA DHA status of consumers globally is staggering and deserves attention--consumers need to know (1) what their omega-3 index level is (2) what their omega-3 index level means and (3) the solutions available to raise their levels should they need to. DSM launched the Know Your campaign at this year s American Academy of Family Physicians (AAFP) Family Medicine Experience (FMX) annual meeting. Know Your recognizes the vital role that health care practitioners play in addressing the vast inadequacy of omega-3 intake among the U.S. population said Welsh. A large and growing body of evidence shows that insufficient levels of omega-3 EPA and DHA may be associated with serious health complications for many Americans said Michael McBurney PhD vice president of science communications and advocacy for DSM Nutritional Products. Know Your is a resource that educates doctors on the dangers associated with omega-3 deficiency and supports omega-3 recommendation to help protect patients from cardiovascular disease and other health risks. NIE Extra Extra To learn more about the Omega-3 Index Project visit FORMOREINFORMATION Aker BioMarine AS DSM North America Valensa International (877) 876-8872 November December 2016 Nutrition Industry Executive 33 MarketingInnovations By Suzanne Shelton and Todd Pauli The Shelton Group rade shows it seems like we ve always just returned from one and now we re already planning for the next one. After many years in the industry they can all become a blur. If you re relatively new to the industry they are still a bit of a mystery. But we can all benefit from occasionally revisiting how we re handling them. Meeting potential customers face-toface is still one of the best ways to quickly form a trusted relationship and have a meaningful conversation that will help you understand the person s needs so you can tailor your sales message accordingly. This holds true if you are a company selling your products from a booth or attending the show to find new products and observe trends or are there to meet with clients and colleagues and scope out new opportunities. T Many of us have a set show route attending the same ones year after year without necessarily exploring the other options. We recently attended the IFT show after having skipped it for a few years and it is now back on our list. And with the recent acquisition of Penton including New Hope by Informa Exhibitions there are likely to be some changes in the usual suspects. attention to company roles when making your decisions. An ingredient buyer may very well be traveling booth to booth in search of a new source whereas a chief science officer may be more open to a conversation during a smaller industry trade event designed specifically for company leadership. Stick to the Script Among the thousands of booths at the trade show the objective for you will undoubtedly be to stand out. And while you ll want to draw attention to your products it s important to make sure you are attracting the right attention. At any large show many of the attendees won t be interested in your product or services so how do your reach the buyer s looking for what you have to offer It starts with the booth itself. Long before you travel to the show the Do I Need to Be Here Both trade shows and event sponsorships are expensive so while in-person meetings are extremely important make sure you are establishing a presence in the right venue. The key to spending your event budget wisely is to make sure you are as targeted as possible. Talk to the show representative to understand who attends and who will likely be walking the aisles. Also pay 34 Nutrition Industry Executive November December 2016 booth graphics will need to be printed. The secret to a great booth is simplicity. Most show attendees aren t interested in reading as they walk the aisles so while it s tempting to print every relevant product benefit study or supporting fact on the booth backdrop stick to a simple clear message about your product or service. If you have done your branding homework you will already know how to boil down your unique selling proposition (USP) into a quick statement that attendees will understand instantly. This message belongs on your booth. Beyond that a few simple callouts and professional attractive graphics that fit your brand will round out the design. A helpful check to ensure you re striking the right balance of copy on your booth is the 10-foot check. Most booth spaces are 10 feet wide and even if you ve sprung for a larger space attendees will rarely keep there eyes trained on one spot as they pass your booth. As you consider a booth design ask yourself if an attendee walking the 10foot length of your booth will understand what you offer after they pass. If not it s time to tighten up the copy. Once an attendee stops at the booth make sure the literature or samples you display clearly support your brand message with a professional cohesive design. Also offer to email a one page PDF containing all the relevant information to a potential customer in case they prefer not to carry your sales materials for the rest of the show. Finally no matter how many company representatives are working the booth be sure to provide each of them with a simple one page summary of the message you want conveyed to show attendees. The summary should include a succinct company overview your USP and key features of the products or services you want to focus on at the show. It s easy to assume everyone working the booth already knows this information but that s usually not the case. The trade show booth is no time to play the telephone game and laugh at the crazy final brand message that gets passed along to a potential customer. Vice episodes it is easy to neglect planning for customer interaction. Two types of booth staffers that won t make your show investment worthwhile 1. The person working the booth sitting down texting and generally not caring what is happening on the show floor. It s no secret that tradeshow booth duty can be a drag. We ve all done it or are still doing it but the more effectively your staff uses the time in the booth the better experience everyone will have and the more productive your investment. Provide specific instructions to your staff about booth etiquette. Instruct them to stand up put smiles on their faces and strike up a few conversations. It makes the time go much faster and they re much more likely to meet potential customers that make the whole effort worthwhile. 2. The person who pulls us from the aisle to give us a speech about their product or blocks our path in the aisle with a leading question about our protein intake. Normal meaningful relationships don t start this way in the real world and we don t believe they should start this way in the trade show world. Instead recommend to your booth staff to just be friendly and attentive. Say hello make eye contact and strike up a conversation involving a normal exchange about your products and their benefits. Beyond the small talk and conversation starters remind them to stick to the one page summary you ve prepared for each of them. Instruct them to scan badges and make notes or get a business card so you can follow-up. In general your staff will meet people and build customer relationships in the same way they might make friends at a party Be kind be a great listener and show genuine interest in the person visiting the booth. If everyone starts with this approach the chance to share product information in an authentic way will come naturally. niques effective booth designs or potential new products. Ask them to take photos and pick up literature and trinkets they admire. Once the team is back home try rewarding everyone s show efforts with a free lunch where each person has the chance to share what inspired them on the show floor. These recap discussions frequently lead to new sales strategies marketing campaigns and booth designs. Beyond the Booth As long as you are there plan to take advantage of the education program. The main industry shows put together well thought out and relevant seminars with speakers chosen for their experience and demonstrated knowledge (with the occasional big sponsors and advertisers thrown in). Once you have a good idea what the sessions are like start thinking about a topic you could propose for the next show s education program which by six months out they are already planning. Some shows have formal topic proposal procedures to follow and they really do choose a large part of their program from speaker ideas. Take advantage of the opportunity to hear what the heads of the trade associations have to say on issues that impact your business. This is often your best resource for what the future is likely to hold and gives you the opportunity to take appropriate action. Most of them are very approachable particularly for members so one-on-one conversations are often easy to arrange. On the PR side most of the trade magazines do show coverage in advance of the show so be sure to email your media list a news release with new product introductions recently completed expansions booth activities and any other related news several weeks in advance. If you re hoping to be in their print versions make that six weeks in advance. If you have new products or studies on your products to talk about request meetings with trade magazine editors to talk about what s new. Be sure to contact them several weeks in advance for this. They ll be booked solid if you wait. Make a point of having real news or developments to talk about so they feel it s a half hour well spent then follow up with them after the show to Use the Show Floor Scheduling enough time for your booth staff to take breaks and walk the trade show floor to keep them energized while working the booth is important but it also instills an additional benefit. The trade show floor full of both competitors and industry brands you admire presents an opportunity for your staff to get informed and inspired. Encourage them to walk the aisles taking notice of great marketing tech- Don t Be That Person After you design the trade show booth fill out the countless order forms for electricity carpet and those white leather and chrome chairs that only exist at trade shows and in old Miami (Continued on page 38) Nutrition Industry Executive 35 November December 2016 FunctionalFoods By Nicholas Saraceno F or years via advertisements and pure word-of-mouth individuals have not only praised the wonders of fiber but how important it is to consume it. Insoluble fiber for instance helps digestive health such as through combatting constipation ( According to studies have also shown that ingesting fiber is associated with a lower body weight. Of course this only begins to scratch the surface on what the substance is capable of as its positives not only attract consumers with different needs and conditions but allows for a promising future in this realm as well. What makes it more appealing is the idea of adding it to functional foods. Benefits Galore Besides the aforementioned facts fiber exists in two variations soluble and insoluble which either dissolve or remain solid when mixed with water. As Hugh Welsh president of DSM North America in New Jersey mentioned a bulk of dietary fibers (fibers derived from plant foods that the body cannot digest) is being utilized in func36 Nutrition Industry Executive tional foods due to the fact that the overall flavor is not compromised. Many isolated or synthetic dietary fibers are used because of their food functionality meaning they can be easily incorporated into products to increase the dietary fiber content with minimal impact on sensory properties he said. Manufacturers are aware that a product s flavor is just as important as any other factor but containing health benefits is certainly a positive attribute. Jolanda Vermulst manager of market intelligence at ingredient manufacturer Sensus (The Netherlands) explained fiber s potential for diabetes and cancer prevention. Fiber has an important role in the gastrointestinal tract she said. Whilst it is still an issue under scientific debate many studies have indicated that high dietary fiber intake could help in prevention of colorectal cancer and type 2 diabetes. Furthermore there are additional pros that suppliers and consumers may not be aware of. Dietary fibers are added to functional foods to provide physiological health benefits to consumers said Dr. TP Rao assistant general manager at Taiyo Kagaku Co Ltd Japan an ingredient manufacturer that produces SunFiber a soluble dietary fiber ingredient. Food or beverage items such as those products for weight loss (appetite control) glycemic reduction body building (high protein diets etc. would benefit from containing some added fiber. Rao said that in regard to weight loss these types of products would benefit from including a dietary fiber that offers a substantiated satiety effect. While most people understand that satiety is the lack of hunger it should be noted that we are talking about a comfortable-satiety or in other words satisfied and therefore not hungry. This is different from not-hungry because of feeling bloated and uncomfortable. SunFiber is a soluble dietary fiber that has a clinically sub- November December 2016 stantiated satiety effect. Being that these products are components of the natural products industry natural fiber is also in high demand. Research has confirmed that consumers continue to be focused on healthier lifestyles with particular interest in natural fiber noted Jon Peters president of New Jersey-based BENEO Inc. manufacturers of natural food ingredient products. Consumer research results show a clear preference for natural products--with as many as 47 percent of respondents actively seeking natural fibers--and 45 percent considering nonGMO (genetically modified organism) products as better. BENEO s chicory root fibers (inulin and oligofructose) are thus gaining great momentum among food and beverage manufacturers. Worldwide the food industry is showing a very high interest in the chicory root fibers inulin and oligofructose. Both are the fibers that are used most in new product developments during the past 12 months (Innova Market Insights 2016). As a result of the excitement toward fiber innovation this sort of feedback provides a sneak peak on how the market is playing out. Fiber Research As a supplier or manufacturer it is important to always be aware of how foods can be classified. Every company has a preference. Two types of fiber claims can be made on food products 1. Structure function claims or claims of well-being which require that the food contains 10 percent of the daily value (DV) and 2. Health claims said Welsh. While some generic dietary fiber claims exist (eg. fiber-containing grain products fruits vegetables and cancer) consumer package goods companies and consumers prefer fiber sources that have been studied extensively and can carry claims with significant scientific agreement (e.g. soluble beta-glucan from oats and risk of heart disease). ingredient as healthy simply by showing it as a fiber. That has changed. To be considered a dietary fiber ingredients now must demonstrate actual health benefits. The ingredient has to stand on its own not simply ride on the label of being a source of fiber. The inquisitive nature of today s society is what allows the world to keep progressing. Down the Road Just as history often comes full circle the same can be said about research. The only difference is that as time progresses research becomes more advanced. Beginning in the 1980s fiber researchers began shifting their research focus from the definition and analytical methods used to measure dietary fiber content to studies on the physiological impact of fiber consumption--cholesterol reduction satiety blood glucose regulation and laxation said Welsh. There was increased effort to measure the end products of bacterial fermentation in the large bowel--short chain fatty acid production gas production microbial mass etc. Today molecular genotyping allows researchers to quantify microbial populations and report shifts in species attributable to diet and physical activity. Peters pointed out that BENEO s chicory root fibers inulin and oligofructose have been the subject of more than 20 years of nutrition research and are among the best-researched prebiotic fibers worldwide. The studies provide a comprehensive body of evidence and to date more than 150 high-quality human intervention studies for inulin and oligofructose are available. The studies deliver strong evidence for distinct health benefits including digestive health (prebiotic effect bowel function) weight management (eating less naturally) blood glucose management and bone health (calcium absorption). Research and studies are an important indicator of health benefits--in this case the greater the quantity of studies the clearer one s results will be. NIE State of the Market Fiber s advantages are well known to most consumers. However one of several issues is the fact that an average person s diet in the United States may be lacking a significant amount of it. There is a strong understanding of the link between fiber and overall health although diets in Western countries remain dramatically deficient in fiber noted Julie Imp rato marketing manager with Nexira (France) an ingredient supplier that produces Fibregum an allnatural soluble dietary fiber. This is why the dietary fiber market is still growing. Peters agreed. So what does an acceptable daily value of fiber consist of U.S. consumers are aware of the beneficial effect fibers have on their overall health and well being but the majority of them have difficulties reaching the recommended daily intake of fibers which is 27 g day for women and 32 g day for men he said. Both for women as for men in the U.S. there is a lack of fiber intake (averaging 12-15 g day). This is why fiber-fortified products that can be easily integrated into the daily diet are increasingly in demand. Such facts influence what ingredient suppliers and manufacturers are interested in when creating their products. Research has confirmed that consumers continue to be focused on healthier lifestyles with particular interest in natural fiber. -- Jon Peters President BENEO Inc. Gone are the days when individuals simply believed what is written on a label. Rather people want to see proven results--this would include trials and studies that were conducted showing physical proof. Knowledgeable consumers are no longer satisfied with one or two research trials. Research for today s dietary fibers should provide an entire body of evidence added Bill Driessen director of technical sales (Central U.S. and Latin America) at Taiyo International Inc. in Minnesota. It s not enough to simply evaluate an ingredient and identify it as dietary fiber. Previously an ingredient could show that it could be considered a fiber (indigestible carbohydrate) he added. Fiber was is considered healthy so an ingredient company could tout their FORMOREINFORMATION BENEO Inc. (973) 867-2140 DSM North America (Royal DSM) (973) 257-1063 Nexira 33 (0)2 32 83 18 18 Sensus 31165 58 25 49 Taiyo International Inc. (763) 398-3003 Taiyo Kagaku Co. Ltd. 81-90-4857-3422 Nutrition Industry Executive 37 November December 2016 Conventions&Meetings Health & Nutrition Week U BM event organizer of food ingredients events with a U.S. corporate office in New York has announced that it will be hosting the Health & Nutrition Week in Frankfurt Germany from November 28 to December 2 with the support of Messe Frankfurt. This week-long festival will feature a series of activities such as a 465-plus strong exhibitions meetings lectures panel discussions and other events which will bring the global health and nutrition community together including worldleading experts. The focus of the Health & Nutrition Week is the Health Ingredients Europe and Natural Ingredients the world s most important gathering of those offering and in search of natural and health ingredients. For more information visit or The Mexican Healthy Products Summit T he Sheraton Buganvillas Resort and Convention Center in Puerto Vallarta Mexico will be home to the Mexican Healthy Products Summit which will be held January 27-29 2017. This is an invitation-only business-to-business trade show and conference linking healthy products suppliers with key retail buyers and distributors. There will be a variety of networking opportunities including a welcome reception evening cocktail gatherings meals (breakfast lunch and dinner) and entertainment. Expert speaker session will be in the morning with topics ranging from the Latest Healthy Lifestyle Trends in Mexico Natural Marketing Institute (NM) to How to do Business in Mexico U.S. Commercial Service Office. For more information visit MarketingInnovations (Continued from page 35) thank them for their time and provide additional information identified in the meeting. If the show is in the fall ask about their editorial calendar for the following year and if they are open to you sending them suggestions on topics to which you could contribute information. Here s a quick completely subjective overview of the major industry shows related to dietary supplements that take place in the U.S. from the perspective of our collective 35 years going to them chronologically Natural Products Expo West March Anaheim CA (New Hope Penton). The granddaddy of the shows with brands exhibiting to natural product retailers and a separate ingredients pavilion. This show has become so massive that it overflows from the Convention Center to include booths meetings and events in the nearby Hilton and Marriott. Traditional place to launch new products. Just hold on and try to survive but leave inspired. You get to see all your industry friends. Ingredient Marketplace April Orlando FL (Informa). Very focused ingredients exhibited to manufacturers. Excellent networking and education. The smaller of the two Informa supplyfocused shows. IFT June or July rotates between Chicago IL Las Vegas NV and New 38 Nutrition Industry Executive Orleans LA. Hosted by the Institute of Food Technologists this show emphasizes the technology aspect of producing food and related products with food and supplement ingredients and equipment exhibiting to manufacturers. Includes scientific poster sessions and education. Expo East September Baltimore MD (New Hope Penton). Finished product manufacturers exhibiting to retailers. Much smaller than Expo West so it s a lot easier to stand out and get people s attention. Good education program. SupplySide West (SSW) Conference & Expo September or October Las Vegas NV. Ingredients and equipment exhibited to manufacturers. For many people SSW has become the most important show of the year for networking and education. Just celebrated 20th anniversary and is now where several trade associations meetings take place. Internationally Informa s VitaFoods shows are well attended and a significant number of companies that exhibit at some of the U.S. trade shows also participate in these as well particularly VitaFoods-Europe. Informa (SupplySide West Ingredients Marketplace VitaFoods) is in the process of buying Penton (Expos West and East) so there may be changes to some of these shows over the next few years that impact which are best for you and how to approach them. See you in Anaheim NIE The Shelton Group is a boutique public relations and marketing agency working exclusively in the dietary supplements and natural products industry since 1990. Suzanne Shelton has provided public relations services to both international and domestic dietary supplement and natural products manufacturers suppliers and associations. Contact her at suzanne Todd Pauli works with clients to develop comprehensive marketing strategies that integrate social media advertising and content marketing. Prior to joining The Shelton Group Pauli led marketing communications efforts for several well-known businesses including NOW Foods one of the largest supplement manufacturers in the natural channel. Contact him at Todd November December 2016 Equipment&Packaging Deitz Company Innovation Eases Printing on Bottles for Traceability The new Pharmafill BCV1 Bottomless Conveyor from New Jersey-based packaging machinery manufacturer Deitz Co. enables serial numbers lot codes and other markings to be easily printed on the bottoms of plastic and glass bottles without requiring the bottles to be slowed stopped rotated diverted or otherwise disrupted from their flow in the packaging line. Ideal for nutritional supplement bottles pharmaceuticals and other products where identification and or traceability are required or desired the clever BCV1 Bottomless Conveyor accepts containers from a standard conveyor that drops out from under the bottles as dual side belts gently grip and convey the bottles over a laser marking device thermal inkjet printer continuous inkjet printer or other coding system. When marked the BCV1 Bottomless Conveyor releases the bottle to the next stage in the packaging line. The Bottomless Conveyor technology also may serve as an active transfer mechanism to transfer bottles and other containers from one point to another instead of using dead plates or other passive diverters which require back pressure from the containers. The BCV1 hugger belt conveyor may be easily adjusted in width and in height to accommodate a wide variety of bottle shapes and sizes and may be mounted on a conveyor or set on a sturdy adjustable-height lift stand. For more information call (732) 681-0200 or visit Sanitary High-intensity Continuous Blender A new sanitary high-intensity continuous blender Model HIM-124S316 from New York-based Munson Machinery provides low to high shear as required for high speed blending and or homogenizing of dry solids agglomerates slurries or pastes when processing food chemicals pharmaceuticals or other contamination-sensitive materials. Homogeneous blends can be achieved in as little as 20 seconds residence time depending on material characteristics at throughput rates to 200 cu. ft. h (5.7 m3 h). Liquids can also be added in small to large amounts through optional injection ports for de-dusting and agglomerating of dry materials as well as for producing pastes emulsions and slurries. The unit s horizontal cylindrical vessel with a single high-speed rotating agitator is supported by externally mounted bearings with sanitary type seals. Large radius welds joining the large-diameter solid shaft to blending paddle standoffs allow rapid cleaning and sanitizing. For more information call (315) 797-0090 or visit Inflatable Packaging System Replaces Packing Peanuts Opti NX Shrink Film A new 475 inflatable packaging system from Sealed Air in Illinois provides a space-saving cost-saving and environmentally friendly alternative to using polystyrene peanuts as void-fill and cushioning in packing boxes. The new Fill-Air FLOW system makes protective air pillows affordable for users with low-volume shipping needs for the first time. Available exclusively in the U.S. from Illinois-based Millennium Packaging for less than half the price of similar products the compact Fill-Air FLOW machine mounts to a wall or tabletop and produces 11 high-fill or 20 low-fill inflated plastic bags per minute. Both the machine s 13- by 14- by 8-inch footprint and the inflation speed are suited to environments with moderate shipping volumes such as retail shipping service centers retail stores e-tailers light industry company mail rooms marketing and advertising agencies and more. Sealed Air is also introducing Opti Next Generation Shrink Films from Millennium Packaging. The new film supplies up to 30 percent more footage in the same footprint and at the same price as competitive products yielding key cost material use and production advantages. These benefits stem from patented Sealed Air 29-micro-layer technology that produces a thinner gauge with better tear resistance and better clarity than many thicker films. The Opti NX also has a wider sealing and shrinking range than standard films. For more information call (888) 914-2244 or visit or November December 2016 Nutrition Industry Executive 39 Supply Innovation F or more than a decade Nutrition Industry Executive (NIE) has strived to cultivate relationships between ingre- Following is the list of companies participating in this year s Supply Innovation section Albion Laboratories Inc. ...............................41 dient suppliers and finished product manufacturers by providing Science of Ingredients sections to highlight the research supporting ingredients that can help finished products stand out. In the interest of furthering that cause and providing greater insight into suppliers efforts NIE offers its Supply Innovation section. Comar LLC .....................................................42 Jiaherb Inc.....................................................43 NutraGenesis TradeWorks Group ................44 Icon Group Sabinsa Corporation ......................................45 U.S. Pharmacopeial Convention (USP) ..........46 NIE has given companies a chance to highlight their latest most innovative offerings. NIE has also provided ample company information to foster immediate connections with parties interested in learning more. 40 Nutrition Industry Executive November December 2016 Supply Innovation Albion Laboratories Inc. 67 S. Main St. 100 Layton UT 84041 Phone (800) 453-2406 Fax (801) 773-4633 Email tjohnson Website Proven Mineral Forms for Every Nutritional Application B alchem Corporation offers a complete line of nutritionally essential minerals through the Albion brand of chelated and organic minerals. Minerals are essential to life but cannot be manufactured by the body. With Albion science and patented technology have been combined to create an organic molecule in a form the body can readily assimilate. These special organic forms of mineral elements are mineral amino acid chelates. Inorganic sources of minerals can cause irritation of the gastrointestinal tract and even toxicity with larger doses. Supplementing diets with inorganic minerals can also cause mineral interactions which may suppress rates of absorption. Albion minerals chelated with amino acids have shown greater bioavailability and utilization in humans. Less irritation has been indicated in human studies from ingesting these minerals as metal amino acid chelates. Albion pioneered the use of FastFourier Transforming Infrared spectroscopy (FT-IR) to identify the bonds between the ligand and mineral and to verify the molecular structure is that of a true chelate. Without this test for quality assurance manufacturers and consumers have no way of knowing whether a mineral is truly chelated. With more than 150 patents Albion is continuously working on new technology and manufacturing advances and researching ways to improve mineral delivery systems. Albion builds a better mineral in six steps 1. Start with high-quality raw materials 2. Use patented chelation technology 3. Select quality ligands 4. Use proven manufacturing processes 5. Test for quality using FT-IR 6. Continue lab and clinical research Albion chelated minerals offer the following unique advantages Calcium is an essential mineral for a wide range of health-promoting functions including supporting colon health maintaining healthy blood pressure building dense healthy bones and teeth and supporting healthy weight management. Calcium absorption is complex but with Albion chelated calcium products less dietary interaction means greater absorption and increased bioavailability. Additionally solubility and sensory factors make certain calcium compounds more suitable for one application over another. The Albion line of calcium compounds has the chemical and physical properties to fit most fortification and supplement needs. With Albion science and patented technology have been combined to create an organic molecule in a form the body can readily assimilate. Iron deficiency is the most prevalent nutritional disorder in the world. Iron is an important component of hemoglobin which carries oxygen to tissues and helps fight fatigue. Iron is also essential to healthy cell function and helps form many of the proteins and enzymes that maintain good health. Ferrochel is a unique fully chelated iron product formed by binding iron to two organic glycine molecules. Compared to inorganic iron Ferrochel is more bioavailable and causes less gastric upset. It is safer than typical iron salts more bioavailable (easily absorbed) and has less interaction with other nutrients. This is especially important in multivitamins for pregnant and nursing mothers and for children. Magnesium is a crucial macro mineral involved in more than 300 physiological processes. It is essential to body structure and healthy function. Research studies have shown that magnesium supports bone health cognitive health energy production cardiovascular health muscle strength and relaxation. There are several forms of Albion magnesium amino acid chelates which have been clinically demonstrated to be among the most bioavailable stable and well-tolerated forms of magnesium available. Other offerings include organic salts of aspartic acid and a patented dimagnesium malate as well as Creatine Magnapower a magnesium creatine chelate ideal for sports nutrition applications. Zinc is a trace mineral needed by more than 300 enzymes to repair the body and support the immune system. It also helps synthesize proteins helps cells reproduce and helps maintain fertility in adults. Strenuous exercise depletes zinc stores and low zinc levels in the muscles correlate with reduced endurance capacity. The zinc manufactured by Albion is a totally reacted nutritionally functional zinc bisglycinate chelate. In a clinical study comparing the oral bioavailability of zinc bisglycinate chelate to zinc gluconate Albion s chelated form increased absorption more than 43 percent. In addition Balchem has Albion mineral offerings in boron copper chromium manganese potassium selenium and vanadium. Finally Balchem also offers an essential vitamin as an ingredient. Choline is essential for single carbon metabolism neural function and cognitive health. After many years of study an RDI (recommended daily intake) for choline was established this year recognizing its essentiality. Today a large part of the population does not consume enough choline in their diets necessitating supplementation. Choline plays a key role in cholinergic memory function and is essential during natal development and throughout life. Choline also contributes to cell membrane integrity as part of the phospholipid membrane. Balchem is the leading manufacturer of choline and offers its branded Vitacholine as a premium quality ingredient. Nutrition Industry Executive 41 November December 2016 Supply Innovations Comar LLC 1 Comar Pl. Buena NJ 08310 Phone (800) 962-6627 Fax (856) 692-9252 Email marketing Website Lock in Reduced Packaging Costs With One-piece Child-resistant Closures The Comar SecureCap QuarterLoc child-resistant closure helps manufacturers lower packaging costs by 10 to 25 percent. C omar a leading designer and manufacturer of quality health care packaging products introduces the new SecureCap QuarterLoc child-resistant closure a one-piece push and turn bottle cap that requires only a quarter turn to apply or remove. QuarterLoc offers manufacturers of prescription medications and over-the-counter products a reduction in part weight assembly steps and production costs. Designed to be compatible with multiple products the Comar SecureCap QuarterLoc closure design has passed Consumer Product Safety Commission testing protocols for both child-resistance and senior-friendly performance. For over-the-counter and prescription medicine manufacturers compliance with the CPSC requirement for child-resistant packaging may result in delays and costly retooling of filling processes. The design of the SecureCap QuarterLoc CR closure offers a solution because it is easily integrated into existing packaging lines. QuarterLoc is both adaptable and scalable for multiple products and is an efficient child-resistant solution. Our SecureCap QuarterLoc is useful for vitamin mineral and supplement products--and especially for gummies because of its proven childresistant performance said LouAnn Evans director of strategic marketing at Comar. We re helping to deliver child-safe performance while lowering manufacturing costs. In order to offer customers a complete system Comar has also developed HDPE bottles with 38 and 53 mm neck finishes especially for use with QuarterLoc closures. SecureCap QuarterLoc is manufactured from polypropylene. The onepiece design reduces manufacturing complexity and is more environmen42 Nutrition Industry Executive tally responsible. By providing a secure closure with just a quarter turn QuarterLoc is easier to use because it eliminates the potential of thread misalignment and cocked caps. The closure does not require a liner but can accommodate a single layer foil induction liner or an in line conduction liner. The Comar SecureCap QuarterLoc is protected by patents and manufactured in facilities that meet current good manufacturing practices (cGMP) and ISO 9001 13485 quality standards. For additional information or samples call (800) 962-6627 or email marketing About Comar Comar LLC a company defined by its devotion to quality service and creativity is committed to protecting and enhancing the health and wellbeing of everyone. The company is a leading manufacturer of plastic dosing and dispensing products bottles containers and closures. Comar s expertise with all the major rigid plastic processing platforms including injection molding extrusion blow molding injection blow molding and injection stretch blow molding is available from six North American manufacturing facilities allowing us to provide a global customer base in health and wellness personal care specialty food household and light industrial markets with a broad array of proprietary products custom molding printing and complex assembly capabilities. For a safe innovative solution to containing and delivering your high-value product come to Comar. November December 2016 Supply Innovations Jiaherb Inc. 1 Chapin Rd. Unit 1 Pine Brook NJ 07058 Phone (973) 439-6869 Fax (973) 439-6879 Email info Website Highest Quality Standards s the largest NSF-GMP (good manufacturing practice) certified natural ingredient manufacturer in China Jiaherb Inc. offers more than 600 ingredients regularly stocked in both of the company s more than 50 000-square-foot New Jersey and California locations. Using a comprehensive and diverse sourcing program Jiaherb s dedicated sourcing team travels the world to find the top raw materials allowing its customers full product traceability. To guarantee the highest quality standards the company works closely with the premier growers and pickers using stringent quality control practices and examining each batch of raw material in our state-of-the-art laboratory for identity potency and purity. The experience and reliability of Jiaherb s production team allows the company to produce thousands of metric tons of natural ingredients per year resulting in short lead times on orders. Along with Jiaherb s USDA (U.S. Department of Agriculture) Organic and Orthodox Union Kosher products Jiaherb offers a number of NonGMO (genetically modified organism) Project Verified products. The company is dedicated to complying with their extensive verification process testing and traceability practices to assure that its customers are receiving the best quality product on the market. Jiaherb s quality control and assurance team uses the most advanced equipment for analytical testing certifying the transparency and safety of all its products. Run by skilled scientist and technicians the company s inhouse laboratories are equipped with extensive systematic instrumentation including but not limited to HPLC UPLC GC UV ICP-MS HPTLC FTIR PPSL and pesticide and microbiology testing. Research and development work to identify current and future market demands combining their proficiency with the latest technological innovations to develop unique products keeping Jiaherb s customers one step ahead of the rest. A To guarantee the highest quality standards the company works closely with the premier growers and pickers using stringent quality control practices and examining each batch of raw material in our state-of-the-art laboratory for identity potency and purity. November December 2016 Nutrition Industry Executive 43 Supply Innovations NutraGenesis TradeWorks Group Icon Group 167 Main St. Ste. 208 Brattleboro VT 05301 Phone (802) 257-5345 Fax (802) 251-6981 Email bruce Website WellBody 365 ellBody 365 helps support enhanced sports performance immune health focus and stress reduction maintaining optimal health energy and focus is important when you push your body to the limit in the gym on the field or during endurance training. These activities often result in stress on the body which can lead to fatigue delayed recovery cognitive issues immune challenges and more. Sports performance can be enhanced by WellBody 365 a scientifically researched proprietary botanical mushroom blend consisting of self-affirmed GRAS (generally recognized as safe) ingredients including Sensoril Ashwagandha (Withania somnifera) full spectrum root and leaf extract and MaitakeGold 404 maitake (Grifola frondosa) mushroom fruit body extract. WellBody 365 possesses substantiated structure function claims in a number of sports nutrition-related areas and is regulatorily compliant. W WellBody 365 possesses adaptogenic properties that help promote greater energy immune support and cognitive function through stress reduction and immune modulation. reduced fatigue and greater concentration.1 These adaptogenic properties are desired by athletes who want to increase their energy level reduce recovery time and also enhance focus during sports activities. Sensoril to create WellBody 365 healthy immune support in stressed conditions is even more apparent as was demonstrated in an elegant invivo experiment conducted at the University of Louisville.3 Mice fed a normal diet were stressed using a well-established model resulting in decreased immune function compared to nonstressed control animals. In contrast mice fed a diet that included WellBody 365 showed physiological responses that indicated a reduced level of stress even when the WellBody 365-fed mice were exposed to stressful conditions. The WellBody 365-fed mice also had significantly greater immune function compared to stressed control animals. These combined results demonstrate the breadth of WellBody 365 s comprehensive immune support and stressreducing properties. WellBody 365 Can Be Utilized in Many Applications WellBody 365 s scientifically researched properties help reduce stress enhance energy and concentration and support healthy immune function which can help promote greater sports performance. In addition WellBody 365 is regulatorily compliant and possesses substantiated structure function claims in accordance with DSHEA (Dietary Supplement Health and Education Act of 1994). It can be utilized in many applications based on its solubility in water heat stability vegan and gluten-free status and cost effectiveness. WellBody 365 Possesses Adaptogenic Properties WellBody 365 possesses adaptogenic properties that help promote greater energy immune support and cognitive function through stress reduction and immune modulation. Adaptogens help bring balance and homeostasis to the body after it has been affected by various types of stressors. Ashwagandha a revered ayurvedic adaptogen containing glycowithanolide bioactives has been used extensively for thousands of years to address physical and mental stress as well as fatigue. Maitake mushroom which contains beta-glucan bioactives has also been used for thousands of years in the East to help support healthy immune function. In a randomized double-blind placebo-controlled human clinical trial subjects taking the amount of Sensoril in the recommended dose of WellBody 365 experienced significant improvements in the level of stress and stress-related effects including 44 Nutrition Industry Executive WellBody 365 Helps Promote Healthy Immune Function When Stressed Healthy immune support in the area of sport nutrition is especially important for endurance athletes due to the stressful effects of long distance exercise on respiratory health. By itself under normal conditions MaitakeGold 404 nutraceutical extract has been shown in scientific testing (including human clinical trials) to help enhance immune health including important individual components of the body s immune system.2 Scientific testing has shown that MaitakeGold 404 also helps support immune health after stress has affected immune function.3 When MaitakeGold 404 is combined with References 1 Auddy B et al. 2008. A standardized Withania somnifera extract significantly reduces stress-related parameters in chronically stressed humans A double-blind randomized placebo-controlled study. JANA 11 50-56. 2 Vetvicka V and Vetvickova J. 2005. Immunostimulating properties of two different beta-glucans isolated from Maitake mushrooms (Grifola frondosa). JANA 8(3) 33-39. 3 Vetvicka V and Vetvickova J. 2011. Immune enhancing effects of WB365 a novel combination of Ashwagandha (Withania somnifera) and Maitake (Grifola frondosa) extracts. N Am J Med Sci 3(7) 320-324. November December 2016 Supply Innovation Sabinsa Corporation 20 Lake Dr. East Windsor NJ 08520 Phone (732) 777-1111 Fax (732) 777-1443 Email info Website uC3 CLEAR Raise a Glass to Curcuminoids C urcuminoids the versatile cascading and long-lasting pronutrient is undoubtedly the most important and precious gifts to mankind from nature. A common spice used in South Asian cooking turmeric and more appropriately the component curcuminoids have been preclinically and clinically validated for their beneficial role in maintaining health and wellness. They offer antioxidant support anti inflammatory support support for a healthy immune system and the potential to prevent connective tissue break down through inhibiting destructive enzymes with benefits in healthy aging. At the molecular level curcuminoids have been shown to inhibit nuclear factor kappaB (NFkB) a transcription factor that triggers inflammatory mediators. NFkB is implicated in a variety of chronic disease conditions ranging from cardiovascular diseases to cancer. While more than 45 human clinical studies have been published and continue to emphasize the relevance and importance of curcuminoids in general health and wellness more than 50 pre-clinical studies have also been carried out for a range of applications unraveling the mechanisms at the cellular level. Sabinsa has more than 27 years experience in the field of standardized extracts and with the chemistry and properties of turmeric. The team of scientists at Sabinsa while working on this traditional herb turmeric derived an optimized composition of curcuminoids from rhizomes of turmeric to provide the maximum antioxidant or bioprotectant activity. This composition was later patented by Sabinsa. This unique and patented composition of curcuminoids is available under the brand name Curcumin C3 Complex. Curcumin C3 Complex achieved a major landmark in 2013 when it received no comment letter from the FDA (U.S. Food and Drug Administration) which meant that Sabinsa s Curcumin C3 Complex achieved GRAS (generally recognized as safe) status and now could be used in food categories as well. With all the above benefits delivery of curcumin in the form of a drink has always been a challenge due to poor solubility resulting in sedimentation. Several methodologies have been attempted by many to improve the solubility such as use of polymeric substances nano particle synthesis lipophilic formulations and so on. The safety of these forms of curcumin and their excipients to increase the solubility has always been an issue of concern. uC3 CLEAR is an improved convenient delivery system for curcumin that overcomes the basic challenges and limitations that can be present with solid dosage delivery systems such as poor disintegration slow dissolution or difficulty swallowing thus enhancing the uptake of curcumin. Sabinsa s uC3 CLEAR is Water soluble A compatible form of curcuminoids in beverages Free from nano-technology Visually appealing The use of standardized extracts in different dosage forms such as tablets capsules and soft gels is well known. However their incorporation in functional foods and beverages is in recent times more widely accepted and preferred. The challenge is to solubilize plant based extracts that are safe effective and compatible in beverages. With this background the development of uC3 CLEAR is the culmination of a wide range of experiments that have gone into formulating a water soluble form of curcumin. With equal and vast knowledge on scientifically validated natural extracts and the formulation of functional foods using these ingredients Sabinsa has delivered its water soluble curcumin extract--uC3 CLEAR. uC3 CLEAR is standardized for 10 percent curcuminoids and forms clear solution with water. Curcumin with its multifaceted biochemical mechanisms and in its water-soluble form remains the unparalleled natural molecule of interest--in the past present and future. With all the health and wellness benefits of natural curcuminoids packed in a compatible form uC3 CLEAR is here to deliver one of the most powerful natural extracts of the century. Nutrition Industry Executive 45 November December 2016 Supply Innovation U.S. Pharmacopeial Convention (USP) 12601 Twinbrook Pkwy. Rockville MD 20852-1790 Phone (301) 881-0666 (800) 227-8772 Email mediarelations Website USP Verified Mark R ecent reports challenging the quality of dietary supplements have prompted industry leaders and health professionals to find ways to distinguish quality products from subpar products as they strive to protect their brands and consumers. A prominent solution that manufacturers health professionals and consumers have relied upon is to look for the USP Verified Mark. Pharmacists Know and Trust USP Verified Pharmacists are strong proponents of the USP Verified Mark primarily because they are familiar with USP s role in establishing quality standards for medicines. Since 1906 Congress has required that medicines sold in the U.S. meet public standards and recognized the US Pharmacopeia and the National Formulary or USP and NF as official compendia of those standards. Pharmacists are accustomed to seeing the letters USP on the medicines they dispense. So when the quality of dietary supplements are challenged it is not surprising that they would look to USP for an assurance of quality. How can we protect patients in this milieu asked Cydney McQueen PharmD in a guest editorial published in the March 2016 issue of the journal Hospital Pharmacy. Her answer Provide education on the problem of quality and practical guidance on how to navigate store shelves. Her top recommendation for both pharmacists and consumers is to look for third-party verification of quality specifically the USP Verified Mark. Sarah Erush PharmD clinical manager of the Pharmacy at the Children s Hospital of Philadelphia took this approach one step further and required her hospital pharmacy to try to only stock dietary supplements that have been independently tested for product quality. She also prefers the USP Verified Mark. this law was that it created a disincentive for what had been an accepted practice adding the letters USP after the product or ingredient name to indicate it was made to USP standards. But many manufacturers still wanted a way to indicate their products were made using USP s rigorous science-based standards. So at the request of industry USP created USP Verified a voluntary independent third-party verification program based on USP standards to help address their concerns. The USP Verification process includes facility audits full document review of quality control procedures and testing products against USP s public standards. Products that meet USP s rigorous procedures are awarded the USP Verified Mark. The USP Verified Mark offers assurance that what s on the label is in the bottle in the right amount it has been tested for harmful levels of contaminants and will break down so it can be absorbed by the body. Early participants in the program were NatureMade and Costco s Kirkland Signature brand. The USP Verified Mark makes a participant s commitment to quality visible and helps differentiate their products in a competitive marketplace. and test methods for all of the botanical extract products and ingredients targeted by the NYAG. None of these standards currently include DNA test methodology. None of the brands cited in the NYAG s letters were USP Verified. If they were USP would have conducted an investigation to ensure they complied with standards found in the USP-NF and USP would stand by the quality of those products. Media Reports Advise Readers to Look For the Mark Increased scrutiny of the dietary supplement industry did not end with the investigation by the NYAG. Federal enforcement actions against a few manufacturers of products primarily in the sports sexual enhancement and weight-loss segments included product recalls and other events making dietary supplement quality a steady focus of news reports over the past year. Many stories have pointed to USP Verified and other third-party seals as a way to help consumers choose quality products. Demand for Verification Seals is Growing The supplement industry is under unprecedented scrutiny. Reports of poor quality among products in a few segments have called into question the quality of almost all products. And independent verification seals are popular and a useful tool to help distinguish quality products. Pharmacists national brands major retailers and the media rely on these seals to help patients consumers and readers determine quality products. Consumers are learning to look for the USP Verified Mark to ensure what s on the label is what s in the bottle. As a result interest in the USP Verified program is growing. More information about the USP Dietary Supplement Verification Program can be found at Retailers Can Look to USP Verified to Manage Risk In February 2013 the New York attorney general (NYAG) sent cease and desist letters to several major retailers demanding they remove some of their herbal dietary supplement products from store shelves because tests using DNA methodology showed they did not contain the ingredients listed on the label. Although the test methods used by the AG s office were challenged the move garnered negative press for those retailers and the industry. Among the 500-plus quality standards for dietary supplements and dietary ingredients in the USP-NF are standards Industry Appeals to USP to Help Make Quality Visible When Congress created a separate regulatory category for dietary supplements in 1994 it continued to recognize USP standards as official but made them voluntary. An unintended consequence of 46 Nutrition Industry Executive November December 2016 Advertiser Index Albion Laboratories Inc. Comar LLC Herbally Yours HSU s Ginseng Enterprises Inc. Jiaherb Inc. KML Laboratories Inc. Now Foods PL Nutragenesis Icon Group PLT Health Solutions Sabinsa Corporation Soma Labs Inc. United States Pharmacopeia 7 9 12 13 5 22 1 C3 3 C2 23 C4 (801) 773-4631 (856) 507-5402 (480) 892-8220 (800) 388-3818 (888) 542-4372 (208) 267-0818 (800) 999-8069 (802) 257-5345 (973) 984-0900 (732) 7 7 7 - 1 1 1 1 (732) 271-3444 (301) 230-6361 albion comar herballyyours hsus jiaherb kml nowpl nutragenesis plt sabinsa somalabs usp Industry Events November 15-17 Advanced Manufacturing Expo & Conference Centro Banamex Mexico City Mexico February 7-9 2017 West Pack Anaheim Convention Center Anaheim CA (310) 445-4200 March 8-12 2017 Engredea at Natural Products Expo West Anaheim Hilton & Marriott Anaheim Convention Center Anaheim CA (866) 458-4935 or April 18-20 2017 Ingredient Marketplace Orlando World Center Marriott Orlando FL May 9-11 2017 VitaFoods 2017 Geneva Palexpo Geneva Switzerland (Continued from page 30) and Lp(a) and elevating HDL-C concentrations (Panahi et al. 2014 Complementary Therapies in Medicine. 22(5) 851-857). In addition curcuminoids from the rhizomes of Curcuma longa have the potential to reduce biomarkers of systemic inflammation Majeed noted adding that well-recognized among them are NF-B TNF- COX-2 and selected interleukins. With respect to high blood sugar levels TNF- and interleukin 6 (IL-6) are considered as the most important cytokines responsible for chronic low-grade systemic inflammation also called metabolic inflammation. This is commonly associated with metabolic disturbances such as type 2 diabetes. Pro-inflammatory cytokines have been reported to induce the development of insulin resistance by altering the insulin-signaling pathway or via triggering inflammatory pathways. There is some evidence that curcuminoids inhibit these inflammatory markers and can play a vital role in managing elevated blood sugar levels. In a randomized double-blind placebo-controlled parallel-group clinical study conducted by researchers at Baqiyatallah Hospital in Iran 117 subjects with metabolic syndrome were enrolled and randomized either to receive Curcumin C3 Complex with BioPerine (1 000 mg 5 mg day) or matching placebo for eight weeks. At the end of the study a significant difference in several inflammatory markers was observed which corroborated with ideal blood sugar levels. (Panahi et al. 2016. Biomedicine & Pharmacotherapy 82 578 582) Similarly See noted that EVNol SupraBio doesn t directly address blood sugar imbalance. However in recent human clinical studies oral supplementation of EVNol SupraBio has shown significant result in supporting healthy cholesterol blood pressure inflammation markers (cytokines levels) and fatty liver in adults with metabolic syndrome. In 2012 researchers at Stanford University School of Medicine reported that people with fatty liver disease were significantly more likely to develop type 2 diabetes mellitus within five years than those with healthy livers. Science Daily has also reported that patients who have NAFLD are at a high risk of developing end-stage liver diseases cirrhosis diabetes and cardiovascular diseases (heart attack stroke etc.). NAFLD can be considered as a precursor for diabetes. While awareness among consumers that herbs and supplements can support good health and minimize the likelihood of developing many conditions has increased whatever a consumer chooses See noted that they must discuss with their doctors before they start taking supplements for healthy blood sugar support. NIE Extra Extra For more information on Bergamonte and metabolic syndrome visit FORMOREINFORMATION ExcelVite Inc. (732) 906 1901 Frutarom Health 32 52 319 532 HP Ingredients (877) 437-2234 Natreon Inc. (732) 296-1080 Pharmachem Laboratories Inc. (800) 526-0609 Sabinsa (732) 777-1111 Wisdom Natural Brands (800) 899-9908 Nutrition Industry Executive 47 November December 2016 SupplieroftheMonth Lynda M. Doyle MS Human Nutrition Senior Vice OmniActive Health Technologies 67 E. Park Pl. Ste. 500 Morristown NJ 07960 Phone (866) 588-3629 Website OmniActive Health Technologies offers a range of ingredients that are innovative and scientifically validated to address complex President of challenges for customers in the dietary supplement food and Global Marketing beverage space using technology-driven sustainable solutions with application support within a global regulatory framework. OmniActive s core products include carotenoids plant extracts and specialty functional ingredients. OmniActive leverages international R&D strengths to deploy an array of state-of-the-art manufacturing technologies in extraction purification isolation and delivery of nutritional actives. Clinical research geared towards demonstrating efficacy and claim substantiation is the cornerstone of OmniActive s R&D activities. The company s centers of excellence are located in North America and India whereas its cGMP (current good manufacturing practices) and HACCP system-compliant manufacturing operations are located at multiple FDA (U.S. Food and Drug Administration) inspected sites in India. Lynda Doyle has extensive nutrition marketing and business development experience having spent nearly three decades working in the dietary supplement and functional food industries with companies including DSM Nutritional Products Roche Vitamins BASF Corporation and Glanbia Nutritionals. Doyle is the current senior vice president of global marketing at OmniActive Health Technologies. NIE OmniActive recently won Pharmexcil s Gold Patent Award in the category of nutraceuticals as well as Best Quality Management Company of the Year and Nutraceutical Export Company of the Year from The Associated Chambers of Commerce & Industry of India (ASSOCHAM). What is the importance of recognitions such as these for the company Doyle Through the years OmniActive has been very fortunate in being recognized by a variety of prestigious global organizations in a myriad of categories including operational and manufacturing excellence innovative marketing and groundbreaking science. OmniActive has a devoted team and their dedication is at the heart of our accomplishments each individual taking pride in the collective win of these recognitions. These awards further validate our efforts and our vision--to improve lives by enhancing nutrition and wellness using science and innovation. Doyle Eye health is an ever-important consumer health platform--from neural development to visual performance to maintaining healthy vision as we age. OmniActive recognized the need to educate the industry health care practitioners and consumers and launched our award-winning educational campaign Lutein For Every Age. Lutein For Every Age raises awareness of the benefits of early and consistent intake of macular carotenoids--lutein RR- and RS (meso)-zeaxanthin--to help maintain eye skin and cognitive health at all stages of life. We have also expanded Lutein For Every Age to include macular carotenoids in healthy populations for visual performance cognition and stress and skin health through our robust clinical program and various marketing initiatives. With the growing breadth of science on the importance of the macular carotenoids and with the everincreasing exposure to high-energy blue light sources and expanding on the success of Lutein For Every Age What s Your B.L.U.E. (blue light user exposer) is a category-creating initiative to educate consumers on high-energy blue light its sources and ways to help protect healthy vision from its effects with the support of the macular carotenoids. More than ever before our eyes are being bombarded by high-energy blue light sources including electronic devices such as televisions tablets smartphones and computers as well as indoor lighting (CFL or LED) and even LED car headlights. High-energy blue light reaches deep into the eye and can harm the macula the region of the eye responsible for the highest visual acuity and sharpness. Lutein and the zeaxanthin isomers support eye health by acting as powerful antioxidants and filtering high-energy blue light. Our ground-breaking B.L.U.E. study has been a huge part of our What s Your B.L.U.E. campaign which investigated the impact of macular carotenoids on healthy subjects exposed to long-term use of digital devices screens and other blue light sources. This study supports specific claims based on practical human clinical evidence and not just theoretical research. NIE OmniActive is highlighting What s Your B.L.U.E and Lutein for Every Age. Please discuss the significance of these campaigns. 48 Nutrition Industry Executive Extra Extra Visit to read the rest of the interview. November December 2016 Go to nutragenesis for info about this advertiser Go to usp for info about this advertiser